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Response to discussion of‘Nutritional epidemiology methods and related statistical challenges and opportunities’

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Statistical Theory and Related Fields 2018年第1期2卷 23-26页

作者： ross l.prentice Ying Huang Fred Hutchinson Cancer Research Center and University of Washington Seattle WAUSA

We very much appreciate each of the three sets of comments on our *** manuscript argued thatthe nutritional epidemiology research area,which is soimportant to worldwide public health,is burdened withchallenges in estimating dietary intakes,both shortterm intakes and intakes over the years or decades thatmay be relevant to chronic disease *** nutritional epidemiology literature having chronic diseaseoutcomes mostly relies on dietary self-report *** few dietary variables having an established objective measure(biomarker),comparison with self-reportdata suggests that the data include not only a large‘noise’component,which available statistical methods can typically accommodate,but frequently also alarge systematic bias component that,for example,maydepend on such study subject body mass index(BMI),age and ethnicity,among other *** is the needto address this systematic bias component of dietaryintake assessment that stimulates our call for additionalreliance on biomarkers,for additional biomarker development,and for the development of novel and flexible statistical methods for use in disease associationanalyses.

关键词： intake epidemiology mostly

The Effect of Retinoic Acid on Neutrophil Innate Immune Interactions With Cutaneous Bacterial Pathogens

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Infectious Microbes & Diseases 2024年第2期6卷 65-73页

作者： Alexandra Stream ross Corriden Simon Döhrmann Richard l.Gallo Victor Nizet Ericka l.Anderson Division of Host-Microbe Systems and Therapeutics Department of PediatricsUniversity of California San Diego School of MedicineLa JollaCaliforniaUSA Department of Dermatology University of California San Diego School of MedicineLa JollaCaliforniaUSA Skaggs School of Pharmacy and Pharmaceutical Sciences University of California San DiegoLa JollaCaliforniaUSA

Vitamin A and its biologically active derivative,retinoic acid(RA),are important for many immune ***,in particular,is essential for the development of immune cells,including neutrophils,which serve as a front-line defense against *** vitamin A deficiency has been linked to higher susceptibility to infections,the precise role of vitamin A/RA in host-pathogen interactions remains poorly ***,we provided evidence that RA boosts neutrophil killing of methicillin-resistant Staphylococcus aureus(MRSA).RA treatment stimulated primary human neutrophils to produce reactive oxygen species,neutrophil extracellular traps and the antimicrobial peptide cathelicidin(ll-37).Because RA treatment was insufficient to reduce MRSA burden in an in vivo murine model of skin infection,we expanded our analysis to other infectious *** did not affect the growth of a number of common bacterial pathogens,including MRSA,Escherichia coli K1 and Pseudomonas aeruginosa;however,RA directly inhibited the growth of group A Streptococcus(GAS).This antimicrobial effect,likely in combination with RA-mediated neutrophil boosting,resulted in substantial GAS killing in neutrophil killing assays conducted in the presence of ***,in a murine model of GAS skin infection,topical RA treatment showed therapeutic potential by reducing both skin lesion size and bacterial *** findings suggest that RA may hold promise as a therapeutic agent against GAS and perhaps other clinically significant human pathogens.

关键词： retinoic acid neutrophil bacterial infection Staphylococcus aureus group A Streptococcus neutrophil extracellular traps antimicrobial peptide cathelicidin

Public health importance of light intensity physical activity

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Journal of Sport and Health Science 2024年第5期13卷 674-675页

作者： Robert ross Ian Janssen Mark S.Tremblay School of Kinesiology and Health Studies Queen’s UniversityKingstonON K7L 3N6Canada School of Medicine Division of Endocrinology and MetabolismQueen’s UniversityKingstonON K7L 3N6Canada Healthy Active living and Obesity Research Group Children’s Hospital of Eastern Ontario Research InstituteOttawaON K1H 8L1Canada Department of Pediatrics University of OttawaOttawaON K1H 8L1Canada

*** intensity physical activity(PA)benefits health PA guidelines worldwide recommend that adults accumulate 150 min of moderate intensity or 75 min of vigorous intensity PA(moderate-to-vigorous PA(MVPA))weekly to achieve health benefits.1-3 Absent from these guidelines are recommendations for light intensity PA(lPA,e.g.,walking at a leisurely pace of 3 km/h or less,equivalent to 1.5-2.9 metabolic equivalents).

