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Prevalence and characteristics of MAFLD in Chinese adults aged 40 years or older:A community-based study

Hepatobiliary & Pancreatic Diseases International 2022年第2期21卷 154-161页

作者： Jing Zeng Li Qin Qian Jin rui-Xu Yang Guang Ning qing Su Zhen Yang Jian-Gao fan Department of Gastroenterology Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai 200092China Department of Endocrinology Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai 200092China Department of Endocrine and Metabolic Diseases Shanghai Institute of Endocrinology and MetabolismShanghai Clinical Center for Endocrine and Metabolic DiseasesRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China

Background: Nonalcoholic fatty liver disease(NAFLD) was recently proposed to be renamed metabolic dysfunction-associated fatty liver disease(MAFLD) with the diagnostic criteria revised. We investigated the similarities and differences in the prevalence and clinical characteristics of MAFLD and NAFLD in Chinese adults. Methods: A cross-sectional study of 9980 Chinese individuals aged 40 years or older was performed between 2011 and 2012 using randomized, stratifed cluster sampling in Shanghai, China. A detailed questionnaire and the results of abdominal ultrasonography, a standardized 2-h 75-g oral glucose tolerance test and blood biochemical examinations were collected. Results: A total of 9927 subjects were included in this study. The prevalence of MAFLD(40.3%) was significantly higher than that of NAFLD(36.9%)( P < 0.05). MAFLD was highly prevalent in type 2 diabetes mellitus(T2DM)(53.8%), impaired fasting glucose(35.7%) and impaired glucose tolerance(40.9%). High risk of advanced fbrosis based on fbrosis-4 was highly prevalent(14.7%) in lean MAFLD with T2DM. Among 9927 subjects, 3481(35.1%) fulflled the diagnostic criteria for MAFLD and NAFLD(MAFLD + NAFLD +), 521(5.2%) MAFLD + NAFLD-, and 181(1.8%) MAFLD-NAFLD +. The MAFLD + NAFLD-group had more signifcant metabolic disorders than those in the MAFLD + NAFLD + group(all P < 0.05). Among MAFLD-NAFLD + subjects, 82.9% had metabolic disorders. Conclusions: The new defnition of MAFLD may better reflect the pathogenesis related to metabolism. Future research should focus on studying the natural history, pathogenesis and treatment effectivity of the overlap and non-overlap of NAFLD and MAFLD subjects.

关键词： Nonalcoholic fatty liver disease Metabolic dysfunction-associated fatty liver disease Prevalence Oral glucose tolerance test

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MXene基水凝胶在创面修复领域的应用

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中国组织工程研究 2025年第16期29卷 3486-3493页

作者：何蕊李重一王瑞瑶曾丹范代娣西北大学化工学院陕西省可降解生物医用材料重点实验室陕西省生物材料与发酵工程技术研究中心陕西省西安市710127

背景:MXene基水凝胶是一类纳米复合的多功能性水凝胶材料,在慢性创面(如糖尿病足、压疮、癌症及外伤性溃疡等)修复领域有广阔的应用前景。目的:综述MXene基水凝胶的优势及其在创面修复领域的应用和相关作用机制。方法:检索中国知网、维... 详细信息

背景:MXene基水凝胶是一类纳米复合的多功能性水凝胶材料,在慢性创面(如糖尿病足、压疮、癌症及外伤性溃疡等)修复领域有广阔的应用前景。目的:综述MXene基水凝胶的优势及其在创面修复领域的应用和相关作用机制。方法:检索中国知网、维普、PubMed、Science Direct数据库中收录的文章,文献检索时限为2010年1月至2023年10月,中文检索关键词为“MXene,水凝胶,组织工程应用,创面修复”,英文检索关键词为“MXene,Hydrogel,Wound repair”,最终选取符合标准的70篇文献进行综述。结果与结论:MXene基水凝胶在创面组织工程应用中具有优异的力学、导电和光热性能及生物相容性和抗菌性等生物学功效,可以与其他有机物质和无机物质相结合,在水凝胶中产生更大的治疗作用。含有MXene的水凝胶可以结合创面监测、药物递送和缓释以及光热治疗等方式应用于皮肤创面。尽管MXene基水凝胶复合材料的设计和制备已经取得一些良好进展,但仍处于基础研究阶段,缺乏临床验证其功效性和安全性,具有很大发展潜力和应用空间。

