检索结果-南通市图书馆

Waste Disposal and Sustainable Energy 2024年第2期6卷 173-183页

作者： Yiming li Zhihao Yu Mengyan Guo Ming Zhang Jian Xiong Yina Qiao rui Zhang Xuebin lu School of Environmental Science and Engineering Tianjin UniversityTianjin 30000China School of Ecology and Environment Tibet UniversityLhasa 850000China School of Environment and Safety Engineering North University of ChinaTaiyuan 030051China School of Environmental and Municipal Engineering Tianjin Chengjian UniversityTianjin 300384China

Biomass-based carbon materials with hierarchical porous structures have attracted attention for their ability to provide more channels and shorten ion transport ***,we developed a simple method based on confined nanospace ***-ing high-temperature treatment,the mesoporous silica layer wrapped around the outside of the crab shells acted as a closed nanospace and effectively suppressed the severe deformation of the crab shell structure by shrinking *** prepared carbon material has a layered porous structure with abundant and stable n and O co-doping(n 7.32%,O 3.69%).The specific capacitance of the three-electrode system was 134.3 F/g at a current density of 0.5 A/g in a 6 mol/l KOH electrolyte,and the assembled aqueous symmetric supercapacitors exhibited an excell.nt cycl.ng stability of 98.81%even after 5000 cycles.

关键词： Supercapacitor Confined nanospace deposition Biomass-based carbon materials Crab shell

A COMPACT EMBEDDInG RESUlT FOR nOnlOCAl SOBOlEV SPACES AnD MUlTIPlICITY OF SIGn-CHAnGInG SOlUTIOnS FOR nOnlOCAl SCHRÖDInGER EQUATIOnS

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematica Scientia 2024年第5期44卷 1853-1876页

作者： Xu ZHAnG Hao ZHAI Fukun zhao Department of Mathematics Wuhan University of TechnologyWuhan430070China Department of Mathematics Yunnan Normal UniversityKunming650500China

For any s∈(0,1),let the nonlocal Sobolev space X^(s)(ℝ^(n))be the l.near space of lebesgue measure functions fromℝn toℝsuch that any function u in X^(s)(ℝ^(n))bel.ngs to l2(ℝn)and the function(x,y)\l.ngmapsto\big(u(x)-u(y)\big)\sqrt{K(x-y)}is in l2(ℝn,ℝn).First,we show,for a coercive function V(x),the subspace E:=\bigg\{u\in X^s(\mathbb{R}^n):\int_{\mathbb{R}^n}V(x)u^2{\rm d}xnfty\bigg\}of X^(s)(ℝ^(n))is embedded compactly into l^(p)(ℝ^(n))for p\in[2,2_s^*),where 2_s^*is the fractional Sobolev critical *** terms of applications,the existence of a least energy sign-changing solution and infinitely many sign-changing solutions of the nonlocal Schrödinger equation-{\cal{l}_K}u+V(x)u=f(x,u),\x\in\\mathbb{R}^n are obtained,where-{\cal{l}_K}is an integro-differential operator and V is coercive at infinity.

关键词： sign-changing solution integro-differential operator least energy variational method

瑞巴派特联合法莫替丁治疗早期胃癌术后溃疡患者临床研究

在线全文

学校读者我要写书评

暂无评论

中国临床药理学杂志 2024年第14期40卷 2008-2012页

作者：王锐李多彭昭河北北方学院附属第一医院消化内科河北张家口075100

目的分析瑞巴派特胶囊联合法莫替丁片治疗早期胃癌术后溃疡患者的临床价值。方法选取早期胃癌术后溃疡患者作为研究对象,按照治疗方案用队列法分为对照组和试验组。对照组口服法莫替丁片20 mg,bid;在对照组治疗的基础上,试验组口服瑞巴... 详细信息

目的分析瑞巴派特胶囊联合法莫替丁片治疗早期胃癌术后溃疡患者的临床价值。方法选取早期胃癌术后溃疡患者作为研究对象,按照治疗方案用队列法分为对照组和试验组。对照组口服法莫替丁片20 mg,bid;在对照组治疗的基础上,试验组口服瑞巴派特胶囊0.1 g,tid,2组均持续治疗4周。对比2组患者胃黏膜形态学指标、胃肠激素[血管活性肠肽(VIP)、胆囊收缩素(CCK)、胃动素(MTl)]、胃蛋白酶原[胃蛋白酶原Ⅰ(PG I)、胃蛋白酶原Ⅱ(PGⅡ)]。结果对照组和试验组各入组40例。治疗后,试验组的总有效率92.50%(37例/40例)较对照组高[75.00%(30例/40例)],在统计学上差异有统计学意义(Png·l^(-1),CCK分别为(55.38±58.47)和(71.48±10.38)ng·l^(-1),MTl分别为(82.19±14.52)和(97.68±11.58)pg·ml^(-1),PG I分别为(168.74±17.42)和(136.78±15.44)ng·ml^(-1),PGⅡ分别为(16.42±2.50)和(20.58±3.79)ng·ml^(-1),试验组的上述指标与对照组比较,在统计学上差异均有统计学意义(均P0.05)。结论瑞巴派特胶囊联合法莫替丁片治疗早期胃癌术后溃疡患者有效性和安全性佳,可改善患者胃黏膜形态学指标、胃肠激素及胃蛋白酶原。

