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世界核心医学期刊文摘（胃肠病学分册） 2005年第8期1卷 22-23页

作者： sherman K.E shire N.J rouster s.d 樊菁 department of Me dicine Division of Digestive Diseases Univ. of Cincinnati Coll. of Med. CincinnatiOH 45267 -0595 United States.Dr

Background &Aims: Kinetic modeling of hepatitis C virus(HCV) response to inte rferon (IFN)-bas.d therapy provides insights into factors associated with treat ment ***/human immunodeficiency virus (HIV)-co-infected patients show lower response rates vs. HCV-monoinfected patients. Reasons for this remain un clear. This study evaluated kinetic parameters and treatment responses in co-in fected vs monoinfected patients. Methods: Co-infected patients were randomized within a Us multicenter trial (ACTG 5071) to receive pegylated-interferon (PEG -IFN) alfa-2a +ribavirin *** alfa-2a +ribavirin. Monoinfected controls w ere matched prospectively for treatment, genotype, age, sex, race, and histology .Quantitative HCV-RNA testing was performed at hours 0,6, 12, 24, 48, and 72; d ays 7, 10, 14, 28, and 56; and weeks 12,24, 48, and 72. Results: Twelve HCV/HIV -co-infected and 15 HCV-monoinfected patients underwent viral kinetic samplin *** HIV-positive patients the mean Cd4+count was 325 cells/mm3. seventy-f ive percent of patients were genotype *** HCV-RNA level was undetectable at 7 2 weeks in 25%and 40%of co-infected and monoinfected patients, respectively.P hase 1/2 declines, free virus clearance rate, and infected hepatocyte death rate were not affected by co-infection status but differed by treatment. Efficiency (e) ≥90%at 60 hours was associated with viral clearance (P =. 02). Modeling w ith pooled parameters suggests baseline viral load is a key factor in time to re sponse in this cohort. Predicted clearance time increas.d by 28%in co-infected patients. Conclusions: Co-infection status.did not affect key kinetic paramete rs. Among kinetic parameters, efficiency was associated significantly with viral clearance. Co-infected patients may require longer treatment duration thanmono infected patients given their generally higher baseline viral loads.

关键词：丙型肝炎治疗应答感染状态单一感染合并感染者肝细胞死亡应答率清除率多中心试验研究评价

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利用EsTARFM模型获取南方红壤区高时空分辨率MOdIs遥感蒸散估算数据

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中国农业气象 2024年第9期45卷 953-967页

作者：冯静怡景元书冉楚钰 sachini Kaushalya dissanayake s.d 南京信息工程大学应用气象学院/气象灾害预报预警与评估协同创新中心/江苏省农业气象重点实验室南京210044

蒸散发是水分循环的重要环节,影响着作物生长和粮食生产,获得长时序高空间分辨率蒸散发过程数据有助于优化区域水资源配置。基于Landsat和MOdIs遥感数据,结合地面观测通量数据和气象数据,利用sEBs模型和EsTARFM模型获得了南方红壤区2019... 详细信息

蒸散发是水分循环的重要环节,影响着作物生长和粮食生产,获得长时序高空间分辨率蒸散发过程数据有助于优化区域水资源配置。基于Landsat和MOdIs遥感数据,结合地面观测通量数据和气象数据,利用sEBs模型和EsTARFM模型获得了南方红壤区2019年4−10月高时空分辨率日蒸散量,并分析高时空分辨率日蒸散量时空变化特征及其影响因素。结果表明:高空间分辨率的遥感影像可获得精度更高的遥感蒸散模拟效果,基于Landsat遥感数据驱动的sEBs模型的模拟效果优于基于MOdIs遥感数据作为输入的sEBs模型。EsTARFM模型获得的高时空分辨率日蒸散量与实测蒸散量对比,RMsE为0.68mm·d^(−1),R^(2)为0.87。模拟获得的2019年4−10月高时空分辨率日蒸散量在空间变化上与土地利用类型相关。各土地利用类型的蒸散量表现为林地>稻田>其他农用地,在时间变化上,4−8月蒸散量呈上升趋势,8−10月蒸散量则逐渐降低,气温是影响研究区域蒸散量的主要气象因子。基于sEBs模型和EsTARFM模型获得的高时空分辨率蒸散量与实测蒸散量具有良好的相关性,sEBs模型与EsTARFM模型结合的方法可作为估算南方红壤区蒸散量的有效工具。

关键词：蒸散发 sEBs EsTARFM 遥感时空融合技术

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Flexible ultra-thin super-resolution endoscopy

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science China(Physics,Mechanics & Astronomy) 2024年第3期67卷 171-172页

作者： George s.d.Gordon department of Electrical and Electronic Engineering University of NottinghamNottingham NG7 2RDUK

In recent years, multimode fiber(MMF) has become an important tool for high-resolution endoscopic imaging in narrow channels(e.g., in the brain via needles or ins.de blood vessels) due to its high mode density and fine diameter, typically stacle to widespread deployment in applications is that realistic perturbations, including bending, twisting and changes in temperature, cause unacceptable image degradation.

