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Diffusion of Innovative Behavior of the Public Toward Preparing FEMKs:From Innovative Characteristics to Personal Risk Perception and Behavioral Intention

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Psychosomatic Medicine Research 2021年第1期3卷 16-23页

作者： Shu-Xian Xu Ting-Yu Duan Shu-Ting Wei Xi-Zhe He ru-yi hou yi-Bo Wu School of pharmacy Shenyang pharmaceutical universityBenxi 117004China Department of humanities arts and mediaChangzhi Medical CollegeChangzhi 046000China Department of clinical medicine School of Basic MedicineShandong UniversityJinan 250100China School of pharmacy Jiangxi University of Traditional Chinese MedicineNanchang 330004China Key Research Base of Philosophy and Social Sciences in Shaanxi Province Health Culture Research Center of ShaanxiXi'an 712046China Peking University Health Science Center Beijing 100191China

Objective:The study aims to apply diffusion of innovation theory and structural equation modeling(SEM)to explore the current situation of personal risk perception and preparation of family emergency medicine kits(FEMKs)in Shanxi Province during the period of ***,the study intends to analyze the impact of innovation characteristics and risk perception to provide reference for the future popularization of FEMKs and the formulation of relevant ***:A total of 1,606 permanent residents in Shanxi Province were selected as *** was used to analyze the relationship among innovation characteristics,personal risk perception,and behavioral ***:The results demonstrate that only observability(λ=0.968)exerted a significant direct impact on the public's behavior of preparing *** risk perception(λ=0.334)can have a significant direct impact on behavioral *** advantage,compatibility,and convenience of use exerted significant impacts on behavioral intention by influencing individual perceived risk(mediating effects=0.237,0.892,and 1.044,respectively).Conclusion:Residents are undergoing a period of change(i.e.,from the contemplation to the preparation stage).Thus,innovative characteristics can directly influence the behavior or behavioral intention of preparing FEMKs by influencing the public's risk *** the future,studies should focus on publicity and education of the behavior of preparing FEMKs to increase the awareness of residents and effectively improve the FEMKs level of importance given to this behavior.

关键词： COVID-19 Emergency medicine kit Diffusion of innovations Structural equation model Psychosomatic medicine Affecting factors

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Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion

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Neural Regeneration Research 2025年第10期20卷 2838-2854页

作者： Lu Guan Mengting Qiu Na Li Zhengxiang Zhou ru Ye Liyan Zhong Yashuang Xu Junhui Ren yi Liang Xiaomei Shao Jianqiao Fang Junfan Fang Junying Du Department of Neurobiology and Acupuncture Research Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Key Laboratory for Research of Acupuncture Treatment and Transformation of Emotional Diseases Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Fuchun Community Health Service Center of Fuyang District HangzhouZhejiang ProvinceChina

Pain is often comorbid with emotional disorders such as anxiety and *** of the anterior cingulate cortex has been implicated in pain and pain-related negative emotions that arise from impairments in inhibitory gamma-aminobutyric acid *** review primarily aims to outline the main circuitry(including the input and output connectivity)of the anterior cingulate cortex and classification and functions of different gamma-aminobutyric acidergic neurons;it also describes the neurotransmitters/neuromodulators affecting these neurons,their intercommunication with other neurons,and their importance in mental comorbidities associated with chronic pain *** understanding on their role in pain-related mental comorbidities may facilitate the development of more effective treatments for these ***,the mechanisms that regulate gamma-aminobutyric acidergic systems remain *** is also unclear as to whether the mechanisms are presynaptic or *** exploration of the complexities of this system may reveal new pathways for research and drug development.

