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Development and validation of tongue imaging-based radiomics tool for the diagnosis of insomnia degree:a two-center study

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Medical Data Mining 2024年第1期7卷 24-31页

作者： rui Ye Ze-Kun Jiang Rong Shao Qian Yan Li-Juan Zhou ting-rui zhang Ying-Chun Sun Department of Gynecology Qingdao Hiser Hospital Affiliated of Qingdao University(Qingdao Traditional Chinese Medicine Hospital)Qingdao 266000China Department of Traditional Chinese Medicine Jiaozhou Traditional Chinese Medicine HospitalQingdao 266000China College of Computer Science Sichuan UniversityChengdu 610000China Adult Traditional Chinese Medicine Department Qingdao Women and Children’s HospitalQingdao 266000China College of Traditional Chinese Medicine Shandong University of Traditional Chinese MedicineJinan 250000China Sichuan University-Pittsburgh Institute Sichuan UniversityChengdu 610000China.

Background:Traditional Chinese medicine(TCM)is commonly used for the diagnosis and treatment of insomnia,with tongue diagnosis being particularly *** aim of our study was to develop and validate a novel tongue imaging-based radiomics(TIR)method for accurately diagnosing insomnia ***:This two-center analysis prospectively enrolled 399 patients who underwent tongue imaging between July and October 2021 and divided them into primary and validation cohorts by study ***,we referred to the Insomnia Severity Index(ISI)standard and the degree of insomnia was evaluated as absent,subthreshold,moderate,or *** developed the TIR diagnostic tool,a U-Net algorithm was used to segment tongue ***,seven imaging features were selected from the extracted high-throughout radiomics features using the least absolute shrinkage and selection operator ***,the final radiomics model was developed in the primary cohort and tested in the independent validation ***,we assessed and compared the diagnostic performance differences between TCM tongue diagnosis and our TIR diagnostic tool with the ISI gold *** confusion matrix was calculated to evaluate the diagnostic ***:Seven tongue imaging features were selected to build the TIR tool,with showing good correlations with the insomnia *** TIR method had an accuracy of 0.798,a macro-average sensitivity of 0.78,a macro-average specificity of 0.906,a weighted-average sensitivity of 0.798,and a weighted specificity of 0.916,showing a significantly better performance compared to the average performance of three experienced TCM physicians(mean accuracy of 0.458,P<0.01).Conclusions:The preliminary study demonstrates the potential application of TIR in the diagnosis of insomnia degree and measurement of sleep *** integration of quantitative imaging analysis and machine learning algorithms holds promise for advancing both of TCM and precision slee

关键词： insomnia tongue image radiomics machine learning traditional Chinese medicine

Enrichment and reconfiguration of titanium-bearing phase in vortex smelting reduction process of vanadium-titanium magnetite

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Journal of Iron and Steel Research International 2024年第7期31卷 1582-1589页

作者： Yong-chao Han Zhi-he Dou rui zhang ting-an zhang Shuai Fang Key Laboratory for Ecological Metallurgy of Multimetallic Ores(Ministry of Education) Shenyang 110819LiaoningChina School of Metallurgy Northeastern UniversityShenyang 110819LiaoningChina

To comprehensively utilize the low-iron high-vanadium-titanium magnetite,a new method of vortex smelting reduction of vanadium-titanium magnetite was proposed,and the enrichment and reconstitution regularity of Ti-bearing phases in the slag was investigated through X-ray fluorescence spectrometry,X-ray photoelectron spectroscopy,X-ray diffraction analysis,and optical *** phase diagram revealed that the preferential crystallization of MgTi_(2)O_(5) can be achieved by adjusting the CaO,MgO,and TiO_(2) contents of *** predominant Ti-bearing phases in the slag obtained from the reduction process are MgxTi_(3_x)O_(5)(0≤x≤1)and CaTiO_(3).FeTiO_(3) is present at carbon-iron ratio(CR)=1.3,while MgTi_(2)O4 and TiC are formed at CR=*** enrichment of TiO_(2) in the slag increases first and then decreases as the CR increases,and at CR=1.1,the enrichment of TiO_(2) in the slag reaches 51.3 wt.%.Additionally,the concentrations of MgxTi_(3_x)O_(5)(0≤x≤1)and CaTiO_(3) in the slag,along with the grain width of MgxTi_(3_x)O_(5)(0≤x≤1),decrease with the increase in CR.

