检索结果-南通市图书馆

维普期刊数据库

Efficient implementation of quantum permutation algorithm using a polar SrO molecule in pendular states

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2025年第2期77卷 41-53页

作者： Jie-ru hu Zuo-Yuan Zhang Jin-Ming Liu State Key Laboratory of Precision Spectroscopy School of Physics and Electronic Science East China Normal University School of Physical Science and Technology Yangzhou University Chongqing Key Laboratory of Precision Optics Chongqing Institute of East China Normal University

Quantum algorithms offer more enhanced computational efficiency in comparison to their classical counterparts when solving specific tasks. In this study, we implement the quantum permutation algorithm utilizing a polar molecule within an external electric field. The selection of the molecular qutrit involves the utilization of field-dressed states generated through the pendular modes of SrO. Through the application of multi-target optimal control theory, we strategically design microwave pulses to execute logical operations, including Fourier transform,oracle Ufoperation, and inverse Fourier transform within a three-level molecular qutrit *** observed high fidelity of our outcomes is intricately linked to the concept of the quantum speed limit, which quantifies the maximum speed of quantum state manipulation. Subsequently,we design the optimized pulse sequence to successfully simulate the quantum permutation algorithm on a single SrO molecule, achieving remarkable fidelity. Consequently, a quantum circuit comprising a single qutrit suffices to determine permutation parity with just a single function evaluation. Therefore, our results indicate that the optimal control theory can be well applied to the quantum computation of polar molecular systems.

关键词： polar molecule optimal control quantum permutation algorithm pendular states

Tumor inflammation-specific self-amplifying fluorescent molecular probes induce an anti-tumor immune response

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2025年第1期68卷 273-287页

作者： Shuguang Yang Lijun hu hong Xiao Zecong Xiao Xintao Shuai PCFM Lab of Ministry of Education School of Materials Science and EngineeringSun Yat-sen UniversityGuangzhou 510275China Nanomedicine Research Center The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630China Department of Medical Ultrasound The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630China Department of Ultrasound The Fifth Affiliated HospitalSun Yat-sen UniversityZhuhai 519000China

Enhancing the concentration of exogenous molecular drugs within the tumor microenvironment through enzyme-catalyzed polymerization presents a novel strategy for cancer ***,the optimization of the catalytic efficiency is often impeded by the inefficient expression of ***,we reported a self-amplifying fluorescent molecular probe,Bis-HTPICG,for photodynamic therapy(PDT)and subsequent PDT-induced *** Bis-HTP-ICG probe possesses a noticeable enzyme-catalyzed polymerization facilitated by myeloperoxidase(MPO),a crucial enzyme secreted by neutrophils at inflammation *** exposure to laser irradiation,Bis-HTP-ICG showed a high PDT efficacy,inducing an acute inflammatory response that stimulates further recruitment of neutrophils and then elevated MPO *** heightened level of MPO enhances the accumulation of the Bis-HTP-ICG via self-polymerization or binding with intratumoral proteins following MPO enzyme catalysis,instigating a self-amplifying chain reaction cycle involving Bis-HTP-ICG,neutrophils and ***,PDT efficiently incites immunogenic cell death(ICD)in tumor cells,initiating an anti-tumor immune response including dendritic cells(DCs)maturation,T cell proliferation and reprogramming of tumor-associated neutrophils(TANs).This work portrays a promising strategy for self-amplification of fluorescent molecular probes through adjustable enzyme levels,potentially offering a unique avenue to enhance the tumor accumulation of molecular drugs for improved tumor therapy.

关键词： fluorescent molecular probes self-amplifying myeloperoxidase photodynamic therapy

维普期刊数据库

Catalytic production of high-energy-density spiro polycyclic jet fuel with biomass derivatives

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第2期101卷 760-768页

作者： Wen-Jing Zhang Yan-Cheng hu Yan-hong Tan Jia Li Ning Li Jing-Pei Cao School of Chemical Engineering and Technology China University of Mining and Technology CAS Key Laboratory of Science and Technology on Applied Catalysis Dalian Institute of Chemical Physics Chinese Academy of Sciences

