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Darwinian rebel:The legacy of Loh-Seng tsai-Chinese animal psychologist

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Protein & Cell 2022年第10期13卷 701-706页

作者： Yong Wang Wei Chen Shiying Li Bin yin Center for Brain Mindand EducationShaoxing UniversityShaoxing 312000China School of Psychology Fujian Normal UniversityFuzhou 350108China

Loh-Seng tsai(蔡乐生,1901–1992)(Fig.1),the worldrenowned Chinese animal psychologist and psychopharmacologist,was born to a merchant family in Chaoan County,Guangdong Province on February 6th,*** was nominated for the Nobel Peace Prize in 1951 and *** Nixon praised his“exemplary academic achievements”in ***’s research in experimental psychology can be divided into two *** the first stage(1919–1949),tsai embarked on the path of psychology as a student under the guidance of Clarence Herbert ***,tsai expanded and popularized the experimental research conducted by comparative psychologist Zing-Yang Kuo(郭任远,1898–1970)and Harvey Carr,both of whom were tsai’s supervisors at different times.

关键词： logist Peace expanded

PESOI: Process Embedded Service-Oriented Architecture

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软件学报 2006年第6期17卷 1470-1484页

作者： Wei-Tek tsai Department of Computer Science and Engineering Arizona State University Tempe AZ 85281 USA

Service-Oriented Architecture (SOA) has drawn significant attention recently, and numerous architecture approaches have been proposed to represent SOA-based applications. The architecture of SOA-based applications is different from traditional software architecture, which is mainly static. The architecture of an SOA-based application is dynamic, i.e., the application can be composed at runtime using existing services, and thus the architecture is really determined at runtime, instead of design time. SOA applications have provided a new direction for software architecture study, where the architecture can be dynamically changed at runtime to meet the new application requirements. This paper proposes a Process-Embedded Service-Oriented Infrastructure to build SOA-based applications. This infrastructure embeds the entire software lifecycle management and service-oriented system engineering into the application developed on this infrastructure. Thus, the users can easily re-develop the applications during operation to meet the changing environments and requirements, through the supports provided by the embedded infrastructure.

关键词：服务导向处理服务导向体系软件体系结构分类

The Clumpy Structure of Five Star-bursting Dwarf Galaxies in the MaNGA Survey

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Research in Astronomy and Astrophysics 2024年第2期24卷 83-103页

作者： Mengting Ju Jun yin Lei Hao Chenxu Liu Chao-Wei tsai Junfeng Wang Zhengyi Shao Shuai Feng Yu Rong Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China University of Chinese Academy of Sciences Beijing 100049China Key Lab for Astrophysics Shanghai 200034China South-Western Institute for Astronomy Research Yunnan UniversityKunming 650500China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China Department of Astronomy Physics BuildingXiamen UniversityXiamenFujian 361005China College of Physics Hebei Normal UniversityShijiazhuang 050024China Hebei Key Laboratory of Photophysics Research and Application Shijiazhuang 050024China Department of Astronomy University of Science and Technology of ChinaHefei 230026China

The star-forming clumps in star-bursting dwarf galaxies provide valuable insights into understanding the evolution of dwarf *** this paper,we focus on five star-bursting dwarf galaxies featuring off-centered clumps in the Mapping Nearby Galaxies at Apache Point Observatory *** the stellar population synthesis software Fitting Analysis using Differential evolution Optimization,we obtain the spatially resolved distribution of the star formation history,which allows us to construct the g-band images of the five galaxies at different *** images can help us to probe the evolution of the morphological structures of these *** images of a stellar population older than 1 Gyr are typically smooth,images of a stellar population younger than 1 Gyr reveal significant clumps,including multiple clumps which appear at different locations and even different *** study the evolutionary connections of these five galaxies to other dwarf galaxies before their star-forming clumps appear,we construct the images of the stellar populations older than three age nodes,and define them to be the images of the"host"*** find that the properties such as the central surface brightness and the effective radii of the hosts of the five galaxies are in between those of dwarf ellipticals(dEs)and dwarf irregulars(dIrrs),with two clearly more similar to dEs and one more similar to *** the five galaxies,8257-3704 is particularly interesting,as it shows a previous starburst event that is not quite visible from its gri image,but only visible from images of the stellar population at a few hundred million *** star-forming clump associated with this event may have appeared at around 600 Myr ago and disappeared at around 40 Myr ago.

