检索结果-南通市图书馆

Experimental Hyperthermia during Cardiac Arrest and CPR Is Associated with Severe Spontaneous Hypothermia in Mice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neuroscience & Medicine 2012年第3期3卷 306-313页

作者： ruediger R. Noppens Julia Kofler Richard Traystman Department of Anesthesiology Medical Center of the Johannes Gutenberg University Mainz Germany Department of Pathology University of Pittsburgh Pittsburgh USA University of Colorado Denver Anschutz Medical Center Colorado USA

Background: Since genetically engineered mice are becoming more and more available, these animals become of high interest to study physiologic and pathophysiologic pathways of brain ischemia. The aim of this study was to examine body temperature (Tb), physical activity variation and neurohistopathology in mice exposed to normothermic and hyperthermic cardiac arrest and cardiopulmonary resuscitation (CA/CPR). Methods: Male C57Bl/6 mice weighing 22 - 27 g were implanted intraperitoneally with a radio telemeter and subjected to 10 min cardiac arrest followed by cardiopulmonary resuscitation. Normothermia (37.5°C) or hyperthermia (39.0°C) was induced by controlling pericranial temperature during the arrest period. Results: Hyperthermia during the arrest resulted in a Tb decrease during early recovery to a nadir of 28°C ± 0.8°C (mean ± SE) and partially recovered to 34.4°C ± 1°C 36 hrs after CA/CPR. With normothermia during the arrest, Tb depression was less pronounced (nadir of 32.3°C ± 0.3°C) and recovered to physiologic levels within 24 hrs. Coupling of physical activity and body temperature was absent in all animals after CA/CPR. Neuronal injury in the caudoputamen was greater in the hyperthermia group. Conclusions: This study demonstrates that CA/CPR eliminates normal connectivity between body temperature and physical activity and induces long-lasting hypothermia, the depth of which is related to severity of brain injury. Long term temperature monitoring is required in survival murine experiments, if body temperature is a study variable.

关键词： Cerebral Ischemia Cardiac Arrest Cardiopulmonary Resuscitation Hypothermia Neuroprotection Telemetry Hyperthermia

非损伤性功能成像技术:正电子发射断层扫描术、磁共振波谱分析和动态对比增强磁共振影像学(英文)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国临床药理学与治疗学 2007年第11期12卷 1295-1298页

作者： ruediger E.Port Genentech Inc. South San FranciscoCA94080USA

当前在医药工业中越来越关注将非损伤性功能成像技术作为潜在的病人体内药物作用早期检测技术。正电子发射断层扫描术可监测组织中放射标记的药物和其代谢物的绝对浓度,或者是特殊受体的配体浓度,且可以三维直观地显示它们在体内的分布... 详细信息

当前在医药工业中越来越关注将非损伤性功能成像技术作为潜在的病人体内药物作用早期检测技术。正电子发射断层扫描术可监测组织中放射标记的药物和其代谢物的绝对浓度,或者是特殊受体的配体浓度,且可以三维直观地显示它们在体内的分布。磁共振波谱分析可监测体内未标记药物的代谢转化。动态对比增强磁共振影像学可显示小分子、亲水的造影剂在血浆与组织细胞间隙间的即时分布,并可以用来检测抗血管或血管生成的化合物的作用。

关键词：正电子发射断层扫描术磁共振波谱分析功能成像技术磁共振影像学动态对比增强非损伤性检测技术药物作用

Attachment in Children with ADHD

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Behavioral and Brain Science 2017年第11期7卷 497-510页

作者： Sebastian Franke ruediger Kissgen Maya Krischer Kathrin Sevecke Faculty II Developmental Science and Special Education University of Siegen Siegen Germany Clinic of Child and Adolescent Psychiatry and Psychotherapy University of Cologne Cologne Germany Department of Child and Adolescent Psychiatry Medical University of Innsbruck Innsbruck Austria

Objective: Parallels in findings of attachment and ADHD research suggest a connection between both constructs. However, the few articles dealing with that tie investigate children with all conceivable expressions of ADHD and have not found sufficient evidence regarding the connection between ADHD and attachment. This study sought to collect evidence of a possible connection between the two aspects among children with the predominantly inattentive ADHD type. Method: The sample consisted of 93 children aged 5 - 9 years, 48 of whom had an ADHD diagnosis of the predominantly inattentive type. Attachment was coded using the German adaptation of the Attachment Story Completion Task, externalizing behavior problems were rated using the Child Behavior Checklist 4 - 18. ADHD was assessed using both clinical diagnoses as well as the German ADHD Rating scale. Results: Results revealed a large difference in the distribution of attachment classification between children with ADHD and those without ADHD. Regression analysis, however, showed no independent effect on ADHD when externalizing behavior problems were controlled for. Conclusions: Both constructs seem to be connected, however, in the investigation of the influence of attachment on the disorder, ADHD as a global construct is too unspecific. As opposed to previous studies, considering only the inattentive type, the relation might completely be moderated by externalizing behavior problems. Subsequent studies should first focus on specific symptom patterns which at best should be analyzed within longitudinal studies.

