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Influence of Sub-Cloud Secondary Evaporation Effects on the Stable Isotopes in Precipitation of Urumqi Glacier No.1,Eastern Tianshan

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Journal of Earth Science 2024年第1期35卷 177-189页

作者： Mengyuan Song Zhongqin li Feiteng Wang xin Zhang State Key Laboratory of Cryospheric Sciences Northwest Institute of Eco-Environment and ResourcesTianshan Glaciological StationChinese Academy of SciencesLanzhou 730000China College of Geography and Environmental Science Northwest Normal UniversityLanzhou 730000China College of Sciences Shihezi UniversityShihezi 832000China

In arid regions,the stable hydrogen and oxygen isotopic composition in raindrops is often modified by sub-cloud secondary evaporation when they descend from cloud base to ground through the unsaturated *** a result of kinetic fractionation,the slope and intercept of the δ^(2)H-δ^(18)O correlation equation *** variation of deuterium excess from cloud base to the ground is often used to quantitatively evaluate the influence of secondary evaporation effect on isotopes in *** on the event-based precipitation samples collected at Urumqi Glacier No.1,eastern Tianshan during four-year observation,the existence and impact of secondary evaporation effects were analyzed by the methods of isotope-evaporation *** high air temperature,small raindrop diameter and precipitation amount,and low relative humidity conditions,the remaining rate of raindrops is small and the change of deuterium excess is large relatively,and the slope and intercept of δ^(2)H-δ^(18)O correlation equation are much lower than those of Global Meteoric Water line,which mean that the influence secondary evaporation on precipitation *** on the conditions of low air temperature,high relative humidity,heavy rainfall,and large raindrop diameter,the change of deuterium excess is small relatively and the remaining rate of raindrops is large,and the slope and intercept of δ^(2)H-δ^(18)O correlation equation increase,the secondary evaporation is *** isotope-evaporation model described a good linear correlation between changes of deuterium excess and evaporation proportion with the slope of 0.90‰/%,which indicated that an increase of 1%in evaporation may result in a decrease of deuterium excess about 0.90‰.

关键词： stable isotopes meteoric water line deuterium excess sub-cloud secondary evaporation effect precipitation glaciers

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Height and body mass index trajectories from 1975 to 2015 and prevalence of stunting,underweight and obesity in 2016 among children in Chinese cities:findings from five rounds of a national survey

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World Journal of Pediatrics 2024年第4期20卷 404-412页

作者： xin‑Nan Zong Hui li Ya‑Qin Zhang Department of Growth and Development Capital Institute of PediatricsBeijing 100020China

Background A more comprehensive assessment of growth and nutrition in children is required in China due to rapid socioeconomic *** aimed to investigate height and body mass index(BMI)trajectories from 1975 to 2015 and the prevalence of stunting and obesity in 2016 among children in Chinese *** A total of 904,263 children from birth to 6.9 years were collected from a series of nationally representative surveys in *** and BMI trajectories and prevalence of stunting,underweight,overweight and obesity were *** The average height level of Chinese urban children under 7 years presented a positive secular trend from 1975 to 2015;however,a slowing tendency occurred in 2005‒*** apparent increase was observed at the 5th,50th and 95th percentiles of BMI in urban children aged 3 years and older,with a more prominent increase at the 95th *** total prevalence of stunting and underweight under 7 years was 1.4%and 2.0%,*** total prevalence of overweight and obesity under 7 years was 12.6%and 4.3%,respectively,with 12.7%and 4.9%for boys,12.6%and 3.6%for girls,12.1%and 4.0%in urban areas and 13.1%and 4.5%in suburban rural *** The average height level of Chinese urban children has reached World Health Organization child growth standards since 2005 and presented a slowing tendency in secular trend in 2005‒*** attention and efforts and public health interventions should be urgently made to combat overweight and obesity among preschool children.

