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Mass transfer and loss of the massive semi-detached binary AI Crucis

Research in Astronomy and Astrophysics 2010年第5期10卷 438-444页

作者： er-Gang Zhao Sheng-Bang Qian E. Femanindez Lajus Carolina von Essen Li-Ying Zhu National Astronomical Observatories / Yunnan Observatory Chinese Academy of SciencesKunming 650011 China Key Laboratory for the Structure and Evolution of Celestial Objects Chinese Academy ofSciences Kunming 650011 China Graduate University of Chinese Academy of Sciences Beijing 100049 China Facultad de Ciencias Astron6micas y Geoffsicas Universidad Nacional de La Plata 1900 LaPlata Buenos Aires Argentina

AI Crucis is a short-period semi-detached massive close binary （P = 1.41771d, Sp.=B1.5） in the open cluster NGC 4103. It is a good astrophysical laboratory for investigating the formation and evolution of massive close binary stars via case A mass transfer. Orbital period variations of the system were analyzed based on one newly determined eclipse time and the others compiled from the literature. It is discovered that the orbital period of the binary is continuously increasing at a rate of dP/dt = ＋1.00（±0.04） × 10-7 d yr-1. After the long-term increase is subtracted from the O - C diagram, weak evidence indicates the presence of a cyclic oscillation with a period of 30.1yr, which may reveal a very cool stellar companion in the system. The long-term period increase can be explained by mass transfer from the less massive component to the more massive one. This is in agreement with the semidetached configuration of the binary, indicating that the system is undergoing a slow mass-transfer stage on the nuclear time scale of the secondary. However, it is found that the slow mass transfer is insufficient to cause the observed period increase, which suggests that the stellar wind from the hot component should contribute to the amount of period increase dP/dt = ＋0.54× 10-7 d yr-1 that corresponds to a mass loss rate of M˙1 = 2.72 × 10-7 M yr-1. It is estimated that the hot component lost a total mass of 4.1M during the slow mass-transfer stage and, thus, the evolution of the binary system should be changed greatly by the mass loss.

关键词： stars: binaries: close — stars: binaries: eclipsing — stars: individual (AI Crucis) — stars: early-type — stars: evolution

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Diatom-inspired Plastic Deformation Elements for Energy Absorption in Automobiles

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Journal of Bionic Engineering 2015年第4期12卷 613-623页

作者： Christin Hundertmark rudiger Tinter Marc Ortelt Marcus J B Hauser Otto-von-Guericke University Magdeburg Institute of Experimental Physics Biophysics Group Universitatsplatz 2 39106 Magdeburg Germany Volkswagen AG Plastic Business Sector Postbox O11/1219 38436 Wolfsburg Germany

We report on a biomimetic approach for the construction of a deformation element in vehicles which absorbs energy in the case of lateral collisions. We aim at simultaneously maximising the energy absorption capacity of the component and mini- mising its weight. The examined deformation element, a crash-pad is inspired by the structure of a diatom which is known for its structural stability. As the natural counterpart, our crash pad is characterized by an undulated shape. The three undulations of the crash pad are of different height and provide for a sequential absorption of the impact energy. Compression tests were performed on the prototypes of the crash pad that were produced from different materials, namely a conventional talc reinforced poly- propylene and a natural fibre reinforced plastic. Compression tests revealed that the bioinspired crash pads performed better or equal than their technical counterpart. As required, the bioinspired components deformed continuously with the increase in deformation force. Since the differences in the properties of the used materials were small, the increased energy absorption properties were predominantly due to the structure of the biomimetic deformation element.

