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Parotid metastasis of rare lung adenocarcinoma:A case report

World Journal of Clinical Cases 2024年第6期12卷 1182-1189页

作者： ru-xi yan Lin-Bo Dou Zi-Jia Wang Xue Qiao Hong-Hai Ji yan-Cong Zhang School of Stomatology Weifang Medical UniversityWeifang 261000Shandong ProvinceChina Department of Stomatology Dezhou People’s HospitalDezhou 253000Shandong ProvinceChina Department of Stomatology Dezhou Women and Children's HospitalDezhou 253000Shandong ProvinceChina

BACKGROUND Lung cancer(LC)is the leading cause of malignancy-related deaths *** most common sites of metastasis include the nervous system,bone,liver,respiratory system,and adrenal *** metastasis in the parotid gland is very rare,and its diagnosis presents a ***,we report a case of parotid metastasis in primary *** SUMMARY The patient was a 74-year-old male who was discovered to have bilateral facial asymmetry inadvertently two years *** right earlobe was slightly swollen and without pain or *** tomography(CT)examination showed bilateral lung space-occupying *** biopsy was performed and revealed adenocarcinoma(right-upper-lung nodule tissue).Positron emission tomography-CT examination showed:(1)Two hypermetabolic nodules in the right upper lobe of the lung,enlarged hy-permetabolic lymph nodes in the right hilar and mediastinum,and malignant space-occupying lesion in the right upper lobe of the lung and possible metastasis to the right hilar and mediastinal lymph nodes;and(2)multiple hypermetabolic nodules in bilateral parotid *** puncture biopsy was performed considering lung adenocarcinoma *** detection of lung biopsy specimens revealed an EGFR gene 21 exon L858R *** This case report highlights the challenging diagnosis of parotid metastasis in LC given its rare *** lesions should be differentiated from primary tumors of the parotid *** radiological imaging is unreliable,and puncture biopsy is needed for final diagnosis of this condition.

关键词： Lung cancer Metastasis Parotid gland Pathology Positron emission tomography/computed tomography Case report

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区间量测下基于无迹变换的伯努利粒子滤波算法

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控制与决策 2017年第8期32卷 1523-1527页

作者：吴孙勇张馨方桂丛楠蔡如华孙希延桂林电子科技大学数学与计算科学学院广西桂林541004 广西精密导航技术与应用重点实验室广西桂林541004 中国电子科技集团公司第五十四研究所石家庄050081

针对区间量测下目标的实时检测与跟踪问题,提出基于无迹变换的伯努利粒子滤波算法(BernoulliUpf).该算法在伯努利粒子滤波算法(Bernoulli-pf)的基础上融合无迹卡尔曼滤波(UKF),融合后的算法在预测步骤产生持续存活粒子时,充分考虑到当... 详细信息

针对区间量测下目标的实时检测与跟踪问题,提出基于无迹变换的伯努利粒子滤波算法(BernoulliUpf).该算法在伯努利粒子滤波算法(Bernoulli-pf)的基础上融合无迹卡尔曼滤波(UKF),融合后的算法在预测步骤产生持续存活粒子时,充分考虑到当前时刻的量测,从而引导粒子向高似然区域移动,使得粒子分布更加接近真实状态的后验分布.仿真实验表明,Bernoulli-Upf算法的估计精度优于Bernoulli-pf算法.

关键词：目标跟踪区间量测伯努利滤波无迹卡尔曼滤波粒子滤波

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miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong Jing-Jing Hu yan Yu xiao-Li Li xiao-Ting Sun Li-Ting Wang xia Wu Ling-Jie Zhu xiao-Jia yang Qian-ru He Fei Ding Hai-yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

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指向高质量课堂的听评课量表设计及其关键问题

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教学与管理 2025年第1期 24-28页

作者：户艳茹方妍清华大学教育研究院北京100084 清华大学附属中学北京100084

在建设高质量课堂的时代背景下,重新设计课堂听评课框架与维度,有助于倒逼教师专业成长,反促课堂提质增效。在深刻反思现有听评课量表存在不足、尤其是缺乏科学量化标准的前提下,重新设计的旨在提升课堂质量的听评课量表主要包括2个观... 详细信息

在建设高质量课堂的时代背景下,重新设计课堂听评课框架与维度,有助于倒逼教师专业成长,反促课堂提质增效。在深刻反思现有听评课量表存在不足、尤其是缺乏科学量化标准的前提下,重新设计的旨在提升课堂质量的听评课量表主要包括2个观察维度、6个观察要素、13个观察指标和26个观察点。在教学实践中应用这一听评课量表,需要注意凸显学生的主体性、全面性与个性化,构建民主平等的课堂生命共同体,展现时代风格与学校特色,形成良性教研文化和沟通合作机制。

关键词：高质量课堂听评课量表教研制度

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Deciphering Water Oxidation Catalysts: The Dominant Role of Surface Chemistry over Reconstruction Degree in Activity Promotion

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NANO-MICRO LETTERS 2025年第1期17卷 1-15页