关键词： Body mass index Children Height Obesity Stunting

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Berberine alleviates ovarian tissue damage in mice with hepatolenticular degeneration by suppressing ferroptosis and endoplasmic reticulum stress

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Journal of Integrative Medicine 2024年第4期22卷 493-502页

作者： Qian-zhuo liu Hui Han xin-ru Fang Lu-yao Wang Dan Zhao Miao-zhu Yin Nian Zhang Peng-yu Jiang Zhi-hui Ji li-min Wu Department of Neurology the First Affiliated Hospital of Anhui University of Chinese MedicineHefei 230031Anhui ProvinceChina Center for Reproduction and Genetics the First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230031Anhui ProvinceChina

Objective:Hepatolenticular degeneration (HLD) is an autosomal recessive disorder that manifests as multiorgan damage due to impaired copper (Cu) metabolism. Female patients with HLD often experience reproductive impairments. This study investigated the protective effect of berberine against ovarian damage in toxic-milk (TX) mice, a murine model for ***:Mice were categorized into control group, HLD TX group (HLD group), penicillamine (Cu chelator)-treated TX group and berberine-treated TX group. Body weight, ovary weight and the number of ovulated eggs were recorded. Follicular morphology and cellular ultrastructure were examined. Total iron, ferrous iron (Fe2+) and trivalent iron (Fe3+) levels, as well as malondialdehyde (MDA), glutathione(GSH) and oxidized glutathione (GSSG), were measured in the ovaries. Western blot analysis was used to analyze the expression of proteins related to ferroptosis and endoplasmic reticulum (ER) ***:Ovarian tissue damage was evident in the HLD group, with a significant increase in ferroptosis and ER stress compared to the control group. This damage was inhibited by treatment with penicillamine,a Cu chelator. Compared with the HLD group, berberine increased the number of ovulations, and improved ovarian morphology and ultrastructure. Further, we found that berberine reduced total iron,Fe2+, MDA and GSSG levels, elevated GSH levels, decreased the expression of the ferroptosis marker protein prostaglandin-endoperoxide synthase 2 (PTGS2), and increased glutathione peroxidase 4 (GPX4)expression. Furthermore, berberine inhibited the expression of ER stress-associated proteins mediated by the protein kinase RNA-like ER kinase (PERK) ***:Ferroptosis and ER stress are involved in Cu-induced ovarian damage in TX mice. Berberine ameliorates ovarian damage in HLD TX mice by inhibiting ferroptosis and ER stress.

关键词： Berberine Hepatolenticular degeneration Copper deposition Ferroptosis Endoplasmic reticulum stress

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Spacelike Framed Curves with lightlike Components and Singularities of Their Evolutes and Focal Surfaces in Minkowski 3-space

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Acta Mathematica Sinica,English Series 2024年第6期40卷 1521-1532页

作者： Peng Cheng li Dong He PEI xin ZHAO School of Mathematics and Statistics Northeast Normal UniversityChangchun 130024P.R.China Department of Mathematics Harbin Institute of TechnologyWeihai 264209P.R.China School of Mathematics and Statistics Qingdao UniversityQingdao 266071P.R.China

In this paper,we define the evolute and focal surface of a spacelike framed curve with lightlike components in Minkowski *** is a generalization of the previous results of regular spacelike curves,since singularities are allowed in the original spacelike curves studied by spacelike framed curves with lightlike ***,we show a new geometric invariant to characterise singularities of the focal ***,the classification theorem and recognition theorem for the singularities of the focal surface in generic are also given.

关键词： Evolutes focal surfaces spacelike framed curves singularities

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A Bird’s Eye View of Quantitative Proteome of Tumor Tissues from Lung Cancer Patients by a High Precision Mass Spectrometry Method

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Chemical Research in Chinese Universities 2024年第1期40卷 136-144页

作者： DU Xiaohui li Encheng WANG Qi YOU xin Lung Cancer Transitional Medicine Center The Second Affiliated Hospital of Dalian Medical UniversityDalian116023P.R.China Department of Scientific Research Center The Second Affiliated Hospital of Dalian Medical UniversityDalian116023P.R.China Department of Respiratory Medicine The Second Affiliated Hospital of Dalian Medical UniversityDalian116023P.R.China

