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通讯和计算机（中英文版） 2008年第5期5卷 36-39页

作者： HUANG You-rui TANG Chao-li wang Shuang Anhui University of Science and Technology Huainan 232001 China

Collagen Type I Alpha 1 Mutation Causes Osteogenesis Imperfecta from Mild to Perinatal Death in a Chinese Family

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Chinese Medical Journal 2016年第1期129卷 88-91页

作者： Hong-Yan liu Jia Huang Dong Wu Tao li liang-Jie Guo Qian-Nan Guo Hong-Dan wang rui-li wang Yue wang Department of Medical Genetics Institute People's Hospital of Zhenzhou University (Henan Provincial People's Hospital) Zhenzhou Henan 450053 China Department of Ultrasonic Diagnosis People's Hospital of Zhenzhou University (Henan Provincial People's Hospital) Zhengzhou Henan 450003 China Department of Gynecology and Obstetrics People's Hospital of Zhenzhou University (Henan Provincial People's Hospital) Zhengzhou Henan 450003 China

Osteogenesis imperfecta （01）, also known as brittle bone disease or Lobstein syndrome, is characterized by blue or gray sclerae, variable short stature, dentinogenesis imperfecta, hearing loss, and recurrent fractures. Based on clinical, genetic, and radiological features, Sillence et al. classified the OI into four subtypes including type I： Mild, common, with blue sclera; type Ⅱ： Perinatal lethal form; type Ⅲ： Severe and age-related progressive detbrmity, with normal sclera; and type Ⅳ： Moderate severity with normal sclera.

关键词： Collagen Type I Alpha 1 Gene Mutation Molecular Diagnosis: Osteogenesis Imperfecta

Scanning electron microscopic observation:three-dimensional architecture of the collagen in hepatic fibrosis rats

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Chinese Medical Journal 2007年第4期120卷 308-312页

作者： wang Xiao-hong ZHAO Jing ZHANG Wei-guang ZHANG li-ying, MA rui-qiong wang li-qin ZHANG Shu-yong TIAN Long Department of Anatomy and Histoembryology Peking UniversityHealth Science Center Beijing 100083 China

Background In the process of hepatic fibrosis, the accumulation of collagen fibers is strongly related to the hepatic function. The aim of this study was to investigate the three-dimensional architecture of the collagen network in the liver of rats with hepatic fibrosis. Methods Healthy adult male Wistar rats （n=32） were randomly divided into a control group （n=16） and a hepatic fibrosis group （n=16）. In the control group, the rats were treated with peanut oil while the rats in hepatic fibrosis group were treated for 10 weeks with 60% CCI4 diluted in peanut oil. The quantity of collagen fibers was detected by Western blotting; distribution of the collagen was detected by sirius red staining and polarized microscope; the three-dimensional architecture of collagen in the liver was observed under the scanning electron microscope after fixed tissues were treated with cell-maceration using NaOH. Statistical analysis was performed using the u test. Results The quantity of collagen fibers increased significantly in the hepatic fibrosis group. With the aggravation of hepatic fibrosis, collagen fibers gradually accumulated. They interlaced the reticulation compartment and formed a round or ellipse liver tissue conglomeration like a grape framework that was disparate and wrapped up the normal liver Iobule. The deposition of collagen fibers was obvious in adjacent hepatic parenchyma, especially around the portal tracts. Conclusion Our experiment showed the collagen proliferation and displays clearly the three-dimensional architecture of collagen fibers in rat liver with hepatic fibrosis by scanning electron microscope. It can provide a morphological foundation for the mechanisms of changed haemodynamics and portal hypertension in hepatic fibrosis.

关键词： hepatic fibrosis collagen fibers scanning electron microscope three-dimensional construct

Constraints on holographic QCD phase transitions from PTA observations

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 71-78页

作者： Song He li li Sai wang Shao-Jiang wang Center for Theoretical Physics and College of Physics Jilin University School of Physical Science and Technology Ningbo University Max Planck Institute for Gravitational Physics (Albert Einstein Institute) CAS Key Laboratory of Theoretical Physics Institute of Theoretical Physics Chinese Academy of Sciences School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of Sciences (UCAS) School of Physical Sciences University of Chinese Academy of Sciences (UCAS) Theoretical Physics Division Institute of High Energy Physics Chinese Academy of Sciences

The underlying physics of QCD phase transition in the early Universe remains largely unknown due to its strong-coupling nature during the quark-gluon plasma/hadron gas transition, yet a holographic model has been proposed to quantitatively fit the lattice QCD data while with its duration of the first-order phase transition(FoPT) left undetermined. At specific baryon chemical potential, the first-order QCD phase transition agrees with the observational constraint of baryon asymmetry. It, therefore, provides a scenario for phase transition gravitational waves(GWs) within the standard model of particle physics. If these background GWs could contribute dominantly to the recently claimed common-spectrum red noise from pulsar timing array(PTA) observations, the duration of this FoPT can be well constrained, and the associated primordial black holes are still allowed by current observations.