关键词： fiber resolution typically

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Generalized polynomial chaos expansion by reanalysis using static condensation bas.d on substructuring

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Applied Mathematics and Mechanics(English Edition) 2024年第5期45卷 819-836页

作者： d.LEE s.CHANG J.LEE department of Automotive Engineering Hanyang UniversitySeoul 04763Republic of Korea school of Mechanical Engineering Chungnam National UniversityDaejeon 34134Republic of Korea department of Mechanical Robotics and Energy EngineeringDongguk UniversitySeoul 04620Republic of Korea

This paper presents a new computational method for forward uncertainty quantification(UQ)analyses on large-scale structural systems in the presence of arbitrary and dependent random *** method consists of a generalized polynomial chaos expansion(GPCE)for statistical moment and reliability analyses associated with the stochastic output and a static reanalysis method to generate the input-output data *** the reanalysis,we employ substructuring for a structure to isolate its local regions that vary due to random *** allows for avoiding repeated computations of invariant substructures while generating the input-output data *** substructuring with static condensation further improves the computational efficiency of the reanalysis without losing ***,the GPCE with the static reanalysis method can achieve significant computational saving,thus mitigating the curse of dimensionality to some degree for UQ under high-dimensional *** numerical results obtained from a simple structure indicate that the propos.d method for UQ produces accurate solutions more efficiently than the GPCE using full finite element analyses(FEAs).We also demonstrate the efficiency and scalability of the propos.d method by executing UQ for a large-scale wing-box structure under ten-dimensional(all-dependent)random inputs.

关键词： forward uncertainty quantification(UQ) generalized polynomial chaos expansion(GPCE) static reanalysis method static condensation substructuring

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Ion heat transport in electron cyclotron resonance heated L-mode plasma on the T-10 tokamak

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Plasma science and Technology 2024年第4期26卷 52-60页

作者： V.A.KRUPIN M.R.NURGALIEV A.R.NEMETs I.A.ZEMTsOV s.d.sUNTsOV T.B.MYALTON d.s.sERGEEV N.A.sOLOVEV d.V.sARYCHEV d.V.RYJAKOV s.N.TUGARINOV N.N.NAUMENKO National Research Centre“Kurchatov Institute” Moscow 123182Russia Bauman Moscow state Technical University Moscow 105005Russia Institution“Project Center ITER” Moscow 123098Russia JsC“sOLAR” Minsk 220034Belarus

Anomalous ion heat transport is analyzed in the T-10 tokamak plasma heated with electron cyclotron resonance heating(ECRH) in second-harmonic extra-ordinary mode. Predictive modeling with empirical scaling for Ohmical heat conductivity shows that in ECRH plasmas the calculated ion temperature could be overestimated, so an increase of anomalous ion heat transport is required. To study this effect two scans are presented: over the EC resonance position and over the ECRH power. The EC resonance position varies from the high-field s.de to the low-field s.de by variation of the toroidal magnetic field. The scan over the heating power is presented with on-axis and mixed ECRH regimes. discharges with high anomalous ion heat transport are obtained in all cons.dered regimes. In these discharges the power balance ion heat conductivity exceeds the neoclassical level by up to 10 times. The high ion heat transport regimes are distinguished by three parameters: the ratio Te/Ti, the normalized electron density gradient R/■, and the ion–ion collisionality νii~*. The combination of high Te/Ti, high νii~*, and R/■=6-10 results in values of normalized anomalous ion heat fluxes up to 10 times higher than in the low transport scenario.

