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Sedimentary architecture of submarine channel-lobe systems under different seafloor topography:Insights from the Rovuma Basin offshore East Africa

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Petroleum Science 2024年第1期21卷 125-142页

作者： Mei Chen Sheng-He Wu rui-feng wang Jia-Jia Zhang Peng-Fei Xie Min wang Xiao-feng wang Ji-Tao Yu Qi-Cong Xiong State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing102249China College of Geosciences China University of Petroleum(Beijing)Beijing102249China Faculty of Geosciences University of BremenBremen28359Germany MARUM-Center for Marine and Environmental Sciences University of BremenBremen28359Germany Research institute of Petroleum Exploration and Development PetroChinaBeijing10083China School of Geosciences Yangtze UniversityWuhan 100083HubeiChina CNODC Mozambique Ltd. Beijing 100034China

Seafloor topography plays an important role in the evolution of submarine ***,it is still not so clear how the shape of slope affects the three-dimensional(3-D)architecture of submarine *** this study,we analyze the effect of topography factors on different hierarchical lobe architectures that formed during Pliocene to Quaternary in the Rovuma Basin offshore East *** characterize the shape,size and growth pattern of different hierarchical lobe architectures using 3-D seismic *** find that the relief of the topographic slope determines the location of preferential deposition of lobe complexes and single *** the topography is irregular and presents topographic lows,lobe complexes first infill these *** lobes are deposited preferentially at positions with higher longitudinal(***-slope)slope *** the longitudinal slope becomes higher,the aspect ratio of the single lobes ***(***-slope)topography does not seem to have a strong influence on the shape of single lobe,but it seems to affect the overlap of single *** the lateral slope gradient is relatively high,the single lobes tend to have a larger overlap ***,as the average of lateral slope and longitudinal slope gets greater,the width/thickness ratio of the single lobe is smaller,*** tend to accumulate *** results demonstrate that the shape of slopes more comprehensively influences the 3-D architecture of lobes in natural deep-sea systems than previously other lobe deposits and analogue experiments,which helps us better understand the development and evolution of the distal parts of turbidite systems.

关键词： Submarine fan Seafloor topography Sedimentary architecture Slope system SW Indian ocean

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A convenient synthesis of 2-aryl substituted benzo[f][1,2,4]triazolo[1,5-a]azepine derivatives

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Chinese Chemical Letters 2007年第7期18卷 785-787页

作者： Qing Qing Meng He Xiang Bai feng Li Quan rui wang feng Gang Tao Department of Chemistry Fudan University Shanghai 200433 China

A convenient synthetic pathway to 2-aryl-5,6-dihydro-4H-benzo[f][1,2,4]triazolo[1,5-a]azepine derivatives 7 was *** synthesis was based on the cycloaddition of the 1,2,3,4-tetrahydronaphthalene α-acetoxy azo compound... 详细信息

关键词： Benzotriazoloazepine Nitriles 1,3-Dipolar cycloaddition Ring expansion

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An effective synthesis of β-aryl substituted isotetronic acids via Suzuki coupling

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Chinese Chemical Letters 2008年第11期19卷 1309-1311页

作者： Huan Sheng Chen Xia Ping Ma Zhi Ming Li Quan rui wang feng Gang Tao Department of Chemistry Fudan University Shanghai 200433 China

Isotetronic acids are of great agricultural and pharmacological relevance and occur in a number of natural products. A convenient synthetic pathway to β-aryl substituted isotetronic acid derivatives was developed via Suzuki cross-coupling of the corresponding β-bromo substituted isotetronic acid derivatives with arylboronic acids under palladium acetate catalysis. Good to excellent yields have been achieved

关键词： lsotetronic acids Palladium Suzuki coupling Arylboronic acids

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一种用于船舶纵-横联合减摇的预测控制器（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2016年第5期17卷 399-415页

作者： Wen-yang DUAN Yang HAN rui-feng wang Li-min HUANG Department of Shipbuilding Engineering Harbin Engineering University Harbin 150001 China Huhhot Railway Bureau Huhhot 010000 China

目的:为提高船舶运动联合减摇效果,提出一种基于船舶运动及船舶水动力预报的联合减摇控制方法,并基于弱非线性二维半方法进行数值仿真,分析该控制方法的减摇控制效果。创新点:1.提出基于船舶运动预报和水动力预报的减摇方法,克服了控制... 详细信息

