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Sustainability-oriented prioritization of nuclear fuel cycle transitions in China:a holistic MCDM framework under uncertainties

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Nuclear Science and Techniques 2024年第9期35卷 196-212页

作者： Lei Wang ru-xing gao Hyo On Nam Hong Jang Won Il Ko Chun-Dong Zhang Guo-An Ye Wen-Heng Jing State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China School of Energy Science and Engineering Nanjing Tech UniversityNanjing 211816China Korea Atomic Energy Research Institute 989-111 Daedeok-daeroYuseong-GuDaejeon 34057Republic of Korea China Institute of Atomic Energy P.O.Box 275-1Beijing 102413China

A sustainability-oriented assessment of the nuclear energy system can provide informative and convincing decision-making support for nuclear development strategies in *** our previous study,four authentic nuclear fuel cycle(NFC)transi-tion scenarios were proposed,featuring different development stages and exhibiting distinct environmental,economic,and technical ***,because of the multiple and often conflicting criteria embedded therein,determining the top-priority NFC alternative for a sustainability orientation remains *** address this issue,this study proposed a novel hybrid multi-criteria decision-making framework comprising fuzzy AHP,PROMETHEE GAIA,and ***,an improved fuzzy AHP weighting model was developed to determine criteria weights under uncertainty and investigate the influence of various weight aggregation and defuzzification ***,PROMETHEE GAIA was used to address conflicts among the criteria and prioritize alternatives on a visualized k-dimensional GAIA *** a result,the alternative for direct recycling PWR spent fuel in fast reactors is considered the most ***,a sensitivity analysis was conducted to examine the influence of criteria weight variation and validate the screening ***,using MOORA,some significant optimization ideas and valuable insights were provided to support decision-makers in shaping nuclear development strategies.

关键词： Nuclear energy systems Nuclear fuel cycle Fuzzy AHP PROMETHEE GAIA

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Boosted solar water oxidation steered by atomically precise alloy nanocluster

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Chinese Chemical Letters 2025年第1期36卷 349-354页

作者： Xian Yan Huawei Xie gao Wu Fang-xing Xiao College of Materials Science and Engineering Fuzhou University(New Campus)Minhou 350108China Department of Forensic Science The Engineering Research CenterFujian Police CollegeFuzhou 350002China State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China

Atomically precise metal nanoclusters(NCs)have been deemed as a new generation of metal nanomaterials in the field of solar energy conversion due to their unique atomic stacking manner,quantum confinement effects,light-harvesting capability and multitude of active ***,wide-spread application of monometallic NCs is blocked by the ultrashort carrier lifespan,uncontrollable charge transport pathway,and light-induced poor stability,impeding the construction of robust and stable metal NC-based ***,we report the fabrication of stable alloy(Au_(1-x)Pt_(x))NCs photosystem,for which tailor-made negatively charged l-glutathione(GSH)-capped Au_(1-x)Pt_(x)NCs as the building blocks are controllably deposited on the Bi VO_(4)(BVO)by a self-assembly approach for steering enhanced light absorption and interfacial charge transfer over alloy NCs-based photoanodes(Au_(1-x)Pt_(x)/BVO).The self-assembled Au_(1-x)Pt_(x)/BVO composite photoanode exhibits the significantly enhanced photoelectrochemical water oxidation performances compared with pristine BVO and Au_(x)/BVO photoanodes,which is caused by the Pt atom doping into the Au_(x)NCs for elevating photosensitivity and boosting the *** synergy of Au and Pt atoms in alloy NCs protects the gold core from rapid oxidation,improving the photostability and accelerating the surface charge transfer *** work would significantly inspire ongoing interest in unlocking the charge transport characteristics of atomically precise alloy NCs for solar energy conversion.