关键词： anterior cingulate cortex anxiety chronic pain circuit communication comorbidity depression gamma-aminobutyric acidergic neurons parvalbumin neurons synaptic transmission

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Preparation and photo-catalytic activity of TiO_2-coated medical stone-based porous ceramics

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International Journal of Minerals,Metallurgy and Materials 2013年第6期20卷 593-597页

作者： ru-qin Gao Xin-mei hou School of Environmental and Municipal Engineering North China University of Water Resources and Electric Power School of Metallurgical and Ecological Engineering University of Science and Technology Beijing

Medical stone-based porous ceramics as a carrier were prepared by ultra-fine grinding and low-temperature sintering method. Nano-TiO~ thin films were loaded on the carrier by chemical liquid deposition method using titanium tetrachloride as a precursor. The micro-morphology and microstructure of the synthesized samples were characterized using X-ray diffraction, scanning electron microscopy with energy dispersive spectrometry, and mercury injection method. The photo-catalytic activity of the TiO2 thin films was investigated by degrading formaldehyde. The main crystalline phase in the TiO2 thin films calcined at 550~C is anatase with the average particle size about 10 nm. The specific surface area of the carrier-coated nano-TiO2 increases from 3.68 to 5.32 m2/g. The formaldehyde removal rate of the TiO2/medical stone-based porous ceramics irradiated under an ultraviolet lamp for 120 min reaches 85.6%.

关键词： porous materials ceramics medical stone titanium dioxide thin films formaldehyde photocatalysis

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基于CLIP模型和知识数据库的零样本动作识别

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天津大学学报（自然科学与工程技术版） 2025年第1期58卷 91-100页

作者：侯永宏郑皓春高嘉俊任懿天津大学电气自动化与信息工程学院天津300072 天津大学未来技术学院天津300072 中国科学院软件研究所北京100190

零样本动作识别旨在从已知类别的动作样本数据中学习知识,并将其迁移到未知的动作类别上,从而实现对未知动作样本的识别和分类.现有的零样本动作识别模型依赖有限的训练数据,可学习到的先验知识有限,难以将视觉特征准确地映射到语义标签... 详细信息

零样本动作识别旨在从已知类别的动作样本数据中学习知识,并将其迁移到未知的动作类别上,从而实现对未知动作样本的识别和分类.现有的零样本动作识别模型依赖有限的训练数据,可学习到的先验知识有限,难以将视觉特征准确地映射到语义标签上,是限制零样本学习性能提升的关键因素.针对上述问题,本文提出了一种引入外部知识数据库和CLIP模型的零样本学习框架,利用多模态CLIP模型通过自监督对比学习方式积累的知识,来扩充零样本动作识别模型的先验知识.同时,设计了时序编码器,以弥补CLIP模型时序建模能力的欠缺.为了使模型学习到更丰富的语义特征,缩小视觉特征和语义标签之间的语义鸿沟,本文扩展了已知动作类别的语义标签,用更为详细的描述语句代替简单的文本标签,丰富了文本表示的语义信息;在此基础上,在模型外部构建了一个知识数据库,在不增加模型参数规模的条件下为模型提供额外的辅助信息,强化视觉特征与文本特征表示之间的关联关系.最后,本文遵循零样本学习规范,对模型进行微调,使其适应零样本动作识别任务,提高了模型的泛化能力.所提方法在HMDB51和UCF101两个主流数据集上进行了广泛实验,实验数据表明,该方法的识别性能相比目前的先进方法在上述两个数据集上分别提升了3.8%和2.3%,充分体现了所提方法的有效性.

关键词：零样本学习动作识别 CLIP模型知识数据库

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Efficacy and prognostic factors of neoadjuvant chemotherapy for triple-negative breast cancer

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World Journal of Clinical Cases 2022年第12期10卷 3698-3708页

作者： Feng Ding ru-Yue Chen Jun hou Jing Guo Tian-yi Dong Department of General Surgery Shandong Provincial HospitalCheeloo College of MedicineShandong UniversityJinan 250021Shandong ProvinceChina Department of Breast and Thyroid Surgery Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina Department of Anesthesiology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina

BACKGROUND Breast cancer mainly occurs in young and premenopausal women;its incidence is increasing annually. Patients with triple-negative breast cancer(TNBC) have relatively high recurrence and transfer rates during the operation and 3 years after postoperative adjuvant chemotherapy. Currently, the treatment for patients with TNBC is mainly based on a comprehensive combination of surgery and chemotherapy. Therefore, identifying additional effective treatments to improve patient prognosis is *** To explore and discuss the effects and prognostic factors of neoadjuvant chemotherapy in *** In total, 118 patients diagnosed with TNBC from January 2016 to January 2020 in our hospital were selected and divided into the observation(n = 60) and control(n = 58) groups according to therapeutic regimen. The control group received routine chemotherapy, and the observation group received neoadjuvant chemotherapy. The therapeutic effects of the two groups were observed, and the survival of patients was followed *** The karyopherin A2(KPNA2)-positive and SRY-related HMG box-2(SOX2)-positive expression rates of patients with TNBC with intravascular tumor thrombus and tumor-node-metastasis(TNM) stage IV were 92.00% and 91.67% and 96.00% and 95.83%, respectively, which were significantly higher than those of patients with no intravascular tumor thrombus and TNM stage Ⅲ(P < 0.05). KPNA2 was positively associated with SOX2 expression(rs = 0.514, P < 0.50). The short-term curative effect of the observation group was better than that of the control group(P < 0.05), and the total effective rate was 58.33%. After treatment, carcinoembryonic antigen, cancer antigen(CA) 19-9, and CA125 Levels in the observation group were 11.40 ± 2.32 mg/L, 19.92 ± 3.42 kU/L, and 54.30 ± 12.28 kU/L, respectively, which were significantly lower than those in the control group(P < 0.05). The median survival time of the observation group was 33 mo(95%CI: 31.21-34.79), which was signifi

关键词： Neoadjuvant chemotherapy Triple-negative breast cancer Clinical effect Prognosis Influencing factor

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Some new integral inequalities for conjugate A-harmonic tensors

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Applied Mathematics(A Journal of Chinese Universities) 2008年第1期23卷 43-50页

作者： GAO Hong-ya hou Lan-ru College of Math. and Comput. Sci. Hebei University Baoding 071002 China. Mathematics Study Center of Hebei Province Shijiazhuang 050016 China. Beijing Science Technology and Management College Beijing 100086 China.

A new kind of weight-Ar^λ3 （λ1, λ2, Ω）-weight is used to prove the local and global integral inequalities for conjugate A-harmonic tensors, which can be regarded as generalizations of the classical results. Some... 详细信息

关键词： conjugate A-harmonic tensor Ar^λ3 (λ1 λ2 Ω)-weight weighted inequality quasiregular mapping.

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Immunotherapeutic strategies targeting B cell maturation antigen in multiple myeloma

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Military Medical Research 2021年第3期8卷 433-443页

作者： yi Fang Jian hou Department of Hematology Renji HospitalSchool of MedicineShanghai Jiao Tong University160 Pujian RoadShanghai 200127China

Multiple myeloma(MM) is the second most common hematologic malignancy, and is characterized by the clonal expansion of malignant plasma cells. Despite the recent improvement in patient outcome due to the use of novel therapeutic agents and stem cell transplantation, all patients eventually relapse due to clone evolution. B cell maturation antigen(BCMA) is highly expressed in and specific for MM cells, and has been implicated in the pathogenesis as well as treatment development for MM. In this review, we will summarize representative anti-BCMA immune therapeutic strategies, including BCMA-targeted vaccines, anti-BCMA antibodies and BCMA-targeted CAR cells. Combination of different immunotherapeutic strategies of targeting BCMA, multi-target immune therapeutic strategies, and adding immune modulatory agents to normalize anti-MM immune system in minimal residual disease(MRD) negative patients, will also be discussed.

关键词： B cell maturation antigen Multiple myeloma Vaccine Antibody CAR T-cells

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Influence of Liquid Isoprene rubber on Strain Softening of Carbon Black Filled Isoprene rubber Nanocomposites

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Chinese Journal of Polymer Science 2021年第7期39卷 887-895页

作者： Feng-yi hou yi-Hu Song Qiang Zheng MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou 310027China