目的:为提高船舶运动联合减摇效果,提出一种基于船舶运动及船舶水动力预报的联合减摇控制方法,并基于弱非线性二维半方法进行数值仿真,分析该控制方法的减摇控制效果。创新点:1.提出基于船舶运动预报和水动力预报的减摇方法,克服了控制时延对减摇效果的影响;2.基于弱非线性二维半方法进行船舶运动减摇数值仿真,验证了该方法能够实现良好的联合减摇控制效果。方法:1.在控制过程中基于极短期预报方法预报船舶运动姿态,并利用船舶运动方程预报水动力,将预报的水动力作为鳍角分配的依据;2.基于弱非线性二维半方法在时域内进行船舶运动减摇数值仿真,分析该控制方法在各种不同海况下的减摇控制效果。结论:1.弱非线性二维半方法在高速船舶的水动力预报中可以获得良好的效果;2.在各个不同海况下,本文提出的控制方法能够实现有效的联合减摇。

关键词：主动鳍联合减摇预测控制器船舶运动和水动力预报控制器

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Experimental observation of pseudogap in a modulation-doped Mott insulator:Sn/Si(111)-(√3×√3)R30°

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Chinese Physics B 2022年第6期31卷 115-119页

作者： Yan-Ling Xiong Jia-Qi Guan rui-feng wang Can-Li Song Xu-Cun Ma Qi-Kun Xue State Key Laboratory of Low-Dimensional Quantum Physics Department of PhysicsTsinghua UniversityBeijing 100084China Frontier Science Center for Quantum Information Beijing 100084China Beijing Academy of Quantum Information Sciences Beijing 100193China Southern University of Science and Technology Shenzhen 518055China

Unusual quantum phenomena usually emerge upon doping Mott *** a molecular beam epitaxy system integrated with cryogenic sc√annin√g tunneling microscope,we investigate the electronic structure of a modulation-doped Mott insulator Sn/Si(111)-(√3×√3)R30°.In underdoped regions,we observe a universal pseudogap opening around the Fermi level,which changes little with the applied magnetic field and the occurrence of Sn *** pseudogap gets smeared out at elevated temperatures and alters in size with the spatial confinement of the Mott insulating *** findings,along with the previously observed superconductivity at a higher doping level,are highly reminiscent of the electronic phase diagram in the doped copper oxide compounds.

关键词： pseudogap(PG) modulation doping Mott insulator scanning tunneling microscope(STM)

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Nation-Teflon bimembrane-supported palladium catalysts for Suzuki coupling reactions

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Chinese Chemical Letters 2007年第12期18卷 1460-1462页

作者： Li Ting Chai Yang Zhou Li Wei Wei wang Quan rui wang feng Gang Tao Department of Chemistry Fudan University 200433 Shanghai PR China

Nation-Teflon bimembrane was used as an efficient support for the preparation and application of heterogeneous palladium catalysts. The supported palladium catalysts exhibit high activity and stability in the Suzuki cross-coupling of aryl bromides with arylboronic acids to afford the corresponding biaryls in good to excellent yields, and can be readily recovered and reused several times without significant loss of activity.

关键词： Nation-Teflon bimembrane-supported Palladium catalysts Suzuki reaction Biaryl

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Computed tomography-based radiomic model for the prediction of neoadjuvant immunochemotherapy response in patients with advanced gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第10期16卷 4115-4128页

作者： Jun Zhang Qi wang Tian-Hui Guo Wen Gao Yi-Miao Yu rui-feng wang Hua-Long Yu Jing-Jing Chen Ling-Ling Sun Bi-Yuan Zhang Hai-Ji wang Department of Radiation Oncology Affiliated Hospital of Qingdao UniversityQingdao 266000Shandong ProvinceChina Department of Radiology Affiliated Hospital of Qingdao UniversityQingdao 266000Shandong ProvinceChina Department of Pathology Affiliated Hospital of Qingdao UniversityQingdao 266000Shandong ProvinceChina

