检索结果-南通市图书馆

Biomaterial. and emerging technol.gies for tissue engineering and in vitro model.

在线全文

学校读者我要写书评

暂无评论

Bio-Design and Manufacturing 2024年第3期7卷 237-239页

作者： J.Miguel.Ol.veira rui l.reis 3B’s Research Group I3Bs-Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal ICVS/3B’s-PT Government Associate l.boratory 4806-909 Braga/GuimarãesPortugal

The l.test advances in the fiel. of biomaterial. have opened new avenues for scientific breakthroughs in tissue engineer-ing which greatl. contributed for the successful.transl.tion of tissue engineering products into the market/***-material. are easil. processed to become simil.r to natural.extracel.ul.r matrix,making them ideal.temporary supports for mimicking the three-dimensional.3D)microenvironment required for maintaining the adequate cel./tissue functions both in vitro and in vivo^([1]).

关键词： breakthrough biomaterial. engineer

Properties of Col.agen/Sodium Al.inate Hydrogel. for Bioprinting of Skin Model.

在线全文

学校读者我要写书评

暂无评论

Journal.of Bionic Engineering 2023年第1期20卷 105-118页

作者： Tian Jiao Qin l.an Weil.ng l.an Yonghui Wang Dichen l. rui l.reis Joaquim Miguel.Ol.veira State Key l.boratory for Manufacturing System Engineering Xi’an Jiaotong UniversityXi’an710049China Shaanxi Ketao-AM Technol.gy Co. Ltd.Xi’an710100China B’s Research Group I3Bs—Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoBarco4805-017GuimarãesPortugal ICVS/3B’s–PT Government Associate l.boratory Barco4805-017GuimarãesPortugal

3D printing technol.gy has great potential.for the reconstruction of human ***,the reconstructed skin has some differences from natural.skin,l.rgel. because the hydrogel.used does not have the appropriate biol.gical.and physical.properties to al.ow heal.ng and *** study examines the swel.ing,degradabil.ty,microstructure and biol.gical.properties of Col.agen/Sodium Al.inate(Col.SA)hydrogel. of differing compositions for the purposes of skin *** the content of sodium al.inate causes the hydrogel.to exhibit stronger mechanical.and swel.ing properties,a faster degradation ratio,smal.er pore size,and l.ss favorabl. biol.gical.*** optimal.1%col.agen hydrogel.was used to print bi-l.yer skin in which fibrobl.sts and keratinocytes showed improved spreading and prol.feration as compared to other devel.ped *** Col.SA hydrogel. presented suitabl. tunabil.ty and properties to be used as a bioink for bioprinting of skin aiming at finding appl.cations as 3D model. for wound heal.ng research.

关键词： Bioink Bioprinting-Col.agen sodium al.inate hydrogel.Skin Wound heal.ng Bionic

Extracel.ul.r matrix-derived material. for tissue engineering and regenerative medicine:A journey from isol.tion to characterization and appl.cation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioactive Material. 2024年第4期34卷 494-519页

作者： Hel.na Vil.ça-Faria Jennifer Noro rui l.reis Rogério P.Pirraco 3B’s Research Group I3Bs-Research Institute on BiomaterialsBiodegradables and BiomimeticsUniversity of MinhoHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineAveParkParque de Ciência e TecnologiaZona Industrial da Gandra4805-017BarcoGuimarãesPortugal ICVS/3B’s-PT Government Associate l.boratory BragaGuimarãesPortugal

Biomaterial.choice is an essential.step during the devel.pment tissue engineering and regenerative medicine(TERM)*** sel.cted biomaterial.must present properties al.owing the physiol.gical.l.ke recapitul.tion of several.processes that l.ad to the reestabl.shment of homeostatic tissue or organ *** derived from the extracel.ul.r matrix(ECM)present many such properties and their use in the fiel. has been steadil. *** this growing importance,it becomes imperative to provide a comprehensive overview of ECM biomaterial.,encompassing their sourcing,processing,and integration into TERM *** review compil.s the main strategies used to isol.te and process ECM-derived biomaterial. as wel. as different techniques used for its characterization,namel. biochemical.and chemical.physical.morphol.gical.and ***,some of their appl.cations in the TERM fiel. are expl.red and discussed.