关键词： pulsar timing array QCD phase transition gravitational waves primordial black holes

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硫酸氨基葡萄糖胶囊生物等效性研究基本考虑

中国新药杂志 2018年第6期27卷 634-636页

作者：王玉杨进波贺锐锐李丽王玉珠国家食品药品监督管理总局药品审评中心北京100038

氨基葡萄糖是一种新型骨关节炎治疗药物,其药动学相关的血药浓度研究显得尤为重要,但氨基葡萄糖为人体内源性物质,除了人体内自然存在的氨基葡萄糖以外,还有许多其他内源性糖等物质也存在干扰,且内源性氨基葡萄糖具有浓度低和受试者间... 详细信息

氨基葡萄糖是一种新型骨关节炎治疗药物,其药动学相关的血药浓度研究显得尤为重要,但氨基葡萄糖为人体内源性物质,除了人体内自然存在的氨基葡萄糖以外,还有许多其他内源性糖等物质也存在干扰,且内源性氨基葡萄糖具有浓度低和受试者间变异性较高的特点。因此,若想准确地检测到外源性氨基葡萄糖在血浆中的浓度,在选择使用具有较高灵敏度和选择性的方法的前提下,还需要减去内源性氨基葡萄糖的基线值来排除干扰。

关键词：氨基葡萄糖生物等效性检测方法内源性物质基线干扰

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伊宁地块石炭纪火山岩及其对构造演化的约束

岩石学报 2017年第1期33卷 1-15页

作者：李永军吴乐李书领李甘雨沈锐李钊王祚鹏汪振宇长安大学地球科学与资源学院西安710054 国土资源部岩浆作用成矿与找矿重点实验室西安710054

西天山伊宁地块的构造格局及其演化之认识久存争议,倍受关注。分歧焦点有三:(1)石炭纪有无洋盆存在?(2)若有洋盆,何时闭合?(3)'沟-弧-盆'消亡时究竟是单向俯冲还是双向俯冲?若是单向俯冲,俯冲方向是由北向南或是相反(即俯冲极性)?因此,... 详细信息

西天山伊宁地块的构造格局及其演化之认识久存争议,倍受关注。分歧焦点有三:(1)石炭纪有无洋盆存在?(2)若有洋盆,何时闭合?(3)'沟-弧-盆'消亡时究竟是单向俯冲还是双向俯冲?若是单向俯冲,俯冲方向是由北向南或是相反(即俯冲极性)?因此,这些重大地质问题均聚焦于本区的火山岩。石炭纪火山岩是伊宁地块中的最主要建造和指示构造演化的关键层位,争论长久而激烈。本文认为,伊宁地块早石炭世发育弧前-岛弧-弧后盆地钙碱性火山-沉积建造,是塔里木板块北缘的主要组成部分;而晚石炭世碱性系列双峰式火山岩及其沉积组合则是大陆裂谷火山-沉积建造,形成于区域性伸展构造环境,是准噶尔板块与塔里木板块缝合后的陆内建造,因而古洋盆的关闭时限是早石炭世晚期(鄯善运动)。依据区内早石炭世建造的空间分布和变化规律,作者们认为古天山洋盆与当今地学界作为典型的日本沟-弧-盆体系有着极好的相似性和空间分布可对比性。石炭纪火山岩为本区的构造演化研究提供了重要的约束信息。

关键词：火山岩古构造格局与演化石炭纪伊宁地块西天山

Design of a cationic accelerator enabling ultrafast ion diffusion kinetics in aqueous zinc-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 377-384页

作者： Yawei Xiao Qianqian Gu Haoyu li Mengyao li Yude wang National Center for International Research on Photoelectric and Energy Materials School of Materials and Energy Yunnan University Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources School of Chemistry and Chemical Engineering Hainan University College of Chemical Engineering Fuzhou University Yunnan Key Laboratory of Carbon Neutrality and Green Low-carbon Technologies Yunnan University

Aqueous zinc-ion batteries are highly favored for grid-level energy storage owing to their low cost and high safety,but their practical application is limited by slow ion *** address this,a strategy has been developed to create a cation-accelerating electric field on the surface of the cathode to achieve ultrafast Zn2+diffusion *** employing electrodeposition to coat MoS2on the surface of BaV6O16·3H2O nanowires,the directional built-in electric field generated at the heterointerface acts as a cation accelerator,continuously accelerating Zn2+diffusion into the active *** optimized Zn2+diffusion coefficient in CC@BaV-6O16·3H2O@MoS2(7.5×10～8cm2s-1) surpasses that of most reported V-based ***,MoS2serving as a cathodic armor extends the cycling life of the Zn-CC@BaV6O16·3H2O@MoS2full batteries to over 10000 *** work provides valuable insights into optimizing ion diffusion kinetics for high-performance energy storage devices.