作者： An, Li Li, Jianyi Sun, Yuanmiao Zhu, Jiamin Seow, Justin Zhu Yeow Zhang, Hong Zhang, Nan xi, Pinxian Xu, Zhichuan J. yan, Chun-Hua Lanzhou Univ Frontiers Sci Ctr Rare Isotopes Key Lab Nonferrous Met Chem & Resources Utilizat G State Key Lab Appl Organ ChemColl Chem & Chem Eng Lanzhou 730000 Peoples R China Nanyang Technol Univ Sch Mat Sci & Engn Singapore 639798 Singapore Chinese Acad Sci Fac Mat Sci & Energy Engn Shenzhen Inst Adv Technol Inst Technol Carbon Neutral Shenzhen 518055 Peoples R China Yunnan Univ Natl Ctr Int Res Photoelect & Energy Mat Electron Microscopy Ctr Sch Mat & EnergyKey Lab Electromagnet Mat & Devic Kunming 650091 Peoples R China Baotou Res Inst Rare Earths State Key Lab Baiyunobo Rare Earth Resource Res & Baotou 014030 Peoples R China Peking Univ Beijing Natl Lab Mol Sci State Key Lab Rare Earth Mat Chem & Applicat PKU HKU Joint Lab Rare Earth Mat & Bioinorgan Chem Beijing 100871 Peoples R China

Demonstrate that the key factor to determine the activity of reconstructed surfaces is the surface chemistry, instead of reconstruction degree using the popular perovskite LaNi1-xFexO3 oxides as model *** content can influence both the surface reconstruction degree, the activation degree, and the activity of reconstructed *** oxygen evolution reaction activity of reconstructed catalysts is primarily governed by the chemistry of the reconstructed surface species. Water splitting hinges crucially on the availability of electrocatalysts for the oxygen evolution reaction. The surface reconstruction has been widely observed in perovskite catalysts, and the reconstruction degree has been often correlated with the activity enhancement. Here, a systematic study on the roles of Fe substitution in activation of perovskite LaNiO3 is reported. The substituting Fe content influences both current change tendency and surface reconstruction degree. LaNi0.9Fe0.1O3 is found exhibiting a volcano-peak intrinsic activity in both pristine and reconstructed among all substituted perovskites in the LaNi1-xFexO3 (x = 0.00, 0.10, 0.25, 0.50, 0.75, 1.00) series. The reconstructed LaNi0.9Fe0.1O3 shows a higher intrinsic activity than most reported NiFe-based catalysts. Besides, density functional theory calculations reveal that Fe substitution can lower the O 2p level, which thus stabilize lattice oxygen in LaNi0.9Fe0.1O3 and ensure its long-term stability. Furthermore, it is vital interesting that activity of the reconstructed catalysts relied more on the surface chemistry rather than the reconstruction degree. The effect of Fe on the degree of surface reconstruction of the perovskite is decoupled from that on its activity enhancement after surface reconstruction. This finding showcases the importance to customize the surface chemistry of reconstructed catalysts for water oxidation.

关键词： Oxygen evolution reaction Perovskite oxides Doping Activation and reconstruction

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Potassium ions and cyano group modified g-C3N4 for effective generation of H2O2 through two-electron oxygen reduction

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Science China Chemistry 2025年第1期 192-200页

作者： Dongying Wang Shulan Pu Yongmin Chen Ke Lei Yujie Duan Linjiao Mao Xuhui Zeng xi Luo Yuntao Zhang Yuqin Dong Jin Zhong Zhang yan Sun School of Mechanical Engineering Chengdu University Department of Chemistry and Biochemistry University of California

Potassium ions （K+） doped graphitic carbon nitride （g-C3N4） was prepared by a thermal etching method using potassium hydroxide （KOH） as an ion *** transform infrared spectroscopy （FTIR） and X-ray photoelectron spectroscopy （XPS）results showed that the generation of the cyano group was detected while introducing K+.Under simulated sunlight irradiation,the sample with a K+doping amount of 10%showed the highest hydrogen peroxide （H2O2） generation rate of2,140.2μmol *** apparent quantum yield （AQY） at 400 nm and the solar-to-chemical conversion （SCC） are 4.35%and1.23%,respectively.K+acted as a bridge between g-C3N4layers,which enhanced charge transfer ***,the cyano group enhanced the adsorption capacity of protons （H+） and promoted the yield of *** catalyst exhibited excellent photocatalytic stability based on four-cycle *** addition,a mechanism study showed that superoxide radicals （·O2-）were the most important active species in the reaction *** production of H2O2was achieved through consecutive single-electron *** study deepens the understanding of the oxygen reduction reaction process and opens up a new venue for improving H2O2generation.

