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Advances in Polar Science 2024年

作者： Sergio SoTo ACU?A Alexander o.VARGAS Jonatan KALUZA Consejo Nacional de Investigaciones Científicas y Técnicas (CoNICET) Red Paleontológica U-Chile，Departamento de Biología， Facultad de Ciencias， Universidad de Chile Fundación de Historia Natural Félix de Azara， Universidad Maimónides Escuela de Geología，Facultad de Ciencias， Ingeniería y Tecnología， Universidad Mayor， Providencia

The first dinosaur discovered in the Antarctic continent was the ankylosaur Antarctopelta oliveroi in the 1980s. Nevertheless， since then several hypotheses of phylogenetical relationships have been proposed because these have been depended on how the skeletal remains have been interpreted. The main obstacle for clarifying its phylogenetic position is that many portions of the skeleton remain unknown， in addition to the presence of unknown characters in typical ankylosaurs. Considered an ankylosaurid， nodosaurid， or even a chimaera， a recent proposal based on mostly complete material of a new ankylosaur from Chilean Patagonia provided support for a novel phylogenetic hypothesis: Antarctopelta and other southern ankylosaurs are an early branching clade， the Parankylosauria， whose origin probably dates to the Late Jurassic. In the light of this new view， a redescription of the available skeletal remains is provided together with a new reconstruction of the first Antarctic dinosaur known to the science community.

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Nutritional epigenetics education improves diet and attitude of parents of children with autism or attention deficit/hyperactivity disorder

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World Journal of Psychiatry 2024年第1期14卷 159-178页

作者： Renee J Dufault Katherine M Adler David o Carpenter Steven G Gilbert Raquel A Crider College of Graduate Health Studies A.T.Still UniversityKirksvilleMO 63501United States Department of Research Food Ingredient and Health Research InstituteNaalehuHI 96772United States Department of Health Sciences University of New HavenWest HavenCT 06516United States Institute for Health and the Environment School of Public HealthState University of New YorkAlbanyNY 12222United States Department of Research Institute of Neurotoxicology and Neurological DisordersSeattleWA 98105United States Department of Statistics Food Ingredient and Health Research InstituteNaalehuHI 96772United States

BACKGRoUND Unhealthy maternal diet leads to heavy metal exposures from the consumption of ultra-processed foods that may impact gene behavior across generations,creating conditions for the neurodevelopmental disorders known as autism and attention deficit/hyperactivity disorder(ADHD).Children with these disorders have difficulty metabolizing and excreting heavy metals from their bloodstream,and the severity of their symptoms correlates with the heavy metal levels measured in their *** may play a key role in helping parents reduce their ultra-processed food and dietary heavy metal intake by providing access to effective nutritional epigenetics *** To test the efficacy of nutritional epigenetics instruction in reducing parental ultra-processed food *** The study utilized a semi-randomized test and control group pretest-posttest pilot study design with participants recruited from parents having a learning-disabled child with autism or ***-two parents who met the inclusion criteria were randomly selected to serve in the test(n=11)or control(n=11)*** test group participated in the six-week online nutritional epigenetics tutorial,while the control group did *** efficacy of the nutritional epigenetics instruction was determined by measuring changes in parent diet and attitude using data derived from an online diet survey administered to the participants during the pre and post intervention *** intake scores were derived for both ultra-processed and whole/organic *** sample t-tests were conducted to determine any differences in mean diet scores within each *** There was a significant difference in the diet scores of the test group between the pre-and post-intervention *** parents in the test group significantly reduced their intake of ultra-processed foods with a preintervention diet score of 70(mean=5.385,SD=2.534)and a post-intervention diet score of 113(mean=8.692,SD=1.750)and the

关键词： Epigenomics Parenteral nutrition Autism Attention deficit/hyperactivity disorder Ultra-processed foods Heavy metals

Hypothalamic circuits and aging:keeping the circadian clock updated

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Neural Regeneration Research 2024年第9期19卷 1919-1928页