关键词：瑞巴派特胶囊法莫替丁片胃溃疡早期胃癌术后

n-cycle gene abundance determination of n mineralization rate following re-afforestation in the loess Plateau of China

在线全文

学校读者我要写书评

暂无评论

Soil Ecology letters 2024年第1期6卷 97-106页

作者： Yaping zhao Yuqing zhao Shuohong Zhang Yul.n Xu Xinhui Han Gaihe Yang Chengjie Ren College of Agronomy Northwest A&F UniversityYangling 712100China Shaanxi Engineering Research Center of Circular Agriculture College of AgronomyNorthwest A&F UniversityYangling 712100China

Afforestation effectively improved soil microbial communities and significantly increased soil.nitro-gen mineralization rate(Rm).Soil microorganisms drive Rm by regulating soil.n-cycl.ng *** nitrification genes had a major effect on soil Rm than denitrification genes after *** the function of forest ecosystems requires an understanding of the mechanism of soil.nitrogen ***,it remains unclear how soil.n-cycl.ng genes drive soil.nitrogen mineralization during *** this study,we collected soil samples from a chrono-sequence of 14,20,30,and 45 years of Robinia pseudoacacia l.(RP14,RP20,RP30,and RP45)with a sloped farml.nd(Fl)as a *** metagenomic sequencing analysis,we found significant changes in the diversity and composition of soil microbial communities involved in n-cycl.ng al.ng the afforestation time series,with afforestation effectively increasing the diversity(both alpha and beta diversity)of soil microbial *** conducted indoor culture experiments and analyzed correlations,which revealed a significant increase in both soil.nitrification rate(Rn)and soil.nitrogen mineralization rate(Rm)with increasing stand ***,we found a strong correlation between soil Rm and soil microbial diversity(both alpha and beta diversity)and with the abundance of soil.n-cycl.ng *** least squares path model.ng(PlS-PM)analysis showed that nitrification genes(narH,narY,nxrB,narG,narZ,nxrA,hao,pmoC-amoC)and denitrification genes(norB,nosZ,nirK)had a greater direct effect on soil Rm compared to their effect on soil microbial *** results reveal the relationships between soil.nitrogen mineralization rate and soil microbial communities and between the mineralization rate and functional genes involved in n-cycl.ng,in the context of Robinia pseudoacacia *** on the loess *** study enriches the understanding of the effects of microorganisms on soil.nitrogen mineraliza

关键词： afforestation soil.n mineralization rate denitrification genes nitrification genes the loess Plateau

Enhancing single-cell encapsulation in droplet microfluidics with fine-tunable on-chip sample enrichment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Microsystems & nanoengineering 2024年第1期10卷 149-160页

作者： Tao Tang Hao zhao Shaofei Shen like Yang Chwee Teck lim Department of Biomedical Engineering National University of Singapore117583 SingaporeSingapore Integrative Sciences and Engineering Programme NUS Graduate SchoolNational University of Singapore119077 SingaporeSingapore Shanxi Key lab for Modernization of TCVM College of Life ScienceShanxi Agricultural UniversityTaiguShanxi 030801China Institute for Health Innovation&Technology National University of Singapore117599 SingaporeSingapore Mechanobiology Institute National University of Singapore117411 SingaporeSingapore Institute for Digital Molecular Analytics and Science Nanyang Technological University636921 SingaporeSingapore

Single-cell encapsulation in droplet microfluidics is commonly hindered by the tradeoff between cell suspension density and on-chip focusing *** this study,we introduce a novel droplet microfluidic chip to overcome this *** chip comprises a double spiral focusing unit,a flow resistance-based sample enrichment module with fine-tunable outlets,and a crossflow droplet generation *** a low-density cell/bead suspension(2×10^(6) objects/ml),cells/beads are focused into a near-equidistant l.near arrangement within the double spiral *** excess water phase is diverted while cells/beads remain focused and sequentially encapsulated in individual *** performance was assessed through numerical simulations and experiments at three flow rates(40,60,80μl/min),demonstrating successful focusing at 40 and 80μl/min for beads and cells,*** addition,both simulation and experimental results revealed that the flow resistance at the sample enrichment module is adjustable by punching different outlets,allowing over 50%of the aqueous phase to be ***8n-based droplet detection algorithms realized the counting of cells/beads in droplets,statistically demonstrating single-cell and bead encapsulation rates of 72.2%and 79.2%,*** the results indicate that this on-chip sample enrichment approach can be further developed and employed as a critical component in single-cell encapsulation in water-in-oil droplets.