关键词： tokamak L-mode electron cyclotron resonance heating ion heat transport

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The magnetosheath at high spectral resolution

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Earth and Planetary Physics 2024年第1期8卷 234-246页

作者： K.d.Küntz d.Koutroumpa W.R.dunn A.Foster F.s.Porter d.G.sibeck B.Walsh The Henry A.Rowland department of Physics and Astronomy Johns Hopkins University3701 San Martin DriveBaltimoreMD21218USA NAsA Goddard space Flight Center 8800 Greenbelt RoadGreenbeltMD 20771USA LATMOs-OVsQ CNRSUVSQ Paris-SaclaySorbonne Université11 Boulevard d’Alembert78280GuyancourtFrance department of Physics and Astronomy University College LondonLondonUK The Centre for Planetary science at UCL/Birkbeck Gower StreetLondon WC1E 6BTUK Center for Astrophysics Harvard University&Smithsonian Institution60 Garden StreetCambridgeMA 02138USA Center for space Physics Boston University110 Cummington MallBostonMAUSA

While we eagerly anticipate sMILE’s(solar wind Magnetosphere Ionosphere Link Explorer)unprecedented X-ray observations of the Earth’s magnetosheath and the initiation of a new era of magnetospheric research,it seems appropriate to look ahead to the abilities of the next generation of astrophysics *** these,the Line Emission Mapper(LEM),a large aperture micro-calorimeter bas.d mission,is currently planned to be able to observe the magnetosheath at high spectral resolution(~2 eV).With a field of view of~30′,LEM will allow higher spatial resolution and higher cadence measurement of the motion of a very small portion of the magnetopause over relatively short periods of time(multiple hours),complementing sMILE’s global ***’s strength is its spectral *** will be able to measure the abundance of a broad range of elements and ionization states,many of which are inaccessible to current in situ instruments,and will be able to separate the emission from the magnetosheath from the emission from the cosmic X-ray background using the difference in their relative velocities.

关键词： magnetosheath charge exchange solar wind abundances

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The dorsal root ganglion as a target for neurorestoration in neuropathic pain

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Neural Regeneration Research 2024年第2期19卷 296-301页

作者： Guillermo Estivill-Torrús Ana Belen Martínez-Padilla Lourdes sánchez-salido Anne Baron-Van Evercooren Beatriz García-díaz Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina(IBIMA Plataforma BIONANd) MálagaSpain Unidad Clínica de Neurociencias Hospital Regional Universitario de MálagaMálagaSpain departamento de Biología Molecular y Bioquímica Universidad de MálagaSpain sorbonne Université Institut du Cerveau-Paris Brain Institute-ICMINSERMCNRSAP-HPHôpital Pitié-SalpêtrièreParisFrance

Neuropathic pain is a severe and chronic condition widely found in the general *** reason for this is the extensive variety of damage or diseases that can spark this unpleasant constant feeling in *** the processing of pain,the dorsal root ganglia constitute an important region where dorsal root ganglion neurons play a crucial role in the transmission and propagation of sensory electrical ***,the dorsal root ganglia have recently exhibited a regenerative capacity that should not be neglected in the understanding of the development and resolution of neuropathic pain and in the elucidation of innovative ***,we will review the complex interplay between cells(satellite glial cells and inflammatory cells)and factors(cytokines,neurotrophic factors and genetic factors)that takes place within the dorsal root ganglia and accounts for the generation of the aberrant excitation of primary sensory neurons occurring in neuropathic *** importantly,we will summarize an updated view of the current pharmacologic and nonpharmacologic therapies targeting the dorsal root ganglia for the treatment of neuropathic pain.

关键词： cytokines dorsal root ganglia genetic factors neuropathic pain neurotrophic factors pharmacologic and nonpharmacologic therapies satellite glial cells sensory neurons

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development and testing of a high-power s-band klystron at BINP sB RAs

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Nuclear science and Techniques 2024年第7期35卷 58-67页

作者： A.Levichev A.Barnyakov s.samoylov d.Nikiforov V.Ivanov M.Arsentyeva d.Chekmenev O.Pavlov I.Pivovarov Budker Institute of Nuclear Physics Lavrentyeva Av.11NovosibirskRussia630090 Novosibirsk state University Pirogova Str.2NovosibirskRussia630090

This paper details the development and testing of the first working prototype of the s-band high-power klystron,accomplished at the Budker Institute of Nuclear Physics,siberian Branch,Russian Academy of sciences(BINP sB RAs).Upon testing,the klystron demonstrated the following parameters:an operating frequency of 2856 MHz and a peak power output of 50 *** paper presents the klystron's.design,its constituent units,and pertinent processing procedures,along with discussions on the measurement of its parameters.

