检索结果-南通市图书馆

Generation and α-hydroxyalkylation of a novel 3-piperidinol N-α-carbanion intermediate

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2009年第10期52卷 1631-1638页

作者： ZHENG Xiao CHEN Guo ruan YuanPing huang PeiQiang Department of Chemistry and Key Laboratory for Chemical Biology of Fujian Province College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China

The (S)-sulfide 6 has been synthesized as a synthetic equivalent of novel 3-piperidinol N-α-carbanion B via deprotonation and lithium naphthanelide (LN)-mediated reductive lithiation. The reaction of the 3-piperidinol N-α-carbanion intermediate B with carbonyl compounds gave, besides some reduced product 2a, the desired α-hydroxyalkylation products 12-17 with excellent 2,3-diastereoselectivity. The reductive α-hydroxyalkylation with unsymmetric carbonyl compounds led to only 50:50 to 77:23 diastereoselectivities at the C-1' carbinol center.

关键词： sulfide N-α-carbanion lithium-naphthanelide reductive lithiation carbonyl compounds α-hydroxyalkylation diastereoselectivity

A Fully Pipelined Probability Density Function Engine for Gaussian Copula Model

在线全文

学校读者我要写书评

暂无评论

Tsinghua Science and Technology 2014年第2期19卷 195-202页

作者： Huabin ruan Xiaomeng huang Haohuan Fu Guangwen Yang Department of Computer Science and Technology Tsinghua University Center for Earth System Science Tsinghua University

The Gaussian Copula Probability Density Function （PDF） plays an important role in the fields of finance, hydrological modeling, biomedical study, and texture retrieval. However, the existing schemes for evaluating the Gaussian Copula PDF are all computationally-demanding and generally the most time-consuming part in the corresponding applications. In this paper, we propose an FPGA-based design to accelerate the computation of the Gaussian Copula PDF. Specifically, the evaluation of the Gaussian Copula PDF is mapped into a fully-pipelined FPGA dataflow engine by using three optimization steps： transforming the calculation pattern, eliminating constant computations from hardware logic, and extending calculations to multiple pipelines. In the experiments on 10 typical large-scale data sets, our FPGA-based solution shows a maximum of 1870 times speedup over a well-tuned single- core CPU-based solution, and 610 times speedup over a well-optimized parallel quad-core CPU-based solution when processing two-dimensional data.

关键词： Gaussian Copula probability density function FPGA pipeline optimization

Novel Even Beam Splitters Based on Subwavelength Binary Simple Periodic Rectangular Structure

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2015年第2期7卷 177-182页

作者： Haixuan huang Shuangchen ruan Tuo Yang Ping Xu College of Electronic Science and Technology Institute of Micro-Nano Optoelectronic Technology Shenzhen University

In this paper, a novel method of a subwavelength binary simple periodic rectangular structure is presented to realize even beam splitting by combining the rigorous couple-wave analysis with the genetic algorithm. Several even splitters in the terahertz region were designed and one of the silicon-based beam splitters designed to separate one incident beam into four emergent beams has total efficiency up to 92.23 %. Zero-order diffraction efficiency was reduced to less than 0.192 % and the error of uniformity decreased to 6.51 9 10-6. These results break the limitation of even beam splitting based on the traditional scalar theory. In addition, the effects of the incident angle, wavelength, as well as the polarizing angle on the diffraction efficiency and uniformity were also investigated.

关键词： Beam splitters Binary optics Diffraction gratings Diffraction theory Subwavelength structures

Performance and microbial response during the fast reactivation of Anammox system by hydrodynamic stress control

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2014年第9期26卷 1861-1868页

作者： Yuan Li Zhenxing huang Wenquan ruan Hongyan Ren Hengfeng Miao School of Environment and Civil Engineering Jiangnan University

