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Molecular mechanism of flowering time regulation in Brassica rapa:similarities and differences with Arabidopsis

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Horticultural Plant Journal 2024年第3期10卷 615-628页

作者： Na li rui Yang Shuxing Shen Jianjun Zhao State Key Laboratory of North China Crop Improvement and Regulation Key Laboratory of Vegetable Germplasm Innovation and Utilization of HebeiCollaborative Innovation Center of Vegetable Industry in HebeiCollege of HorticultureHebei Agricultural UniversityBaodingHebei 071000China

Properly regulated flowering time is pivotal for successful plant *** floral transition from vegetative growth to reproductive growth is regulated by a complex gene regulatory network that integrates environmental signals and internal conditions to ensure that flowering takes place under favorable *** rapa is a diploid Cruciferae species that includes several varieties that are cultivated as vegetable or oil *** time is one of the most important agricultural traits of *** crops because of its influence on yield and *** transition to flowering in *** is regulated by several environmental and developmental cues,which are perceived by several signaling pathways,including the vernalization pathway,the autonomous pathway,the circadian clock,the thermosensory pathway,and gibberellin(GA)*** signals are integrated to control the expression of floral integrators BrFTs and BrSOC1s to regulate *** this review,we summarized current research advances on the molecular mechanisms that govern flowering time regulation in *** and compare this to what is known in Arabidopsis.

关键词： Flowering time Brassica rapa Vernalization Photoperiod

Indexing dynamic encrypted database in cloud for efficient secure k-nearest neighbor query

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Frontiers of Computer Science 2024年第1期18卷 187-198页

作者： Xingxin li Youwen ZHU rui XU Jian WANG Yushu ZHANG College of Computer Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 210016China Department of Mathematical Informatics University of TokyoTokyo 113-8654Japan Guangxi Key Laboratory of Trusted Software Guilin University of Electronic TechnologyGuilin 541004China School of Computer Science China University of GeosciencesWuhan 430074China

Secure k-Nearest Neighbor(k-NN)query aims to find k nearest data of a given query from an encrypted database in a cloud server without revealing privacy to the untrusted cloud and has wide applications in many areas,such as privacy-preservingmachine elearning gand secure biometric *** solutions have been put forward to solve this challenging ***,the existing schemes still suffer from various limitations in terms of efficiency and *** this paper,we propose a new encrypt-then-index strategy for the secure k-NN query,which can simultaneously achieve sub-linear search complexity(efficiency)and support dynamical update over the encrypted database(flexibility).Specifically,we propose a novel algorithm to transform the encrypted database and encrypted query points in the *** indexing the transformed database using spatial data structures such as the R-tree index,our strategy enables sub-linear complexity for secure k-NN queries and allows users to dynamically update the encrypted *** the best of our knowledge,the proposed strategy is the first to simultaneously provide these two *** theoretical analysis and extensive experiments,we formally prove the security and demonstrate the efficiency of our scheme.

关键词： cloud computing secure k-NN query sub-linear complexity dynamicupdate

Electrothermal Model Based Remaining Charging Time Prediction of lithium-Ion Batteries against Wide Temperature Range

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Chinese Journal of Mechanical Engineering 2024年第2期37卷 330-339页

作者： rui Xiong Zian Zhao Cheng Chen Xinggang li Weixiang Shen School of Mechanical Engineering Beijing Institute of TechnologyBeijing 100081China School of Science Computing and Engineering TechnologiesSwinburne University of TechnologyHawthornVIC 3122Australia

Battery remaining charging time(RCT)prediction can facilitate charging management and alleviate mileage anxiety for electric vehicles(EVs).Also,it is of great significance to improve EV users’***,the RCT for a lithiumion battery pack in EVs changes with temperature and other battery *** study proposes an electrothermal model-based method to accurately predict battery ***,a characteristic battery cell is adopted to represent the battery pack,thus an equivalent circuit model(ECM)of the characteristic battery cell is established to describe the electrical behaviors of a battery ***,an equivalent thermal model(ETM)of the battery pack is developed by considering the influence of ambient temperature,thermal management,and battery connectors in the battery pack to calculate the temperature which is then fed back to the ECM to realize electrothermal ***,the RCT prediction method is proposed based on the electrothermal model and validated in the wide temperature range from-20℃to 45℃.The experimental results show that the prediction error of the RCT in the whole temperature range is less than 1.5%.