关键词： galaxies dwarf-galaxies evolution-galaxies formation-Galaxy structure

Recovery and stabilization of heavy metal sludge (Cu and Ni) from etching and electroplating plants by electrolysis and sintering

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Science China Chemistry 2009年第5期52卷 644-651页

作者： tsai LungChang tsai FangChang Graduate School of Environment and Safety Engineering National Yunlin University of Science and Technology Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials Hubei University Faculty of Material Science and Engineering Hubei University

This work dealt with the recovery and stabilization of the sludge with heavy metals (Cu and Ni) produced from etching and electroplating plants. The heavy metals in the sludge were deprived of by acid leaching, followed by precipitation with 28% NH4OH, and finally by electrolysis. In the electrolysis, the recovery percentage and purity were investigated at different electronic currency and temperature. The metal-deprived sludge was stabilized by mixing with glass powder and clay, followed by sintering at high temperature. How the ratio of glass powder to metal-deprived sludge affected final products (sludge bricks) was explored, in terms of specific gravity, absorption capacity, unconfined compressive strength, morphology, the volume shrinkage ratio and burn-up ratio. The volume shrinkage ratio and burn-up ratio of sludge bricks increased with metal-deprived sludge contents. The heavy metal remaining in sludge bricks was assessed through TCLP (toxicity characteristic leaching procedure) and by the analysis of SEM and EDX. The results from TCLP showed that the contents of leached metals were all below the regulatory criteria. This fact approved the feasibility of our method.

关键词： heavy metal sludge treatment stability electrolysis brick material toxicity characteristic leaching procedure (TCLP)

Erlotinib combination with a mitochondria-targeted ubiquinone effectively suppresses pancreatic cancer cell survival

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World Journal of Gastroenterology 2024年第7期30卷 714-726页

作者： Pui-yin Leung Wenjing Chen Anissa N Sari Poojitha Sitaram Pui-Kei Wu Susan tsai Jong-In Park Department of Biochemistry Medical College of WisconsinMilwaukeeWI 53226United States Department of Surgery Medical College of WisconsinMilwaukeeWI 53226United States

BACKGROUND Pancreatic cancer is a leading cause of cancer-related *** activity of the epidermal growth factor receptor(EGFR)is often observed in pancreatic cancer,and the small molecule EGFR inhibitor erlotinib has been approved for pancreatic cancer therapy by the food and drug ***,erlotinib alone is ineffective and should be combined with other drugs to improve therapeutic *** previously showed that certain receptor tyrosine kinase inhibitors can increase mitochondrial membrane potential(Δψm),facilitate tumor cell uptake ofΔψm-sensitive agents,disrupt mitochondrial homeostasis,and subsequently trigger tumor cell *** has not been tested for this *** To determine whether erlotinib can elevateΔψm and increase tumor cell uptake ofΔψm-sensitive agents,subsequently triggering tumor cell ***Δψm-sensitive fluorescent dye was used to determine how erlotinib affectsΔψm in pancreatic adenocarcinoma(PDAC)cell *** viability of conventional and patient-derived primary PDAC cell lines in 2D-and 3D cultures was measured after treating cells sequentially with erlotinib and mitochondria-targeted ubiquinone(MitoQ),aΔψm-sensitive *** synergy between erlotinib and MitoQ was then analyzed using SynergyFinder *** preclinical efficacy of the twodrug combination was determined using immune-compromised nude mice bearing PDAC cell line *** Erlotinib elevatedΔψm in PDAC cells,facilitating tumor cell uptake and mitochondrial enrichment ofΔψm-sensitive *** triggered caspase-dependent apoptosis in PDAC cells in culture if used at high doses,while erlotinib pretreatment potentiated low doses of *** suggested that these drugs synergistically induced tumor cell *** with in vitro data,erlotinib and MitoQ combination suppressed human PDAC cell line xenografts in mice more effectively than single treatments of each *** Our findings suggest tha

关键词： Pancreatic cancer Erlotinib Mitochondria-targeted ubiquinone Mitochondria Combination therapy

Exploring the electromagnetic information of metasurfaces

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National Science Review 2020年第12期7卷 1845-1846页

作者： Din-Ping tsai Department of Electronic and Information Engineering The Hong Kong Polytechnic University

Metasurfaces,a 2D counterpart of metamaterials,are made of planar subwavelength-scale meta-atoms with designed *** meta-atoms of a metasurface can be used to couple incident waves to free space with controllable amplitudes,phases and polarizations,yielding many novel photonic devices such as optical meta-lenses[1–4].In recent years,with the bloom of information technologies,

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Higher-mode effect on the seismic responses of buildings with viscoelastic dampers

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Earthquake Engineering and Engineering Vibration 2002年第1期1卷 119-129页

作者： Meng-Hao tsai Department of Civil Engineering Taiwan UniversityChinese Taipei Postdoctoral Research Fellow