关键词： beads outlet sample

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

土壤盐胁迫对紫花苜蓿磷素利用的影响

水土保持学报 2024年第2期38卷 414-422页

作者：赵乐苏睿何红花西北农林科技大学资源环境学院陕西杨凌712100 平凉市环境工程评估中心甘肃平凉744000 中国科学院水利部水土保持研究所黄土高原土壤侵蚀与旱地农业国家重点实验室陕西杨凌712100

[目的]为了研究土壤磷肥和盐分及其交互作用对紫花苜蓿生长、磷营养和耐盐性的影响。[方法]通过向[土娄]土中添加不同浓度梯度的磷肥(0,40,80,160mg/kg,以KH_(2)PO_(4)的形式添加)和氯化钠(0,0.4,0.8,1.6g/kg)进行温室盆栽试验,种植紫... 详细信息

[目的]为了研究土壤磷肥和盐分及其交互作用对紫花苜蓿生长、磷营养和耐盐性的影响。[方法]通过向[土娄]土中添加不同浓度梯度的磷肥(0,40,80,160mg/kg,以KH_(2)PO_(4)的形式添加)和氯化钠(0,0.4,0.8,1.6g/kg)进行温室盆栽试验,种植紫花苜蓿“甘农七号”。[结果]紫花苜蓿地上部生物量和地下部生物量均随着磷肥施加水平的提高而增加,但随着盐分添加水平的提高而减少;施磷时植物的磷吸收量增加,当磷水平为160mg/kg时,根、茎、叶的磷含量均达到最大。添加盐分抑制对磷的吸收,当盐水平为1.6g/kg时,根、茎、叶的磷含量与不加naCl时相比显著减少;与不加磷肥时相比,酒石酸含量随着磷肥水平升高而减少,外源盐分添加显著增加紫花苜蓿根际酒石酸的含量;大部分处理的根际pH与非根际pH相比均降低,在盐胁迫的情况下土壤pH的降低提高土壤磷的有效性和植物对磷的吸收;高剂量(160mg/kg)的磷肥添加使紫花苜蓿的磷吸收效率、磷利用效率均显著降低。[结论]土壤磷肥与盐分之间存在显著的交互作用,盐分增加加剧植物磷缺乏,适当施用磷肥可提高紫花苜蓿的耐盐性,并提高其在盐渍土壤中的生产力。

关键词：紫花苜蓿磷有效性盐分磷吸收效率根际酒石酸

RnA m^(6)A reader YTHDF2 facilitates precursor miR-126 maturation to promote acute myeloid leukemia progression

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第1期11卷 382-396页

作者： Zheng Zhang Keren Zhou li Han Andrew Small Jianhuang Xue Huil.n Huang Hengyou Weng rui Su Brandon Tan Chao Shen Wei li Zhicong zhao Ying Qing Xi Qin Kitty Wang Keith leung Mark Boldin Chun-Wei Chen David Ann Zhijian Qian Xiaol.n Deng Jianjun Chen Zhenhua Chen Department of Systems Biology Beckman Research Institute of City of HopeMonroviaCA 91016USA Irell and Manella Graduate School of Biological Sciences Beckman Research Institute of City of HopeDuarteCA 91010USA Gehr Family Center for leukemia Research City of HopeDuarteCA 91010USA Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangzhouGuangdong 510060China Guangzhou laboratory GuangzhouGuangdong 510005China Biol.nd laboratory GuangzhouGuangdong 51005China Department of liver Surgery Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China Department of Diabetes Complications and Metabolism Beckman Research Institute of City of HopeDuarteCA 91010USA Department of Biochemistry and Molecular Biology University of FloridaGainesvilleFL 32603USA Tongji Hospital Affiliated to Tongji University Frontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China School of Pharmacy China Medical UniversityShenyangLiaoning 110001China