关键词： Electric vehicles lithium-ion batteries Remaining charging time Electrothermal model

Optimizing extractants selection for efficient separation of phenols and nitrogen-containing heteroaromatics using hydrogen bond interaction strategies

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Chinese Journal of Chemical Engineering 2024年第4期68卷 43-52页

作者： Pengzhi Bei rui Zhang Jie Feng Antony Rajendran Wenying li State Key Laboratory of Clean and Efficient Coal Utilization Taiyuan University of TechnologyTaiyuan 030024China Department of Chemistry Mepco Schlenk Engineering College(Autonomous)Sivakasi 626005India

Focusing on the use of imidazolium ionic liquids and quaternary ammonium salts-based deep eutectic solvents for the separation of phenols and nitrogen-containing heteroaromatics,the role of heteroaromatics as specific sites for hydrogen bond-based separation has been *** environmentally friendly solvents are known for their ability to form hydrogen bonds with heteroatoms,a key aspect in separation *** quantified the hydrogen bond interaction energy to reach the threshold energy for efficient O-and N-heteroaromatics *** article provides an in-depth study of the structural nuances of different hydrogen bonding sites and their affinity properties while conducting a comparative evaluation of the separation efficiency of ionic liquids and deep eutectic solvents from a thermodynamic *** showed that phenols with dual hydrogen bonding recognition sites were easier to separate than nitrogen-containing *** ionic liquids were more suitable for the extraction of nonbasic nitrogen-containing heteroaromatics,and quaternary ammonium salts-based deep eutectic solvents are more effective for phenols and basic nitrogen-containing heteroaromatics,which was confirmed by Fourier transform infrared spectroscopy and empirical ***,this study provides a theoretical basis for the strategy design and selection of extractants for the efficient separation of O-and N-containing aromatic compounds.

关键词： Deep eutectic solvents Hydrogen bond Ionic liquids Separation Solvents Structural characteristics

Modeling the Interaction between Vacancies and Grain Boundaries during Ductile Fracture

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 2019-2034页

作者： Mingjian li ping Yang Pengyang Zhao Department of Engineering Mechanics School of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai200240China

The experimental results in previous studies have indicated that during the ductile fracture of pure metals,vacancies aggregate and form voids at grain ***,the physical mechanism underlying this phenomenon remains not fully *** study derives the equilibrium distribution of vacancies analytically by following thermodynamics and the micromechanics of crystal *** derivation suggests that vacancies cluster in regions under hydrostatic compression to minimize the elastic strain ***,a finite element model is developed for examining more general scenarios of interaction between vacancies and grain *** model is first verified and validated through comparison with some available analytical solutions,demonstrating consistency between finite element simulation results and analytical solutions within a specified numerical accuracy.A systematic numerical study is then conducted to investigate the mechanism that might govern the micromechanical interaction between grain boundaries and the profuse vacancies typically generated during plastic *** simulation results indicate that the reduction in total elastic strain energy can indeed drive vacancies toward grain boundaries,potentially facilitating void nucleation in ductile fracture.

关键词： Ductile fracture vacancy grain boundary micromechanical finite element method

Age-specific differences in the association between prediabetes and cardiovascular diseases in China:A national cross-sectional study

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World Journal of Diabetes 2024年第2期15卷 240-250页

作者： Shuo Xie li-ping Yu Fei Chen Yao Wang rui-Fen Deng Xue-lian Zhang Bo Zhang Department of Endocrinology Chinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100730China Department of Endocrinology China-Japan Friendship HospitalBeijing 100029China

BACKGROUND Cardiovascular disease(CVD)is a leading cause of morbidity and mortality worldwide,the global burden of which is *** is still unclear the extent to which prediabetes contributes to the risk of CVD in various age brackets among *** develop a focused screening plan and treatment for Chinese adults with prediabetes,it is crucial to identify variations in the connection between prediabetes and the risk of CVD based on *** To examine the clinical features of prediabetes and identify risk factors for CVD in different age groups in *** The cross-sectional study involved a total of 46239 participants from June 2007 through May 2008.A thorough evaluation was *** with prediabetes were categorized into two groups based on *** atherosclerotic CVD risk prediction model was employed to evaluate the risk of developing CVD over 10 *** forest was established in both age *** Additive exPlanation method prioritized the importance of features from the perspective of assessment *** In total,6948 people were diagnosed with prediabetes in this *** prediabetes,prevalences of CVD were 5(0.29%)in the younger group and 148(2.85%)in the older ***,11.11%of the younger group and 29.59% of the older group were intermediate/high-risk of CVD for prediabetes without CVD based on the Prediction for ASCVD Risk in China equation in ten *** the younger age group,the 10-year risk of CVD was found to be more closely linked to family history of CVD rather than lifestyle,whereas in the older age group,resident status was more closely *** The susceptibility to CVD is age-specific in newly diagnosed *** is necessary to develop targeted approaches for the prevention and management of CVD in adults across various age brackets.