关键词： biomimetic approach deformation element side crash natural fibre reinforced plastic energy absorption diatoms

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Requirement of a Homolog of Glucosidase Ⅱ β-Subunit for EFR-Mediated Defense Signaling in Arabidopsis thaliana

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Molecular Plant 2010年第4期3卷 740-750页

作者： Nina von Numers Mantas Survila Markku Aalto Martine Batoux Pekka Heino E. Tapio Palva Jing Li Division of Genetics Department of Biosciences Viikki Biocenter University of Helsinki POB 56 FIN-00014 Helsinki Finland The Sainsbury laboratory Norwich Research Park Norwich NR4 7UH United Kingdom

EFR is a plasma-membrane resident receptor responsible for recognition of microbial elongation factorTu （EF-Tu） and thus triggering plant innate immunity to fend off phytopathogens. Functional EFR must be subject to the endoplasmic reticulum quality control （erQC） machinery for the correct folding and proper assembly in order to reach its final destination. Genetic studies have demonstrated that erD2b, a counterpart of the yeast or mammalian HDEL receptor erD2 for retaining proteins in the endoplasmic reticulum （er） lumen, is required for EFR function in plants （Li et al., 2009）. In this study, we characterized the Arabidopsis glucosidase Ⅱ β--subunit via the H DEL motif against the non-redundant protein database. Data mining also revealed that the glucosidase Ⅱ β--subunit gene has a highly similar expression pattern to erD2b and the other known erQC components involved in EFR biogenesis. Importantly, the T-DNA insertion lines of the glucosidase Ⅱ β-subunit gene showed that EFR-controlled responses were substantially reduced or completely blocked in these mutants. The responses include seedling growth inhibition, induction of marker genes, MAP kinase activation, and callose deposition, trigged by peptide elf18, a full mimic of E F-Tu. Taken together, ourdata indicate a requirement of the glucosidase Ⅱ β-subunitfor EFR function.

关键词： Arabidopsis thaliana glucosidase Ⅱ β-subunit endoplasmic reticulum quality control EFR innate immunity.

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*** von Hermann Hesse Der Poet der wilden Jugend

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德语学习 2012年第5期 13-16页

作者： Anika von Greve-Dierfeld

Vor 50 Jahren starb Hermann *** Autor war scheu,sogar selbstzerstrerisch - und bedient auch heute noch mit Werken wie dem"Steppenwolf"oder"Siddhartha"die Sehnsucht junger Menschen. er war weich und gleichzeitig von ... 详细信息

关键词：德语学习阅读知识课外阅读学习方法

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High-performance synaptic transistors for neuromorphic computing

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Chinese Physics B 2020年第4期29卷 1-14页

作者： Hai Zhong Qin-Chao Sun Guo Li Jian-Yu Du He-Yi Huang er-Jia Guo Meng He Can Wang Guo-Zhen Yang Chen Ge Kui-Juan Jin Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of ScienceBeijing 100049China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China Songshan Lake Materials Laboratory Dongguan 523808China

The further development of traditional von Neumann-architecture computers is limited by the breaking of Moore’s law and the von Neumann bottleneck, which make them unsuitable for future high-performance artificial intelligence (AI)systems. Therefore, new computing paradigms are desperately needed. Inspired by the human brain, neuromorphic computing is proposed to realize AI while reducing power consumption. As one of the basic hardware units for neuromorphic computing, artificial synapses have recently aroused worldwide research interests. Among various electronic devices that mimic biological synapses, synaptic transistors show promising properties, such as the ability to perform signal transmission and learning simultaneously, allowing dynamic spatiotemporal information processing applications. In this article, we provide a review of recent advances in electrolyte-and ferroelectric-gated synaptic transistors. Their structures, materials,working mechanisms, advantages, and disadvantages will be presented. In addition, the challenges of developing advanced synaptic transistors are discussed.

关键词： synaptic transistor artificial synapse synaptic plasticity electrolyte gating ferroelectric gating

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PSR波纹板片的热强度分析

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热能动力工程 2005年第4期20卷 342-345页

作者：刘振宇程惠尔上海交通大学机械与动力工程学院上海200030

提出一种新型紧凑式回热器———一次表面回热器(PSR)的强度设计技术。结合船用ICR燃气轮机一次表面回热器研发,以3.7MW燃气轮机为背景,根据热弹性力学和传热学理论,建立PSR板片热强度分析物理数学模型,并对波纹曲线为椭圆、正弦波和抛... 详细信息