关键词： Attachment ADHD Externalizing Behavior Problems School Children

Isolated subcutaneous implantation of a borderline ovarian tumor:A case report and review of the literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Oncology 2016年第2期7卷 270-274页

作者： Malgorzata Banys-Paluchowski Borsu Yeganeh Jutta Luettges Achim Maibach ruediger Langenberg Natalia Krawczyk Peter Paluchowski Holger Maul Gerhard Gebauer Department of Obstetrics and Gynecology Marienkrankenhaus Hamburg Department of Pathology Marienkrankenhaus Hamburg Department of Obstetrics and Gynecology University Hospital Duesseldorf Department of Obstetrics and Gynecology Regio Klinik Pinneberg

Laparoscopy-related tumor implantations of gynecological malignancies into the subcutaneous tissue are rarely *** report an interesting case of a 46-year-old female who presented with an abdominal subcutaneous metastasis of a borderline ovarian *** patient received a laparoscopic unilateral adnexectomy for a solid-cystic tumor of the right *** workup showed a papillary borderline tumor of mucinous *** days later she underwent a hysterectomy,left adnexectomy,appendectomy and *** of the peritoneum revealed no intraperitoneal *** exploration showed a non-invasive implant of a borderline tumor in the subcutaneous tissue above the fascia that had no contact to the *** is hypothesized that tumor cells may have been implanted during a previous laparoscopy,the most recent of which had been fourteen years prior to her current *** risk factors for port-site malignancies have been *** manipulation and extraction of tumor tissue without a protective bag may contribute to development of trocarsite metastasis.

关键词： Laparoscopy Subcutaneous metastasis Tumor implantation Borderline tumor of the ovary

Comparison of Link-by-Link Admission Control and Capacity Overprovisioning

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparison of Link-by-Link Admission Control and Capacity Ov...

The 19th International Teletraffic Congress-ITC19

作者： ruediger Martin Michael Menth Joachim Charzinski Dept. of Distributed Systems Inst. of Computer ScienceUniversity of Würzburg Am HublandD-97074 WürzburgGermany Dept. of Distributed Systems Inst. of Computer ScienceUniversity of Würzburg Am HublandD-97074 WürzburgGermany Siemens AG MunichGermany

＜正＞There are two basic approaches to achieve Quality of Service （QoS） for communication networks: admission control （AC） and capacity overprovisioning （CO） AC requires less capacity than CO because it can block excess traffic, preventing it from disturbing the QoS of admitted flows. CO on the other hand is simple and cheaper to implement than AC, which makes it an attractive option for Internet service providers that do not have an AC infrastructure yet, at the risk of the network being overwhelmed by excess traffic in rare cases. In this paper we contribute further insights to this discussion by quantifying the ratio of required capacity for CO:AC in certain networking scenarios including rare overload and hot spot scenarios

关键词： QoS admission control capacity overprovisioning

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

基于变密度法的压铸机模板拓扑优化设计

特种铸造及有色合金 2023年第3期43卷 428-432页

作者：李世豪伞红军吴智恒张华伟 ruediger Heim 昆明理工大学机电工程学院广东省科学院智能制造研究所 Fraunhofer Institute of Structural Durability and System Reliability LBF

针对当前压铸机合模机构中模板质量大、成本高的问题,结合工程实际应用情况,采用基于变密度法的结构拓扑优化和尺寸优化联合设计方案,应用Optisruct软件分别对定模板、尾板和动模板进行了优化,建立了相应的拓扑优化设计模型,定义了优化... 详细信息

针对当前压铸机合模机构中模板质量大、成本高的问题,结合工程实际应用情况,采用基于变密度法的结构拓扑优化和尺寸优化联合设计方案,应用Optisruct软件分别对定模板、尾板和动模板进行了优化,建立了相应的拓扑优化设计模型,定义了优化目标函数和约束函数,研究了约束体积分数和惩罚因子对拓扑优化结果的影响。通过与优化前的模板结构进行比较,3大模板的总质量由74.68 t减少为66.35 t,减重率达11.5%,且应力分布更加均匀。

关键词：压铸机模板拓扑优化轻量化变密度法