关键词： Vanadium-titanium magnetite Vortex smelting reduction Phase reconfiguration TiO_(2)enrichment

Snap-through behaviors and nonlinear vibrations of a bistable composite laminated cantilever shell:an experimental and numerical study

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Applied Mathematics and Mechanics(English Edition) 2024年第5期45卷 779-794页

作者： Lele REN Wei zhang ting DONG Yufei zhang State Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong UniversityShanghai 200240China Department of Mechanics Guangxi UniversityNanning 530004China Beijing Key Laboratory of Nonlinear Vibrations and Strength of Mechanical Structures College of Mechanical EngineeringBeijing University of TechnologyBeijing 100124China School of Mechanical Engineering Beijing Institute of TechnologyBeijing 100081China

The snap-through behaviors and nonlinear vibrations are investigated for a bistable composite laminated cantilever shell subjected to transversal foundation excitation based on experimental and theoretical *** improved experimental specimen is designed in order to satisfy the cantilever support boundary condition,which is composed of an asymmetric region and a symmetric *** symmetric region of the experimental specimen is entirely clamped,which is rigidly connected to an electromagnetic shaker,while the asymmetric region remains free of *** motion paths are realized for the bistable cantilever shell by changing the input signal levels of the electromagnetic shaker,and the displacement responses of the shell are collected by the laser displacement *** numerical simulation is conducted based on the established theoretical model of the bistable composite laminated cantilever shell,and an off-axis three-dimensional dynamic snap-through domain is *** numerical solutions are in good agreement with the experimental *** nonlinear stiffness characteristics,dynamic snap-through domain,and chaos and bifurcation behaviors of the shell are quantitatively *** to the asymmetry of the boundary condition and the shell,the upper stable-state of the shell exhibits an obvious soft spring stiffness characteristic,and the lower stable-state shows a linear stiffness characteristic of the shell.

关键词： bistable composite laminated cantilever shell snap-through behavior nonlinear vibration nonlinear stiffness characteristic chaos and bifurcation

RNA m6A dynamic modification mediated by nucleuslocalized FTO is involved in follicular reserve

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Zoological Research 2024年第2期45卷 415-428页

作者： Jiao-Na zhang rui-ting Wang Francesca-Gioia Klinger Shun-Feng Cheng Wei Shen Xiao-Feng Sun College of Life Sciences Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of ShandongQingdao Agricultural UniversityQingdaoShandong 266109China Department of Biomedicine and Prevention University of Rome Tor VergataRome 00133Italy

In eukaryotic organisms,the most common internal modification of messenger RNA(m RNA)is N6-methyladenosine(m6A).This modification can be dynamically and reversibly controlled by specific enzymes known as m6A writers and *** fat-mass and obesity-associated protein(FTO)catalyzes RNA demethylation and plays a critical role in various physiological and pathological *** research identified dynamic alterations in both m6A and FTO during the assembly of primordial follicles,with an inverse relationship observed for m6A levels and nuclear-localized FTO *** of Fto small interfering RNA(si RNA)altered the expression of genes related to cell proliferation,hormone regulation,and cell chemotaxis,and affected RNA alternative *** of the full-length Fto gene led to changes in m6A levels,alternative splicing of Cdk5,cell proliferation,cell cycle progression,and proportion of primordial ***,overexpression of Fto lacking a nuclear localization signal(NLS)did not significantly alter m6A levels or primordial follicle *** findings suggest that FTO,localized in the nucleus but not in the cytoplasm,regulates RNA m6A demethylation and plays a role in cell proliferation,cell cycle progression,and primordial follicle *** results highlight the potential of m6A and its eraser FTO as possible biomarkers and therapeutic targets.