Anaerobic ammonium oxidation （Anammox） has become a promising method for biological nitrogen removal. However, this biotechnology application is always limited due to the low growth rate and biomass yield of Anammox bacteria. This study investigated the process of fast reactivation of an Anammox consortium idled for 2 years uia hydrodynamic stress control. The results showed that the Anammox system was efficiently and quickly reactivated by shortening of the hydraulic retention time （I-IRT） of the reactor from 12 to 6 hr within 68 days of operation. Moreover, at a 4-hr HRT with an influent total nitrogen loading rate of 1.2 kg N/（***）, the reactor maintained high biological performance with an ammonium removal loading rate of 0.52 kg N/（***） and a nitrite removal rate of 0.59 kg N/（***）. In the reactivated Anammox reaction, the stoichiometric coefficients of NH4-N to NOE-N and NH4-N to NO4-N were 1：1.04± 0.08 and 1：0.31 ± 0.03, respectively. The specific Anammox activity and hydrazine oxidoreductase activity, both of which represent the degree of Anammox bacteria present, increased as the hydrodynamic stress increased and were maximally （125.38 ± 3.01 mg N/（g ***） and 339.42 ± 6.83 μmol/（min.g VSS）, respectively） at 4-hr HRT. Microbial response analysis showed that the dominant microbial community was obviously shifted and the dominance of Anammox bacteria was enhanced durinR the hydrodynamic selection.

关键词： Anaerobic ammonium oxidationHydrodynamic stressFast reactivationHydrazine oxidoreductase

Measurement of the thermal transport properties of dielectric thin films using the micro-Raman method

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第1期10卷 7-16页

作者： Shuo huang Xiao-dong ruan Xin FU Hua-yong YANG State Key Laboratory of Fluid Power Transmission and Control Zhejiang University Hangzhou 31002 7 China

The micro-Raman method is a non-contact and non-destructive method for thermal conductivity *** reduce the measurement error induced by the poor fit of the basic equation of the original micro-Raman method,we developed a new basic equation for the heat source of a Gaussian laser *** on the new basic equation,an analytical heat transfer model has been built to extend the original micro-Raman method to thin films with submicrometer-or nanometer-scale ***-periments were performed to measure the thermal conductivity of dielectric thin films with submicrometer-or nanometer-scale *** thermal resistance of the interface between dielectric thin films and their silicon substrate was also *** obtained thermal conductivity of silicon dioxide film is 1.23W/(m.K),and the interface thermal resistance between silicon dioxide film and substrate is 2.35×10-8m2.K/*** thermal conductivity and interface thermal resistance of silicon nitride film are 1.07W/(m.K)and 3.69×10-8m2.K/W,*** experimental results are consistent with reported data.

关键词： Thermal conductivity Dielectric thin films Submicrometer- or nanometer-scale Porous silicon Thermal effect micro-systems (TEMS)

Black phosphorus quantum dots induce myocardial inflammatory responses and metabolic disorders in mice

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第3期137卷 53-64页

作者： Chao Shen Xiaoyan Ding Jinpeng ruan Fengkai ruan Weiping Hu Jiyi huang Chengyong He Yi Yu Zhenghong Zuo Department of Nephrology State Key Laboratory of Cellular Stress BiologySchool of Life SciencesFaculty of Medicine and Life SciencesFujian Clinical Research Center for Chronic Glomerular DiseaseThe First Affiliated Hospital of Xiamen UniversitySchool of MedicineXiamen UniversityXiamen 361102China

As an ultrasmall derivative of black phosphorus(BP)sheets,BP quantum dots(BP-QDs)have been effectively used in many ***,information on the cardiotoxicity induced by BP-QDs remains *** aimed to evaluate BP-QD-induced cardiac toxicity in *** examination of heart tissue sections was *** sequencing,real-time quantitative PCR(RT–qPCR),western blotting,and enzyme-linked immunosorbent assay(ELISA)assays were used to detect the m RNA and/or protein expression of proinfammatory cytokines,nuclear factor kappa B(NF-κB),phosphatidylinositol3 kinase-protein kinase B(PI3K-AKT),peroxisome proliferator-activated receptor gamma(PPARγ),and glucose/lipid metabolism pathway-related *** found that heart weight and heart/body weight index(HBI)were significantly reduced in mice after intragastric administration of 0.1 or 1 mg/kg BP-QDs for 28 *** addition,obvious infammatory cell infiltration and increased cardiomyocyte diameter were observed in the BP-QD-treated *** expression of proinfammatory cytokines and genes related to the NF-κB signaling pathway further confirmed that BP-QD exposure induced infammatory *** addition,BP-QD treatment also affected the PI3K-AKT,PPARγ,thermogenesis,oxidative phosphorylation,and cardiac muscle contraction signaling *** expression of genes related to glucose/lipid metabolism signaling pathways was dramatically affected by BP-QD exposure,and the effect was primarily mediated by the PPAR signaling *** study provides new insights into the toxicity of BP-QDs to human health.