Lung cancer produces a high incidence of malignant *** have been many studies on lung cancer using mass spectrometry(MS)***,most studies have focused on humoral *** this work,26 pairs of tissue samples(tumor ***-tumor)from patients with lung cancer were analyzed using liquid chromatography-tandem MS(LC-MS/MS)with data-independent acquisition *** total,3152 proteins were quantified from tissue samples with high confidence,including 189 up-regulated and 522 down-regulated proteins(tumor ***-tumor).In addition,79 and 690 proteins were identified only in para-cancerous samples and cancerous samples,*** results from bio-informatics tools indicated that altered proteins like PEBP1,HRG and LYZ could be ideal reservoirs for screening the potential biomarkers for lung *** is believed these tissue-specific proteomics results will assist in the studies of lung cancer.

关键词： Lung cancer Proteome Data-independent aquisition

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Tumor necrosis factor α deficiency promotes myogenesis and muscle regeneration

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Zoological Research 2024年第4期45卷 951-960页

作者： Yu Fu Jing-ru Nie Peng Shang Bo Zhang Da-Wei Yan xin Hao Hao Zhang State Key Laboratory of Animal Biotech Breeding China Agricultural UniversityBeijing 100193China College of Animal Science Xizang Agricultural and Animal Husbandry UniversityLinzhiXizang 860000China College of Animal Science and Technology Yunnan Agricultural UniversityKunmingYunnan 650201China

Tumor necrosis factorα(TNFα)exhibits diverse biological functions;however,its regulatory roles in myogenesis are not fully *** the present study,we explored the function of TNFαin myoblast proliferation,differentiation,migration,and myotube fusion in primary myoblasts and C2C12 *** this end,we constructed TNFαmuscle-conditional knockout(TNFα-CKO)mice and compared them with flox mice to assess the effects of TNFαknockout on skeletal *** indicated that TNFα-CKO mice displayed phenotypes such as accelerated muscle development,enhanced regenerative capacity,and improved exercise endurance compared to flox mice,with no significant differences observed in major visceral organs or skeletal *** label-free proteomic analysis,we found that TNFα-CKO altered the distribution of several muscle development-related proteins,such as Hira,Casz1,Casp7,Arhgap10,Gas1,Diaph1,Map3k20,Cfl2,and Igf2,in the nucleus and *** set enrichment analysis(GSEA)further revealed that TNFαdeficiency resulted in positive enrichment in oxidative phosphorylation and MyoD targets and negative enrichment in JAK-STAT *** findings suggest that TNFα-CKO positively regulates muscle growth and development,possibly via these newly identified targets and pathways.

关键词： TNFα Muscle-conditional knockout Myogenesis Regeneration Muscle development

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A GMDA clustering algorithm based on evidential reasoning architecture

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Chinese Journal of Aeronautics 2024年第1期37卷 300-311页

作者： Haibin WANG xin GUAN Xiao YI Shuangming li Guidong SUN Naval Aviation University Yantai 264001China Unit 92941 of PLA Huludao 125001China Institute of Systems Engineering Beijing 100082China

The traditional clustering algorithm is difficult to deal with the identification and division of uncertain objects distributed in the overlapping region,and aimed at solving this problem,the Evidential Clustering based on General Mixture Decomposition Algorithm(GMDA-EC)is ***,the belief classification of target cluster is carried out,and the sample category of target distribution overlapping region is ***,on the basis of General Mixture Decomposition Algorithm(GMDA)clustering,the fusion model of evidence credibility and evidence relative entropy is constructed to generate the basic probability assignment of the target and achieve the belief division of the ***,the performance of the algorithm is verified by the synthetic dataset and the measured *** experimental results show that the algorithm can reflect the uncertainty of target clustering results more comprehensively than the traditional probabilistic partition clustering algorithm.