关键词： m6A FTO Ovary Primordial follicle assembly Alternative splicing

Combustion characteristics of millimeter-sized aluminum particles in fluidized bed under various O_(2)/CO_(2)/H_(2)O atmospheres Author links open overlay panel

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Particuology 2024年第8期91卷 315-322页

作者： Jialing Zhou rui zhang Dong Liu Key Laboratory of Thermal Control of Electronic Equipment Ministry of Industry and Information TechnologyNanjing210094China Advanced Combustion Laboratory School of Energy and Power EngineeringNanjing University of Science and TechnologyNanjing210094China

Aluminum is an attractive alternative fuel,but it burns very inefficiently due to the formation of a dense Al_(2)O_(3)layer which prevents O_(2)from diffusion to the surface of Al *** previous experiments,the combustion of millimeter-sized Al(mAl)particles in the fluidized bed has achieved a substantial increase in the combustion efficiency,but further improvements are still *** this study,the effects of reaction atmosphere on the fluidized combustion of mAl particles were *** experiments with different O_(2)/H_(2)O/CO_(2)concentrations were *** experimental results indicate that the combustion efficiency of mAl particles in fluidized bed increases as the mole fraction of O_(2),H_(2)O or CO_(2)increases,and the highest combustion efficiency can reach 38.7%.After the analysis of the oxide film on the surface of aluminum particles,it was found that it is easier to generate the unstableθ-Al_(2)O_(3)under CO_(2)atmosphere,and it is easier to generate the unstableγ-Al_(2)O_(3)andθ-Al_(2)O_(3)under H_(2)O *** unstable Al_(2)O_(3)film is more likely to be abraded in the fluidized bed,which leads to the effective improvement of the combustion efficiency.

关键词： Al combustion Fluidized bed Atmosphere Combustion efficiency

Passive neutron multiplicity device for^(240)Pu measurement based on FPGA

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Nuclear Science and Techniques 2024年第9期35卷 141-154页

作者： Yan zhang Hao-Ran zhang Ren-Bo Wang Ming-Yu Li rui Chen Hai-Tao Wang Xiang-ting Meng Shu-Min Zhou Bin Tang Fundamental Science on Radioactive Geology and Exploration Technology Laboratory East China University of TechnologyNanchang 330013China Engineering Research Center for Nuclear Technology Application Ministry of EducationEast China University of TechnologyNanchang 330013China Pan China Detect Technology Co.Ltd. Nanchang 330013China

A passive neutron multiplicity measurement device,FH-NCM/S1,based on field-programmable gate arrays(FPGAs),is developed specifically for measuring the mass of plutonium-240(^(240)Pu)in mixed oxide ***-NCM/S1 adopts an inte-grated approach,combining the shift register analysis mode with the pulse-position timestamp mode using an *** optimal effective length of the^(3)He neutron detector was determined to be 30 cm,and the thickness of the graphite reflector was ascertained to be 15 cm through MCNP *** fabricating the device,calibration measurements were per-formed using a^(252)Cf neutron source;a detection efficiency of 43.07%and detector die-away time of 55.79μs were *** samples of plutonium oxide were measured under identical conditions using the FH-NCM/S1 in shift register analysis mode and a plutonium waste multiplicity *** obtained double rates underwent corrections for detection efficiency(ε)and double gate fraction(f_(d)),resulting in corrected double rates(D_(c)),which were used to validate the accuracy of the shift register analysis ***,the device exhibited fluctuations in the measurement results,and within a single 20 s measurement,these fluctuations remained below 10%.After 30 cycles,the relative error in the mass of^(240)Pu was less than 5%.Finally,correlation calculations confirmed the robust consistency of both measurement *** study holds specific significance for the subsequent design and development of neutron multiplicity devices.

关键词： Spent fuel Non-destructive assay Neutron multiplicity ^(240)Pu FPGA

Fully distributed dynamic event-triggered formation-containment tracking for multiagent systems with multiple types of disturbances

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Science China(Information Sciences) 2024年第1期67卷 168-186页

作者： Weihua LI Huaguang zhang Juan zhang rui WANG College of Information Science and Engineering Northeastern University State Key Laboratory of Synthetical Automation for Process Industries Northeastern University

This paper is dedicated to addressing the time-varying output formation-containment tracking(TVOFCT) problem for heterogeneous linear multiagent systems(MASs) with multiple types of disturbances under directed communication *** agents are divided into tracking leaders,formation leaders,and *** the output space,the formation leaders are required to form an expected geometric formation while tracking the tracking leader,and the followers are required to enter the convex hull spanned by formation ***,a disturbance observer is designed to observe the disturbance with deterministic ***,by combining adaptive technology with event-triggered technology,an independent fully distributed dynamic event-triggered(FDDET) compensator is designed to estimate the state of the tracking *** main advantages of this compensator lie in the following three aspects:(1) the adaptive weight does not increase unboundedly;(2) the interval time between events is expanded;(3) the design does not rely on any global *** to the design of this compensator,an independent FDDET convex hull observer is further designed to observe the convex hull spanned by formation ***,based on the designed disturbance observer,compensator,and convex hull observer,the adaptive disturbance rejection control input which can make the MASs achieve TVOFCT is ***,a numerical simulation is provided to clearly verify the validity of the theoretical results.