关键词： Alloy nanoclusters Self-assembly Charge transport Photoanodes Photoelectrochemical water oxidation

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A comprehensive review of deactivation and modification of selective catalytic reaction catalysts installed in cement kilns

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Journal of Environmental Sciences 2025年第2期148卷 451-467页

作者： Yang Zheng Yi xing Guoliang Li Jiajia gao rui Li Qi Liu Tao Yue School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing 100083China State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

After the ultralow emission transformation of coal-fired power plants,cement production became China’s leading industrial emission source of nitrogen *** gas dust contents at the outlet of cement kiln preheaters were as high as 80-100 g/m^(3),and the calcium oxide content in the dust exceeded 60%.Commercial V_(2)O_(5)(-WO3)/TiO_(2) catalysts suitable for coal-fired flue gas suffer from alkaline earth metal Ca poisoning of cement kiln flue *** studies have also identified the poisoning of cement kiln selective catalytic reaction(SCR)catalysts by the heavy metals lead and *** of the poisoning process is the primary basis for analyzing the catalytic *** review summarizes and analyzes the SCR catalytic mechanism and chronicles the research progress concerning this poisoning *** on the catalytic and toxification mechanisms,it can be inferred that improving the anti-poisoning performance of a catalyst enhances its acidity,surface redox performance-active catalytic sites,and shell layer *** data provide support in guiding engineering practice and reducing operating costs of SCR ***,future research directions for SCR denitrification catalysts in the cement industry are *** study provides critical support for the development and optimization of poisoning-resistant SCR denitrification catalysts.

关键词： Cement Flue Gas NH_(3)-SCR CaO Poisoning Mechanism Anti-poisoning Modification

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Efficient conversion of chitin to HMF under the cocatalytic system of formic acid and silicotungstic acid

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Journal of Oceanology and Limnology 2025年第1期43卷 261-273页

作者： Luxiao ZHOU Kun gao Peng HE Huahua YU Ronge xing Song LIU Yukun QIN College of Chemistry and Molecular Engineering Qingdao University of Science and TechnologyQingdao 266042China CAS and Shandong Province Key Laboratory of Experimental Marine Biology Institute of OceanologyChinese Academy of SciencesQingdao 266071China Laboratory for Marine Drugs and Bioproducts Qingdao Marine Science and Technology CenterQingdao 266237China

The conversion process of chitin,one of the abundant biomass resources on the earth,not only follows the principles of green chemistry,but also has significant value in industrial ***,it is a great challenge to directly convert insoluble and rigid structured chitin to 5-hydroxymethylfurfural(HMF).To address this issue,we developed a green conversion process combining pretreatment and catalytic *** was first pretreated by hexafluoro isopropanol(HFIP),which somewhat disrupted the hydrogen bonding network within the chitin ***,formic acid(FA)and silicotungstic acid(STA)synergistically catalyzed the conversion to HMF in a biphasic system of 2-methyltetrahydrofuran(2-Me-THF)/H2O,and high yields(40.2%)HMF was obtained under the optimism *** product distribution was analyzed by HPLC-MS and the co-catalysis of FA with STA was evidenced.A dual-function catalytic system with both Lewis and Br?nsted acids was created,the catalytic system that significantly improved the efficiency of complex tandem catalytic reactions with *** on the experimental results,a possible pathway for chitin conversion was deduced,providing a new catalytic idea for the efficient conversion of chitin to HMF.

关键词： chitin 5-hydroxymethylfurfural 2-Me-THF/H2O biphasic system Lewis and Br?nsted acid

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Unraveling the role of long non‑coding RNAs in chronic heat stress‑induced muscle injury in broilers

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Journal of Animal Science and Biotechnology 2025年第1期16卷 206-217页