As the most common internal modification of mRnA,ne-methyladenosine(m^(6)A)and its regulators modulate gene expression and play critical roles in various biological and patholog-ical processes including *** was reported previously that m^(6)A methyltransferase(writer),methyltransferase-like 3(METTl3)adds m^(6)A in primary microRnAs(pri-miRnAs)and fa-cilitates its processing into precursor miRnAs(pre-miRnAs).However,it is unknown whether m^(6)A modification also plays a role in the maturation process of pre-miRnAs and(if so)whether such a function contributes to ***,we found that YTHDF2 is aberrantly overexpressed in acute myeloid leukemia(AMl)patients,especially in relapsed patients,and plays an onco-genic role in ***,YTHDF2 promotes expression of miR-126-3p(also known as miR-126,as it is the main product of precursor miR-126(pre-miR-126)),a miRnA that was reported as an oncomiRnA in AMl,through facilitating the processing of pre-miR-126 into mature ***,YTHDF2 recognizes m^(6)A modification in pre-miR-126 and recruits AGO2,a regulator of pre-miRnA processing,to promote the maturation of ***2 posi-tively and negatively correlates with miR-126 and miR-126's downstream target genes,respec-tively,in AMl patients,and forced expression of miR-126 could largely rescue YTHDF2/Ythdf2 depletion-mediated suppression on AMl cell growth/proliferation and leukemogenesis,indi-cating that miR-126 is a functionally important target of YTHDF2 in ***,our studies not only reveal a previously unappreciated YTHDF2/miR-126 axis in AMl and highlight the ther-apeutic potential of targeting this axis for AMl treatment,but also suggest that m^(6)A plays a role in pre-miRnA processing that contributes to tumorigenesis.

关键词： AMl miR-126 n^(6)-methyladenosine Pre-miRnA maturation YTHDF2

Facile synthesis of magnetic coval.nt organic framework nanocomposites for the enrichment and quantification of trace organophosphorus pesticides in fruit juice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wel.ness 2024年

作者： Quanbin Fu Xin Sun lu liu Hail.ng Jiang Geoffrey I.n.Waterhouse Shiyun Ai Rusong zhao School of Chemical Sciences， The University of Auckl.nd College of Chemistry and Material Science， Shandong Agricultural University Qilu University of Technology (Shandong Academy of Sciences)， Shandong Analysis and Test Center， Key laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province College of Food Science and Engineering， Shandong Agricultural University

Organophosphorus pesticides (OPPs) in foods pose a serious threat to human health， motivating the development of novel analytical methods for their rapid detection and quantification. A magnetic coval.nt organic framework (M-COF) adsorbent for the magnetic solid-phase extraction (MSPE) of OPPs from foods was reported. M-COF was synthesized by the Schiff base condensation reaction of 1，3，5-tris (4-aminophenyl)benzene and 4，4-biphenyldicarboxaldehyde on the surface of amino-functionalized magnetic nanoparticles. Density–functional theory (DFT) calculations showed that adsorption of OPPs onto the surface of M-COF involved hydrophobic effects， Van der Waals interactions， π–π interactions， halogen-n bonding， and hydrogen bonding. Combined with gas chromatography–mass spectrometry (GC–MS) technology， the MSPE method features low limits of detection for OPPs (0.002–0.015 μg/l)， good reproducibility (1.45%–6.14%)， wide l.near detection range (0.01–1 μg/l， R≥ 0.9935)， and satisfactory recoveries (87.3%–110.4%). The method was successfully applied for the trace analysis of OPPs in spiked fruit juices.

关键词：

The effect of fasting plasma glucose on in-hospital mortality after acute myocardial infarction in patients with and without diabetes:findings from a prospective,nationwide,and multicenter registry

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2024年第5期21卷 523-533页

作者： rui FU Ying-Xuan ZHU Kong-Yong CUI Jin-Gang YAnG Hai-Yan XU Dong YIn Wei-Hua SOnG Hong-Jian WAnG Cheng-Gang ZHU lei FEnG Wei WU Kai-HongCHEn Yan-Yan zhao Ye lU Ke-Fei DOU Yue-Jin YAnG on behalf of the CAMI Registry Investigators Cardiometabolic Medicine Center Fuwai HospitalNational Center for Cardiovascular DiseasesState Key Laboratory of Cardiovascular DiseaseNational Clinical Research Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Medical Research&Biometrics Center Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Coronary Heart Disease Center Fuwai HospitalNational Center for Cardiovascular DiseasesState Key Laboratory of Cardiovascular DiseaseNational Clinical Research Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Cardiology Guangzhou Traditional Chinese Medical College First Affiliated HospitalGuangdong ProvinceChina Department of Cardiology Longyan Hospital First HospitalFujian ProvinceChina 不详

