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An epidermal sEMG tattoo-like patch as a new human–machine interface for patients with loss of voice

Microsystems & Nanoengineering 2020年第1期6卷 1209-1221页

作者： Huicong Liu Wei Dong Yunfei Li Fanqi Li Jiangjun Geng Minglu Zhu Tao Chen Hongmiao Zhang Lining Sun Chengkuo lee School of Mechanical and Electric Engineering Jiangsu Provincial Key Laboratory of Advanced RoboticsSoochow University215123 SuzhouChina Department of Electrical&Computer Engineering National University of Singapore4 Engineering Drive 3Singapore 117576Singapore National University of Singapore Suzhou Research Institute(NUSRI) Suzhou Industrial Park215123 SuzhouChina

Throat cancer treatment involves surgical removal of the tumor,leaving patients with facial disfigurement as well as temporary or permanent loss of *** electromyography(sEMG)generated from the jaw contains lots of voice ***,it is difficult to record because of not only the weakness of the signals but also the steep skin *** paper demonstrates the design of an imperceptible,flexible epidermal sEMG tattoo-like patch with the thickness of less than 10μm and peeling strength of larger than 1N cm−1 that exhibits large adhesiveness to complex biological surfaces and is thus capable of sEMG recording for silent speech *** a tester speaks silently,the patch shows excellent performance in recording the sEMG signals from three muscle channels and recognizing those frequently used instructions with high accuracy by using the wavelet decomposition and pattern *** average accuracy of action instructions can reach up to 89.04%,and the average accuracy of emotion instructions is as high as 92.33%.To demonstrate the functionality of tattoo-like patches as a new human–machine interface(HMI)for patients with loss of voice,the intelligent silent speech recognition,voice synthesis,and virtual interaction have been implemented,which are of great importance in helping these patients communicate with people and make life more enjoyable.

关键词： sEMG patients patch

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Feature identification in complex fluid flows by convolutional neural networks

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Theoretical & Applied Mechanics Letters 2023年第6期13卷 447-454页

作者： Shizheng Wen Michael W.lee Kai M.Kruger Bastos Ian K.Eldridge-Allegra Earl H.Dowell Department of Mathematics ETH ZurichZürich 8092Switzerland NASA Langley Research Center HamptonVA 23666USA Rivian San FranciscoCA 94080USA Department of Mechanical Engineering and Materials Science Duke UniversityDurhamNC 27708USA

Recent advancements have established machine learning's utility in predicting nonlinear fluid dynamics,with predictive accuracy being a central motivation for employing neural ***,the pattern recognition central to the networks function is equally valuable for enhancing our dynamical insight into the complex fluid *** this paper,a single-layer convolutional neural network(CNN)was trained to recognize three qualitatively different subsonic buffet flows(periodic,quasi-periodic and chaotic)over a high-incidence airfoil,and a near-perfect accuracy was obtained with only a small training *** convolutional kernels and corresponding feature maps,developed by the model with no temporal information provided,identified large-scale coherent structures in agreement with those known to be associated with buffet *** to hyperparameters including network architecture and convolutional kernel size was also *** coherent structures identified by these models enhance our dynamical understanding of subsonic buffet over high-incidence airfoils over a wide range of Reynolds numbers.

关键词： Subsonic buffet flows Feature identification Convolutional neural network Long-short term memory

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A systematic correlation between morphology of porous carbon cathode and electrolyte in lithium-sulfur battery

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Journal of Energy Chemistry 2021年第10期30卷 561-573,I0014页

作者： Jihyeon Park Seoyoung Yoon Seoyeah Oh Jiyoon Kim Dongjun Kim Geonho Kim Jiyeon lee Myeong Jun Song Ilto Kim Kwonnam Sohn Jiwon Kim School of Integrated Technology College of EngineeringYonsei University85 Songdogwahak-roYeonsu-guIncheon 21983Republic of Korea Integrated Science and Engineering Division Underwood International CollegeYonsei University85 Songdogwahak-roYeonsu-guIncheon 21983Republic of Korea Integrated Biotechnology and Translational Medicine Graduate SchoolYonsei University85 Songdogwahak-roYeonsu-guIncheon 21983Republic of Korea LG Chem. LG Science Park30 Magokjungang 10-roGangseo-guSeoul 07796Republic of Korea