In conventional modal analysis procedures,usually only a few dominant modes are required to describe the dynamic behavior of multi-degrees-of-freedom *** number of modes needed in the dynamic analysis depends on the higher-mode contribution to the structural response,which is called the higher-mode *** modal analysis approach, however,may not be directly applied to the dynamic analysis of viscoelastically damped *** is because the dynamic properties of the viscoelastic dampers depend on their vibration ***,the structural stiffness and damping contributed from those dampers would be different for each *** this study,the higher-mode effect is referred to as the response difference induced by the frequency-dependent property of viscoelastic dampers at higher *** analysis procedures for buildings with viscoelastic dampers distributed proportionally and non-proportionally to the stiffness of the buildings are developed to consider the higher-mode *** studies on shear-type viscoelastically damped building models are conducted to examine the accuracy of the proposed procedures and to investigate the significance of the higher-mode effect on their seismic *** damper models are used to estimate the peak damper forces in the proposed procedures. Study results reveal that the higher-mode effect is significant for long-period viscoelastically damped *** higher-mode effect on base shear is less significant than on story acceleration *** difference of the seismic response usually occurs at the top ***,the higher-mode effect may not be reduced by decreasing the damping ratio provided by the viscoelastic *** practical application,it is realized that the linear viscous damping model without considering the higher-mode effect may predict larger damper forces and hence,is on the conservative side.

关键词： model analysis viscoelastic dampers higher-mode effect

A novel multisignature scheme for a special verifier group against clerk and rogue-key attacks

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Journal of Zhejiang University-Science C(Computers and Electronics) 2010年第4期11卷 290-295页

作者： Jia-lun tsai Tzong-chen WU Kuo-yu tsai Department of Information Management National Taiwan University of Science and Technology Taiwan Information Security Center National Taiwan University of Science and Technology

The digital signature is a very important subject for network *** multiple signers and multiple verifiers,Xie and Yu(2004) pointed out that the multisignature scheme of Laih and Yen(1996) is vulnerable to a harmful *** attack can occur when a specified group of verifiers cooperate to forge a multisignature by secret key substitution following the leak of a secret key or by group public key adjustment during the process of renewing *** and Yu proposed an improvement of Laih and Yen's multisignature *** this paper,we show that Xie and Yu's scheme is vulnerable to clerk and rogue-key *** propose an improved multisignature scheme to resist such *** the proposed scheme,multiple signers can generate a multisignature for the message with the signers' secret keys,and the specified group of verifiers can cooperate to verify the validity of the multisignature with the signers' public keys and the verifiers' secret *** proposed scheme for a special verifier group not only has the advantages of Xie and Yu's scheme,but also is secure against clerk and rogue-key attacks.

关键词： Multisignature Clerk attack Rogue-key attack Cryptosystem

Ca_(1−x)Li_(x)Al_(1−x)Si_(1+x)N_(3):Eu^(2+) solid solutions as broadband,color-tunable and thermally robust red phosphors for superior color rendition white light-emitting diodes

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Light(Science & Applications) 2016年第1期5卷 465-473页

作者： Le Wang Rong-Jun Xie Yuanqiang Li Xiaojun Wang Chong-Geng Ma Dong Luo Takashi Takeda Yi-Ting tsai ru-Shi Liu Naoto Hirosaki College of Optics and Electronic Science and Technology China Jiliang UniversityHangzhouZhejiang 310018China College of Materials Xiamen UniversityXiamenFujian 361005China Sialon Group National Institute for Materials Science(NIMS)TsukubaIbaraki 305-0044Japan Intematix Corporation FremontCA 94538USA College of Sciences Chongqing University of Posts and TelecommunicationsChongqing 400065China Department of Chemistry Taiwan University Department of Mechanical Engineering and Graduate Institute of Manufacturing Technology Taipei University of Technology

Color rendition,luminous efficacy and reliability are three key technical parameters for white light-emitting diodes(wLEDs)that are dominantly determined by down-conversion ***,there is usually an inevitable trade-off between color rendition and luminescence efficacy because the spectrum of red phosphor(that is,spectral broadness and position)cannot satisfy them *** this work,we report a very promising red phosphor that can minimize the aforementioned trade-off via structure and band-gap engineering,achieved by introducing isostructural LiSi_(2)N_(3) into CaAlSiN_(3):Eu^(2+).The solid solution phosphors show both substantial spectra broadening(88→117 nm)and blueshift(652→642 nm),along with a significant improvement in thermal quenching(only a 6%reduction at 150℃),which are strongly associated with electronic and crystal structure *** broadband and robust red phosphor thus enables fabrication of super-high color rendering wLEDs(Ra=95 and R9=96)concurrently with the maintenance of a high-luminous efficacy(101 lm W^(−1)),validating its superiority in highperformance solid state lightings over currently used red phosphors.

关键词： color rendering LEDs nitride phosphor structure disorder