High-energy-density（HED） fuel（*** used JP-10 and RJ-4）,featuring compact 3D polycyclic structure with high strain,is of critical importance for volume-limited military aircraft,since their high density and combustion heat can provide more propulsion *** reduce the reliance on petroleum source,it is highly desirable to develop renewable alternatives for the production of strained polycyclic HED fuel,but which remains a big challenge because of the inaccessibility caused by the high strain,We herein demonstrate a three-step catalytic route towards highly strained C17and C18spirofuel with biomass *** process includes catalytic aldol condensation of renewable cyclohexanone/cyclopentanone with benzaldehyde,catalytic spiro Diels-Alder（D-A） reaction of aldol adduct with isoprene,and catalytic *** key spiro D-A reaction is enabled by the catalysis of heterogeneous Lewis acidic ionic *** chloroaluminate IL,formed by benign urea and AICl3,exhibits good catalytic performance and reusability for this *** eventual hydrodeoxygenation（HDO）over Pd/C and H-Y produces strained tricyclic spirofuel with density>0.93 g/mL,combustion heat>41 MJ/L and freezing point <-40℃,which are better than the properties of tactical fuel ***,it is anticipated that the as-prepared renewable fuels have the potential to replace traditional petroleum-derived HED fuels.

关键词： Biomass derivatives Cycloaddition High-energy-density Lewis acidic ionic liquid Spiro polycyclic fuel

Stable partial nitrification was achieved for nitrogen removal from municipal wastewater by gel immobilization:A pilot-scale study

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2025年第5期151卷 529-539页

作者： Xin hu hong Yang Xiaoyue Fang Xuyan Liu Jiawei Wang Xiaotong Wang Yongsheng Bai Bojun Su Key Laboratory of Beijing for Water Quality Science and Water Environmental Recovery Engineering Faculty of ArchitectureCivil and Transportation EngineeringBeijing University of TechnologyBeijing 100124China Beijing General Municipal Engineering Design&Research Institute Co. Ltd.Beijing 100044China Hebei GEO University Shijiazhuang 050031China Hebei Key Laboratory of Water Quality Engineering and Comprehensive Utilization of Water Resources Hebei University of ArchitectureZhangjiakou 075000China School of Environmental Science and Safety Engineering Tianjin University of TechnologyTianjin 300384China Beijing Drainage Group Co.Ltd. Beijing 100022China

As an energy and carbon saving process for nitrogen removal from wastewater,the partial nitrification and denitrification process(PN/D)has been extensively ***,achieving stable PNinmunicipalwastewater has always been *** this study,a gel immobilized PN/D nitrogen removal process(GI-PN/D)was established.A 94 days pilot-scale experiment was conducted using real municipal wastewater with an ammonia concentration of 43.5±5.3mg N/L at a temperature range of 11.3–28.7◦*** nitrogen removal performance and associated pathways,shifts in the microbial community as well as sludge yield were *** results were as follows:the effluent TN and COD were 0.6±0.4mg/L and 31.1±3.8 mg/L respectively,and the NAR exceeding 95%.GI-PN/D achieved deep nitrogen removal ofmunicipalwastewater through stable PN without taking any *** primary pathways for nitrogen removal were identified as denitrification,simultaneous nitrification-denitrification,and aerobic ***-throughput sequencing analysis revealed that the immobilized fillers facilitated the autonomous enrichment of functional bacteria in each reactor,effectively promoting the dominance and stability of the microbial *** addition,GI-PN/D had the characteristic of low sludge yield,with an average sludge yield of 0.029 kg SS/kg *** study provides an effective technical for nitrogen removal from municipal wastewater through PN.

关键词： Gel immobilization Partial nitrification Deep nitrogen removal Autonomous enrichment Sludge yield

Boosting characteristic emissions of lanthanide in Cs_(2)Ag_(0.6)Na_(0.4)InCl_(6-x)Br_(x) double perovskites via mixing halide

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2025年第1期43卷 39-46,I0002页

作者： Shujian Wang Dejian Chen Jie hu Sisi Liang Kunyuan Xu Maochun hong Haomiao Zhu University of Science and Technology of China Hefei230026China Ganjiang Innovation Academy Chinese Academy of SciencesGanzhou341000China CAS Key Laboratory of Design and Assembly of Functional Nanostructures and Fujian Key Laboratory of Nanomaterials Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou350002China Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials Xiamen Research Center of Rare Earth MaterialsHaixi InstitutesChinese Academy of SciencesXiamen361021China