Porous carbon has been applied for lithium-sulfur battery cathodes,and carbonized metal-organic framework(MOF)is advantageous in tuning the ***,we have systematically synthesized water-distorted MOF(WDM)derived porous carbon via controlling the proportion of both water in a mixed solvent(dimethylformamide and water)and ligand in MOF-5 precursors(metal and ligand),which is categorized by its morphology(*** stone(closed),Tassel(open)and Intermediate(semi-open)).For example,decrease in water and increase in ligand content induce Cracked stone WDMs which showed the highest specific surface area(2742-2990 m^(2)/g)and pore volume(2.81-3.28 cm^(3)/g)after *** effect of carbonized WDMs(CWDMs)on battery performance was examined by introducing electrolytes with different sulfur reduction mechanisms(***/DME and ACN_(2) LiTFSITTE):Closed framework effectively confines polysulfide,whereas open framework enhances electrolyte *** initial capacities of the batteries were in the following order:Cracked stone>Intermediate>Tassel for DOL/DME and Intermediate>Tassel>Cracked stone for ACN_(2) *** note,Intermediate CWDM exhibited the highest initial capacity and retained capacity after 100 cycles(1398 and 747 mAh/g)in ACN_(2) LiTFSI-TTE electrolyte having advantages from both open and closed *** sum,we could correlate cathode morphology(openness and pore structure)and electrolyte type(*** solubility)with lithium-sulfur battery performance.

关键词： Lithium-sulfur battery Metal-organic framework Hierarchical porous carbon cathode Morphology control Electrolyte Lithium polysulfide solubility

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A computational study of the chemokine receptor CXCR1 bound with interleukin-8

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Chinese Physics B 2018年第3期27卷 534-543页

作者： Yang Wang Cecylia Severin Lupala Ting Wang Xuanxuan Li Ji-Hye Yun Jae-hyun Park Zeyu Jin Weontae lee Leihan Tan Haiguang Liu Complex Systems Division Beijing Computational Science Research Center Beijing 100193 China Genome Center University of California Davis 451 East Health Science Drive Davis CA 95616 USA Department of Engineering physics Tsinghua University Beijing 100086 China Department of Biochemistry College of Life Science ＆ Biotechnology Yonsei University Seou103722 South Korea Department of Physics and Institute of Computational and Theoretical Studies Hong Kong Baptist University Hong Kong China

CXCR1 is a G-protein coupled receptor, transducing signals from chemokines, in particular the interleukin-8 （1L8） molecules. This study combines homology modeling and molecular dynamics simulation methods to study the structure of CXCRI-IL8 complex. By using CXCR4-vMIP-II crystallography structure as the homologous template, CXCRI-IL8 complex structure was constructed, and then refined using all-atom molecular dynamics simulations. Through extensive simulations, CXCRI-IL8 binding poses were investigated in detail. Furthermore, the role of the N-terminal of CXCR1 receptor was studied by comparing four complex models differing in the N-terminal sequences. The results indicate that the receptor N-terminal affects the binding of IL8 significantly. With a shorter N-terminal domain, the binding of IL8 to CXCR1 becomes unstable. The homology modeling and simulations also reveal the key receptor-ligand residues involved in the electrostatic interactions known to be vital for complex formation.

关键词： CXCRI-IL8 complex homology modeling ligand binding molecular dynamics

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Stereotactic body radiotherapy for isolated paraaortic lymph node recurrence from colorectal cancer

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World Journal of Gastroenterology 2009年第48期15卷 6091-6095页

作者： Mi-Sook Kim Chul Koo Cho Kwang Mo Yang Dong Han lee Sun Mi Moon Young Joo Shin Department of RadiationOncology and Surgery Korea Institute of Radiological & Medical Sciences

AIM： To evaluate the efficacy and complications of stereotactic body radiotherapy in localized paraaortic lymph node recurrence from colorectal cancer. METHODS： From 2003 to 2009, 7 patients with paraaortic lymph node recurrence （1-3 lesions） from colorectal cancer were treated with stereotactic body radiotherapy. Total gross tumor volumes ranged from 4 to 40 mL. The doses were escalated from 36 Gy/patient to 51 Gy/patient and were delivered in 3 fractions. RESULTS： One and 3 year overall survival rates were 100% and 71.4%, respectively, and median survival was 37 mo. Grade IV intestinal obstruction was reported in 1 of 7 patients. This patient received 48 Gy in 3 fractions with a maximum point dose to the intestine of 53 Gy and V45Gy = 3.6 mL. However, 6 patients received an intestinal maximum point dose of 〈 51 Gy and V45Gy of 〈 1 mL, and did not develop any severe complications. CONCLUSION： This pilot study suggests selected paraaortic lymph node recurrence （1-3 closed lesions） that failed to respond to chemotherapy can be potentially salvaged by stereotactic body radiotherapy.