关键词： Evidential clustering Credal partition Evidential reasoning Mixed decomposition Gaussian mixture model

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Comparison of tailpipe carbonyls and volatile organic compounds emissions from in-use gasoline/CNG bi-fuel vehicles

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Journal of Environmental Sciences 2024年第1期135卷 619-629页

作者： Jiachen li Yunshan Ge xin Wang Mengzhu Zhang Haohao Wang School of Mechanical Engineering Beijing Institute of TechnologyBeijing 100081China

Ground-level ozone contamination has been globally an urban air quality issue,particularly for China,which has recently made significant progress in purifying its *** exhaust emissions from motor vehicles,predominantly carbonyls and volatile organic compounds(VOCs),are among the leading contributors to ozone *** this chassislevel study,the unregulated emissions from five China-5 certified gasoline/CNG bi-fuel taxis,along with their ozone forming potential(OFP),were *** is found that carbonyls and VOCs were mainly emitted during the starting phase no matter the engine was cold or *** to gasoline,CNG fueling reduced VOCs emissions on a large scale,especially in the starting phase,but had elevated *** a fleet average,CNG fueling derived 15%and 46%less OFP than gasoline in cold-and hot-start tests,*** contributed to over 90%of the total OFP of the *** terms of alleviating ground-level ozone contamination,CNG is a feasible alternative to gasoline on light-duty vehicles.

关键词： CNG Gasoline Carbonyls VOCs OFP

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Laminar Flame Instability of n-Hexane,n-Octane,and n-Decane in Spherical Expanding Flames

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Journal of Thermal Science 2024年第3期33卷 1189-1199页

作者： YIN Geyuan HU Erjiang li Xiaotian LV xin HUANG Zuohua State Key Laboratory of Multiphase Flow in Power Engineering Xi’an Jiaotong UniversityXi’an710049China United Automotive Electronic Systems Co. LtdShanghai201206China Chongqing Changan Automobile Co. Ltd.Chongqing401120China

This paper focuses on the laminar flame instability of three high molecular weight n-alkanes,namely n-hexane,n-octane,and *** experiment was carried out in a constant volume combustion bomb to get the flame *** critical radius under different conditions was extracted using the image processing *** with the existing critical Peclet number theory,the dominant factors of flame instability under current conditions for three n-alkanes can be figured ***,the average cell size(equivalent cell radius,R_(cell))was extracted to provide quantitative analysis of the flame cellular structure,based on the method developed in this *** theoretical R_(cell)were also calculated and compared with the experimental results to validate the proposed method.

关键词： cellular instability equivalent cell radius critical Peclet number spherical flame

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Microfluidic-oriented synthesis of enriched iridium nanodots/carbon architecture for robust electrocatalytic nitrogen fixation

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Green Energy & Environment 2024年第3期9卷 544-555页

作者： Hengyuan liu xingjiang Wu Yuhao Geng xin li Jianhong Xu The State Key Laboratory of Chemical Engineering Department of Chemical EngineeringTsinghua UniversityBeijing100084China

Electrocatalytic nitrogen reduction reaction(NRR)is considered as a promising candidate to achieve ammonia synthesis because of clean electric energy,moderate reaction condition,safe operating process and harmless ***,the chemical inertness of nitrogen and poor activated capacity on catalyst surface usually produce low ammonia yield and faradic ***,the microfluidic technology is proposed to efficiently fabricate enriched iridium nanodots/carbon *** to in-situ co-precipitation reaction and microfluidic manipulation,the iridium nanodots/carbon nanomaterials possess small average size,uniform dispersion,high conductivity and abundant active sites,producing good proton activation and rapid electrons transmission and moderate adsorption/desorption *** a result,the as-prepared iridium nanodots/carbon nanomaterials realize large ammonia yield of 28.73 μg h^(-1) cm^(-2) and faradic efficiency of 9.14%in KOH ***,the high ammonia yield of 11.21 μg h^(-1) cm^(-2) and faradic efficiency of 24.30%are also achieved in H_(2)SO_(4) *** microfluidic method provides a reference for large-scale fabrication of nano-sized catalyst materials,which may accelerate the progress of electrocatalytic NRR in industrialization field.

关键词： Iridium nanodots Carbon Microfluidic technology Efficient synthesis Electrocatalytic nitrogen fixation

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