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Temporal–spatial distribution and diastereoisomer pattern of hexabromocyclododecane in the vicinity of a chemical plant

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Journal of Environmental Sciences 2019年第8期31卷 203-212页

作者： Xinlei Wang ruirui sun Yuedong Chen Xu Zhang Zhaojie Cui School of Environmental Science and Engineering Shandong University Department of Plant and Microbial Biology University of Zurich

Hexabromocyclododecane(HBCD) is an effective brominated flame-retardant additive, which is mainly produced in the coastal area of China. This study collected soil samples from a HBCD production plant and its surrounding area in Weifang, Shandong Province, China, and analyzed the temporal–spatial distribution of HBCD and its diastereoisomers in soil. The analysis results showed that the concentration of HBCD in soil near the plant was much higher than normal values, with an annual average concentration reaching 5405 ng/g. Soils 1,2 and 4 km away from the plant were also analyzed, showing that the concentration of HBCD in soil decreased accordingly with the distance from the pollution sources. In order to investigate the effect of the season on HBCD content, the soil samples were collected in all four seasons of the year 2017–2018. According to variations in the wind direction, the concentration of HBCD in soil was also changed. The distribution trend showed that the concentration of HBCD in soil in the downwind direction of the prevailing wind was higher than that in the upwind direction. In addition, this work analyzed the distribution of HBCD in vertical soil sections. It was found that the concentration of HBCD decreased with depth in the soil vertical profile. Finally, the various diastereoisomer patterns in the soil compartments were examined, finding that α-HBCD and γ-HBCD were the predominant diastereoisomers in the soil of the study area.

关键词： Hexabromocyclododecane(HBCD) Temporal–spatial distribution Diastereoisomers Seasonal variation Soil

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针灸治疗溃疡性结肠炎结局指标的分析

中国针灸 2024年第10期44卷 1214-1220页

作者：叶香吟周园芳周俊吕晓松孙睿睿梁繁荣何伟重庆市江津区中医院针灸科重庆402260 成都中医药大学针灸推拿学院四川成都610075

目的:明确针灸治疗溃疡性结肠炎(UC)的关键结局指标。方法:检索中国期刊全文数据库(CNKI)、万方数据知识服务平台(Wanfang)、维普科技中文期刊数据库(VIP)、中国生物医学文献数据库(Sino Med)、Pub Med、EMbase、Cochrane Library、Web ... 详细信息

目的:明确针灸治疗溃疡性结肠炎(UC)的关键结局指标。方法:检索中国期刊全文数据库(CNKI)、万方数据知识服务平台(Wanfang)、维普科技中文期刊数据库(VIP)、中国生物医学文献数据库(Sino Med)、Pub Med、EMbase、Cochrane Library、Web of Science(WOS)数据库收录的针灸治疗UC的随机对照试验(RCT),检索时限为建库至2023年3月20日。提取文献基本信息、干预措施、结局指标相关内容,分析主、次要结局指标的设置,各类指标的使用频次、组合使用情况,并归纳针灸治疗UC的RCT指标域。结果:共纳入215个RCT,涉及结局指标54个,包括中医病证、症状/体征、理化检测、生活质量、远期预后、安全性事件6类,使用频次排前3位的依次为临床疗效评价、针灸不良反应、主要症状评分。其中仅3篇文献明确报告了主、次要结局指标,180篇文献同时使用了两类结局指标,仅3篇文献描述了观察指标多个具体评价时点,明确报告疗效评定标准参考来源的126篇文献涉及的参考标准达57个。结论:目前针灸治疗UC的RCT,结局指标未形成统一标准,主、次要结局指标有待明确,临床疗效评价标准不一,对患者生活质量、随访、安全性事件关注较少,应注重构建以客观内镜评分为主,以症状/体征改善、生化检查等为辅的结局指标集。

关键词：溃疡性结肠炎针灸随机对照试验结局指标指标域

合并微血管侵犯的HCC患者术后辅助治疗:现状与前景

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保健医学研究与实践 2024年第1期21卷 150-156页

作者：黄俊杰黄平廖锐孙锐睿曹洪祥重庆医科大学第一临床学院重庆400016 重庆医科大学附属第一医院肝胆外科重庆400016

原发性肝细胞肝癌是世界上常见的恶性肿瘤,手术切除是其首选的治疗方式,但微血管侵犯(MVI)作为其独立的危险因素影响着手术后患者的生存情况。本文介绍了术后MVI阳性对患者预后的影响,同时介绍了目前常用于预防术后复发,改善肝切除患者... 详细信息

