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Combined hamartoma of the retina and retinal pigment epithelium:A case report

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World Journal of Clinical Cases 2023年第8期11卷 1788-1793页

作者： qing Ren Ning Han rui Zhang Ruo-fan Chen Peng Yu Department of Ophthalmology The Second Hospital of Jilin UniversityChangchun 130022Jilin ProvinceChina

BACKGROUND Combined hamartoma of the retina and retinal pigment epithelium(CHRRPE)is a rare congenital benign tumor which is commonly *** CHRRPE comprises slightly raised lesions at the posterior pole,with proliferation membrane often leading to vascular *** severe cases,macular edema,macular hole,retinal detachment or vitreous hemorrhage may *** with atypical clinical manifestations are prone to misdiagnosis by inexperienced *** SUMMARY A 33-year-old man reported onset of right eye blurred vision for one week *** segment and intraocular pressure were normal in both *** eye fundus photography was *** eye ophthalmoscopy showed vitreous hemorrhage and off-white raised retinal lesions below the optic *** membranes on the lesion surfaces resulted in superficial retinal detachment and tortuosity and occlusion of peripheral blood vessels.A horseshoe-like tear in the temporal periphery was surrounded by retinal *** coherence tomography revealed retinal thickening at the focal site with structural disturbance indicated by high *** eye ultrasound showed retinal thickening at the lesion,stretching and uplifting of the proliferative membrane,with moderately patchy echo at the optic disc *** and antibodies were detected in vitreous fluids during the operation to rule out other *** fluorescein angiography(FFA)at postoperative follow-up led to final diagnosis of *** FFA is helpful in diagnosing retinal and retinal pigment epithelial combined *** addition,other cytokine and etiological tests facilitate further differential diagnosis to rule out other suspected diseases.

关键词： Combined hamartoma of the retina and retinal pigment epithelium Ocular toxoplasmosis Fundus fluorescein angiography Vitreous hemorrhage Retinal tears Case report

THE CHARACTERISTICS AND ESTIMATION OF FLOW THROUGH A SINGLE ROUGH-WALLED FRACTURE

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Journal of Hydrodynamics 2012年第3期24卷 315-322页

作者： LIU qing-quan fan Hong-guang Laboratory-of Environmental Mechanics Institute of Mechanics Chinese Academy of Sciences Beijing 100190China

The flow through a single fracture is numerically studied by means of the Fluent Software. The results show that the roughness of the fracture significantly affects the hydraulic conductivity in the fracture as compared with the cubic law model widely used to describe the flow between two smooth parallel plates. A new model is proposed in this paper, the non-symmetric sinusoidal fracture model, to simulate the flow in a real fracture. This model involves two sinusoidal-varying walls with different phases to replace the flat planes in the cubic law model. The relationships between the effective hydraulic apertures and the phase retardation for different relative amplitudes and wavelengths are numerically investigated. A simple expression of the effective hydraulic aperture of the fracture is obtained, together with the law of the effective hydraulic aperture against the amplitude, the phase retardation and the wavelength of two sinusoidal-varying walls.

关键词： fracture seepage cubic law effective hydraulic aperture non-symmetric sinusoidal fracture

L_(2,1)-norm robust regularized extreme learning machine for regression using CCCP method

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The Journal of China Universities of Posts and Telecommunications 2023年第2期30卷 61-72页

作者： Wu qing Wang fan fan Jiulun Hou Jing School of Automation Xi'an University of Posts and TelecommunicationsXi'an 710121China School of Telecommunication and Information Engineering&School of Artificial Intelligence Xi'an University of Posts and TelecommunicationsXi'an 710121China School of Humanities and Foreign Languages Xi'an University of Posts and TelecommunicationsXi'an 710121China

As a way of training a single hidden layer feedforward network(SLFN),extreme learning machine(ELM)is rapidly becoming popular due to its ***,ELM tends to overfitting,which makes the model sensitive to noise and *** solve this problem,L_(2,1)-norm is introduced to ELM and an L_(2,1)-norm robust regularized ELM(L_(2,1)-RRELM)was proposed.L_(2,1)-RRELM gives constant penalties to outliers to reduce their adverse effects by replacing least square loss function with a non-convex loss *** light of the non-convex feature of L_(2,1)-RRELM,the concave-convex procedure(CCCP)is applied to solve its *** convergence of L_(2,1)-RRELM is also given to show its *** order to further verify the effectiveness of L_(2,1)-RRELM,it is compared with the three popular extreme learning algorithms based on the artificial dataset and University of California Irvine(UCI)*** each algorithm in different noise environments is tested with two evaluation criterions root mean square error(RMSE)and *** results of the simulation indicate that L_(2,1)-RRELM has smaller RMSE and greater fitness under different noise *** analysis shows that L_(2,1)-RRELM has better generalization performance,stronger robustness,and higher anti-noise ability and fitness.