BACKGROUND Neoadjuvant immunochemotherapy(nICT)has emerged as a popular treatment approach for advanced gastric cancer(AGC)in clinical practice ***,the response of AGC patients to nICT displays significant heterogeneity,and no existing radiomic model utilizes baseline computed tomography to predict treatment *** To establish a radiomic model to predict the response of AGC patients to *** Patients with AGC who received nICT(n=60)were randomly assigned to a training cohort(n=42)or a test cohort(n=18).Various machine learning models were developed using selected radiomic features and clinical risk factors to predict the response of AGC patients to *** individual radiomic nomogram was established based on the chosen radiomic signature and clinical *** performance of all the models was assessed through receiver operating characteristic curve analysis,decision curve analysis(DCA)and the Hosmer Lemeshow goodness-of-fit *** The radiomic nomogram could accurately predict the response of AGC patients to *** the test cohort,the area under curve was 0.893,with a 95%confidence interval of *** indicated that the clinical application of the radiomic nomogram yielded greater net benefit than alternative *** A nomogram combining a radiomic signature and a clinical signature was designed to predict the efficacy of nICT in patients with *** tool can assist clinicians in treatment-related decision-making.

关键词： Gastric cancer Radiomics Computed tomography Neoadjuvant immunochemotherapy Machine learning Immunology

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Development and external validation of models to predict acute respiratory distress syndrome related to severe acute pancreatitis

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World Journal of Gastroenterology 2022年第19期28卷 2123-2136页

作者： Yun-Long Li Ding-Ding Zhang Yang-Yang Xiong rui-feng wang Xiao-Mao Gao Hui Gong Shi-Cheng Zheng Dong Wu Department of Gastroenterology Peking Union Medical College HospitalBeijing 100730China Medical Research Center Peking Union Medical College HospitalBeijing 100730China Clinical Epidemiology Unit International Clinical Epidemiology NetworkBeijing 100730China Department of Gastroenterology The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina Department of Gastroenterology The Fourth Affiliated Hospital of Harbin Medical UniversityHarbin 150001Heilongjiang ProvinceChina Department of Gastroenterology The Sixth Hospital of BeijingBeijing 100191China Department of Gastroenterology West China Longquan Hospital Sichuan UniversityChengdu 610100Sichuan ProvinceChina

BACKGROUND Acute respiratory distress syndrome(ARDS)is a major cause of death in patients with severe acute pancreatitis(SAP).Although a series of prediction models have been developed for early identification of such patients,the majority are complicated or lack validation.A simpler and more credible model is required for clinical *** To develop and validate a predictive model for SAP related *** Patients diagnosed with AP from four hospitals located at different regions of China were retrospectively grouped into derivation and validation *** significant variables were identified using the least absolute shrinkage and selection operator regression *** models with nomograms were further built using multiple logistic regression analysis with these picked *** discriminatory power of new models was compared with some common *** performance of calibration ability and clinical utility of the predictive models were *** Out of 597 patients with AP,139 were diagnosed with SAP(80 in derivation cohort and 59 in validation cohort)and 99 with ARDS(62 in derivation cohort and 37 in validation cohort).Four identical variables were identified as independent risk factors for both SAP and ARDS:heart rate[odds ratio(OR)=1.05;95%CI:1.04-1.07;P<0.001;OR=1.05,95%CI:1.03-1.07,P<0.001],respiratory rate(OR=1.08,95%CI:1.0-1.17,P=0.047;OR=1.10,95%CI:1.02-1.19,P=0.014),serum calcium concentration(OR=0.26,95%CI:0.09-0.73,P=0.011;OR=0.17,95%CI:0.06-0.48,P=0.001)and blood urea nitrogen(OR=1.15,95%CI:1.09-1.23,P<0.001;OR=1.12,95%CI:1.05-1.19,P<0.001).The area under receiver operating characteristic curve was 0.879(95%CI:0.830-0.928)and 0.898(95%CI:0.848-0.949)for SAP prediction in derivation and validation cohorts,*** value was 0.892(95%CI:0.843-0.941)and 0.833(95%CI:0.754-0.912)for ARDS prediction,*** discriminatory power of our models was improved compared with that of other widely used

关键词： Acute pancreatitis Acute respiratory distress syndrome Nomogram Calibration Early identification Predictive model

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Transjugular intrahepatic portosystemic shunt for pyrrolizidine alkaloid-related hepatic sinusoidal obstruction syndrome

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World Journal of Gastroenterology 2020年第24期26卷 3472-3483页

作者： Chun-Ze Zhou rui-feng wang Wei-Fu Lv Yu-Qin Fu De-Lei Cheng Yi-Jiang Zhu Chang-Long Hou Xian-Jun Ye Interventional Radiology Medical College of Shandong UniversityJinan 250021Shandong ProvinceChina Interventional Radiology Department The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Nephrology The Second HospitalCheeloo College of MedicineShandong UniversityJinan 250033Shandong ProvinceChina Department of Ultrasound The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina

BACKGROUND Treatments for hepatic sinusoidal obstruction syndrome(HSOS)are *** To evaluate transjugular intrahepatic portosystemic shunting(TIPS)as a treatment for pyrrolidine alkaloid-related HSOS(PA-HSOS).METHODS This retrospective analysis included patients with PA-HSOS admitted to the First Affiliated Hospital of the University of Science and Technology of China(June 2015 to January 2019).Baseline clinical characteristics and follow-up data were extracted from the medical *** patients included in this study experienced failure of initial *** were divided into the TIPS and conservative treatment groups according to the therapy they *** function,maximal ascites depth,imaging characteristics,pathology findings,and survival were compared between *** The TIPS group included 37 patients(28 males),and the conservative treatment group included 17 patients(11 males).Baseline characteristics were similar between *** were two deaths in the TIPS group and seven deaths in the conservative treatment group during follow-up(3-48 mo).The 3-,6-,12-and 24-mo survival rates were 94.6%,94.6%,94.6%and 94.6%,respectively,in the TIPS group and 70.6%,57.8%,57.8%and 57.8%,respectively,in the conservative treatment ***-Meier analysis revealed significantly longer survival for the TIPS group than for the conservative treatment group(P=0.001).Compared with the pre-treatment value,maximal ascites depth was significantly lower at 1 wk,2 wk,1 mo,and 3 mo for the TIPS group(all P<0.05)but not in the conservative treatment ***-enhanced computed tomography demonstrated the disappearance of patchy liver enhancement after *** showed that liver congestion and hepatocyte swelling improved with time after TIPS *** TIPS may achieve better outcomes than conventional symptomatic treatment in patients with PA-HSOS.

关键词： Transjugular intrahepatic portosystemic shunt Sinusoidal obstruction syndrome Pyrrolizidine alkaloids Survival Ascites

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Comparative study on the stem cell phenotypes of C6 cells under different culture conditions

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Chinese Medical Journal 2011年第19期124卷 3118-3126页

作者： ZHANG Suo-jun YE Fei XIE rui-fan HU feng wang Bao-feng WAN feng GUO Dong-sheng LEI Ting Department of Neurosurgery and Neuro-Oncology Molecular Biology Laboratory Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430030 China

Background Glioma stem cell （GSC） hypothesis posits that a subpopulation of cells within gliomas have true clonogenic and tumorigenic potential. Significantly, a more controversial correlate to GSC is that cells in different culture conditions might display distinct stem cell properties. Considering these possibilities, we applied an approach comparing stem cell characteristics of C6 glioma cells under different culture *** C6 cells were cultured under three different growth conditions, i.e., adherent growth in conventional 10% serum medium, non-adherent spheres growth in serum-free medium, as well as adherent growth on laminin-coated flask in serum-free medium. Growth characteristics were detected contrastively through neurosphere formation assay and cell cycle analysis. Markers were determined by immunofluorescence, relative-quantitative reverse transcription （RT）-PCR,Western blotting and flow cytometry. Side population cells were analyzed via flow cytometry. Tumor models were detected by magnetic resonance imaging and hematoxylin ＆ eosin staining. Data analyses were performed with SPSS software （17.0）.Results C6 cells （C6-Adh, C6-SC-Sph and C6-SC-Adh） showed distinctive growth patterns and proliferation *** to suspending C6-SC-Sph, adherent C6-Adh and C6-SC-Adh displayed higher growth ratio. C6-SC-Sph and C6-SC-Adh showed enhanced capability of neurosphere formation and self-renewal. High side population ratio was detected in C6-SC-Sph and C6-SC-Adh. CD133 was not detected in all three kinds of cells. Conversely, Nestin and β-Ⅲ-tubulin were demonstrated positive, nonetheless with no statistical significance （P 〉0.05）. Interestingly, lower expression of glial fibrillary acidic protein was demonstrated in C6-SC-Sph and C6-SC-Adh. C6-Adh, C6-SC-Sph and C6-SC-Adh were all displayed in situ oncogenicity, while statistical difference of survival time was not *** C6 glioma cell line is endowed with some GSC phenotypes that

关键词： C6 glioma stem cell neurosphere CD133 side population laminin

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