Lanthanide ions(Ln^(3+))doping provides a potential strategy to control over the luminescent properties of lead-free halide double perovskite nanocrystals(DP NCs).However,due to the low energy transfer efficiency between self-trapped exciton(STE)and Ln^(3+)ions,the characteristic emissions of Ln^(3+)ions are not ***,the energy transfer mechanism between STE and Ln^(3+)ions is also elusive and requires in-depth *** chose trace Bi^(3+)-doped Cs_(2)Ag_(0.6)Na_(0.4)InCl_(6-x)Br_(x) as a representative DP matrix to demonstrate that by tuning the bromide concentration,the Ln^(3+)emission can be greatly *** enhanced STE and Ln^(3+)ions energy transfer originates from the high covalency of Ln-Br bond,which contributes to improve ment of the characteristic emission of Ln^(3+)*** re,optical spectroscopy reveals that the energy transfer mechanism from DP to Eu^(3+)ions is different from all the other doped Ln^(3+)*** energy transfer from DP to Eu^(3+)ions is mostly through Eu-Br charge transfer while the other Ln^(3+)ions are excited by energy transfer from *** distinct energy transfer mechanism has resulted from the energy separation between the excited energy level of Ln^(3+)ions and the bottom of conduction band of *** increasing the energy separation,the energy transfer from STE to Ln^(3+)ions is less efficient because of the generation of a larger number of phonons and finally becomes impossible for Eu^(3+)*** results provide new insight into tuning the energy transfer of Ln^(3+)-doped DP NCs.

关键词： Double perovskitenanocrystal Lead free Lanthanideions Energytransfer Rare earths

维普期刊数据库

Improved oxygen electrocatalysis at Fe N4 and Co N4 sites via construction of axial coordination

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2025年第2期36卷 482-487页

作者： Ze Zhang Lei Yang Jin-ru Liu Hao hu Jian-Li Mi Chao Su Bei-Bei Xiao Zhi-Min Ao School of Energy and Power Engineering Jiangsu University of Science and Technology Institute for Computation in Molecular and Materials Science School of Chemistry and Chemical Engineering Nanjing University of Science and Technology Institute for Advanced Materials School of Materials Science and Engineering Jiangsu University Advanced Interdisciplinary Institute of Environment and Ecology Beijing Normal University

The quest for efficient and durable catalysts using abundant resources has garnered significant interest in the field of bifunctional oxygen *** this contribution,we have designed a FeN4or CoN4embedded graphene-based bilayer as active layer and TMC3or TMN3doped graphene as supporting layer,named as FeN4/TMC3or FeN4/TMN3and CoN4/TMC3or CoN4/TMN3,wherein TM strands for transition *** on density functional theory calculations,our results demonstrate that the interaction formed between dual metal atoms in the bilayer interspace leads to the coordination environment altered from flat four-coordination to spatial five-coordination,further stabilizing the bilayer structure and impairing its affinity toward the O-containing *** to thermodynamic analysis,the bilayers of CoN4/CoN3,FeN4/FeC3,FeN4/CoC3,FeN4/NiC3,FeN4/ZnC3,FeN4/FeN3,FeN4/CrN3and FeN4/ZnN3are attractively promising for bifunctional oxygen electrocatalysis due to the small overpotential differenceΔη between oxygen reduction and oxygen evolution that are less than 1 *** functional theory calculations combined with machine learning analysis directly identify the key role played by the interbinding formed between bilayers,that boosts catalytic activity,which establishes a predictable framework for a fast screen for graphene-based bilayer vertical *** work opens up a new path for designing the efficient electrocatalysts via modification of coordination environment.

关键词： Density functional theory Machine learning Oxygen electrocatalysis Thermodynamic analysis

Dynamic partition of urban network considering congestion evolution based on random walk

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2025年第1期34卷 530-534页

作者： Zhen-Tong Feng Lele Zhang Yong-hong Wu Mao-Bin hu School of Engineering Science University of Science and Technology of ChinaHefei 230026China Department of Mathematics and Statistics University of MelbourneParkville VIC 3010Australia Department of Mathematics and Statistics Curtin UniversityPerth WA 6845Australia

The successful application of perimeter control of urban traffic system strongly depends on the macroscopic fundamental diagram of the targeted *** intensive studies on the partitioning of urban road networks,the dynamic partitioning of urban regions reflecting the propagation of congestion remains an open *** paper proposes to partition the network into homogeneous sub-regions based on random walk *** from selected random walkers,the road network is partitioned from the early morning when congestion emerges.A modified Akaike information criterion is defined to find the optimal number of *** boundary adjustment algorithms are adopted to optimize the partitioning results to further ensure the correlation of *** traffic data of Melbourne city are used to verify the effectiveness of the proposed partitioning method.