关键词： formation-containment tracking disturbance rejection multiagent systems fully distributed control dynamic event-triggered control

Changes in extreme high temperature warning indicators over China under different global warming levels

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Science China Earth Sciences 2024年第6期67卷 1895-1909页

作者： Yuxia zhang Ying SUN ting HU Chinese Academy of Meteorological Sciences Beijing 100081China National Climate Center Laboratory for Climate StudiesChina Meteorological AdministrationBeijing 100081China

High temperature warning indicators play a pivotal role in meteorological departments,serving as crucial criteria for issuing warnings that guide both social production and daily *** their importance,limited studies have explored the relationship between different global warming levels and changes in high temperature warning *** this study,we analyze data from 2,419 meteorological stations over China and utilize the Coupled Model Intercomparison Project Phase 6(CMIP6)models to examine historical changes in high temperature warning indicators used by the China Meteorological *** evaluate model performance and estimate future changes in these indicators using an annual cycle bias correction *** results indicate that since 1961,the number of high temperature days(TX35d and TX40d)and length of season(TX40d and TX40l)with daily maximum temperature reaching or exceeding 35℃ and 40℃ have increased over *** intensity of high temperatures(TXx)has strengthened and the geographical extent affected by high temperatures has *** 2022,the occurrence of 40℃ high temperatures surges,with Eastern China experiencing a two-day increase in TX40d and an extended seasonal length in TX40l by over five *** CMIP6 models have underestimated the high temperature indictors associated with 35℃ during historical periods,notable difference is not observed between the models and observations for TX40d and TX40l,given their rare ***,future projections,after bias correction,indicate that the increasing trends for 35℃ and 40℃ high temperature days and length of season become more pronounced than the raw projection,suggesting a more severe increase than that anticipated *** global warming intensifies,the high temperature days and length of season are projected to increase non-linearly,while the intensity of high temperatures is expected to increase *** every 1℃ increase in global temperature,the intensity is

关键词： Extreme high temperatures Meteorological warning CMIP6 Global warming levels Future projection

Recent advances in Fe-N-C-and Co-N-C-based materials as bifunctional electrocatalysts for oxygen reduction and oxygen evolution

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Science China Chemistry 2024年第4期67卷 1137-1160页

作者： Hui-Min Xu Hong-rui Zhu Chen-Jin Huang Zhi-Jie zhang ting-Yu Shuai Qi-Ni Zhan Gao-Ren Li College of Materials Science and Engineering Sichuan UniversityChengdu 610065China

Fe-nitrogen-carbon(Fe-N-C)-and Co-nitrogen-carbon(Co-N-C)-based electrocatalysts have been widely concerned because of their high OER/ORR activity,low metal cost,and simple *** exploration of Fe-N-C and Co-N-C single atombased catalysts with high activity and stability to overcome the slow kinetics of oxygen reduction and oxygen evolution reactions is also the key to the development of efficient electrolytic water,fuel cells,and rechargeable metal-air ***-N-C and Co-N-C single atom-based electrocatalysts have the advantages of a high utilization rate of metal atoms and high electrocatalytic activity,and are ideal catalysts for promoting electrochemical energy conversion and *** general principles of designing Fe-N-C and Co-N-C single atom-based electrocatalysts are reviewed in this ***,the strategies to improve the bifunctional catalytic activity and stability are ***,the challenges and prospects of Fe-N-C and Co-N-C single atom-based catalysts are well *** review will provide a reference for the directed optimization of Fe-N-C and Co-N-C single atom-based catalysts.

关键词： Fe-N-C Co-N-C single atom bifunctional oxygen electrocatalysts