原发性肝细胞肝癌是世界上常见的恶性肿瘤,手术切除是其首选的治疗方式,但微血管侵犯(MVI)作为其独立的危险因素影响着手术后患者的生存情况。本文介绍了术后MVI阳性对患者预后的影响,同时介绍了目前常用于预防术后复发,改善肝切除患者生存情况的一系列辅助治疗方法,包括放射疗法、肝动脉化疗栓塞术(TACE)、肝动脉灌注化疗(HAIC)、靶向疗法、免疫疗法、抗病毒及营养支持疗法,评述了各类疗法对MVI阳性患者的治疗效果。作者认为,大多数治疗均展现了相应的应用前景,但疗效和适用人群有待进一步探索,而联合治疗可能是未来术后辅助治疗前进的方向。

关键词：原发性肝癌微血管侵犯肿瘤复发术后辅助治疗

编译型软PLC的可定制高速脉冲串输出功能设计

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电子器件 2024年第2期47卷 319-325页

作者：许敬尧高露露张晓捷程广河孙瑞瑞青岛理工大学信息与控制工程学院山东青岛266500 齐鲁工业大学(山东省科学院)山东省计算中心(国家超级计算济南中心) 山东济南250014

针对高速脉冲运动控制的性能精度和软PLC高速脉冲模块的便捷调用等问题,研究并设计一种基于编译型软PLC的高速脉冲输出功能模块,研究内容包括:PTO硬件资源配置设计、PTO人机交互设计、PTO功能转译设计和PTO驱动设计。本设计方法基于语... 详细信息

针对高速脉冲运动控制的性能精度和软PLC高速脉冲模块的便捷调用等问题,研究并设计一种基于编译型软PLC的高速脉冲输出功能模块,研究内容包括:PTO硬件资源配置设计、PTO人机交互设计、PTO功能转译设计和PTO驱动设计。本设计方法基于语言转换,借用C语言灵活的编程优势,可同时设置几百个不同的目标速度,继而适用于更复杂的曲线运动控制场合。驱动设计中,采用S型曲线算法和时基转换算法,实现脉冲的平滑频率转换和宽范围的频率输出。在SK2109 PLC上进行实验验证,采用示波器和编码器回采共同监测PTO输出端口的脉冲,通过与人机交互中的参数进行对比,实验结果表明,高速脉冲串输出功能模块操作简单便捷,输出平滑精确,能够提供平滑稳定的运动控制。

关键词：编译型软PLC 高速脉冲输出 PTO S型曲线运动控制

Cerebral fractional amplitude of low-frequency fluctuations may predict headache intensity improvement following acupuncture treatment in migraine patients

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Journal of Traditional Chinese Medicine 2020年第6期40卷 1041-1051页

作者： Li Zhengjie Zhou Jun Cheng Shirui Lan Lei sun ruirui Liu Mailan Yang Jie Gao Yujie Guo Taipin Gong Qiyong Zeng Fang Liang Fanrong Acupuncture&Tuina School/The Third Teaching Hospital Chengdu University of Traditional Chinese MedicineChengdu 610000China Acupuncture&Tuina School Hunan University of Chinese MedicineChangsha 410000China Huaxi Magnetic Resonance Research Center West China Hospital of Sichuan UniversityChengdu 610000China

OBJECTIVE:To explore how baseline resting-state cerebral function predicts clinical outcomes of acupuncture treatment for ***:One hundred migraine patients and 46 healthy subjects were *** were randomized into the acupuncture,sham acupuncture,and waiting list ***-state functional magnetic resonance imaging data were collected at baseline and after 1 month of longitudinal acupuncture *** amplitude of low-frequency fluctuations(f ALFF)calculations were applied to explore the associations between baseline f ALFF and changes in clinical variables in the acupuncture treatment group and the waiting list ***:Compared with healthy subjects,migraine patients had lower f ALFF in the left rostral ventromedial medulla,right thalamus,left amygdala,and right angular *** analyses revealed that baseline f ALFF values in the left middle frontal gyrus,left superior temporal gyrus,and middle temporal gyrus were positively associated with headache intensity changes in the acupuncture treatment group,while baseline f ALFF values in the bilateral lingual gyrus and cuneus were negatively associated with headache intensity changes in this ***:The baseline f ALFF values of brain regions associated with cognitive pain modulation,but not migraine severity,may predict future headache intensity improvement levels in migraine patients receiving acupuncture treatment.