关键词： Stereotactic body radiotherapy Paraaortic lymph node recurrence Colorectal cancer

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Partial Fraction Decomposition by Repeated Synthetic Division

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American Journal of Computational Mathematics 2016年第2期6卷 153-158页

作者： Youngsoo Kim Byunghoon lee Department of Mathematics Tuskegee University Tuskegee AL USA

We present an efficient and elementary method to find the partial fraction decomposition of a rational function when the denominator is a product of two highly powered linear factors.

关键词： Partial Fraction Decomposition Synthetic Division Heaviside Coverup

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“One stone,two birds”solvent system to fabricate microcrystalline cellulose–Ti_(3)C_(2)T_(x)nanocomposite film as a flexible dielectric and thermally conductive material

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Nano Research 2023年第2期16卷 3240-3253页

作者： Yong-Zhu Yan Shuwei Li Sung Soo Park Wei-Jin Zhang Jun Seok lee Jung Rae Kim Dong Gi Seong Chang-Sik Ha Department of Polymer Science and Engineering School of Chemical EngineeringPusan National UniversityBusan 46241Republic of Korea School of Chemical and Biomolecular Engineering Pusan National UniversityBusan 46241Republic of Korea Division of Advanced Materials Engineering Dong-Eui UniversityBusan 47340Republic of Korea

A strategy for fabricating microcrystalline cellulose–Ti_(3)C_(2)T_(x)(MCC–MXene)nanocomposite films with high relative permittivity,high thermal conductivity,and excellent mechanical properties was *** MCC–MXene nanocomposite film was fabricated by casting a solution containing N,N-dimethylacetamide/lithium chloride(DMAc/LiCl)-soluble MCC and DMAcdispersible MXene nanosheets,followed by humidity control *** MXene nanosheets greatly enhanced the permittivity of the nanocomposite films owing to interfacial ***,the nanocomposite film with 20 wt.%MXene content achieved a desirable permittivity of 71.4 at 102 Hz(a 770%improvement against that of neat cellulose),while the dielectric loss only increased by 1.8 times(from 0.39 to 0.70).The obtained nanocomposite films with 20 wt.%and 30 wt.%MXene exhibited remarkable in-plane thermal conductivities of 8.523 and 9.668 W∙m^(−1)∙K^(−1),respectively,owing to the uniform dispersion and selfalignment of the MXene layered ***,the uniformly dispersed MXene nanosheets in the MCC network with interfacial interaction(hydrogen bonding)and mechanical entanglement endowed the nanocomposite films with excellent mechanical properties and ***,the thermal stability,water resistance,and antibacterial properties of the nanocomposite films were effectively improved with the introduction of ***,using DMAc/LiCl as the solvent system not only improves the compatibility between MCC and MXene but also avoids the problem of easy oxidation of MXene in aqueous *** the high stability of the MCC–MXene solution and enhanced properties of the MCC–MXene films,the proposed strategy manifests great potential for fabricating natural biomass-based dielectric materials.

关键词： Ti_(3)C_(2)T_(x) microcrystalline cellulose flexible dielectric thermally conductive N,N-dimethylacetamide/lithium chloride(DMAc/LiCl) compatibility

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Radial Pulse and Electrocardiography Modulation by Mild Thermal Stresses Applied to Feet: An Exploratory Study with Randomized, Crossover Design

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Chinese Journal of Integrative Medicine 2020年第4期26卷 299-306页

作者： Jang-Han Bae Boncho Ku Young Ju Jeon Hyunho Kim Jihye Kim Haebeom lee Jong Yeol Kim Jaeuk U.Kim Korea n Medici ne Fun dame ntal Research Divisi on Korea Institute of Oriental MedicineDaejeon(34054)Republic of Korea Department of Biofunctional Medicine and Diagnostics College of Korea n MedicineKyung Hee UniversitySeoul(02453)Republic of Korea Department of Human Informatics of Korean Medicine Interdisciplinary ProgramsKyung Hee UniversitySeoul(02453)Republic of Korea