OBJECTIVES To evaluate the predictive value of fasting plasma glucose(FPG)for in-hospital mortality in patients with acute myocardial infarction(AMI)with different glucose metabolism *** We selected 5,308 participants with AMI from the prospective,nationwide,multicenter CAMI registry,of which 2,081 were diabetic and 3,227 were *** were divided into high FPG and low FPG groups according to the optim-al cutoff values of FPG to predict in-hospital mortality for diabetic and nondiabetic cohorts,*** primary endpoint was in-hospital *** Overall,94 diabetic patients(4.5%)and 131 nondiabetic patients(4.1%)died during hospitalization,and the optimal FPG thresholds for predicting in-hospital death of the two cohorts were 13.2 mmol/l and 6.4 mmol/l,*** with individuals who had low FPG,those with high FPG were significantly associated with higher in-hospital mortality in diabet-ic cohort(10.1%vs.2.8%;odds ratio[OR]=3.862,95%confidence interval[CI]:2.542-5.869)and nondiabetic cohort(7.4%vs.1.7%;HR=4.542,95%CI:3.041-6.782).After adjusting the potential confounders,this significant association was not ***-more,FPG as a continuous variable was positively associated with in-hospital mortality in single-variable and multivariable models regardless of diabetic *** FPG to the original model showed a significant improvement in C-statistic and net reclassification in diabetic and nondiabetic *** This large-scale registry indicated that there is a strong positive association between FPG and in-hospital mor-tality in AMI patients with and without *** might be useful to stratify patients with AMI.

关键词： patients fasting infarction

酰胺和咪唑基离子液体双极性基团共嵌入式亲水C18硅胶固定相的制备与应用

在线全文

学校读者我要写书评

暂无评论

高等学校化学学报 2024年第4期45卷 19-28页

作者：陈贝怡观文娜靳钊刘婷婷周睿青岛科技大学高分子科学与工程学院青岛266045 中国科学院青岛生物能源与过程研究所青岛266101

利用分步键合法制备了酰胺和咪唑基离子液体双极性基团共嵌入的十八烷基修饰硅胶色谱固定相,并通过离子交换制备了2种具有不同阴离子配位的固定相(Sil-Il-AMC18-Cl和Sil-Il-AMC18-Tf2n).采用红外光谱和元素分析对2种固定相进行了表征,... 详细信息

利用分步键合法制备了酰胺和咪唑基离子液体双极性基团共嵌入的十八烷基修饰硅胶色谱固定相,并通过离子交换制备了2种具有不同阴离子配位的固定相(Sil-Il-AMC18-Cl和Sil-Il-AMC18-Tf2n).采用红外光谱和元素分析对2种固定相进行了表征,发现红外光谱中均在1460和661 cm^(-1)处出现了咪唑环上C=C的伸缩振动峰和C=n的弯曲振动峰,在2927和2856 cm^(-1)处出现了─CH的不对称和对称伸缩振动峰,证明氨基咪唑离子液体键合成功;而原有919 cm^(-1)处的伯胺n─H面外变形振动峰消失,说明十八烷基酰氯与氨基已键合.元素分析结果表明,Sil-Il-AMC18-Cl的氮元素含量为3.07%,碳元素含量为16.73%,氢元素含量为3.07%,Sil-Il-AMC18-Tf2n的氮元素含量为2.88%,碳元素含量为15.98%,氢元素含量为2.95%,说明确已制得Sil-IlAMC18-Cl和Sil-Il-AMC18-Tf2n色谱固定相.考察了2种固定相的色谱分离模式与分离性能,结果表明:(1)在反相色谱模式(RPlC)下,相较于商品化C18色谱柱,两种固定相均具有更高的柱效;(2)由于具有双极性基团,相较于传统亲水改性C18硅胶固定相具有更强的亲水能力,因此可以实现亲水色谱模式(HIlIC);(3)在反相/亲水(RPlC/HIlIC)混合色谱模式下,可同时分离亲水性和疏水性物质.通过考察发现,Sil-Il-AMC18-Cl固定相比Sil-Il-AMC18-Tf2n固定相有更强的亲水性能,因此在HIlIC色谱模式下将Sil-Il-AMC18-Cl固定相应用于8种碱基核苷类物质的分离,可实现该类强亲水性物质的基线分离,进样重复性RSD=0.03%~0.25%(n=9);在RPlC色谱模式下将Sil-Il-AMC18-Tf2n固定相应用于6种苯胺类物质的分离,不仅可以实现基线分离,而且可明显改善苯胺类物质的峰拖尾现象,进样重复性RSD=0.05%~0.10%(n=9).

关键词：亲水改性C18硅胶填料混合模式液相色谱固定相碱基核苷苯胺