作者： Rosa Vázquez-Lizarraga Lucia Mendoza-Viveros Carolina Cid-Castro Sareni Ruiz-Montoya Erick Carreño-Vázquez Ricardo orozco-Solis Instituto Nacional de Medicina Genómica(INMEGEN) México CityMéxico Centro de Investigacíon sobre el Envejecimiento Centro de Investigacíon y de Estudios Avanzados(CIE-CINVESTAV)México CityMéxico Instituto de Investigaciones Biomédicas Universidad Nacional Autónoma de México UNAMMéxico CityMéxico

over the past century,age-related diseases,such as cancer,type-2 diabetes,obesity,and mental illness,have shown a significant increase,negatively impacting overall quality of *** on aged animal models have unveiled a progressive discoordination at multiple regulatory levels,including transcriptional,translational,and post-translational processes,resulting from cellular stress and circadian *** circadian clock emerges as a key regulator,sustaining physiological homeostasis and promoting healthy aging through timely molecular coordination of pivotal cellular processes,such as stem-cell function,cellular stress responses,and inter-tissue communication,which become disrupted during *** the crucial role of hypothalamic circuits in regulating organismal physiology,metabolic control,sleep homeostasis,and circadian rhythms,and their dependence on these processes,strategies aimed at enhancing hypothalamic and circadian function,including pharmacological and non-pharmacological approaches,offer systemic benefits for healthy *** brain-directed drug administration represents a promising avenue for effectively targeting specific brain regions,like the hypothalamus,while reducing side effects associated with systemic drug delivery,thereby presenting new therapeutic possibilities for diverse age-related conditions.

关键词： aging astrocytes cellular stress responses circadian clock hypothalamus intranasal drug administration metabolic control nutrient sensor SIRT1 sleep homeostasis

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Temperature Trends and Accumulation of Chill Hours, Chill Units, and Chill Portions in South Carolina

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Atmospheric and Climate Sciences 2024年第2期14卷 173-190页

作者： José o. Payero Edisto Research and Education Center Clemson University Blackville SC USA Department of Agricultural Sciences Clemson University Clemson SC USA

There is considerable concern about the potential impact of climate change on agriculture, such as the accumulation of chilling hours needed to break the dormancy of many perennial plants, like fruit trees. Therefore, this study aimed to determine if there had been a significant change in air temperatures and chill hours, chill units, and chill portion accumulation in South Carolina over the last two decades. Two decades of daily maximum (Tmax) and minimum (Tmin) air temperature records were obtained from weather stations in thirty-one counties in South Carolina. Hourly temperature data, reconstructed from the daily data, were used to calculate the daily and annual chill hours, chill units, and chill portions accumulation using four different chill models for each location and year. The chill models included the T(t) °C model, the 0°C °C model, the Utah model, and the Dynamic model. For each county, regression analyses were conducted to evaluate the historical trends. Despite year-to-year variability, the tendency was a statistically significant (α = 0.05) increase in air temperature, averaging 0.089°C per year for 20 out of 31 counties in South Carolina. The other 11 counties had no significant change in temperature. The average temperature increase in the 31 counties was 0.072°C per year. The temperature increase resulted in a decrease in annual chill accumulation during the fall to spring, averaging 17.7 chill hours, 8.6 chill hours, 17.0 chill units, and 0.40 chill portions per year calculated with the T(t) °C, 0°C °C, Utah, and Dynamic models, respectively. However, whether this decrease in chill values was statistically significant or not depended on the chill model used. This study did not investigate the cause of the observed historical trends in temperature and chill accumulation. Still, if the trends continue, they could significantly impact the future of the temperate fruit tree industry in the state.

关键词： Chill Hours Chill Units Chill Portions Temperature Fruit Trees Climate Change Dormancy

A Procedure for Trisecting an Acute Angle (Method 2)

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Advances in Pure Mathematics 2024年第4期14卷 204-213页

作者： Lyndon o. Barton Department of Math and Physics Delaware State University Dover USA

This paper presents an alternate graphical procedure (Method 2), to that presented in earlier publications entitled, “A Procedure for Trisecting an Acute Angle” and “A Key to Solving the Angle Trisection Problem”. The procedure, when applied to the 30˚ and 60˚ angles that have been “proven” to be nottrisectable and the 45˚ benchmark angle that is known to be trisectable, in each case produced a construction having an identical angular relationship with Archimedes’ Construction, as in Section 2 on THEoRY of this paper, where the required trisection angle was found to be one-third of its respective angle (i.e. DE’MA = 1/3 DE’CG). For example, the trisection angle for the 30˚, 45˚ and 60˚ angles were 10.00000˚, 15.00000˚, and 20.00000˚, respectively, and Section 5 on PRooF in this paper. Therefore, based on this identical angular relationship and the numerical results (i.e. to five decimal places), which represent the highest degree of accuracy and precision attainable by The Geometer’s Sketch Pad software, one can only conclude that not only the geometric requirements for arriving at an exact trisection of the 30˚ and 60˚ angle (which have been “proven” to be not-trisectable) have been met, but also, the construction is valid for any arbitrary acute angle, despite theoretical proofs to the contrary by Wantzel, Dudley, and others.