Objective:To investigate the changes in radial pulse induced by thermal stresses(TSs).Methods:Sixty subjects were *** an open-label,2x2 crossover randomization design,both feet of each subject were immersed in 15%:water for cold stress(CS)and in 40 X:water for heat stress(HS)for 5 min *** pulse,respiration and electrocardiogram(ECG)signals were recorded before,during and immediately after the ***:The an alysis of heart rate variability revealed that CS in creased the low-freque ncy(LF)and high-frequency(HF)components(P<0.05)and that HS reduced the LF and HF components(P<0.01).Both TSs reduced the normalized LF,increased the normalized HF,and reduced the LF/HF *** differences in the ECG signals were more dominant during the TS sessions,but those in the radial pulse signals became more domi nant immediately after the TS sessi *** decreased the pulse depth(P<0.01)and in creased the radial augme ntation in dex(P<0.1),and HS in creased the pulse pressure(P<0.1)and sube ndocardial viability ratio(P<0.01).There were no significant differences in pulse rate during the three time sequences of each *** respiration rate was increased(P<0.1),and the pulse rate per respiration(P/R ratio)was significantly decreased(P<0.05)with *** HF region(10-30 Hz)of the pulse spectral density was suppressed during both ***:CS induced vasoconstriction and sympathetic reactions,and HS induced vasodilation and parasympathetic reacti *** on defi nitions used in pulse diag no sis,we made the novel discoveries that the pulse became slower(decreased P/R ratio),more floating and tenser under CS and that the HF region of the spectral power decreased significantly under both TSs.

关键词： radial pulse pulse diag no sis thermal stress electrocardiography heart rate variability

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Changes in peak inspiratory flow rate and peak airway pressure with endotracheal tube size during chest compression

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World Journal of Emergency Medicine 2020年第2期11卷 97-101页

作者： Jung Wan Kim Jin Woong lee Seung Ryu Jung Soo Park InSool Yoo Yong Chul Cho Hong Joon Ahn Department of Emergency Medicine Chungnam National University HospitalJung-guDaejeonRepublic of Korea Department of Emergency Medicine College of MedicineChungnam National UniversityJung-guDaejeonRepublic of Korea

BACKGROUND:Adequate airway management plays an important role in high-quality cardiopulmonary resuscitation(CPR).Airway management is usually performed using an endotracheal tube(ETT)during ***,no study has assessed the effect of ETT size on the fl ow rate and airway pressure during ***:We measured changes in peak inspiratory fl ow rate(PIFR),peak airway pressure(Ppeak),and mean airway pressure(Pmean)according to changes in ETT size(internal diameter 6.0,7.0,and 8.0 mm)and with or without CPR.A tidal volume of 500 mL was supplied at a rate of 10 times per minute using a mechanical *** compressions were maintained at a constant compression depth and speed using a mechanical chest compression device(LUCAS2,mode:active continuous,chest compression rate:102±2/minute,chest compression depth 2–2.5 inches).RESULTS:The median of several respiratory physiological parameters during CPR was significantly different according to the diameter of each ETT(6.0 vs.8.0 mm):PIFR(32.1 L/min[30.5–35.3]vs.28.9 L/min[27.5–30.8],P<0.001),Ppeak(48.84 cmH2O[27.46–52.11]vs.27.45 cmH2O[22.53–52.57],P<0.001),and Pmean(18.34 cmH2O[14.61–21.66]vs.13.66 cmH2O[8.41–19.24],P<0.001).CONCLUSION:The changes in PIFR,Ppeak,and Pmean were related to the internal diameter of ETT,and these values tended to decrease with an increase in ETT *** airway pressures were measured in the CPR group than in the no CPR group.

关键词： Cardiopulmonary resuscitation Intratracheal intubation Airway pressure

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Investigation of prodromal features in metabolic syndrome based on transcriptome analysis

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Genes & Diseases 2023年第3期10卷 708-711页

作者： Sang-Min Park Musun Park Hyo-Jeong Ban Su-Jin Baek Soo Yeon Kim Siwoo lee Hee-Jeong Jin Korean Medicine(KM)Data Division Korea Institute of Oriental MedicineDaejeon 34054Republic of Korea College of Pharmacy Chungnam National UniversityDaejeon 34134Republic of Korea

Metabolic syndrome(MetS)is a complex condition that significantly increases the risk of several diseases,including heart disease and *** with MetS show both pro-inflammatory and pro-thrombotic states;however,the state... 详细信息

关键词： diseases Metabolic Patients

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