关键词： Age Cardiovascular diseases Prediabetes Risk factors Differences

Biomimetic chitin hydrogel via chemical transformation

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Nano Research 2024年第2期17卷 771-777页

作者： rui-rui liu Qian-Qian Shi Yu-Feng Meng Yong Zhou li-Bo Mao Shu-Hong Yu Division of Nanomaterials&Chemistry Hefei National Research Center for Physical Sciences at the MicroscaleDepartment of ChemistryInstitute of Biomimetic Materials&ChemistryAnhui Engineering Laboratory of Biomimetic MaterialsUniversity of Science and Technology of ChinaHefei 230026China College&Hospital of Stomatology Key Laboratory of Oral Diseases Research of Anhui ProvinceAnhui Medical UniversityHefei 230032China Department of Dental Implantology College&Hospital of StomatologyAnhui Medical UniversityHefei 230032China

Chitin hydrogel has been recognized as a promising material for various biomedical applications because of its biocompatibility and ***,the fabrication of strong chitin hydrogel remains a big challenge because of the insolubility of chitin in many solvents and the reduced chain length of chitin regenerated from *** herein introduce the fabrication of chitin hydrogel with biomimetic structure through the chemical transformation of chitosan,which is a water-soluble deacetylated derivative of *** reacetylation of the amino group in chitosan endows the obtained chitin hydrogel with outstanding resistance to swelling,degradation,extreme temperature and pH conditions,and organic *** chitin hydrogel has excellent mechanical properties while retaining a high water content(more than 95 wt.%).It also shows excellent antifouling performance that it resists the adhesion of proteins,bacteria,blood,and ***,as the initial chitosan solution can be feasibly frozen and templated by ice crystals,the chitin hydrogel structure can be either nacre-like or wood-like depending on the freezing method of the precursory chitosan *** to these anisotropic structures,such chitin hydrogel can exhibit anisotropic mechanics and mass transfer *** current work provides a rational strategy to fabricate chitin hydrogels and paves the way for its practical applications as a superior biomedical material.

关键词： chitin hydrogel biomimetic structure chemical stability mechanical strength antifouling

Microdeletion on Xq27.1 in a Chinese VACTERL-like Family with Kidney and Anal Anomalies

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Biomedical and Environmental Sciences 2024年第5期37卷 503-510页

作者： li Min ZHANG Yu Lan ZHANG Kai li li ping ping LYU Yu Han liANG Ya Xin YU Yue Department of Gynecology and Obstetrics Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing 100730China Chinese Academy of Medical Sciences and Peking Union Medical College Beijing HospitalBeijing 100730China The Key Laboratory of Geriatrics Beijing Institute of GeriatricsBeijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing 100730China

Objective VATER/VACTERL-like association is associated with adverse pregnancy *** evidence of this disorder is *** this study,we aimed to provide genetic insights to improve the diagnosis of *** We have described a Chinese family in which four members were affected by renal defects or agenesis,anal atresia,and anovaginal fistula,which is consistent with the diagnosis of a VACTERL-like *** and genetic analyses were conducted using genome and exome *** Segregation analysis revealed the presence of a recessive X-linked microdeletion in two living affected individuals,harboring a 196–380 kb microdeletion on Xq27.1,which was identified by familial exome *** sequencing was performed on the affected male,confirming a-196 kb microdeletion in Xq27.1,which included a 28%loss of the CDR-1 *** family members were included in the co-segregation analysis,and only VACTERL-like cases with microdeletions were reported in *** These results suggest that the 196–380 kb microdeletion in Xq27.1 could be a possible cause of the VATER/VACTERL-like ***,further genetic and functional analyses are required to confirm or rule out genetic background as the definitive cause of the VACTERL association.

关键词： Prenatal diagnosis VACTERL whole-genome sequencing whole-exome sequencing X-linked

A fully distributed robust optimal control approach for air-conditioning systems considering uncertainties of communication link in IoT-enabled building automation systems

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Energy and Built Environment

Energy and Built Environment 2024年第3期5卷 446-454页

作者： Wenzhuo li rui Tang Shengwei Wang Institute for Environmental Design and Engineering The BartlettUniversity College LondonUK Department of Building Environment and Energy Engineering The Hong Kong Polytechnic UniversityKowloonHong Kong Research Institute for Smart Energy The Hong Kong Polytechnic UniversityKowloonHong Kong

Internet of Things(IoT)technologies are increasingly implemented in buildings as the cost-effective smart sens-ing infrastructure of building automation systems(BASs).They are also dispersed computing resources for novel distributed optimal control ***,wireless communication networks are critical to fulfill these tasks with the performance influenced by inherent uncertainties in networks,e.g.,unpredictable occurrence of link *** and hierarchical distributed approaches are vulnerable against link failure,while the robustness of fully distributed approaches depends on the algorithms *** study therefore proposes a fully distributed robust optimal control approach for air-conditioning systems considering uncertainties of com-munication link in IoT-enabled *** distributed algorithm is adopted that agents know their out-neighbors *** directly coordinate with the connected neighbors for global *** are conducted to test and validate the proposed approach by comparing with existing approaches,i.e.,the centralized,the hierarchical distributed and the fully distributed *** show that different approaches are vulnerable against to uncertainties of communication link to different *** proposed approach always guarantees the optimal control performance under normal conditions and conditions with link failures,verifying its high *** also has low computation complexity and high optimization efficiency,thus applicable on IoT-enabled BASs.

关键词： Multi-agent system Edge computing Air-conditioning system Internet of Things(IoT) Communication link failure