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A Comparative Study on Polynomial Expansion Method and Polynomial Method of Particular Solutions

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Advances in Applied Mathematics and Mechanics 2022年第3期14卷 577-595页

作者： Jen-Yi Chang ru-yun chen Chia-cheng Tsai Tainan University of Technology Tainan 71002Taiwan China Department of Harbor and River Engineering Taiwan Ocean UniversityKeelung 202301Taiwan China Bachelor Degree Program in Ocean Engineering and Technology Taiwan Ocean UniversityKeelung 202301Taiwan China Center of Excellence for Ocean Engineering Taiwan Ocean UniversityKeelung 202301Taiwan China

In this study,the polynomial expansion method(PEM)and the polynomial method of particular solutions(PMPS)are applied to solve a class of linear elliptic partial differential equations(PDEs)in two dimensions with constant coefﬁ*** the solution procedure,the sought solution is approximated by the Pascal polynomials and their particular solutions for the PEM and PMPS,*** multiple-scale technique is applied to improve the conditioning of the resulted linear equations and the accuracy of numerical results for both of the PEM and *** mathematical statements are provided to demonstrate the equivalence of the PEM and PMPS bases as they are both bases of a certain polynomial vector ***,some numerical experiments were conducted to validate the implementation of the PEM and *** results demonstrated that the PEM is more accurate and well-conditioned than the PMPS and the multiple-scale technique is essential in these polynomial methods.

关键词： Pascal polynomial polynomial expansion method polynomial method of particular solutions collocation method multiple-scale technique

虚拟企业业务过程协同建模和在线优化方法研究

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系统仿真学报 2002年第9期14卷 1157-1160页

作者：闫如忠陈云张开涛方明伦上海大学CIMS与机器人中心上海200072

提出基于Internet/Intranet的敏捷虚拟企业业务过程协同建模、在线数据采集与分析、过程动态优化方法。在工作流和CSCW管理集成平台上,构建业务过程建模、管理、分析与优化这一闭环系统,实现过程的在线优化,支持虚拟企业业务过程不断改... 详细信息

提出基于Internet/Intranet的敏捷虚拟企业业务过程协同建模、在线数据采集与分析、过程动态优化方法。在工作流和CSCW管理集成平台上,构建业务过程建模、管理、分析与优化这一闭环系统,实现过程的在线优化,支持虚拟企业业务过程不断改进,适应动态企业内外环境的变化,为敏捷制造在企业的成功应用提供先进的方法和工具。

关键词：虚拟企业业务过程协同建模在线优化方法

一种基于硬件特征和动态许可证的移动App软件授权认证模型（英文）

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机床与液压 2016年第24期44卷 107-112页

作者：高博陈韵如罗江华肖灿重庆市教育考试院信息处重庆401147 重庆理工大学图书馆重庆400054

软件版权保护是知识产权保护体系中的重要组成部分。随着鱼洞互联网的快速发展,软件架构和授权正面临新的挑战。事实证明,目前移动互联网亟需一种新的软件保护机制。基于研究者前期的工作,分析了移动互联网的特性,将整个版权保护过程分... 详细信息

软件版权保护是知识产权保护体系中的重要组成部分。随着鱼洞互联网的快速发展,软件架构和授权正面临新的挑战。事实证明,目前移动互联网亟需一种新的软件保护机制。基于研究者前期的工作,分析了移动互联网的特性,将整个版权保护过程分为3个状态共8个步骤,提出了一种新的支持动态许可证的分布式移动App软件授权认证模型。与以前相关工作相比,新模型在在可行性、安全性和完备性等方面有许多优点。

关键词：移动互联网版权保护硬件特征动态许可证

Advances in Graphene‑Based Electrode for Triboelectric Nanogenerator

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Nano-Micro Letters 2025年第1期17卷 378-403页

作者： Bin Xie Yuanhui Guo yun chen Hao Zhang Jiawei Xiao Maoxiang Hou Huilong Liu Li Ma Xin chen Chingping Wong State Key Laboratory of Precision Electronic Manufacturing Technology and Equipment Guangdong University of TechnologyGuangzhou 510006People’s Republic of China School of Electromechanical Engineering Guangdong University of TechnologyGuangzhou 510006People’s Republic of China School of Materials Science and Engineering Georgia Institute of TechnologyAtlantaGA 30332USA

With the continuous development of wearable electronics,wireless sensor networks and other micro-electronic devices,there is an increasingly urgent need for miniature,flexible and efficient nanopower generation *** nanogenerator(TENG)technology can convert small mechanical energy into electricity,which is expected to address this *** the core component of TENG,the choice of electrode materials significantly affects its *** metal electrode materials often suffer from problems such as durability,which limits the further application of ***,as a novel electrode material,shows excellent prospects for application in TENG owing to its unique structure and excellent electrical *** review systematically summarizes the recent research progress and application prospects of TENGs based on graphene *** precision processing methods of graphene electrodes are introduced,and the applications of graphene electrode-based TENGs in various scenarios as well as the enhancement of graphene electrodes for TENG performance are *** addition,the future development of graphene electrode-based TENGs is also prospectively discussed,aiming to promote the continuous advancement of graphene electrode-based TENGs.