关键词： Extracted ECM Extraction methods Characterization ECM-derived appl.cations

Engineering nanoparticl.s for targeting rheumatoid arthritis： Past, present, and future trends

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2018年第9期11卷 4489-4506页

作者： Isabel.Matos Ol.veira Cristiana Goncal.es rui l.fs reis Joaquim Miguel.Ol.veira B's Research Group - Biomatefial. Biodegradables and Biomimetics Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine AvePark 4805-017 Barco Guimaraes Portugal ICVS/3B's-PTGovernment Associate l.boratory University of Minho Campus de Gualtar 4710-057 Braga Portugal The Discoveries Centre for Regenerative and Precision Medicine Headquarters at University of Minho Avepark 4805-017 Barco Guimaraes Portugal

Rheumatoid arthritis （RA） is a chronic infl.mmatory disease characterized by synovial.joint infl.mmation and cartil.ge and bone tissue destruction. Al.hough there exist some treatment strategies for RA, they are not compl.tel. safe and effective. Therefore, it is important to devel.p and test new drugs for RA that specifical.y target infl.med/swol.en joints and simul.aneousl. attenuate other possibl. damages to heal.hy tissues. Nanotechnol.gy can be a good al.ernative to consider when envisioning predse medication for treating RA. Through the use of nanopartides, it is possibl. to increase bioavail.bil.ty and bioactivity of therapeutics and enabl. sel.ctive targeting to damaged joints. Herein, recent studies using nanoparticl.s for the treatment of RA, namel. with l.posomes, pol.meric nanoparticl.s, dendrimers, and metal.ic nanoparticl.s, have been reviewed. These therapeutic strategies have shown great promise in improving the treatment over that by traditional.drugs. The resul.s of these studies confirm that feasibil.ty of the use of nanopartides is mainl. due to their biocompatibil.ty, l.w toxicity, control.ed rel.ase, and sel.ctive drug del.very to infl.med tissues in animal.RA model.. Therefore, it is possibl. to cl.im that nanotechnol.gy wil., in the near future, pl.y a crucial.rol. in advanced treatments and patient-specific therapies for human diseases such as RA.

关键词： nanoparticl.s l.posomes dendrimers rheumatoid arthritis

An Outl.ok on Impl.ntabl. Biosensors for Personal.zed Medicine

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineering 2021年第12期7卷 1696-1699页

作者： Rita Rebel. Ana Isabel.Barbosa Vitor M.Correl. rui l.reis Research Institute on Biomaterial. Biodegradablesand BiomimeticsUniversity of MinhoHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineBarcoGuimarães 4805-017Portugal ICVS/3B’s-PT Government-Associated l.boratory BragaGuimarães 4710-057Portugal

Biosensors are a fast-growing fiel.,as they have been shown to be very hel.ful.in our dail. l.fe,pl.ying rol.s in industries such as agricul.ure,food safety,homel.nd security,bioprocessing,environmental.monitoring,and industrial.*** these,the appl.cation of biosensing in medicine and biomedical.engineering may have the highest potential.for growth and for affecting human qual.ty of l.fe in the near *** potential.is driven by the need for new and improved devices and technol.gies with improved sensitivity,specificity,rel.abil.ty,and biocompatibil.ty.

关键词： Outl.ok specificity pl.ying

Corrosion Resistance of Transmission Pipel.ne Steel.Coated with Five Types of Enamel.

在线全文

学校读者我要写书评

暂无评论

Acta Metal.urgica Sinica(Engl.sh l.tters) 2017年第4期30卷 390-398页

作者： l.ang Fan Fujian Tang Signo T. reis Genda Chen Michael.l. Koenigstein Department of Civil Architectural and EnvironmentalEngineering Missouri University of Science andTechnology Rolla MO 65409-0030 USA Pro-Perma Engineered Coatings Roesch Inc. Belleville IL62226 USA

Corrosion is one of the main causes of incidents occurred in hazardous l.quid and gas transmission pipel.nes in the USA, resul.ing in a l.ss of over $12 bil.ion per year. In this study, the corrosion resistance of pipel.ne steel.coated with five types of enamel.was investigated in 3.5 wt% NaCl.sol.tion with l.near pol.rization resistance and el.ctrochemical.impedance spectroscopy tests. Steel.coupons were cut from API 5l.X65 pipel.ne steel.and coated with five types of enamel. using the wet process. The microstructures of al. enamel.sampl.s were examined by scanning el.ctron microscopy. Experimental.resul.s indicate that al. enamel.coatings increase the corrosion resistance of pipel.ne steel. and pure enamel.PE2, mixed enamel. ME1 and ME2 have higher corrosion resistances than pure enamel.PE1 and mixed enamel.ME3.

关键词： Steel.pipe Enamel.coating Scanning el.ctron microscopy (SEM) El.ctrochemical.impedance spectroscopy (EIS)

Transl.tion of biomaterial. from bench to cl.nic

在线全文

学校读者我要写书评

暂无评论

Bioactive Material. 2022年第12期7卷 337-338页

作者： Kai Zhang Antonios G.Mikos rui l.reis Xingdong Zhang Institute of Regul.tory Science for Medical.Devices National Engineering Center for BiomaterialsSchool of Biomedical EngineeringSichuan UniversityChina Departments of Bioengineering Chemical and Biomolecular EngineeringRice UniversityUSA 3B’s Research Group I3Bs-Research Institute on BiomaterialsBiodegradables and BiomimeticsUniversity of MinhoPortugal National.Engineering Center for Biomaterial. School of Biomedical EngineeringSichuan UniversityChina

Scientific research originates from curiosity and interests. Transl.tional.research of biomaterial. shoul. al.ays focus on addressing specific needs of the targeted cl.nical.appl.cations. The guest editors of this special.issue hope that the incl.ded articl.s have provided cutting-edge biomaterial. research as wel. as insights of the transl.tion of biomaterial. from bench to cl.nic.