关键词： Internal electric field Cationic accelerator Ion diffusion kinetics Cathode modification strategy Aqueous zinc ion battery

结合多分类RVM和DS的弹道目标HRRP融合识别方法

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信息与控制 2017年第1期46卷 65-71,102页

作者：李睿王晓丹雷蕾薛爱军空军工程大学防空反导学院陕西西安710051

多特征融合可以有效提高目标识别正确率.本文将相关向量机(relevance vector machine,RVM)二类分类模型扩展为多类分类概率模型MRVM(multi-class relevance vector machine,MRVM),然后与DS证据理论相结合,用于弹道中段目标高分辨距离像(... 详细信息

多特征融合可以有效提高目标识别正确率.本文将相关向量机(relevance vector machine,RVM)二类分类模型扩展为多类分类概率模型MRVM(multi-class relevance vector machine,MRVM),然后与DS证据理论相结合,用于弹道中段目标高分辨距离像(high resolution range profile,HRRP)分类和融合识别,提出了结合MRVM和DS的HRRP融合识别方法.该方法充分利用了多类分类RVM输出的概率信息,解决了用DS证据理论进行融合时基本概率赋值获取问题.仿真实验结果表明MRVM估计的样本后验概率更准确,融合识别后的正确率更高.

关键词：目标识别高分辨距离像相关向量机 DS证据理论

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基于RVM的多类分类概率输出方法

计算机科学 2017年第3期44卷 242-246页

作者：李睿王晓丹空军工程大学防空反导学院西安710051

基于相关向量机(Relevance Vector Machine,RVM)可以输出各类别成员概率的特点,对RVM二分类模型分别采用多元sigmoid方法和pairwise coupling方法,将其扩展为一对多分类器和一对一分类器,实现了多类分类及概率输出。基于人工高斯数据集... 详细信息

基于相关向量机(Relevance Vector Machine,RVM)可以输出各类别成员概率的特点,对RVM二分类模型分别采用多元sigmoid方法和pairwise coupling方法,将其扩展为一对多分类器和一对一分类器,实现了多类分类及概率输出。基于人工高斯数据集和UCI数据集的实验仿真结果表明,所提方法不仅能够准确地求解样本后验概率,而且运行效率也比较高,同时能够保证较高的分类正确率。

关键词：相关向量机多类分类概率成对分解

Overview of in-situ oxygen production technologies for lunar resources

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 233-255页

作者： Youpeng Xu Sheng Pang liangwei Cong Guoyu Qian Dong wang Laishi li Yusheng Wu Zhi wang College of Materials Science and Engineering Shenyang University of TechnologyShenyang 110870China CAS Key Laboratory of Green Process and Engineering National Engineering Research Center for Green Recycling of Strategic Metal ResourcesInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China Innovation Academy for Green Manufacture Chinese Academy of SciencesBeijing 100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing 100049China

The rich resources and unique environment of the Moon make it an ideal location for human expansion and the utilization of extraterrestrial ***,crucial for supporting human life on the Moon,can be extracted from lunar regolith,which is highly rich in oxygen and contains polymetallic *** oxygen and metal extraction can be achieved using existing metallurgical ***,the ample reserves of water ice on the Moon offer another means for oxygen *** paper offers a detailed overview of the leading technologies for achieving oxygen production on the Moon,drawing from an analysis of lunar resources and environmental *** delves into the principles,processes,advantages,and drawbacks of water-ice electrolysis,two-step oxygen production from lunar regolith,and one-step oxygen production from lunar *** two-step methods involve hydrogen reduction,carbothermal reduction,and hydrometallurgy,while the one-step methods encompass fluorination/chlorination,high-temperature decomposition,molten salt electrolysis,and molten regolith electrolysis(MOE).Following a thorough comparison of raw materials,equipment,technology,and economic viability,MOE is identified as the most promising approach for future in-situ oxygen production on the *** the corrosion characteristics of molten lunar regolith at high temperatures,along with the Moon's low-gravity environment,the development of inexpensive and stable inert anodes and electrolysis devices that can easily collect oxygen is critical for promoting MOE technology on the *** review significantly contributes to our understanding of in-situ oxygen production technologies on the Moon and supports upcoming lunar exploration initiatives.

关键词： lunar resources in-situ oxygen production space metallurgy molten lunar regolith electrolysis