关键词： Klystron Linear accelerator Electron beam

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Assessing the biennial conference on science and technology(BICOsT IX)2023 technical output on renewable energy,energy storage,and green hydrogen in line with UN sdG commitments

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Clean Energy 2024年第2期8卷 85-88页

作者： s.K.B.d.silva K.G.d.Piyumali Rasitha Thilini suranjana Perera K.d.K.G.Kaluarachchi Thilini Munagamage R.M.R.Ahammed C.s.P.Piyankarage seyed shahmy Veranja Karunaratne National science and Technology Commission of sri Lanka ColomboSri Lanka sri Lanka Technological Campus(sLTC) PadukkaSri Lanka University of Peradeniya PeradeniyaSri Lanka

The development,production and utilization of renewable energy,energy storage and green hydrogen and the associated technologies in sri Lanka have great potential to contribute to the United Nations’sustainable development Goals(sdGs).The island aims to achieve 70%electricity generation from renewable energy sources by 2030(within the target of 40%utilization of renewable energy sources for the entire energy generation of the country by 2030).The power sector has to invest Us$11 billion from 2023 to 2030 to contribute to reaching this *** commentary aims to provide a critical perspective on the recommendations of the report from the National science and Technology Commission’s 9th biennial conference in 2023 on science and technology,the sub-thematic technical report on clean energy,energy storage and green hydrogen in line with the sdGs in the sri Lankan *** technical report provides insightful recommendations for sri Lanka’s energy sector under three main sections:renewable energy,energy storage and green ***,it explores the potential of various renewable energy sources,energy storage systems and green hydrogen as sustainable solutions to address the country’s energy challenges while emphasizing the spillover effects of them,which could contribute to the enterprise’s job creation and uplift the economy.

关键词： renewable energy energy storage green hydrogen sustainable development goals sri Lanka social economic environmental sustainable affordable

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structural,morphological,optical and antibacterial performances of rare earth(sm)-doped ZnO nanorods

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Journal of Rare Earths 2024年第11期42卷 2119-2127页

作者： A.Ravi J.samuel s.sahaya Jude dhas s.Usharani Turibius simon d.senthil Kumar s.K.Jasmin Vijitha A.sivakumar Raju suresh Kumar C.s.Biju department of Physics University College of Engineering department of Physics and Research Centre Malankara Catholic College Manonmaniam sundaranar University saveetha school of Engineering Saveetha Institute of Medical and Technical SciencesSaveetha University department of Chemistry S.I.V.E.T College department of Biotechnology Vivekanandha College of Arts and Science for Woman (Autonomous) department of Physics Vel Tech Rangarajan Dr.Sagunthala R & D Institute of Science and Technology department of Physics & Research Centre Muslim Arts College Key Laboratory of High-temperature and High-pressure study of the Earth's Interior Institute of GeochemistryChinese Academy of Sciences department of Chemistry College of ScienceKing Saud University department of Physics St. Alphonsa College of Arts and Science

The significant rise of ultra-violet（UV） radiation and pathogenic infectious bacteria poses a serious threat to global *** researchers' interests are attracted by novel materials with strong UVblocking ability,antibacterial activity and low toxicity to other *** this case,a simple wet chemical method with different annealing temperatures（400,500,and 600℃） was employed to create highly effective rare earth（sm）-doped ZnO ***（101） plane of wurtzite ZnO shifts towards a lower angle with increasing annealing temperature,according to the X-ray diffraction（XRd） study findings,which additionally establishes the consequence of lattice *** of doublet peaks of sm 3d(sm 3d5/2and sm 3d3/2) in the X-ray photoelectron spectroscopy（XPs） spectrum clearly validates the substitution of sm3+ions in the 500℃-annealed *** 500℃-annealed nanorods exhibit combined performances of the wide band gap,improved UV absorbance,and vivid green luminescent emission（563 nm）.Additio nally,the nanorods have favorable UV-blocking execution of 96% for UVA at 360 nm,92% for UVB at 320 nm,and 57% for UVC at 225 nm,which is greater than the majority of ZnO-related materials that have been reported up to this *** doping is also appropriate for improving bacterial inhibition against the two studied strains（Escherichia coli and staphylococcus aureus）,in addition to the intriguing features.discuss.d ***,with maximum inhibition zone diameters of 20±0.72 and 18±0.57 mm,respectively,these nanorods exhibit high inhibitory action against *** and *** bacterial *** rare earth-doped material developed during the current experiment,which was annealed at 500℃,could potentially serve as an effective replacement for UV-blocking and antibacterial material,especially for biomedical applications.

关键词： Wet chemical method rare earth doping Metal oxide UV-shielding Bacterial inhibition

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