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Color Image Super-Resolution and Enhancement with Inter-Channel Details at Trivial Cost

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Journal of Computer Science & Technology 2020年第4期35卷 889-899页

作者： Chuang-Ye Zhang yan Niu Tie-ru Wu xi-Ming Li College of Computer Science and Technology Jilin UniversityChangchun 130012China Key Laboratory of Symbolic Computer and Knowledge Engineering of Ministry of Education Jilin University Changchun 130012China School of Mathematics Jilin UniversityChangchun 130012China

Image super-resolution is essential for a variety of applications such as medical imaging,surveillance imaging,and satellite imaging,among ***,the most popular color image super-resolution is performed in each color channel *** this paper,we show that the super-resolution quality can be further enhanced by exploiting the cross-channel *** by the High-Quality Linear Interpolation(HQLI)demosaicking algorithm by Malvar et al.,we design an image super-resolution scheme that integrates intra-channel interpolation with cross-channel details by isotropic linear *** its simplicity,our super-resolution method achieves the accuracy comparable with the existing fastest state-of-the-art super-resolution algorithm at 20 times faster *** is well applicable to applications that adopt traditional interpolations,for improved visual quality at trivial computation *** comparative study verifies the effectiveness and efficiency of the proposed super-resolution algorithm.

关键词： image super-resolution isotropic linear interpolation inter-channel detail enhancement low cost

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A binary study of color-magnitude diagrams of 12 globular clusters

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Research in Astronomy and Astrophysics 2010年第2期10卷 135-141页

作者： Zhong-Mu Li Cai-yan Mao ru-Heng Li ru-xi Li Mao-Cai Li College of Physics and Electronic Information Dali University Dali 671003 China National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China

Binary stars are common in star clusters and galaxies, but the detailed ef- fects of binary evolution are not taken into account in some color-magnitude diagram （CMD） studies. This paper studies the CMDs of twelve globular clusters via binary- star stellar populations. The observational CMDs of the star clusters are compared to those of binary-star populations, and then the stellar metallicities, ages, distances and reddenings of these star clusters are obtained. The paper also tests the different effects of binary and single stars on CMD studies. It is shown that binaries can better fit the observational CMDs of the sample globular clusters compared to single stars. This suggests that the effects of binary evolution should be considered when modeling the CMDs and stellar populations of star clusters and galaxies.

关键词： (Galaxy:) globular clusters: general -- galaxies: star clusters

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Effects of combined antibiotics on nitrification, bacteria and antibiotic resistance genes in activated sludge: Insights from legacy effect of antibiotics

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Journal of Environmental Sciences 2023年第9期131卷 96-110页

作者： Zhong-xing Zhang xiao-yan Fan xing Li Yu-xi Gao Jun-ru Zhao Faculty of Architecture Civil and Transportation EngineeringBeijing University of TechnologyBeijing 100124China

The effect of combined antibiotics exposure on nitrogen removal,microbial community assembly and proliferation of antibiotics resistance genes(ARGs)is a hotspot in activated sludge ***,it is unclear that how the historical antibiotic stress affects the subsequent responses of microbes and ARGs to combined *** this study,the effects of combined sulfamethoxazole(SMX)and trimethoprim(TMP)pollution on activated sludge under legacy of SMX or TMP stress with different doses(0.005-30 mg/L)were investigated to clarify antibiotic legacy *** activity was inhibited under higher level of combined exposure but a high total nitrogen removal(∼70%)*** on the full-scale classification,the legacy effect of past antibiotic stress had a marked effect on community composition of conditionally abundant taxa(CAT)and conditionally rare or abundant taxa(CRAT).Rare taxa(RT)were the keystone taxa in the microbial network,and the responses of hub genera were also affected by the legacy of antibiotic *** bacteria and genes were inhibited by the antibiotics and aerobic denitrifying bacteria(Pseudomonas,Thaurea and Hydrogenophaga)were enriched under legacy of high dose,as were the key denitrifying genes(napA,nirK and norB).Furthermore,the occurrences and co-selection relationship of 94 ARGs were affected by legacy ***,some shared hosts(eg.,Citrobacter)and hub ARGs(eg.,mdtD,mdtE and acrD)were ***,antibiotic legacy could affect responses of activated sludge to combined antibiotic and the legacy effect was stronger at higher exposure levels.

关键词： Antibiotics Antibiotic resistance genes(ARGs) Combined pollution Full-scale classification Legacy effect

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Entanglement of Two-Qubit Quantum Heisenberg XYZ Chain

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Chinese Physics Letters 2002年第8期19卷 1044-1047页

作者： xi xiao-Qiang, Hao San-ru Institute of Modern Physics Northwest University Fundamental Department Xi"an Institute of Posts and Telecommunications

We derive the analytic expression of the concurrence in the quantum Heisenberg XYZ model and discuss the influence of parameters J, Δ and Γ on the concurrence. By choosing different values of Γ and Δ, we obtain the XX, XY, XXX and XXZ chains. The concurrence decreases with increasing temperature. When T→0, the concurrence reaches its maximum value 1, i.e. the entangled state, |Ψ> = (((2)^1/2)/2)(|01>-|10>), is maximum entanglement. For the XXZ chain, when , the concurrence will meet its maximum value Cmax = (sinh (1/T))/(cosh (1/T)).

关键词： Chains

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