关键词：纳米功能材料 MXene 水凝胶创面修复生物相容性创面监测药物缓释

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Simulation of the Dendrite Morphology and Microsegregation in Solidification of Al–Cu–Mg Aluminum Alloys

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Acta Metallurgica Sinica(English Letters) 2015年第2期28卷 173-181页

作者： rui Chen qing-Yan Xu Bai-Cheng Liu Key Laboratory for Advanced Materials Processing Technology Ministry of Education School of Materials Science and Engineering Tsinghua University

Since most typical alloys in industrial applications are multicomponent with three or more components, and various CA models proposed in the past mainly focus on the binary alloys, a two-dimensional modified cellular automaton model allowing for the quantitatively predicting dendrite growth of multicomponent alloys in the low P6clet number regime is presented. The elimination of the mesh-induced anisotropy is achieved by adopting a modified virtual front tracking method. A new efficient method based on the lever rule is applied to calculate the solid fraction increment of the interfacial cells. The thermodynamic data such as liquidus temperature, the partition coefficients, and the slope of liquidus surface, needed for determining the dynamics of dendrite growth, are obtained by coupling with PanEngine. This model is applied to simulate the dendrite morphology and microsegregation of A1-Cu-Mg temary alloy both for single and multi- dendrites growth. The simulated results demonstrate that the difference of the concentration distribution profiles ahead of the dendrite tip for each alloying element mainly results from the different partition coefficients and solute diffusion coefficients. Comparison with the prediction of analytical model is carded out and it reveals the correctness of the model. Consequently, the difference in interdendritic microsegregation behavior of different components is analyzed.

关键词： Cellular automaton Multicomponent Dendrite growth Microsegregation

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First principles study on lattice vibration and electrical properties of layered perovskite Sr_2M_2O_7(M=Nb, Ta)

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Chinese Physics B 2018年第8期27卷 406-414页

作者： Xing Liu Hui-qing fan State Key Laboratory of Solidification Processing School of Materials Science and Engineering Northwestern Polytechnical University.Xi＇an 710072 China

In this paper, we performed calculations to investigate the dielectric, piezoelectric properties, Born effective charge （BEC）, and spontaneous polarization of Sr2M207, the method used in our study was a well-known density functional theory based on first-principles. The optimized results were in good agreement with previous experiments and calculations. which indicates that our calculated method is reasonable. The research we have done suggested that greater piezoelectric components of Sr2Nb207 were e31 and e33, and the contributions were derived from the A I. By studying the Born effective charge, it could be seen that the valence of ions changed, and the O of Sr2Nb207 were most obviously that caused by the covalent character of ions and the hybridization of O-2p and Nb-4d. The spontaneous polarization of Sr2Nb2O7 in the [001 ] direction is 25 p_C/cm2, while for Sr2Ta2O7, there was no spontaneous polarization in the paraelectric state. Finally, the effect of pressure on the piezoelectric properties were also investigated, the polarization of Sr2Nb2O7 decreased linearly with the increase alter pressure. All our preliminary results throw light on the nature of dielectric, piezoelectric properties, Born effective charge, and spontaneous polarization of Sr2M2OT, it was helpful for experimental research, the development of new materials, and future applications.