提出一种新型紧凑式回热器———一次表面回热器(PSR)的强度设计技术。结合船用ICR燃气轮机一次表面回热器研发,以3.7MW燃气轮机为背景,根据热弹性力学和传热学理论,建立PSR板片热强度分析物理数学模型,并对波纹曲线为椭圆、正弦波和抛物线的3种常见波纹传热板片所受热应力做了对比计算,分析了板片厚度,两侧压差,本身温度及形状对板片热强度的影响。给出基于vonMise等效应力极值σvmax的板片最小设计厚度δmin,还研究了波纹板片在典型工况下的弹性变形情况。本文工作对PSR的结构设计有重要参考价值。

关键词：燃气轮机一次表面回热器波纹板片热应力

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20世纪火箭工程的奠基人——沃纳·冯·布劳恩

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自然辩证法通讯 2005年第6期27卷 91-98页

作者：刘二中中国科学院研究生院人文学院北京100049

沃纳.冯.布劳恩(Wernher von Braun,1912-1977)是20世纪液体燃料火箭技术和宇航工程的开创者和奠基人。二战期间他在德国主持开发成功著名的V-2导弹。战后他在美国主持研制成功“红石”(Redstone)火箭、“丘辟特”(Jupiter)导弹,并发射... 详细信息

沃纳.冯.布劳恩(Wernher von Braun,1912-1977)是20世纪液体燃料火箭技术和宇航工程的开创者和奠基人。二战期间他在德国主持开发成功著名的V-2导弹。战后他在美国主持研制成功“红石”(Redstone)火箭、“丘辟特”(Jupiter)导弹,并发射成功美国第一颗人造地球卫星。他领导完成“土星”巨型火箭,为“阿波罗”计划的成功奠定了基础。本文介绍了他的生平、主要科学技术贡献以及独特的工作方法和技术观。

关键词：沃纳·冯·布劳恩火箭导弹宇航

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KL-6与体外循环中行持续低潮气量通气的成年瓣膜患者围术期肺氧合功能改变的相关性研究

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四川大学学报（医学版） 2019年第3期50卷 350-356页

作者：沈嘉渝张尔永胡佳四川大学华西医院心脏大血管外科成都610041

目的初步探讨体外循环(CPB)术中持续低潮气量通气对成年瓣膜患者体内涎液化糖链抗原-6(KL-6)的表达水平及患者围术期肺氧合功能变化的影响,评估KL-6与此类患者围术期氧合功能改变的相关性。方法连续纳入2017年9月至2018年1月在我科接受... 详细信息

目的初步探讨体外循环(CPB)术中持续低潮气量通气对成年瓣膜患者体内涎液化糖链抗原-6(KL-6)的表达水平及患者围术期肺氧合功能变化的影响,评估KL-6与此类患者围术期氧合功能改变的相关性。方法连续纳入2017年9月至2018年1月在我科接受心脏瓣膜手术的成年患者60例,随机分为对照组(n=30例,CPB期间未接受机械通气)和试验组(n=30例,CPB期间接受持续低潮气量通气)。动态监测患者围术期血清学指标及肺氧合功能变化情况,比较两组患者围术期临床结局,并分析KL-6表达水平与患者围术期肺氧合功能改变的相关性。结果对照组及试验组患者CPB术后血清及肺泡灌洗液中KL-6水平差异均有统计学意义(P0.05)。结论术中持续低潮气量通气可有效抑制患者体内KL-6的表达,但对围术期临床结局无明显影响。KL-6表达水平可有效反映围术期肺氧合功能的改变。

关键词：体外循环涎液化糖链抗原-6 机械通气肺功能

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An Electromagnetic Perspective of Artificial Intelligence Neuromorphic Chips

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Electromagnetic Science 2023年第3期1卷 50-67页

作者： er-Ping Li Hanzhi Ma Manareldeen Ahmed Tuomin Tao Zheming Gu Mufeng Chen Quankun Chen Da Li Wenchao Chen ZJU-UIUC Institute College of Information Science and Electronic EngineeringZhejiang UniversityHangzhou 310000China