作者： Zhen Liu Yingsen Liu Tong xing Jiaolong Li Lin Zhang Liang Zhao Yun Jiang Feng gao College of Animal Science and Technology Key Laboratory of Animal Origin Food Production and Safety Guarantee of Jiangsu ProvinceJiangsu Collaborative Innovation Center of Meat Production and ProcessingQuality and Safety ControlNanjing Agricultural UniversityNanjing 210095People’s Republic of China Anhui Key Laboratory of Livestock and Poultry Product Safety Engineering Institute of Animal Husbandry and Veterinary MedicineAnhui Academy of Agricultural SciencesHefei 230031China Institute of Agro‑Products Processing Jiangsu Academy of Agricultural SciencesNanjing 210014People’s Republic of China School of Food Science and Pharmaceutical Engineering Nanjing Normal UniversityNanjing 210023People’s Republic of China

Background Chronic heat stress(CHS)is a detrimental environmental stressor with a negative impact on the meat quality of ***,the underlying mechanisms are not fully *** study investigates the effects of CHS on long non-coding RNA(lncRNA)expression and muscle injury in broilers,with a focus on its implications for meat *** The results showed that CHS diminished breast muscle yield,elevated abdominal fat deposition,induced cellular apoptosis(P<0.05),and caused *** analysis revealed 151 differentially expressed(DE)lncRNAs when comparing the normal control(NC)and HS groups,214 DE lncRNAs when comparing the HS and PF groups,and 79 DE lncRNAs when comparing the NC and pair-fed(PF)*** eliminating the confounding effect of feed intake,68 lncRNAs were identified,primarily associated with cellular growth and death,signal transduc-tion,and metabolic ***,the apoptosis-related pathway P53,lysosomes,and the fibrosis-related gene TGF-β2 were significantly upregulated by *** These findings indicate that chronic heat stress induces cellular apoptosis and muscle injury through lncRNA,leading to connective tissue accumulation,which likely contributes to reduced breast muscle yield and meat quality in broilers.

关键词： Apoptosis Broiler Chronic heat stress LncRNA Muscle

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针刺对干眼兔泪腺形态学及泪腺上皮细胞凋亡相关基因蛋白表达的影响

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眼科新进展 2017年第3期37卷 210-214页

作者：陈星如高卫萍南京中医药大学江苏省南京市210029

目的探讨针刺对干眼兔泪腺形态学及泪腺上皮细胞凋亡相关基因蛋白表达的影响,分析针刺对干眼的作用机制。方法取健康新西兰白兔18只随机分为空白组、模型组、针刺组,每组6只,空白组不作任何处理;模型组皮下注射氢溴酸东莨菪碱,每天4次,... 详细信息

目的探讨针刺对干眼兔泪腺形态学及泪腺上皮细胞凋亡相关基因蛋白表达的影响,分析针刺对干眼的作用机制。方法取健康新西兰白兔18只随机分为空白组、模型组、针刺组,每组6只,空白组不作任何处理;模型组皮下注射氢溴酸东莨菪碱,每天4次,每次2 mg·kg^(-1)共24 d;针刺组在与模型组同样处理的基础上进行针刺,每天1次,共14 d。不同时段观察各组泪液分泌试验检测泪液量的结果,光镜、电镜观察泪腺形态学变化,免疫组织化学检测泪腺组织中凋亡相关基因蛋白的表达。结果泪液分泌试验检测泪液量结果显示在针刺第4、7、14天同时段针刺组与模型组相比明显升高,差异均有统计学意义(均为P0.05)。光镜、电镜示针刺组泪腺上皮细胞胞浆丰富,排列紧密,活动良好,与空白组接近。免疫组织化学检测显示与模型组比较,针刺组泪腺导管及腺泡上皮细胞中Bax的阳性细胞半定量评分值明显低,差异有统计学意义(P0.05)。与空白组相比,针刺组Bax、Bcl-2评分值差异均无统计学意义(均为P>0.05)。与模型组比较,针刺组的泪腺导管及腺泡上皮细胞中Fas、FasL的阳性细胞半定量评分值明显低,差异均有统计学意义(均为P0.05)。结论针刺通过抑制干眼兔泪腺组织的细胞凋亡及腺体萎缩,促进兔干眼模型的泪腺代谢,从而达到增加泪液分泌的作用。

