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Reduced graphene oxide as saturable absorbers for erbium-doped passively mode-locked fiber laser

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Chinese Physics B 2018年第8期27卷 1-6页

作者： Zhen-dong Chen Yong-Gang Wang Lu Li rui-dong lv Liang-Lei Wei Si-Cong Liu Jiang Wang and Xi Wang School of Physics and Information Technology Shaanxi Normal UniversityXi'an 710119China School of Science Xi'an Institute of Posts and TelecommunicationsXi'an 710121China State Key Laboratory of Transient Optics and Photonics Xi'an Institute of Optics and Precision MechanicsChinese Academy of SciencesXi'an 710119China

We demonstrate a nanosecond mode-locked erbium-doped fiber laser （EDFL） based on a reduced graphene oxide （RGO） saturable absorber （SA）. The RGO SA is prepared by depositing the graphene oxide （GO） on fluorine mica through thermal reduction of GO. A scanning electron microscope （SEM）, Raman spectrometer, and x-ray photoelectron spec- troscopy （XPS） are adopted to analyze the RGO characteristics. The results show that the reduction degree of graphene oxide is very high. By embedding the RGO SA into the EDFL cavity, a stable mode-locked fiber laser is achieved with a central wavelength of 1567.29 nm and repetition rate of 12.66 MHz. The maximum output power and the minimum pulse duration are measured to be 18.22 mW and 1.38 ns respectively. As far as we know, the maximum output power of 18.22 mW is higher than those of other nanosecond mode-locked oscillators reported. Such a nanosecond pulse duration and megahertz repetition rate make this mode-locked erbium-doped fiber laser a suitable seed oscillator for high-power applications and chirped pulse amplifications.

关键词： fiber lasers mode-locked pulse nonlinear optical materials reduced graphene oxide

Carboxyl graphene oxide solution saturable absorber for femtosecond mode-locked erbium-doped fiber laser

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Chinese Physics B 2018年第11期27卷 517-521页

作者： rui-dong lv Lu Li Yong-gang Wang Zhen-dong Chen Si-cong Liu Xi Wang Jiang wang Yong-fang Li School of Physics and Information Technology Shaanxi Normal University School of Science Xi'an Institute of Posts and Telecommunications State Key Laboratory of Transient Optics and Photonics Xi'an Institute of Optics and Precision MechanicsChinese Academy of Sciences

The carboxyl-functionalized graphene oxide(GO-COOH)is a kind of unique two-dimensional(2 D)material and possesses excellent nonlinear saturable absorption property and high *** this paper,we prepare saturable absorber(SA)device by depositing GO-COOH nanosheets aqueous solution on a D-shaped *** modulation depth(MD)and saturable intensity of the SA are measured to be 9.6%and 19 MW/cm^(2),*** inserting the SA into the erbium-doped fiber(EDF)laser,a passively mode-locked EDF laser has been achieved with the spectrum center wavelength of 1562.76 *** pulse duration,repetition rate,and the signal-to-noise ratio(SNR)are 500 fs,14.79 MHz,and 80 dB,*** maximum average output power is measured to be 3.85 *** results indicate that the GO-COOH nanosheets SA can be used as a promising mode locker for the generation of ultrashort pulses.

关键词： fiber lasers mode-locked pulse nonlinear optical materials carboxyl graphene oxide

Human neural stem cell-derived extracellular vesicles protect against ischemic stroke by activating the PI3K/AKT/mTOR pathway

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Neural Regeneration Research 2025年第11期20卷 3245-3258页

作者： Jiayi Wang Mengke Zhao dong Fu Meina Wang Chao Han Zhongyue lv Liang Wang Jing Liu Stem Cell Clinical Research Center The First Affiliated Hospital of Dalian Medical UniversityDalianLiaoning ProvinceChina Dalian Innovation Institute of Stem Cell and Precision Medicine DalianLiaoning ProvinceChina Institute(College)of Integrative Medicine Dalian Medical UniversityDalianLiaoning ProvinceChina