关键词： BP-QDs Cardiac toxicity Infammatory responses NF-κB signaling pathway PPARγsignaling pathway Glucose/lipid metabolism

Dr. Chi-Ming Chu： Respected founder of molecular virology and pioneer of biologicals in China

在线全文

学校读者我要写书评

暂无评论

Protein & Cell 2017年第9期8卷 629-633页

作者： Weizheng Yan Baoying huang Li ruan Wenjie Tan Biotech Center for Viral Diseases Emergency Key Laboratory of Medical Virology Ministry of Health National Institute for ViralDisease Control and Prevention China CDC Beijing 102206 China

＂I have the greatest respect for Dr. Chu, who upheld great standards of science during very difficult times in China. His contributions to the genetic characterisation of influenza viruses were extraordinary.＂

关键词：

Frequency Shifts of Luminescence for ZnO Nanoparticles in Porous Alumina Template

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2006年第z1期24卷 257-260页

作者： ruan Yongfeng Jing Hongqi huang Boxian Lu Shuhua Zhan Shouchao School of Science Tianjin University Tianjin 300072 China School of Science Tianjin University Tianjin 300072 China School of Science Tianjin Industry University Tianjin 300160 China School of Science Tianjin University Tianjin 300072 China School of Science Tianjin University Tianjin 300072 China

ZnO nanoparticles in porous anodized alumina were fabricated by sol-gel method. The PL spectra of pure ZnO nanoparticles, porous alumina template and the ZnO/PAA composite system were investigated after annealed at different temperatures. The annealing of ZnO/PAA composite system displays very complicated behavior, where changing of luminescence intensity and a "red shift" of emission frequency were observed at less or higher than 500 ℃ of the annealing temperature, respectively. To explain the phenomenon, it is considered that the emission origin of the green luminescence of ZnO nanoparticles came from OZn. It is suggested that the ZnO/PAA composite system should be annealed at the temperature above 500 ℃ in order to get intense luminescence of ZnO nanoparticle.

关键词： ZnO sol-gel porous alumina templates ZnO/PAA composite system

Assessment of International GNSS Service Global Ionosphere Map products over China region based on measurements from the Crustal Movement Observation Network of China

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Earth and Planetary Physics 2024年第2期8卷 400-407页

作者： Jin Hu HaiBing ruan FuQing huang ShengYang Gu XianKang Dou Institute of Space Weather Nanjing University of Information Science and TechnologyNanjing 210044China State Key Laboratory of Space Weather Chinese Academy of Sciences(CAS)Beijing 100190China School of Electronic Information Wuhan UniversityWuhan 430072China Wuxi Research Institute Nanjing University of Information Science and TechnologyWuxi Jiangsu 214000China CAS Key Laboratory of Geospace Environment School of Earth and Space SciencesUniversity of Science and Technology of ChinaHefei 230026China

The global ionosphere maps(GIM)provided by the International GNSS Service(IGS)are extensively utilized for ionospheric morphology monitoring,scientific research,and practical *** the credibility of GIM products in data-sparse regions is of paramount *** this study,measurements from the Crustal Movement Observation Network of China(CMONOC)are leveraged to evaluate the suitability of IGS-GIM products over China region in *** indices of mean error(ME),root mean square error(RMSE),and normalized RMSE(NRMSE)are then utilized to quantify the accuracy of IGS-GIM *** revealed distinct local time and latitudinal dependencies in IGS-GIM errors,with substantially high errors at nighttime(NRMSE:39%)and above 40°latitude(NRMSE:49%).Seasonal differences also emerged,with larger equinoctial deviations(NRMSE:33.5%)compared with summer(20%).A preliminary analysis implied that the irregular assimilation of sparse IGS observations,compounded by China’s distinct geomagnetic topology,may manifest as error *** results suggest that modeling based solely on IGS-GIM observations engenders inadequate representations across China and that a thorough examination would proffer the necessary foundation for advancing regional total electron content(TEC)constructions.

关键词： International GNSS Service(IGS)Global Ionosphere Maps(GIM) Crustal Movement Observation Network of China(CMONOC) total electron content(TEC) data assessment