关键词： Sr2M2O7, first-principles dielectric and piezoelectric properties Born effective charge sponta-neous polarization

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Chronic hepatitis B virus infection： epidemiology, prevention, and treatment in China

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Frontiers of Medicine 2014年第2期8卷 135-144页

作者： rui Yu Rong fan Jinlin Hou Hepatology Unit and Department of Infectious Diseases Nanfang Hospital Southern Medical University Guangzhou 510515 China

Chronic hepatitis B is a major health problem in China. The universal vaccination program since 1992 has changed the epidemiology of hepatitis B virus infection in China from highly to moderately endemic. The most prevalent hepatitis B virus strains in China are genotypes B and C, whereas those in western provinces are genotypes D and C/D hybrid. Chronic hepatitis B poses a heavy burden to the society in China. Different treatment strategies have been explored to improve patient outcomes in a cost-effective manner. However, antiviral drugs with a low genetic barrier to resistance are still extensively used because of the generally low income and limited resources in China. Individualized antiviral therapy is closely associated with translational medicine, which utilizes information from studies on genomics, immune biomarkers, and fibrosis. The results of these studies are crucial in further improving treatment outcomes.

关键词： chronic hepatitis B epidemiology prevention treatment

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Power system restoration:a literature review from 2006 to 2016

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Journal of Modern Power Systems and Clean Energy 2016年第3期4卷 332-341页

作者： Yutian LIU rui fan Vladimir TERZIJA Key Laboratory of Power System Intelligent Dispatch and Control of Ministry of Education Shandong UniversityJinan 250061China Department of Electrical and Electronic Engineering University of ManchesterManchester M139PLUK

Power system restoration has attracted more attention and made great progress recently. Research progress of the power system restoration from 2006 to 2016 is reviewed in this paper, including black-start, network reconfiguration and load restoration. Some emerging methods and key techniques are also discussed in the context of the integration of variable renewable energy and development of the smart grid. There is a long way to go to achieve automatic self-healing in bulk power systems because of its extreme complexity. However, rapidly developing artificial intelligence technology will eventually enable the step-by-step dynamic decision-making based on the situation awareness of supervisory control and data acquisition systems(SCADA) and wide area measurement systems(WAMS) in the near future.

关键词： Large-scale blackout Power system restoration Self-healing Smart grid Renewable energy Wide area measurement system(WAMS) Cyber attack

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Recent advances of nanoporous metal-based catalyst: synthesis, application and perspectives

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Journal of Iron and Steel Research International 2019年第8期26卷 779-795页

作者： rui-qi Yao Xing-you Lang qing Jiang Key Laboratory of Automobile Materials (Ministry of Education) School of Materials Science and Engineering Jilin University Changchun 130022 Jilin China

Nanoporous metal-based catalysts with the specific bicontinuous interconnected ligaments/pores network exhibit highly active performances in application for energy conversion, which represent a broader trend in the design of catalyst materials. These promising nanomaterials commendably provide highly conductive porous morphologies with reduced contact resistances, large electrochemical surface areas with enhanced catalytic efficiency, and controllable synthesis for regulating the performances. Thus, we highlight recent designs of nanoporous metals, alloys, transition metal compounds and hierarchical structures mainly employed in catalysis process. We discuss applied strategies to utilize characteristics of nanoporous metals in the energetic field of catalytic reactions. Moreover, development and evolution of novel controllable synthesis methods are applied in preparation of nanoporous non-noble metals and transition metal compounds. Finally, we present some outlooks and perspectives on the nanoporous metal catalyst and suggest ways for achieving alternative materials in catalysis applications.

关键词： Nanoporous metal Electrochemical catalyst Hierarchical structure Metal-based compound Structure-activity correlation

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Production of ultrafine iron powder by low-temperature hydrogen reduction: properties change with temperature

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Journal of Iron and Steel Research International 2024年第11期31卷 2645-2654页

作者： Min Gan En-di Guo Hao-rui Li Yun-can Cao Xiao-hui fan Zhi-yun Ji Zeng-qing Sun School of Minerals Processing and Bioengineering Central South UniversityChangsha410083HunanChina