Human neural stem cell-derived extracellular vesicles exhibit analogous functions to their parental cells,and can thus be used as substitutes for stem cells in stem cell therapy,thereby mitigating the risks of stem cell therapy and advancing the frontiers of stem cell-derived *** lays a foundation for the development of potentially potent new treatment modalities for ischemic ***,the precise mechanisms underlying the efficacy and safety of human neural stem cell-derived extracellular vesicles remain unclear,presenting challenges for clinical *** promote the translation of therapy based on human neural stem cell-derived extracellular vesicles from the bench to the bedside,we conducted a comprehensive preclinical study to evaluate the efficacy and safety of human neural stem cell-derived extracellular vesicles in the treatment of ischemic *** found that administration of human neural stem cell-derived extracellular vesicles to an ischemic stroke rat model reduced the volume of cerebral infarction and promoted functional recovery by alleviating neuronal *** human neural stem cell-derived extracellular vesicles reduced neuronal apoptosis by enhancing phosphorylation of phosphoinositide 3-kinase,mammalian target of rapamycin,and protein kinase B,and these effects were reversed by treatment with a phosphoinositide 3-kinase *** findings suggest that human neural stem cell-derived extracellular vesicles play a neuroprotective role in ischemic stroke through activation of phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin signaling ***,we showed that human neural stem cell-derived extracellular vesicles have a good in vivo safety ***,human neural stem cell-derived extracellular vesicles are a promising potential agent for the treatment of ischemic stroke.

关键词： behavior exosome extracellular vesicles ischemic stroke mammalian target of rapamycin(mTOR) middle cerebral artery occlusion neural stem cells neuronal apoptosis phosphoinositide 3-kinase(PI3K) protein kinase B(AKT)

Blood diagnostic and prognostic biomarkers in amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第9期20卷 2556-2570页

作者： Yongting lv Hongfu Li Department of Neurology Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang ProvinceChina Department of Medical Genetics and Center for Rare disease Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang ProvinceChina Nanhu Brain-Computer Interface Institute HangzhouZhejiang Province

Amyotrophic lateral sclerosis is a devastating neurodegenerative disease for which the current treatment approaches remain severely *** principal pathological alterations of the disease include the selective degeneration of motor neurons in the brain,brainstem,and spinal cord,as well as abnormal protein deposition in the cytoplasm of neurons and glial *** biological markers under extensive scrutiny are predominantly located in the cerebrospinal fluid,blood,and even *** these biomarke rs,neurofilament proteins and glial fibrillary acidic protein most accurately reflect the pathologic changes in the central nervous system,while creatinine and creatine kinase mainly indicate pathological alterations in the peripheral nerves and *** light chain levels serve as an indicator of neuronal axonal injury that remain stable throughout disease progression and are a promising diagnostic and prognostic biomarker with high specificity and ***,there are challenges in using neurofilament light chain to diffe rentiate amyotrophic lateral sclerosis from other central nervous system diseases with axonal *** fibrillary acidic protein predominantly reflects the degree of neuronal demyelination and is linked to non-motor symptoms of amyotrophic lateral sclerosis such as cognitive impairment,oxygen saturation,and the glomerular filtration *** DNA-binding protein 43,a pathological protein associated with amyotrophic lateral sclerosis,is emerging as a promising biomarker,particularly with advancements in exosome-related *** is currently lacking for the value of creatinine and creatine kinase as diagnostic markers;however,they show potential in predicting disease *** the vigorous progress made in the identification of amyotrophic lateral sclerosis biomarkers in recent years,the quest for definitive diagnostic and prognostic biomarke rs remains a formidable *** review summarizes the lat

关键词： amyotrophic lateral sclerosis biomarker blood biomarkers diagnosis glial fibrillary acidic protein neurofilament light chain prognosis TAR DNA-binding protein 43

In situ polymerization of poly(3,4-ethylenedioxythiophene)protective layer towards stable zinc anode

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Nano Research 2025年第1期18卷 382-394页