关键词： extreme learning machine(ELM) non-convex loss L_(2,1)-norm concave-convex procedure(CCCP)

Atomistic Insights into the Irradiation Resistance of Co-Free High Entropy Alloy FeMnNiCr

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Acta Metallurgica Sinica(English Letters) 2024年第10期37卷 1657-1666页

作者： Chunhui Wang Lei Guo rui Li qing Peng School of Mechanical Engineering University of Science and Technology BeijingBeijing100083China State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of SciencesBeijing100190China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing100049China Guangdong Aerospace Research Academy Guangzhou511458China

We have investigated the displacement cascade irradiation resistance behavior of a cobalt-free high entropy alloy FeMnNiCr using molecular dynamics *** results show that defects in FeMnNiCr form in small clusters,and their migration is significantly inhibited,leading to a higher defect recombination rate and a lower number of residual defects compared to ***,FeMnNiCr exhibits a longer thermal peak life and lower thermal conductivity compared to Ni,providing a longer time for defect migration and *** migration of defect clusters in FeMnNiCr displays three-dimensional properties,attributed to its high chemical *** prolonged irradiation,defects in FeMnNiCr stabilize as small clusters,whereas point defects in Ni tend to form large defect clusters and evolve into *** the feature of absence of the element cobalt,our results imply that FeMnNiCr has great potential in application in nuclear energies.

关键词： High entropy alloys Displacement cascade Irradiation defects Molecular dynamics

Transition metal dichalcogenides (TMDCs) heterostructures: Optoelectric properties

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Frontiers of physics 2022年第4期17卷 15-30页

作者： rui Yang Jianuo fan Mengtao Sun School of Mathematics and Physics Beijing Advanced Innovation Center for Materials Genome EngineeringUniversity of Science and Technology BeijingBeijing 100083China

Transition metal dichalcogenides(TMDCs)have suitable and adjustable band gaps,high carrier mobility and *** TMDCs have attracted great attention due to the structure diversity,stable existence in normal temperature environment and the band gap corresponding to wavelength between infrared and visible *** ultra-thin,flat,almost defect-free surface,excellent mechanical flexibility and chemical stability provide convenient conditions for the construction of different types of TMDCs *** optoelectric properties of heterojunctions based on TMDCs materials are summarized in this *** electronic band structures of TMDCs heterojunctions lead to excellent optoelectric *** emitter,p-n diodes,photodetectors and photosensitive devices based on TMDCs heterojunction materials show excellent *** devices provide a prototype for the design and development of future high-performance optoelectric devices.

关键词： transition metal dichalcogenides(TMDCs) heterostructures,optoelectric properties

Probing new physics in dimension-8 neutral gauge couplings at e^+e^-colliders

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Science China(Physics,Mechanics & Astronomy) 2021年第2期64卷 2-26页

作者： John Ellis Hong-Jian He rui-qing Xiao Department of Physics Kings College LondonStrandLondonWC2R 2LSUK Theoretical Physics Department CERNCH-1211Geneva 23Switzerland NICPB Rävala 10Tallinn10143Estonia Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Key Laboratory for Particle Physics and CosmologyShanghai Jiao Tong UniversityShanghai200240China Institute of Modern Physics and Department of Physics Tsinghua UniversityBeijing100084China Center for High Energy Physics Peking UniversityBeijing100871China

Neutral triple gauge couplings(nTGCs)are absent in the standard model effective theory up to dimension-6 operators,but could arise from dimension-8 effective *** this work,we study the pure gauge operators of dimension-8 that contribute to nTGCs and are independent of the dimension-8 operator involving the Higgs *** show that the pure gauge operators generate both ZγZ^*and Zγγ^*vertices with rapid energy dependence∝E^5,which can be probed sensitively via the reaction e^+e^-→Zγ.We demonstrate that measuring the nTGCs via the reaction e^+e^-→Zγfollowed by Z→qq decays can probe the new physics scales of dimension-8 pure gauge operators up to the range(1-5)TeV at the CEPC,FCC-ee and ILC colliders with s~(1/2)=(0.25-1)TeV,and up to the range(10-16)TeV at CLIC with s~(1/2)=(3-5)TeV,assuming in each case an integrated luminosity of 5 ab~(-1).We compare these sensitivities with the corresponding probes of the dimension-8 nTGC operators involving Higgs doublets and the dimension-8 fermionic contact operators that contribute to the e^+e^-Zγvertex.