Ultrafine iron powder is widely used due to its excellent performance. Hydrogen reduction of fine-grained high-purity iron concentrate to prepare ultrafine iron powder has the advantages of low energy consumption, pollution-free, and low cost. The hydrogen reduction of high-purity iron concentrates, characterized by the maximum particle size of 6.43 μm when the cumulative distribution is 50% and the maximum particle size of 11.85 μm when the cumulative distribution is 90% while the total iron content of 72.10%, was performed. The hydrogen reduction could be completed at 425 ℃, and the purity of ultrafine iron powders was more than 99 wt.% in the range of 425–650 ℃. Subsequently, the effect of reduction temperature on various properties of ultrafine iron powder was investigated, including particle morphology, particle size, specific surface area, lattice parameters, bulk density, and reaction activity. It was found that the reaction activity of the iron powders prepared by hydrogen reduction was much higher than that of the products of carbonyl and liquid phase synthesis. Below 500 ℃, the reduced iron powders were nearly unbound, with a small particle size and a low bulk density. The particles had a porous surface, with a specific surface area as high as 11.31 m^(2) g^(−1). The crystallization of reduced iron powders was imperfect at this time, the amorphization degree was prominent, and the interior contained a high mechanical storage energy, which had shown high reaction reactivity. It was suitable for catalysts, metal fuels, and other functionalized applications.

关键词： High-purity iron concentrate Hydrogen reduction Ultrafine iron powder Mechanical activation High reaction activity

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A novel texture clustering method based on shift invariant DWT and locality preserving projection

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第2期10卷 247-252页

作者： rui XING San-yuan ZHANG Le-qing ZHU School of Computer Science and Technology Zhejiang University Hangzhou 310027 China

We propose a novel texture clustering method. A classical type of(approximate) shift invariant discrete wavelet transform(DWT),dual tree DWT,is used to decompose texture images. Multiple signatures are generated from the obtained high-frequency bands. A locality preserving approach is applied subsequently to project data from high-dimensional space to low-dimensional space. Shift invariant DWT can represent image texture information efficiently in combination with a histogram signature,and the local geometrical structure of the dataset is preserved well during clustering. Experimental results show that the proposed method remarkably outperforms traditional ones.

关键词： Shift invariant DWT. Texture signature Local preserving clustering Dimension reduction k-means

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An Organic Solvent-free Approach towards PDI/Carbon Cloth Composites as Flexible Lithium Ion Battery Cathodes

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Chinese Journal of Polymer Science 2020年第5期38卷 540-549,I0008页

作者： Dong-qing Wu Deng Lu Peng Yang Lie Ma Biao Jiang Xin Xi fan-Cheng Meng Wen-Bei Zhang fan Zhang Qian-Qian Zhong rui-Li Liu School of Chemistry and Chemical Engineering Shanghai Jiao Tong UniversityShanghai200240China School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China

An acidic solution based method towards flexible lithium ion battery(LIB)cathodes is developed in this work with perylene diimide(PDI)as the electroactive component and carbon cloth(CC)as the current *** this approach,PDI is firstly dispersed in concentrated sulfuric acid(H2S04)and then deposited on CC substrate after the dilution of H2S04,which provides an organic solvent-free strategy to construct integrated LIB *** acdic solution based fabrication process also allows the facile adjusting of loading amounts of PDI in the cathodes,which can effectively influence the battery performances of the PDI/CC *** the result,the acidic solution processed PDI/CC cathode can deliver a high specific capacity of-36 mAh·g^-1 at the current density of 50 mA·g^-1 in both half cell with lithium foil as anode and full cell with pre-lithiated CC as *** both types of the batteries,the PDI/CC cathodes show good cycling stabilities by retaining^84%of the initial capacities after 300 charge-discharge cycles at 500 mA·g^-***,the excellent mechanical stability of the PDI/CC cathode enables the LIBs in pouch cell to maintain the electrochemical performances under various bending states,demonstrating their potentials for flexible LIBs.

关键词： Acidic solution processing Perylene diimide Carbon clothes Organic cathodes Flexible lithium ion batteries

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