关键词：针刺干眼泪腺细胞凋亡

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Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury

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Neural Regeneration Research 2025年第2期20卷 587-597页

作者： Tong Li Hui-Min xing Hai-Dong Qian Qiao gao Sheng-Lan Xu Hua Ma Zai-Long Chi State Key Laboratory of Ophthalmology Optometry and Visual ScienceEye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina

Several studies have found that transplantation of neural progenitor cells(NPCs)promotes the survival of injured ***,a poor integration rate and high risk of tumorigenicity after cell transplantation limits their clinical *** extracellular vesicles(sEVs)contain bioactive molecules for neuronal protection and *** studies have shown that stem/progenitor cell-derived sEVs can promote neuronal survival and recovery of neurological function in neurodegenerative eye diseases and other eye *** this study,we intravitreally transplanted sEVs derived from human induced pluripotent stem cells(hiPSCs)and hiPSCs-differentiated NPCs(hiPSC-NPC)in a mouse model of optic nerve *** results show that these intravitreally injected sEVs were ingested by retinal cells,especially those localized in the ganglion cell *** with hiPSC-NPC-derived sEVs mitigated optic nerve crush-induced retinal ganglion cell degeneration,and regulated the retinal microenvironment by inhibiting excessive activation of *** analysis further revealed that hiPSC-NPC derived sEVs transported neuroprotective and anti-inflammatory miRNA cargos to target cells,which had protective effects on RGCs after optic nerve *** findings suggest that sEVs derived from hiPSC-NPC are a promising cell-free therapeutic strategy for optic neuropathy.

关键词： exosome miRNA neural progenitor cell neurodegeneration neuroinflammation neuroprotection optic nerve crush optic neuropathy retinal ganglion cell small extracellular vesicles

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Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model

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中华医学杂志(英文版) 2025年第2期138卷 2024 Dec 23页

作者： Tu xing Zou Zixing Li Jiahui Zeng Simiao Luo Zhengchao Li Gen gao Yuanxu Zhang Kang Guangzhou Institutes of Biomedicine and Health Chinese Academy of Sciences Guangzhou Guangdong China Guangzhou National Laboratory Guangzhou International Bio Island Guangzhou Guangdong China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangzhou Guangdong China University of Chinese Academy of Sciences Beijing China Guangzhou Women and Children’s Medical Center Guangzhou Medical University Guangzhou Guangdong China Department of Big Data and Biomedical AI College of Future Technology Peking University Beijing China Institute for Artificial Intelligence in Medicine and Faculty of Medicine Macau University of Science and Technology Macao Special Administrative Region China

Background: Retinal ganglion cell (RGC) death caused by acute ocular hypertension is an important characteristic of acute glaucoma. Receptor-interacting protein kinase 3 (RIPK3) that mediates necroptosis is a potential therapeutic target for RGC death. However, the current understanding of the targeting agents and mechanisms of RIPK3 in the treatment of glaucoma remains limited. Notably, artificial intelligence (AI) technologies have significantly advanced drug discovery. This study aimed to discover RIPK3 inhibitor with AI ***: An acute ocular hypertension model was used to simulate pathological ocular hypertensionin vivo. We employed a series of AI methods, including large language and graph neural network models, to identify the target compounds of RIPK3. Subsequently, these target candidates were validated using molecular simulations (molecular docking, absorption, distribution, metabolism, excretion, and toxicity [ADMET] prediction, and molecular dynamics simulations) and biological experiments (Western blotting and fluorescence staining)in vitro andin ***: AI-driven drug screening techniques have the potential to greatly accelerate drug development. A compound called HG9-91-01, identified using AI methods, exerted neuroprotective effects in acute glaucoma. Our research indicates that all five candidates recommended by AI were able to protect the morphological integrity of RGC cells when exposed to hypoxia and glucose deficiency, and HG9-91-01 showed a higher cell survival rate compared to the other candidates. Furthermore, HG9-91-01 was found to protect the retinal structure and reduce the loss of retinal layers in an acute glaucoma model. It was also observed that the neuroprotective effects of HG9-91-01 were highly correlated with the inhibition of PANoptosis (apoptosis, pyroptosis, and necroptosis). Finally, we found that HG9-91-01 can regulate key proteins related to PANoptosis, indicating that this compound exerts neuroprotective e