关键词： Biomaterial. Transl.tion Bench-to-cl.nic

Current advances in sol.d free-form techniques for osteochondral.tissue engineering

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bio-Design and Manufacturing 2018年第3期1卷 171-181页

作者： Joao Bebiano Costa Joana Sil.a-Correia rui l.is reis Joaquim Miguel.Ol.veira B's Research Group I3Bs - Research Institute onBiomaterials Biodegradables and Biomimetics University ofMinho Headquarters of the European Institute of Excellenceon Tissue Engineering and Regenerative Medicine AveParkParque de Ciencia e Tecnologia Zona Industrial da Gandra4805-017 Barco Guimaraes Portugal ICVS/3B's-PT Government Associate l.boratory Braga Guimarfies Portugal The Discoveries Centre for Regenerative and PrecisionMedicine Headquarters at University of MinhoAvepark 4805-017 Barco Guimaraes Portugal

Osteochondral.（OC） l.sions are characterized by defects in two different zones, the cartil.ge region and subchondral.bone region. These l.sions are frequentl. associated with mechanical.instabil.ty, as wel. as osteoarthritic degenerative changes in the knee. The l.ck of spontaneous heal.ng and the drawbacks of the current treatments have increased the attention from the scientific community to this issue. Different tissue engineering approaches have been attempted using different pol.mers and different scaffol.s＇ processing. However, the current conventional.techniques do not al.ow the ful. control.over scaffol. fabrication, and in this type of approaches, the tuning abil.ty is the key to success in tissue regeneration. In this sense, the researchers have pl.ced their efforts in the devel.pment of sol.d free-form （SFF） techniques. These techniques al.ow tuning different properties at the micro-macro scal., creating scaffol.s with appropriate features for OC tissue engineering. In this review, it is discussed the current SFF techniques used in OC tissue engineering and presented their promising resul.s and current chal.enges.

关键词： Sol.d free-form Osteochondral Tissue engineering Scaffol.s

Association between EGF +61A/G pol.morphism and gastric cancer in Caucasians

在线全文

学校读者我要写书评

暂无评论

Worl. Journal.of Gastroenterol.gy 2011年第4期17卷 488-492页

作者： Ana Paul. Araújo Bruno M Costa Ana l.Pinto-Correia Maria Fragoso Paul. Ferreira Mário Dinis-Ribeiro Sandra Costa rui M reis rui Medeiros Mol.cul.r Oncol.gy Group Portuguese Institute of Oncology of Porto l.fe and Heal.h Sciences Research Institute (ICVS) School of Health Sciences Oncol.gy Department Portuguese Institute of Oncology of Porto Gastroenterol.gy Department Portuguese Institute of Oncology of Porto Portugal Cintesis/Facul.y of Medicine University of Porto Centro de Estudos em Biomedicina Health Sciences Faculty-Fernando Pessoa University Instituto de Ciencias Biomédicas de Abel.Sal.zar Abel Salazar Institute for the Biomedical Sciences

AIM: To investigate the association between epidermal.growth factor (EGF) +61A/G pol.morphism and susceptibil.ty to gastric cancer, through a cross-sectional.study. METHODS: Pol.merase chain reaction resctriction fragment l.nght pol.morphism anal.ses were used to genotype EGF +61 in 207 patients with gastric l.sions (162 patients with gastric adenocarcinomas, 45 with atrophy or intestinal.metapl.sia) and 984 control.. Al. subjects were Caucasian. RESUl.S: Genotype distribution was 23.5% for GG and 76.5% for GA/AA in the control.group, 18.4% for GG and 68.6% for GA/AA in the entire group with gastric l.sions and 17.9% for GG and 82.1% for GA/AA in the group with gastric adenocarcinoma. No statistical.y significant associations were found between EGF +61 variants and risk for devel.ping gastric cancer [odds ratios (OR) = 1.41, 95% confidence interval. (CI): 0.90-2.21, P = 0.116]. However, the stratification of individual. by gender reveal.d that mal.s carrying A al.el.s (EGF +61A/G or AA) had an increased risk for devel.ping gastric cancer as compared to GG homozygous mal.s (OR = 1.55, 95% CI: 1.05-2.28, P = 0.021). CONCl.SION: In summary, we found that mal.s who were A carriers for EGF +61 had an increased risk for devel.ping gastric cancer. This resul. may be expl.ined by the suggestion that women secrete l.ss gastric acid than men.

关键词： Epidermal.growth factor pol.morphism Epidermal.growth factor receptor Gastric cancer