作者： Debin Luo Peng Zhou Xiaowei lv Panpan Sun Xiaohua Sun Hewei Zhao College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion MaterialsChina Three Gorges UniversityYichang 443002China Hubei Three Gorges Laboratory Yichang 443007China School of Chemistry Beihang UniversityBeijing 100191China

Aqueous zinc-ion devices are considered promising candidates for energy storage due to their high safety,low cost and relatively high energy ***,the dendrite growth,hydrogen evolution reaction(HER)and corrosion of the zinc anode significantly limit the development of Zn-ion ***,an inexpensive poly(3,4-ethylenedioxythiophene)(PEDOT)protective layer was constructed in situ on the Zn surface using electropolymerization to suppress dendrite growth and side reactions,thereby enhancing the reversibility of *** and theoretical calculations revealed that this hydrophilic protective layer promotes the desolvation process of hydrated Zn^(2+)and facilitates the transport of zinc ions,thus improving the thermodynamic and kinetic properties of Zn^(2+)deposition and inhibiting interfacial side ***,the optimized PEDOT@Zn symmetric battery exhibited a cycling stability exceeding 1250 h at 0.5 mA·cm^(-2)and 0.25 mAh·cm^(-2),with a significantly reduced overpotential(from 91.8 to 35 mV).With the assistance of the PEDOT protective layer,the PEDOT@Zn//Cu battery maintained approximately 99.5%Coulombic efficiency after 450 ***-situ scanning electron microscopy(SEM)and in situ optical microscopy characterizations further confirmed that the PEDOT protective layer can effectively suppress the growth of zinc ***,the Zn-ion capacitors assembled by the PEDOT@Zn and activated carbon also demonstrated outstanding cycling stability.

关键词： zinc-ion devices zinc anode poly(3 4-ethylenedioxythiophene)(PEDOT) dendrite desolvation process

The pivotal role of microglia in injury and the prognosis of subarachnoid hemorrhage

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Neural Regeneration Research 2025年第7期20卷 1829-1848页

作者： Wenjing Ning Shi lv Qian Wang Yuzhen Xu Department of Rehabilitation The Second Affiliated Hospital of Shandong First Medical UniversityTaianShandong ProvinceChina Department of Central Laboratory The Affiliated Taian City Central Hospital of Qingdao UniversityTaianShandong ProvinceChina

Subarachnoid hemorrhage leads to a series of pathological changes,including vascular spasm,cellular apoptosis,blood–brain barrier damage,cerebral edema,and white matter ***,which are the key immune cells in the central nervous system,maintain homeostasis in the neural environment,support neurons,mediate apoptosis,participate in immune regulation,and have neuroprotective *** evidence has shown that microglia play a pivotal role in the pathogenesis of subarachnoid hemorrhage and affect the process of injury and the prognosis of subarachnoid ***,microglia play certain neuroprotective roles in the recovery phase of subarachnoid *** approaches aimed at modulating microglia function are believed to attenuate subarachnoid hemorrhage *** provides new targets and ideas for the treatment of subarachnoid ***,an in-depth and comprehensive summary of the role of microglia after subarachnoid hemorrhage is still *** review describes the activation of microglia after subarachnoid hemorrhage and their roles in the pathological processes of vasospasm,neuroinflammation,neuronal apoptosis,blood–brain barrier disruption,cerebral edema,and cerebral white matter *** also discusses the neuroprotective roles of microglia during recovery from subarachnoid hemorrhage and therapeutic advances aimed at modulating microglial function after subarachnoid ***,microglia in subarachnoid hemorrhage are targeted with TLR inhibitors,nuclear factor-κB and STAT3 pathway inhibitors,glycine/tyrosine kinases,NLRP3 signaling pathway inhibitors,Gasdermin D inhibitors,vincristine receptorαreceptor agonists,ferroptosis inhibitors,genetic modification techniques,stem cell therapies,and traditional Chinese ***,most of these are still being evaluated at the laboratory *** clinical studies and data on subarachnoid hemorrhage are required to improve the treatment of subarachnoid hemor