关键词： intensity light benefits

limosilactobacillus mucosae FZJTZ26M3 prevents NAFlD in mice through modulation of lipid metabolism and gut microbiota dysbiosis

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Food Science and Human Wellness 2024年第3期13卷 1589-1601页

作者： Danting Dang Bowen li Mengfan Ding RPaul ross Catherine Stanton Jianxin Zhao Bo Yang Wei Chen State Key laboratory of Food Science and Resources Jiangnan UniversityWuxi 214122China School of Food Science and Technology Jiangnan UniversityWuxi 214122China International Joint Research Center for Probiotics&Gut Health Jiangnan UniversityWuxi 214122China APC Microbiome Ireland University College CorkCork T12 YT20Ireland Teagasc Food Research Centre MooreparkFermoyCork T12 YT20Ireland National Engineering Research Center for Functional Food Jiangnan UniversityWuxi 214122China

lactobacillus are considered promising therapeutic methods for nonalcoholic fatty liver disease(NAFlD).The effects of two strains of ltmosilactobacillus mucosae on NAFlD were investigated in this ***-old male C57Bl/6J mice were divided into 4 groups(n=8 per group,Control,Model,FZJTZ26M3,FGSYC17l3).*** FZJTZ26M3 reduced the mice 's body weight,liver weight,and adipose tissue weight after 12 weeks of *** to serum analysis,total cholesterol,triacylglycerol,and low-density lipoprotein cholesterol significantly decreased after *** FZJTZ26M3 *** pathology showed that *** FZJTZ26M3 was effective to ameliorate lipid deposition in NAFlD ***,the expression of the gene related to lipid metabolism in the liver and adipose tissue was analyzed,and the results indicated that *** FZJTZ26M3 could alleviate NAFlD by regulating lipid ***,the results of 16S rRNA gene sequencing revealed a drop in the relative abundance of Ruminococcaceae,which is linked to inflammation,but the relative abundance of a potential probiotic Akkermansia significantly increased after *** FZJTZ26M3 ***,*** FZJTZ26M3 could be a candidate to prevent NAFlD.

关键词： limosilactobacillus mucosae Nonalcoholic fatty liver disease(NAFlD) Probiotic lipid metabolism Gut microbiota

Determination of the standardized ileal digestible calcium requirement of ross broilers from hatch to day 14 post-hatch

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Animal Nutrition 2024年第1期16卷 122-129页

作者： Carrie l.Walk Raffaella Aureli Pauline Jenn DSM Nutritional Products Delves RoadHeanorDerbyshireDE757SGUnited Kingdom Research Center for Animal Nutrition and Health DSM Nutritional ProductsVillage-Neuf68128France