关键词： Archimedes’ Construction College Geometry College Mathematics Angle Trisection Famous Problems in Mathematics Mechanism Analysis Geometer’s Sketch Pad

Evidence of the Great Attractor and Great Repeller from Artificial Neural Network Imputation of Sloan Digital Sky Survey

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Journal of High Energy Physics, Gravitation and Cosmology 2024年第3期10卷 1178-1194页

作者： Christopher Cillian o’Neill School of Computing Ulster University Belfast UK Data Analysis CCT Dublin Ireland

The Sloane Digital Sky Survey (SDSS) has been in the process of creating a 3D digital map of the Universe, since 2000AD. However, it has not been able to map that portion of the sky which is occluded by the dust gas and stars of our own Milkyway Galaxy. This research builds on work from a previous paper that sought to impute this missing galactic information using Inpainting, polar transforms and Linear Regression ANNs. In that paper, the author only attempted to impute the data in the Northern hemisphere using the ANN model, which subsequently confirmed the existence of the Great Attractor and the homogeneity of the Universe. In this paper, the author has imputed the Southern Hemisphere and discovered a region that is mostly devoid of stars. Since this area appears to be the counterpart to the Great Attractor, the author refers to it as the Great Repeller and postulates that it is an area of physical repulsion, inline with the work of GerdPommerenke and others. Finally, the paper investigates large scale structures in the imputed galaxies.

关键词： Artificial Neural Networks Convolutional Neural Networks SDSS Anisotropies Great Attractor

Actionable Genotypes and Their Association with Life Span in Iceland

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四川生理科学杂志 2024年第4期46卷 208-208页

作者： Brynjar o Jensson From deCoDE Genetics-Amgen (B.o.J. G.A.A. H.K. R.F. H. Helgason A.O. G.S. H.P.E. G.H.H. B.A.A. H.J. G.R.O. A. Sturluson S.A.G. G.A.T. F.Z. K.H.S.M. G.P. A. Sigurdsson Adalbjorg Jonasdottir Aslaug Jonasdottir M.K.M. A. Helgadottir V.S. J.G. S.N.S. D.O.A. J.S. O.T.M. G.M. B.V.H. A. Helgason H.S. I.J. H. Holm T.R. U.T. D.F.G. K.S. P.S.) the Faculty of Medicine School of Health Sciences (G.A.A. M.K.M. R.H. D.O.A. I.J. U.T. K.S.) the Department of Anthropology (K.H.S.M. A. Helgason) and the School of Engineering and Natural Sciences (H. Helgason G.H.H. D.F.G.) University of Iceland the Departments of Urology (R.H.) Clinical Biochemistry (I.O.) Oncology (O.T.J.) Medicine (D.O.A.) and Immunology (I.J.) Landspitali-the National University Hospital of Iceland and the School of Science and Engineering Reykjavik University (B.V.H.) - all in Reykjavik Iceland.

Background:In 2021,the American College of Medical Genetics and Genomics(ACMG)recommended reporting actionable genotypes in 73 genes associated with diseases for which preventive or therapeutic measures are *** of the... 详细信息

关键词： College action Ice

Applying a Context-based Method to Build a Knowledge Graph for the Blue Amazon

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Data Intelligence 2024年第1期6卷 64-103页

作者： Pedro de Moraes Ligabue Anarosa Alves Franco Brandão Sarajane Marques Peres Fabio Gagliardi Cozman Paulo Pirozelli Escola Politécnica Universidade de São PauloRua Visconde da Luz60São PauloSão Paulo 05508-010Brazi Escola Politécnica Universidade de São PauloAv.Prof.Luciano Gualbertotv 3158São Paulo 05508-010Brazil Escola de Artes Ciências e Humanidades Universidade de São PauloRua Arlindo Béttio1000São Paulo 03828-000Brazil Instituto de Estudos Avançados Universidade de São PauloRua da Praça do Relógio109São Paulo 05508-050Brazil

