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Clinical profile and outcomes of ocular surface squamous neoplasia at the Philippine General Hospital:a retrospective study

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International Journal of Ophthalmology(English edition) 2025年第1期18卷 132-138页

作者： Mary Ellaine S.Diaz ruben lim bon siong Justin Alan Yao Gary John V.Mercado Department of Ophthalmology and Visual Sciences University of the Philippines Manila-Philippine General HospitalManila 1000Philippines Eye Institute St.Luke’s Medical CenterQuezon CityManila 1112Philippines Eye and Vision Institute The Medical CityPasig 1800Philippines

AIM:To evaluate the demographics,clinical characteristics,treatments,and outcomes of patients with ocular surface squamous neoplasia(OSSN)at the Philippine General ***:This was a single-center,11-year retrospective,cross sectional case series on 18 cases of OSSN seen between January 2012 to June *** patient’s demographics,presenting symptoms,tumor characteristics,histopathologic diagnosis,treatment,outcomes,and duration of follow-up were ***:Out of 33 identified cases of OSSN,only 18 were eligible for inclusion in the *** age was 60.78y(range 31 to 80),with male predominance(66.67%).The left eye was most commonly affected(61.11%)with most presenting with fleshy mass(83.33%).Most tumors were located nasally(66.67%)and were predominantly papilliform(44.44%)in morphology with associated hyperpigmentation(38.89%).Squamous cell carcinoma(SCCA)was the most common histopathologic diagnosis(72.22%).The main primary treatment was surgical excision(94.44%)with or without adjunctive therapy,with only 1 patient undergoing first-line topical *** 3 recurrences(16.67%)were noted with a median followup of 7.5mo.A statistically significant recurrence-free odds leaning towards the utilization of cryotherapy was ***:OSSN seen at the Philippine General Hospital is presented as a limbal papilliform mass,most commonly affecting elderly *** excision with adjuvant cryotherapy and/or chemotherapy is the preferred mode of treatment.

关键词： ocular surface squamous neoplasia conjunctival malignancy squamous cell carcinoma conjunctival intraepithelial neoplasia

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翼状胬肉切除术后应用纤维蛋白胶或缝线固定自体结膜植片的比较

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世界核心医学期刊文摘（眼科学分册） 2005年第11期1卷 53-53页

作者： Uy H.S. Reyes J.M.G. Flores J.D.G. lim-bon-siong R. 杨建刚 Asian Eye Institute 9F Phinma Plaza Building Rockwell CenterMakati 1200 Philippines Dr.

Purpose: To compare the efficacy and safety of fibrin glue and suturing for at taching conjunctival autografts among patients undergoing pterygium excision. De sign: Prospective, randomized, interventional case series. Participants: Twenty -two patients undergoing excision of primary pterygium. Methods: A superior con junctival autograftwas harvested and transferred onto bare sclera after pterygiu mexcision. Fibrin glue (Beriplast P) was used to attach the autograft in 11 eyes and nylon 10-0 suture was used to attach the autograft in 11 eyes. The patient s were followed up for 2 months. Main Outcome Measures: Graft success, recurrenc e rate, operating time, patient comfort. Results: All conjunctival autografts in both groups were successfully attached and were intact after 2 months. The aver age operating time for the fibrin glue groupwas significantly shorter (P<0.001). Postoperative symptoms were fewer for the fibrin glue group than the suture gro up. One patient (9%) from the fibrin group experienced subconjunctival hemorrha ge, and 1 patient (9%) from the suture group experienced partial graft dehiscen ce. Conclusions: Fibrin glue is a safe and effective method for attaching conjun ctival autografts. The use of fibrin glue results in shorter operating times and less postoperative discomfort.

关键词：翼状胬肉切除术纤维蛋白胶植片原发性翼状胬肉复发率干预性术后症状手术区线组手术时间

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