关键词： neutral triple gauge couplings new physics beyond the standard model effective field theory e^+e^-colliders

Smooth support vector machine based on piecewise function

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The Journal of China Universities of Posts and Telecommunications 2013年第5期20卷 122-128页

作者： WU qing fan Jiu-lun School of Automation Xi'an University of Posts and Telecommunications School of telecommunication and information engineering Xi'an University of Posts and Telecommunications

Support vector machines （SVMs） have shown remarkable success in many applications. However, the non-smooth feature of objective function is a limitation in practical application of SVMs. To overcome this disadvantage, a twice continuously differentiable piecewise-smooth function is constructed to smooth the objective function of unconstrained support vector machine （SVM）, and it issues a piecewise-smooth support vector machine （PWESSVM）. Comparing to the other smooth approximation functions, the smooth precision has an obvious improvement. The theoretical analysis shows PWESSVM is globally convergent. Numerical results and comparisons demonstrate the classification performance of our algorithm is better than other competitive baselines.

关键词： SVM smooth technique piecewise function bound of convergence

Instanton Effects on Gluon Propagator

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Communications in Theoretical Physics 2002年第10期38卷 449-454页

作者： fan Xiao-Bin WANG qing Department of Physics Tsinghua University Beijing 100084 China Department of Physics Tsinghua University Beijing 100084 China Institute of Theoretical Physics Academia Sinica Beijing 100080 China

Gluon propagator is investigated for pure Yang-Mills SU(3) gauge theory in field-strength approach. It isfound that instantohs provide a homogeneous solid-like medium background which generates finite nonzero momentum... 详细信息

关键词： gluon propagator, instanton

Shenfu injection attenuates lipopolysaccharide-induced myocardial inflammation and apoptosis in rats

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Chinese Journal of Natural Medicines 2020年第3期18卷 226-233页

作者： CHEN rui-Juan rui qing-Lin WANG Qiong TIAN fang WU Jian KONG Xiang-qing Cardiology Department the First Affiliated Hospital with Nanjing Medical UniversityNanjing 210029China Emergency Department Affiliated Hospital of Nanjing University of Chinese MedicineJiangsu Province Hospital of Chinese MedicineNanjing 210029China Clinical Pharmacology Department Affiliated Hospital of Nanjing University of Chinese MedicineJiangsu Province Hospital of Chinese MedicineNanjing 210029China Central Laboratory Affiliated Hospital of Nanjing University of Chinese MedicineJiangsu Province Hospital of Chinese MedicineNanjing 210029China

Shenfu injection(SFI), a Chinese medicinal product, shows potent efficacy in treating sepsis. The aim of the present study was to clarify the protective effects of SFI against lipopolysaccharide(LPS)-induced myocardial inflammation and *** were carried out in Sprague-Dawley(SD) rats treated with LPS or LPS + SFI, and in H9 C2 cardiomyocytes. The sepsisassociated myocardial inflammation and apoptosis was induced by the intraperitoneal injection of LPS(20 mg·kg–1). SFI attenuated the increased expression of tumor necrosis factor(TNF)-α and interleukin(IL)-1β induced by LPS both in serum and heart. In LPS group,cell viability was reduced, and reversed after SFI administration. LPS treatment increased the expression levels of cleaved-caspase 3 and Bax, and those of Bcl2 and Bcl2/Bax. These two trends were reversed by SFI administration. The expression levels of phosphorylated mitogen-activated protein kinase kinase(p-MEK) and phosphorylated extracellular regulated protein kinases(p-ERK) were increased by LPS, and reversed by SFI. MEK inhibitor U0126 attenuated the apoptosis induced by LPS. These results indicate that SFI could treat LPS-induced cardiac dysfunction. In conclusion, SFI attenuates the inflammation and apoptosis induced by LPS via downregulating the MEK and ERK signaling pathways.

关键词： Shenfu injection Lipopolysaccharide Inflammation Apoptosis Mitogen-activated protein kinase kinase Extracellular regulated protein kinases