The emergence of artificial intelligence has represented great potential in solving a wide range of complex ***,traditional general-purpose chips based on von Neumann architectures face the“memory wall”problem when applied in artificial intelligence *** on the efficiency of the human brain,many intelligent neuromorphic chips have been proposed to emulate its working mechanism and neuron-synapse *** the emergence of spiking-based neuromorphic chips,the computation and energy efficiency of such devices could be enhanced by integrating a variety of features inspired by the biological *** with the rapid development of neuromorphic chips,it is of great importance to quickly initiate the investigation of the electromagnetic interference and signal integrity issues related to neuromorphic chips for both CMOS-based and memristor-based artificial intelligence integrated ***,this paper provides a review of neuromorphic circuit design and algorithms in terms of electromagnetic issues and opportunities with a focus on signal integrity issues,modeling,and ***,the heterogeneous structures of neuromorphic circuits and other circuits,such as memory arrays and sensors using different integration technologies,are also reviewed,and locations where signal integrity might be compromised are ***,we provide future trends in electromagnetic interference and signal integrity and outline prospects for upcoming neuromorphic devices.

关键词： Signal integrity Electromagnetic interference Electromagnetic design Neuromorphic chips Heterogeneous integration

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A variant in IL6ST with a selective IL-11 signaling defect in human and mouse

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Bone Research 2020年第2期8卷 157-168页

作者： Tobias Schwerd Freia Krause Stephen R.F.Twigg Dominik Aschenbrenner Yin-Huai Chen Uwe Borgmeyer Miryam Müller Santiago Manrique Neele Schumacher Steven A.Wall Jonathan Jung Timo Damm Claus-Christian Glüer Jürgen Scheller Stefan Rose-John E.Yvonne Jones Arian Laurence Andrew O.M.Wilkie Dirk Schmidt-Arras Holm H.Uhlig Translational Gastroenterology Unit John Radcliffe HospitalUniversity of OxfordOxfordUK Department of Pediatrics Dr von Hauner Children’s HospitalLMU MunichMunichGermany Christian-Albrechts-University Kiel Institute of BiochemistryKielGermany Clinical Genetics Group MRC Weatherall Institute of Molecular MedicineUniversity of OxfordJohn Radcliffe HospitalOxfordUK Center for Molecular Neurobiology Hamburg(ZMNH) University Medical Center Hamburg-EppendorfHamburgGermany Division of Structural Biology Wellcome Trust Centre for Human GeneticsUniversity of OxfordOxfordUK Craniofacial Unit Department of Plastic and Reconstructive SurgeryOxford University Hospitals NHS Foundation TrustJohn Radcliffe HospitalOxfordUK Section Biomedical Imaging Department of Radiology and NeuroradiologyUniversity Medical Center Schleswig-HolsteinKielGermany Institute of Biochemistry and Molecular Biology Ⅱ Medical FacultyHeinrich-Heine-UniversityDüsseldorfGermany Department of Paediatrics University of OxfordOxfordUK NIHR Oxford Biomedical Research Centre OxfordUK The Beatson Institute for Cancer Research GlasgowUK School of Medicine University of GlasgowGlasgowUK

The GP130 cytokine receptor subunit encoded by IL6ST is the shared receptor for ten cytokines of the IL-6 family. We describe a homozygous non-synonymous variant in IL6 ST(p.R281 Q) in a patient with craniosynostosis and retained deciduous teeth. We characterize the impact of the variant on cytokine signaling in vitro using transfected cell lines as well as primary patient-derived cells and support these findings using a mouse model with the corresponding genome-edited variant Il6 st p.R279 Q. We show that human GP130 p.R281 Q is associated with selective loss of IL-11 signaling without affecting IL-6, IL-27, OSM, LIF, CT1, CLC, and CNTF signaling. In mice Il6 st p.R279 Q lowers litter size and causes facial synostosis and teeth abnormalities. The effect on IL-11 signaling caused by the GP130 variant shows incomplete penetrance but phenocopies aspects of IL11 RA deficiency in humans and mice. Our data show that a genetic variant in a pleiotropic cytokine receptor can have remarkably selective defects.

关键词： IL11 cytokine facial

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