Knowledge graphs are employed in several tasks,such as question answering and recommendation systems,due to their ability to represent relationships between *** constructing such a graphs,however,remains an unresolved challenge within knowledge *** tackle this challenge,we propose CtxKG,a method specifically aimed at extracting knowledge graphs in a context of limited resources in which the only input is a set of unstructured text *** is based on openIE(a relationship triple extraction method)and BERT(a language model)and contains four stages:the extraction of relationship triples directly from text;the identification of synonyms across triples;the merging of similar entities;and the building of bridges between knowledge graphs of different *** method distinguishes itself from those in the current literature(i)through its use of the parse tree to avoid the overlapping entities produced by base implementations of openIE;and(ii)through its bridges,which create a connected network of graphs,overcoming a limitation similar methods have of one isolated graph per *** compare our method to two others by generating graphs for movie articles from Wikipedia and contrasting them with benchmark graphs built from the oMDb movie *** results suggest that our method is able to improve multiple aspects of knowledge graph *** also highlight the critical role that triple identification and named-entity recognition have in improving the quality of automatically generated graphs,suggesting future paths for ***,we apply CtxKG to build BlabKG,a knowledge graph for the Blue Amazon,and discuss possible improvements.

关键词： knowledge graph word embeddings relationship triple extraction Blue Amazon Atlantic ocean Brazilian coast

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Influence of railway wheel tread damage on wheel-rail impact loads and the durability of wheelsets

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Railway Engineering Science 2024年第1期32卷 20-35页

作者： Michele Maglio Tore Vernersson Jens C.o.Nielsen Anders Ekberg Elena Kabo CHARMEC Department of Mechanical and Maritime SciencesChalmers University of TechnologySE‑41296 GothenburgSweden

Dynamic wheel-rail contact forces induced by a severe form of wheel tread damage have been measured by a wheel impact load detector during full-scale field tests at different vehicle *** on laser scanning,the measured three-dimensional damage geometry is employed in simulations of dynamic vehicle-track interaction to calibrate and verify a simulation *** relation between the magnitude of the impact load and various operational parameters,such as vehicle speed,lateral position of wheel-rail contact,track stiffness and position of impact within a sleeper bay,is *** calibrated model is later employed in simulations featuring other forms of tread damage;their effects on impact load and subsequent fatigue impact on bearings,wheel webs and subsurface initiated rolling contact fatigue of the wheel tread are *** results quantify the effects of wheel tread defects and are valuable in a shift towards condition-based maintenance of running gear,and for general assessment of the severity of different types of railway wheel tread damage.

关键词： Wheel tread damage Rolling contact fatigue cluster Field measurements Dynamic vehicle-track interaction Wheel-rail impact load Wheelset durability

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Low-Cost and Biodegradable Thermoelectric Devices Based on van der Waals Semiconductors on Paper Substrates

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Energy & Environmental Materials 2024年第1期7卷 205-210页

作者： Gulsum Ersu Carmen Munuera Federico J.Mompean Daniel Vaquero Jorge Quereda Jo?o Elias F.S.Rodrigues Jose A.Alonso Eduardo Flores Jose R.Ares Isabel J.Ferrer Abdullah M.Al-Enizi Ayman Nafady Sruthi Kuriakose Joshua o.Island Andres Castellanos-Gomez Materials Science Factory Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC) Nanotechnology Group USAL–Nanolab Univesidad de Salamanca GISC Departamento de Física de Materiales Universidad Complutense de Madrid Departamento de Física Aplicada Centro de Investigación y Estudios Avanzados MIRE Group Departamento de Física de Materiales Universidad Autónoma de Madrid Instituto Nicolás Cabrera Universidad Autónoma de Madrid Department of Chemistry College of Science King Saud University Department of Physics and Astronomy University of Nevada Las Vegas

We present a method to fabricate handcrafted thermoelectric devices on standard office paper *** devices are based on thin films of WS2,Te,and BP（P-type semiconductors） and TiS3and TiS2（N-type semiconductors）,depo... 详细信息

关键词： paper-based electronics Seebeck effect semiconductors thermoelectrics van der Waals materials