关键词： Virtual screening AI model PANoptosis acute ocular hypertension HG9-91-01 Glucoma

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基于粒子群算法的电动汽车有序充电控制策略的研究

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电力学报 2017年第3期32卷 194-199,264页

作者：余星儒高桂革上海电机学院电气学院上海200240

大规模电动汽车接入电力系统时,就会使得电力负荷的峰谷差和功率波动产生的巨大的影响,更严重的,还会超过电力系统的供电能力和承受能力,给电网的安全稳定运行带来巨大的挑战。在此背景下,首先对电动汽车充电负荷的影响因素进行了分析,... 详细信息

大规模电动汽车接入电力系统时,就会使得电力负荷的峰谷差和功率波动产生的巨大的影响,更严重的,还会超过电力系统的供电能力和承受能力,给电网的安全稳定运行带来巨大的挑战。在此背景下,首先对电动汽车充电负荷的影响因素进行了分析,根据电动汽车的充电特性建立起电动汽车充电负荷的模型。然后,基于粒子群算法对模型进行优化求解,使得电网负荷的峰谷差最小,约束条件为负荷波动和充电电量限制。通过仿真,与无序充电的情况做出对比,有序充电在平滑负荷波动,降低电网的峰谷差的方面有很好的"削峰填谷"的作用。

关键词：电动汽车有序充电粒子群算法充电负荷模型

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Effect of order–disorder transition on thermodynamic and electronic properties of σ and χ phases in W–Re alloy: the first-principles calculation

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Tungsten 2025年第1期7卷 195-213页

作者： Zhi-Peng Zhu Dian Jia William Yi Wang Jun-Lei Yin xing-Yu gao Shu-Feng Yang Hai-Feng Song Jin-Shan Li State Key Laboratory of Solidification Processing Northwestern Polytechnical University Laboratory of Computational Physics Institute of Applied Physics and Computational Mathematics School of Metallurgical and Ecological Engineering University of Science and Technology Beijing

The Tungsten-Rhenium(W-Re) alloys,celebrated for their high melting point,strength at elevated temperatures,electrical resistivity,and radiation resistance,have been widely utilized in high-temperature components,aerospace,electronics,and nuclear *** constituents of the topologically close-packed(TCP) phases,the sigma phase(σ) and chi phase(χ) formed within W-Re alloys wield considerable influence on the mechanical properties and the stability of the *** calculations were utilized in the present work to explore the structural,thermodynamic,and electronic properties of both ordered and disordered configurations within the σ and χ phases,culminating in a systematic elucidation of the higher phase stability exhibited by the ordered *** is found that the bulk modulus of these two phases is directly proportional to the concentration of Re in the alloy,while the equilibrium volume is inversely *** thermodynamic parameters of the σ and χ phases are calculated via the mean-field potential *** similar trends observed in the isobaric heat capacity,enthalpy increment,and entropy change curves for these two phases suggest they possess comparable thermodynamic *** is noteworthy that the contribution of ionic vibrations predominantly affects the isobaric heat capacity,while the contribution of thermal electronic excitations increases linearly with *** the structure and thermodynamic properties of TCP phases in W-Re alloys at low temperatures has profound significance for optimizing material performance,microstructures features,establishing theoretical foundations,and predicting material behavior.

关键词： First-principles calculations Phase stability TCP phases Thermodynamic properties W–Re alloy

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