An experiment was conducted to determine the standardized ileal digestible(SID)calcium requirement of fast-growing broilers from hatch to d 14 *** 308(n=360)male broilers were obtained on day of hatch and allocated to 1 of 5 treatments in battery *** were 6 birds per cage and 12 pens per *** treatments were formulated to contain 0.60%,0.46%,0.32%or 0.18%SID *** final treatment was formulated using total Ca to meet or exceed all nutrient requirements,including 0.90%total Ca and 0.49%non-phytate P(nPP),using the same *** treatment was the reference diet for comparison and validation of the SID Ca *** and feed were weighed at placement and on d *** and ileal contents were obtained on d 14 and excreta was collected per pen and pooled on d *** were analyzed using JMP Pro and requirements were estimated using 3different non-linear regression *** the SID Ca content in the diet from 0.18%to 0.60%improved(quadratic,Plity corrected feed conversion ratio(mFCR).The estimated SID Ca requirement to optimize gain or m FCR was between 0.39%and 0.52%.Tibia ash percent and weight increased(quadratic,Plization was improved in birds fed diets formulated using SID Ca compared with birds fed the reference *** conclusion,the SID Ca requirement of fast-growing broilers from hatch to d 14 was estimated between 0.534%and 0.398%when quadratic,straight-broken line,or quadratic-broken line regressions were *** results agree with previously published data evaluating the SID Ca requirement of fast-growth broilers from hatch to d 10.

关键词： Apparent ileal digestibility Digestible calcium Requirements Retention Tibia ash

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Thomas' calculus based on the original work by George B. Thomas ; as revised by ross l. Finney, Maurice D. Weir, and Frank R. Giordano ross l. Finney...[et al.] Updated 10th ed. /

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Thomas' calculus based on the original work by George B. Tho...

Context-dependent integrated stress resistance promotes a global invasive pest

2003年

作者： ross l. Finney...[et al.]

0321116364 (pbk.) 9780321116369 (pbk.)

ISBN: (纸本)0201755270

0321116364 (pbk.) 9780321116369 (pbk.)

关键词： Calculus

来源：畅想之星图书光盘版（南... 评论

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畅想之星图书光盘版（南通市图书馆镜像）

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Insect Science 2022年第6期29卷 1790-1804页

作者： Vimbai l.Tarusikirwa ross N.Cuthbert Reyard Mutamiswa Casper Nyamukondiwa Department of Biological Sciences and Biotechnology Botswana International University of Science and TechnologyPalapyeBotswana GEOMAR Helmholtz-Zentrum fur Ozeanforschung Kiel KielGermany School of Biological Sciences Queen's University BelfastNorth ern IrelandUnited Kingdom Department of Zoology and Entomology University of the Free StateBloemfonteinSouth Africa Tugwi-Mukosi Multidisciplinary Research Institute Midlands State UniversityGweruZimbabwe Department of Zoology and Entomology.Rhodes University MakhandaSouth Africa

In nature,insects concurrently face multiple environmental stressors,a sce-nario likely increasing with climate *** stress resistance(ISR)thus often improves fitness and could drive invasiveness,but how physiological mechanisms influ-ence invasion has lacked ***,we investigated cross-tolerance to abiotic stress factors which may influence range limits in the South American tomato pinworm a global invader that is an ecologically and socially damaging crop ***,we tested the effects of prior rapid cold-and heat-hardening(RCH and RHH),fasting,and desiccation on cold and heat tolerance traits,as well as starvation and desiccation sur-vivability between *** life *** effects on critical thermal minima(CT_(min))and maxima(CT_(max))were inconsistent,showing significantly deleterious effects of RCH on adult CT_(max) and CT_(min) and,conversely,beneficial acclimation effects of RCH on larval CT_(min).While no beneficial effects of desiccation acclimation were recorded for desiccation tolerance,fasted individuals had significantly higher survival in adults,whereas fasting negatively affected larval ***,fasted and desiccation acclimated adults had significantly higher starvation tolerance,showing strong evidence for *** results show context-dependent ISR traits that may promote *** fitness and *** the frequent overlapping occurrence of these divergent stressors,ISR reported here may thus partly elucidate the observed rapid global spread of *** into more stressful environments than *** information is vital in determining the underpinnings of multistressor responses,which are fundamental in forecasting species responses to changing environments and management responses.