关键词： urban road networks dynamic partitioning random walk Akaike information criterion perimeter control

Health risks of rare earth elements exposure:Impact on mitochondrial DNA copy number and micronucleus frequency

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2025年第5期151卷 150-160页

作者： Shiyi hong Yali Zhang Qiaojian Zhang Zekang Su Guiping hu Li Wang Shanfa Yu Xiaojun Zhu Guang Jia Department of Occupational and Environmental Health Sciences School of Public HealthPeking UniversityBeijing 100083China School of Engineering Medicine and Beijing Advanced Innovation Center for Big Data-Based Precision Medicine Beihang UniversityBeijing 100083China Department of Toxicology School of Public HealthBaotou Medical CollegeBaotouInner Mongolia 014040China Henan Institute for Occupational Medicine Zhengzhou 450052China National Center for Occupational Safety and Health Beijing 102308China Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety School of Public HealthPeking UniversityBeijing 100083China

Toxic effects in terms of mitochondria and hereditary substances have been characterized in vitro for individual rare earth elements,while,the joint effects of mixed elements exposure in the population remain *** on the Occupational Chromate Exposure Dynamic Cohort of China,this study investigated the relationship between 15 blood rare earth elements(cerium,dysprosium,erbium,europium,gadolinium,holmium,lanthanum,lutetium,neodymium,praseodymium,samarium,terbium,thulium,yttrium,and ytterbium)and mitochondrial DNA copy number(MtDNACN)as well as peripheral blood lymphocyte micronucleus frequency(MNF).The elastic net was used to select elements highly correlated with effect indicators,whose dose-response relationships were further illustrated by restricted cubic *** kernel regressionwas employed to explore the combined effects of elements and the contributions of single *** results showed that most rare earth elementswere positively correlatedwith effect indicators,with yttrium showing the strongest association(β(95%CI):0.139(0.1089–0.189)for MtDNACN,0.937(0.345–1.684)for MNF).In the mixed exposure model,with the exposure level fixed at the 50th percentile as the reference,the effect estimates on MtDNACN and MNF increased by 0.228 and 0.598 units,respectively,at the 75th *** single effect analysis implied that yttrium,lanthanum and terbium contributed the most to the elevation of MtDNACN,while yttrium posed the highest risk for genetic damage,accordingly,we provided recommendations to prioritize these elements of *** addition,we observed a chief mediating effect of MtDNACN on the elevation of MNF caused by lanthanum,whereas further mechanistic exploration is required to confirm this finding.

关键词： Rare earth elements Mitochondrial DNA copy number Micronucleus frequency Mixed effect

Advanced pancreatic cancer treated with camrelizumab combined with apatinib:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2025年第2期17卷 284-290页

作者： Yun-Hao Luo Ting He Lu Lin Rong-Qiu Wang hong-Xia Cai Wen hu Department of Critical Care Medicine Chengdu First People's HospitalChengdu 610000Sichuan ProvinceChina Department of Radiology Sichuan Second Hospital of Traditional Chinese MedicineChengdu 610000Sichuan ProvinceChina Department of Oncology Chengdu Seventh People's HospitalChengdu 610000Sichuan ProvinceChina Department of Oncology West China Tianfu HospitalSichuan UniversityChengdu 610000Sichuan ProvinceChina

BACKGROUND The 5-year survival rate for patients with pancreatic cancer(PC)is 4%-12%.Surgery is the only treatment that offers curative potential,but only 15%-20%of patients are eligible for *** is prone to recurrence and metastasis,and the antitumor effect of chemotherapy is notably *** SUMMARY Histopathological analysis of a 53-year-old female PC patient who underwent Whipple surgery revealed poorly differentiated tumor cells infiltrating nerves,lymphatics,and blood *** patient received two different first-line chemotherapy regimens consecutively;however,both regimens struggled to control disease *** this period,the patient underwent liver metastasis ablation surgery,Candida albicans liver abscess,and stereotactic body *** the addition of camrelizumab to the modified FOLFIRINOX regimen,tumor control was *** patient subsequently refused to continue chemotherapy,and the antitumor regimen was changed to a combination of camrelizumab and *** patients received a combination of immunotherapy and targeted therapy,the length of hospital stay was significantly ***,all side effects were within acceptable limits,leading to an improved quality of life and prolonged progression-free ***,the pain associated with cancer,coupled with the side effects of opioid analgesics,has led the patient to reject all available anticancer treatment *** one month after camrelizumab and apatinib were discontinued without medical authorization,the PC recurred and rapidly progressed to widespread metastasis,ultimately leading to the patient's death approximately one month *** overall survival was 2 *** Immunotherapy and targeted therapy have the potential to increase both the quality of life and survival time of PC patients,particularly those whose tumor progression is not effectively controlled by chemotherapy ***,further clinical trials a

关键词： Advanced pancreatic cancer Immunotherapy Camrelizumab Targeted therapy Apatinib Case report