The reinforcement of rubbers by nanoparticles is always accompanied with enhanced dissipation of mechanical energy upon large *** for solving the contradiction between improving reinforcement and reducing energy dissipation for rubber nanocomposites have not been well *** carbon black(CB)filled isoprene rubber(IR)/liquid isoprene rubber(LR)blend nanocomposites with similar crosslink density(ve)are prepared and influence of LR on the strain softening behaviors including Payne effect under large amplitude shear deformation and Mullins effect under cyclic uniaxial deformation is *** introduction of LR could improve the frequency sensitivity of loss modulus and reduce critical strain amplitude for Payne effect and loss modulus at the low ***,tuning ve and LR content allows reducing mechanical hysteresis in Mullins effect without significant impact on the mechanical *** investigation is illuminating for manufacturing nanocomposite vulcanizates with balanced mechanical hysteresis and reinforcement effect.

关键词： rubber nanocomposites Stress softening Mechanical hysteresis Liquid rubber

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Relationship Between Myocardial Injury and Expression of PGC-1α and Its Coactivators in Chronic Keshan Disease

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Current Medical Science 2022年第1期42卷 85-92页

作者： Shuai JIANG Qian-ru YE Rong-xia ZHEN Juan-niu ZHANG yi-yi ZHANG Xu LIU Jie hou Institute of Keshan Disease Chinese Center for Endemic Disease ControlHarbin Medical UniversityHarbin 150081China Affiliated Hospital of Jilin Medical College Jilin 132013China Hangzhou Center for Disease Control and Prevention Hangzhou 310021China Sanya Institute of Technology Sanya 572022 China Inner Mongolia Autonomous Region Mental Health Center Hohhot010010China

Objective:Keshan disease(KD)is a mitochondrial *** present study explored the roles of peroxisome proliferator-activated receptor(PPAR)-y coactivator-la(PGC-la),the key regulator of mitochondrial structure and function,and its coactivators in myocardial injury in chronic ***,the usefulness of these molecules in the diagnosis of chronic KD was assessed.

关键词： Keshan disease peroxisome proliferator-activated receptor-y coactivator-la myocardial injury lactate dehydrogenase

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Transport patterns and numerical simulation of heavy metal pollutants in soils of lead–zinc ore mines

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Journal of Mountain Science 2021年第9期18卷 2345-2356页

作者： CAO Jie XIE Cheng-yu hou Zhi-ru College of Environment and Resources Xiangtan UniversityXiangtan 411105China School of Metallurgy and Environment Central South UniversityChangsha 410083China

Exploring transport patterns of soil contaminants is essential for solving the problem of heavy metal contamination in mine *** this study,contamination of Pb,Zn,and Cd in the mountain soils of the lead–zinc ore mines in Ganxi Township,Hengdong County,Hunan Province,China was investigated,and their transport patterns were further explored using a soil-column model and numerical simulation *** total,111 mine soil samples were collected and placed into six experimental soil *** controlling the water flow,a control soil column group(CK),two mixed soil columns X1 with daily water flows of 1 and 5 L,and three mixed soil columns X3 with daily water flows of 2,3,and 4 L were *** results showed that the residual fraction of Pb accounted for 71.93%of the content on average,whereas the exchangeable fractions of Zn,Cd,and Fe-Mn oxide-bound fractions of Zn and Cd accounted for 28.60%,31.07%,and 43.2%and 53.54%of the content,***,Zn,and Cd in the soils of the CK,X1,and X3 groups mainly were accumulated at a depth from approximately 0 to 20 cm,and the content at this depth accounted for 60.09%of that at a 0~40 cm *** soil at a depth range of 0~10 cm was most seriously contaminated,and the proportion of content was 32.39%of that at a 0~40 cm *** simulation showed that on the 5 th day,the pollutant transport range was 0~24 cm,and on the 9 th day,the pollutant transport range exceeded 40 *** the 15 th day,the transport capacity of pollutants at depths of 0~40 cm was close to the stable state,but the soil at a depth of 0~10 cm was still heavily *** results reflect the transport pattern of heavy metal pollutants in the soil of lead–zinc ore mines and may provide a reliable scientific support for the prevention of heavy metal contamination in mine environments.

关键词： Mountain Mine soil Heavy metals Numerical simulations Pollutants Transport patterns

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