关键词： Triboelectric nanogenerator Precision processing Graphene electrode Self-powered sensor

Trinuclear gold-catalyzed site-selective alkylation of peptides

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Science China Chemistry 2025年第1期 249-256页

作者： Qing-yun Fang chengyihan Gu Yinghan chen Wencheng Yan Yong Liang Weipeng Li chengjian Zhu Jie Han Jin Xie State Key Laboratory of Coordination Chemistry Jiangsu Key Laboratory of Advanced Organic Materials Chemistry and Biomedicine Innovation Center (Chem BIC) School of Chemistry and Chemical Engineering Nanjing University Green Catalysis Center College of Chemistry Zhengzhou University State Key Laboratory of Natural Medicines China Pharmaceutical University

Selective modification of peptides has always been a challenging issue. The selective alkylation of peptides can alter the biological activity and physical properties of molecules, and it has gained significant research interest. We herein disclose an intriguing gold-catalyzed alkylation of peptides using bench-stable unactivated alkyl bromides under photoredox catalysis. A wide range of structurally diverse primary, secondary and tertiary alkyl bromides serve as effective coupling partners to precisely connect with the α-C(sp3)–H in glycine residue of peptides. This protocol demonstrates an exceptionally broad scope for alkyl halides and excellent tolerance for a wide range of useful functional groups. A series of relay transformations to construct cyclic peptides, to proceed click reaction and to realize peptide fluorescence labeling further enhance its synthetic practicality. In addition, mechanistic studies and density functional theory(DFT) calculations reveal an inner-sphere and subsequent outersphere single electron transfer(SET) mechanism.

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OCTA在无视网膜病变的糖尿病患者中应用的Meta分析

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国际眼科杂志 2022年第11期22卷 1836-1843页

作者：刘自强邓宇接传红王建伟宋小花陈韵如李媛媛中国中医科学院眼科医院中国北京市100040 北京中医药大学循证医学中心中国北京市100029

目的:采用Meta分析方法评价光学相干断层扫描血管成像(OCTA)在无视网膜病变的糖尿病(NDR)患者中的应用。方法:计算机检索CNKI、WanFang Data、VIP、CBM、PubMed、Embase数据库以查找相关研究,检索时间为建库至2021-10。两名研究者独立... 详细信息

目的:采用Meta分析方法评价光学相干断层扫描血管成像(OCTA)在无视网膜病变的糖尿病(NDR)患者中的应用。方法:计算机检索CNKI、WanFang Data、VIP、CBM、PubMed、Embase数据库以查找相关研究,检索时间为建库至2021-10。两名研究者独立筛选文献、提取资料,并采用NOS量表评价纳入研究质量,使用RevMan 5.3软件和STATA软件进行Meta分析和发表偏倚评价,对异质性较大的结果进行敏感性分析,确保结果的准确性。结果:共纳入44项研究,包括NDR患者2053例2600眼,健康对照组患者1775例2117眼,对黄斑中心凹无血管区(FAZ)面积、周长,FAZ旁300μm内的血流密度(FD300)、非圆指数(AI)、黄斑区血流密度(VD)、神经节细胞复合体(GCC)厚度和视网膜神经纤维层(RNFL)厚度等17个指标进行了Meta分析,Meta分析结果显示:NDR组的FAZ浅层毛细血管丛(SCP)、深层毛细血管丛(DCP)面积、周长均高于健康对照组,FD300、黄斑区VD,RNFL厚度均低于健康对照组(均P0.05)。结论:相比对健康对照组,NDR患者FAZ面积、周长增大,黄斑区VD、RNFL厚度降低,存在早期视网膜微血管损伤和神经退行性病变,OCTA可以作为DR早期诊断的辅助工具。

关键词：光学相干断层扫描血管成像(OCTA) 糖尿病无视网膜病变 Meta分析

姜黄素类似物L6H4对2型糖尿病大鼠肾脏的保护作用

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中国应用生理学杂志 2017年第1期33卷 11-15,I0001,I0002页