关键词： Acupuncture Migraine disorders Treatment outcome Magnetic resonance imaging

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成都老官山汉墓髹漆人像足三阴脉循行考证

成都中医药大学学报 2024年第1期47卷 31-34页

作者：程施瑞邱科孙睿睿张乙小周兴兰梁繁荣曾芳成都中医药大学四川成都611137 乐山职业技术学院四川乐山614000 广安市中医医院四川广安638001

成都老官山汉墓出土的经穴髹漆人像是迄今为止我国发现的最早、最完整的经穴人体医学模型。结合早期经脉相关文物文献及同墓穴出土的《天回医简·脉书·下经》,对老官山汉墓经穴髹漆人像足太阴脉、足厥阴脉、足少阴脉进行考证,研究其循... 详细信息

成都老官山汉墓出土的经穴髹漆人像是迄今为止我国发现的最早、最完整的经穴人体医学模型。结合早期经脉相关文物文献及同墓穴出土的《天回医简·脉书·下经》,对老官山汉墓经穴髹漆人像足太阴脉、足厥阴脉、足少阴脉进行考证,研究其循行方向及路径特点,对于研究早期经络理论的形成、发展与演变有着重要的学术价值。

关键词：成都老官山汉墓经穴髹漆人像足三阴脉经脉学说

System Development for Storm Surge Hazard Assessment Based on WebG IS for Tianjin Binhai New Area

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Transactions of Tianjin University 2016年第1期22卷 50-56页

作者：崔博周正印王晓玲孙蕊蕊孙小沛 State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin University

It is imperative to develop a risk assessment system for quickly predicting storm surge disaster due to the vulnerability of Tianjin Binhai New Area. The flood routing model with user-defined breaches was firstly estab- lished based on the seed spread algorithm in order to achieve a rapid forecasting of storm surge flood information. Furthermore, fuzzy mathematics was utilized to identify the storm disaster grade, and the hazard mapping was con- ducted to visually obtain the hazard spatial and temporal distribution. Finally, the flood routing visuaUzation method was proposed based on numerical simulation of storm surge to achieve the reappearance scene of dynamic evolution process. The developed system can play a vital role in the management and decision-making of sea dyke mitigation engineering in Tianjin Binhai New Area.

关键词： storm surge disaster hazard assessment system WebGIS Tianjin Binhai New Area

Synthesize of ZnO Nanorods on Quartz Substrates with Seed Layer via Hydrothermal Method: Influence of Solution Concentration

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Materials Sciences and Applications 2022年第12期13卷 587-594页

作者： Qiang Niu Rongjie Xue Jianfeng Su ruirui sun Haofeng Yan Hengyuan Zhang Department of Mathematics and Physics Luoyang Institute of Science and Technology Luoyang China

Vertically oriented ZnO nanorods have been synthesized by hydrothermal method on quartz substrates with a seed layer. The influence of solution concentration on the morphology, structural and optical properties was analyzed. Results indicated that with the increase of solution concentration, the diameter and uniformity of ZnO nanorods increased. And the preferred orientation is obviously which shows better crystal quality. Typically, when the solution concentration is 0.03 mol/L, the nanorods exhibit a stronger UV emission peak located around 380 nm. In the visible region, all synthesized samples demonstrate more than 80% of optical transparency.

关键词： Hydrothermal Method ZnO Nanorods Solution Concentration

YC湖区叶绿素a时空变化特征及影响因素分析

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安徽农学通报 2024年第9期30卷 77-83页

作者：谢茂嵘刘帅吕文杨文晶杨惠姜宇孙瑞瑞蔡晓钰杨金艳江苏省水文水资源勘测局苏州分局江苏苏州215011

本研究基于2021年YC湖区水质逐月监测,分析了湖区生态系统响应参数(叶绿素a)及氮、磷营养盐的时空变化特征。通过对监测数据进行多元逐步回归分析,找出与叶绿素a显著相关的环境因子,并建立多元回归方程。结果表明,湖区叶绿素a含量全年... 详细信息

本研究基于2021年YC湖区水质逐月监测,分析了湖区生态系统响应参数(叶绿素a)及氮、磷营养盐的时空变化特征。通过对监测数据进行多元逐步回归分析,找出与叶绿素a显著相关的环境因子,并建立多元回归方程。结果表明,湖区叶绿素a含量全年平均值变化范围5.80~46.96μg/L,叶绿素a、总氮和总磷含量有明显的季节性差异。湖区各监测点的水质因子含量时空差异较大,湖区西湖的叶绿素a、氨氮、总氮和总磷的距平系数分别为15.6%、51.5%、15.0%和17.5%,高于中湖和东湖,总体水质从北向南,从西向东,逐渐趋好。叶绿素a含量与水温(T)、总磷(TP)、高锰酸盐指数(CODMn)和pH呈极显著正相关,而与透明度(SD)呈极显著负相关;进一步逐步回归分析,高锰酸盐指数、总磷和水温3个因子与叶绿素a显著相关,均表现为正相关,复相关系数为0.573。

关键词：叶绿素a 时空变化特征生态系统环境因子多元逐步回归分析