关键词： apoptosis blood–brain barrier brain edema microglia neuroinflammation neuron neuroprotection subarachnoid hemorrhage vasoconstriction white matter injury

Preparation and electrochemical properties of Sn/C composites

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Rare Metals 2019年第10期38卷 996-1002页

作者： Bei-Ping Wang rui lv dong-Sheng Lan School of Materials Science and Engineering North Minzu UniversityYinchuan 750021China School of Materials Science and Engineering Sun Yat-Sen UniversityGuangzhou 510275China

The metal tin(Sn),as one potential anode material for lithium-ion batteries,rapidly degrades its cyclic performance due to huge volume expansion/contraction during lithium intercalation/de-intercalation *** carbon was adopted as conductive and buffer matrix to form Sn/C *** products were prepared by hydrothermal reaction and carbothermal reduction using tin tetrachloride and glucose as raw *** composites were characterized by X-ray diffraction(XRD),Raman spectroscopy,scanning electron microscopy(SEM),transmission electron microscopy(TEM),cyclic voltammetry(CV) and galvanostatic charge/discharge *** results show that relative smaller metallic tin particles in 1:8 Sn/C composite are formed and distributed more uniformly in the carbon *** lithium intercalation capacity of Sn/C composites reaches 820.4 mAh·g-1,and the capacity retention over 60 cycles remains 54.1%.1:8 Sn/C composite exhibits enhanced rate performance and cyclic stability compared to1:5 and 1:10 samples.

关键词： Lithium-ion battery Tin/carbon composite Hydrothermal method Electrochemical performance

Porous sodium titanate nanofibers for high energy quasi-solid-state sodium-ion hybrid capacitors

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Rare Metals 2022年第7期41卷 2453-2459页

作者： Sheng-Yang dong Yu-Lin Wu Nan lv rui-Qi Ren Liang Huang Institute of Advanced Materials and Flexible Electronics(IAMFE) School of Chemistry and Materials ScienceNanjing University of Information Science&TechnologyNanjing 210044China Wuhan National Laboratory for Optoelectronics School of Optical and Electronic InformationHuazhong University of Science and TechnologyWuhan 430074China

Sodium-ion hybrid capacitors(SICs)have considered as promising candidate for lithium-ion counterpart in large-scale energy storage due to their advantages of natural abundance,potential low cost,and high energy-power ... 详细信息

关键词： energy fibers Porous

Decentralized Bilateral Risk-based Self-healing Strategy for Power Distribution Network with Potentials from Central Energy Stations

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Journal of Modern Power Systems and Clean Energy 2023年第1期11卷 179-190页

作者： Chaoxian lv rui Liang Yuanyuan Chai School of Electrical Engineering China University of Mining and TechnologyXuzhouChina School of Electrical Engineering Hebei University of TechnologyTianjinChina

Owing to potential regulation capacities from flexible resources in energy coupling,storage,and consumption links,central energy stations(CESs)can provide additional support to power distribution network(PDN)in case of power ***,existing research has not explicitly revealed the emergency response of PDN with leveraging multiple *** paper proposes a decentralized self-healing strategy of PDN to minimize the entire load loss,in which multi-area CESs’potentials including thermal storage and building thermal inertia,as well as the flexible topology of PDN,are reasonably exploited for service *** sake of privacy preservation,the co-optimization of PDN and CESs is realized in a decentralized manner using adaptive alternating direction method of multipliers(ADMM).Furtherly,bilateral risk management with conditional value-at-risk(CVaR)for PDN and risk constraints for CESs is integrated to deal with uncertainties from outage *** studies are conducted on a modified IEEE 33-bus PDN with multiple *** results illustrate that the proposed strategy can fully utilize the potentials of multi-area CESs for coordinated load *** effectiveness of the performance and behaviors’adaptation against random risks is also validated.

关键词： Power distribution network(PDN) central energy station(CES) bilateral risk management self-healing alternating direction method of multipliers(ADMM)