作者：刘曦马骏胡茂通董细丹项兰婷顾倩如杜转运陈三妹陈国荣浙江中医药大学附属温州市中医院肾内科温州325000 温州医科大学附属第一医院病理科浙江温州325015 温州医科大学检验医学与生命科学学院浙江温州325035 绍兴文理学院医学院浙江绍兴312000

目的:探讨姜黄素类似物L6H4对2型糖尿病大鼠肾脏的保护作用及机制。方法:24只SPF级雄性SD大鼠,随机分成3组(n=8):对照组(NC组)、糖尿病组(DM组)和糖尿病治疗组(DT组),采用高脂饮食加腹腔注射低剂量链脲佐菌素诱导2型糖尿病大鼠模型。DT... 详细信息

目的:探讨姜黄素类似物L6H4对2型糖尿病大鼠肾脏的保护作用及机制。方法:24只SPF级雄性SD大鼠,随机分成3组(n=8):对照组(NC组)、糖尿病组(DM组)和糖尿病治疗组(DT组),采用高脂饮食加腹腔注射低剂量链脲佐菌素诱导2型糖尿病大鼠模型。DT组按0.2 mg/kg·d剂量的L6H4灌胃8周。治疗结束后测24h尿蛋白、空腹血糖(FBG)、甘油三酯(TG)、血肌酐(Scr)、血尿素氮(BUN)、尿酸(UA)。采用光镜和透射电镜观察大鼠肾脏的形态学改变;用免疫组化法测定大鼠肾脏组织转化生长因子-β1(TGF-β1)、纤维粘连蛋白(FN)、四型胶原(Col-IV)的表达水平。结果:DM组大鼠24 h尿蛋白、FBG、TG、Scr、BUN均明显升高(P<0.01),肾小球体积增大、不规则,弥漫性系膜基质增多,伴基底膜不同程度的增生肥厚及足突融合现象;肾组织的TGF-β1、FN、Col-IV表达水平明显增加(P<0.05)。经L6H4治疗后,DT组的24 h尿蛋白、FBG、TG、Scr、BUN水平明显下降(P<0.01),大鼠肾小球形态较规则,系膜区基质明显减少,足细胞肿胀、融合现象减轻;肾组织的TGF-β1、FN、Col-IV表达明显减少(P<0.05)。结论:L6H4可能通过下调TGF-β1的表达,抑制FN、Col-IV的大量分泌,减轻细胞外基质的沉积,从而起到保护2型糖尿病大鼠肾脏的作用。

关键词：姜黄素类似物L6H4 2型糖尿病肾脏转化生长因子-β1 大鼠

Selective Acid Hydrolysis Condition for the Composition and Linkage with a Fructofuranosyl Backbone of a Polysaccharide from Angelica sinensis (Oliv) Diels

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Chinese Chemical Letters 2006年第10期17卷 1369-1372页

作者： Gui yun XU Yang chen ru Xian chen Institute of Chemistry Chinese Academy of Sciences Beijing 100080 Institute of Medicinal Biotechnology Chinese Academy of Medical Sciences Beijing 100050

A new polysaccharide was extracted and purified from the roots of Angelica sinensis （Oliv） Diels （ASD）. Its composition and linkage was elucidated by selective hydrolysis and GC/MS analysis of its derivatives. The polysaccharide was made of → 1） Fruf（2→and→6） Glcp （l→as its backbone with highly branched structure. To our best knowledge, this is the first report of the fructose residue in polysaccharides from the roots of the ASD.

关键词： Selective hydrolysis fructofuranosyl backbone GC/MS

Role of the Greenland Sea ice anomaly in the late-spring drought over Northwest China

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 1-5页

作者： Yang Liu Huopo chen Nansen-Zhu International Research Centre Institute of Atmospheric Physics Chinese Academy of SciencesBeijingChina Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University for Information Science and TechnologyNanjingChina

Drought across Northwest China in late spring has exerted a vital effect on the local climate and agricultural production,and has been alleviated during the past *** study explored the influence of the preceding Arctic sea ice on the May drought in Northwest China caused by the precipitation *** analysis indicated that when the Greenland Sea ice concentration is abnormally high during February to April,the dry conditions in Northwest China tend to be *** increase of sea ice in the Greenland Sea can excite a meridional circulation,which causes sea surface temperature(SST)anomalies in the North Atlantic via the sea-air interaction,manifested as significant warm SST anomalies over the south of Greenland and the subtropical North Atlantic,but negative SST anomalies over the west of the *** abnormal SST pattern maintains to May and triggers a zonal wave train from the North Atlantic through Scandinavia and Central Asia to Northwest China,leading to abnormal cyclones in Northwest ***,Northwest China experiences a more humid climate than usual.

关键词： Arctic sea ice Greenland Sea North Atlantic SST Drought Northwest China