关键词： acclimation cross-talk cross-tolerance invasive species thermal tolerance tomato leaf miner

Aortic valve replacement reduces mortality in moderate aortic stenosis:a systematic review and meta-analysis

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Journal of Geriatric Cardiology 2023年第1期20卷 61-67页

作者： Kyle B Franke Dimple Bhatia ross l Roberts-Thomson Peter J Psaltis Adelaide Medical School The University of AdelaideAdelaideAustralia Vascular Research Centre Lifelong Health ThemeSouth Australian Health and Medical Research InstituteAdelaideAustralia Department of Cardiology Royal Adelaide HospitalAdelaideAustralia

BACKGROUND With the introduction of transcatheter aortic valve replacement and an evolving understanding of the natural progression and history of aortic stenosis,the potential for earlier intervention in appropriate patients is promising;however,the benefit of aortic valve replacement in moderate aortic stenosis remains *** Pubmed,Embase,and the Cochrane library databases were searched up until 30th of December 2021 using keywords including moderate aortic stenosis and aortic valve *** reporting all-cause mortality and outcomes in early aortic valve replacement(AVR)compared to conservative management in patients with moderate aortic stenosis were *** ratios were generated using random-effects meta-analysis to determine effect *** 3470 publications were screened with title and abstract review,which left 169 articles for full-text *** these studies,7 met inclusion criteria and were included,totalling 4,827 *** studies treated AVR as a time-dependent co-variable in cox-regression multivariate analysis of all-cause *** with surgical or transcatheter AVR was associated with a 45% decreased risk of all-cause mortality(HR=0.55[0.42-0.68],I2=51.5%,Pll studies were representative of the overall cohort with appropriate sample sizes,with no evidence of publication,detection,or information biases in any of the *** In this systematic review and meta-analysis,we report a 45% reduction in all-cause mortality in patients with moderate aortic stenosis who were treated with early aortic valve replacement compared to a strategy of conservative *** control trials are awaited to determine the utility of AVR in moderate aortic stenosis.

关键词： aortic stenosis analysis

Effect of protein sources on performance characteristics of turkeys in the first three weeks of life

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Animal Nutrition 2019年第4期5卷 396-406页

作者： Megan l.ross Dervan D.S.l.Bryan Dawn A.Abbott Henry l.Classen Department of Animal and Poultry Science University of SaskatchewanSaskatoonS7N 5A8SaskatchewanCanada

The effect of nutrition during the early life of turkey poults has a long-lasting impact on bird *** study assessed the digestibility of 5 high protein feed ingredients(soybean meal [SBM],corn gluten meal [CGM],canola protein concentrate [CPC],fish meal [FM],and porcine meal [PCM]) in broiler chickens,as well as their use in turkey pre-starter diets fed to 21 d of *** first experiment(5 × 2 factorial arrangement) determined nitrogen corrected apparent metabolizable energy(AMEn) and apparent ileal amino acid digestibility(AIAAD) of each ingredient in broiler chickens at 5 and 21 d of age,using 6 replications of 30 and 8 chicks,*** the second experiment(completely randomized design),4 replication pens,containing 23 d-old poults,were randomly assigned to one of 5 dietary *** diets were formulated based on the AMEn and AIAAD values derived in the first experiment,and consisted of a high SBM control diet,and 4 additional diets with either CPC,FM,PCM or CGM replacing 25% of the protein supplied by SBM in the control *** analysis was completed using Proc Mixed in SAS *** contrasts were used to compare treatments in the second *** were identified at P lue at d 5 was higher than that at d *** ileal amino acid digestibility increased with age for most amino acids(AA),but the response was AA and protein source *** largest average increase in AIAAD between 5 and 21 d of age was observed for *** of CPC,FM,PCM,or CGM increased body weight up to 14 d,in comparison to poults fed the SBM diet,but feed efficiency and water consumption were not *** ileum digesta moisture values were higher for birds fed SBM when compared to those fed *** results demonstrate that combining SBM with CPC,FM,PCM,or CGM improves poult performance during the first 14 d of

关键词： Soybean meal Corn gluten meal Canola meal Fish meal Porcine meal Turkeys