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Neural Regeneration Research 2025年第2期20卷 475-476页

作者： Jackson Powell Tobias Steinschaden rose Horowitz Yuanquan Song Raymond G.Perelman Center for Cellular and Molecular Therapeutics The Children’s Hospital of PhiladelphiaPhiladelphiaPAUSA The Neuroscience Graduate Group University of PennsylvaniaPhiladelphiaPAUSA Department of Pathology and Laboratory Medicine University of PennsylvaniaPhiladelphiaPAUSA Medical University of Vienna Center for Brain ResearchDepartment of NeuroimmunologyViennaAustria

Neural damage or degeneration is at the crux of many diseases,and treatment of these diseases will require the development of therapeutics to enhance and guide neural *** intrinsic and extrinsic factors dictate a neuron’s ability to regenerate,and the combination of these factors results in the great regenerative capacity of the peripheral nervous system(PNS)and the poor regenerative capacity of the central nervous system(CNS)following *** the core of a neuron’s function is its ability to relay electrochemical signals,and a neuron’s excitability is a key factor in its ability to *** works have focused on the changes in neuronal electrophysiological properties,firing patterns,and ion flux after injury,which differentially activate signaling pathways at the core of *** role of glia in neuron regeneration has long been studied.

关键词： degeneration firing system

Distributional Considerations for Transboundary Risk Governance of Environmental Threats

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International Journal of Disaster Risk Science 2018年第4期9卷 445-453页

作者： Adam rose Price School of Public Policy University of Southern California

Most policy analyses of both short-term and long-term disasters focus on aggregate impacts of their costs and the benefits of policy remedies. Distributional considerations relating to the costs of these disasters and the benefits of their risk management, however, are very important in many cases. This article examines two broad categories of cases in terms of distributional considerations. The first category is where transboundary considerations strongly affect risk governance, as in the case of climate change. The second relates to ordinary, short-term disasters, which include fewer, but still important, transboundary issues. Climate change policy requires information regarding the distribution of impacts and policy responses across countries because it is a global *** disasters involve transboundary considerations much less frequently, so the attention typically shifts to the distribution of benefits and costs within a jurisdiction. In both cases distributional information is needed to evaluate the equity of policies and to provide information for public participation in the policy process. This article offers modeling and policy approaches to address these issues.

关键词： Climate change Disasters Distributional effects Policy analysis Risk governance Transboundary impacts

Promising hollow multi-shelled structures:discovering the temporal-spatial ordering

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National Science Review 2020年第11期7卷 1763-1764页

作者： rose Amal School of Chemical Engineering University of New South Wales

Harvesting incident photons is the first step in a photo-induced process such as photocatalysis, photovoltaics or photodetection, which crucially governs the process performance. Unfortunately,extensive energy losses are observed in this step due to severe surface reflections and limited optical paths of the shortwavelength light [1]. Thus,

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Improved tabledng behavior of paracetamol in the presence of polyvinylpyrrolidone additive: Effect of mixing conditions

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Particuology 2019年第2期17卷 9-18页

作者： Ayuk Agbor rose Waseem Kaialy School of Pharmacy Faculty of Science and Engineering University of Wolverhampton Wolverhampton WV1 1LY UK

Monoclinic paracetamol (PA) is notorious as a poorly compactible model drug. Polyvinylpyrrolidone (PVP) is a polymer that can act as an effective binder to improve the mechanical properties of PA. It is surprising however that the role of mixing conditions on the physicochemical and mechanical properties of PA-PVP mixtures has not been reported previously. The results of this work showed that PA-PVP mixtures containing 5%(w/w) PVP prepared using high energy mixing conditions had considerably smaller particle size distributions and higher cohesivities than mixtures prepared using low energy mixing conditions. Solid-state analysis did not detect any change in the monoclinic crystalline form of PA after mixing with PVP. The following rank order of tabletability for PA-PVP mixtures was obtained according to the mixing condition: low shear-medium shear< dry high shear< wet high shear< high-speed homogenization. A higher level of hydrogen bonding was detected in the mixtures prepared via high energy mixing conditions than in those prepared using low energy mixing conditions. Mixing is therefore a critical process that needs to be optimized during the preparation of in teractive mixtures for tableting.

关键词： Direct compression Interactive mixtures Hydrogen bonding Mechanical properties Physicochemical properties Tableting

Size specific boldness associated with differences in resource requirements and habitat use: a cross-sectional study in hermit crabs

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Current Zoology 2023年第3期69卷 360-366页

作者： Mark Briffa rose Archer School of Biological and Marine Sciences University of PlymouthPlymouth PL48AAUK

Animal personality is often studied within compressed periods of observation that represent narrow windows in comparison to animal *** much is known about the relations between repeatable personality traits and cross-situational behavioral plasticity,less is known about how such traits might differ across age classes or life history *** conducted a cross-sectional study of startle response duration in 3 size classes of Pagurus bernhardus,the common European hermit *** defined size classes using transitions in the preferred species of gastropod shells that accompany growth,and this change in preference is in turn associated with a transition from intertidal to subtidal *** with small-and medium-sized intertidal individuals the larger subtidal hermit crabs behaved cautiously by showing startle responses of greater duration following *** responses were also repeatable within all 3 size classes,confirming the presence of animal personality in intertidal hermit crabs and demonstrating that this pattern is retained within the largest size classes,which have undergone the transition from intertidal to subtidal ***,there was a trend for the pattern of repeatable startle response durations to increase with size class,with the highest value for repeatability and the greatest range of startle response durations being present within the large subtidal *** greater range of startle responses indicates that the longer startle response durations in some larger individuals are more likely due to developmental changes with age and habitat use than reflecting selection against the boldest individuals during earlier stages of life.

关键词： boldness development habitat hermit crab personality resources

A Reduced-Form Rapid Economic Consequence Estimating Model:Application to Property Damage from U.S. Earthquakes

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International Journal of Disaster Risk Science 2013年第1期4卷 20-32页

作者： Nathaniel Heatwole Adam rose National Center for Risk and Economic Analysis of Terrorism Events(CREATE) University of Southern CaliforniaLos AngelesCA 90089USA Price School of Public Policy University of Southern CaliforniaLos AngelesCA 90089USA

Modeling the economic consequences of disasters has reached a high level of maturity and accuracy in recent years. Methods for providing reasonably accurate rapid estimates of economic losses, however, are still limited. This article presents the case for “reduced-form” models for rapid economic consequence estimation for disasters, and specifies and statistically estimates a regression equation for property damage from significant U.S. earthquakes. Explanatory variables are of two categories:(1) hazard-related variables pertaining to earthquake characteristics;and(2) exposure-related variables pertaining to socioeconomic conditions. Comparisons to other available earthquake damage estimates indicate that our Reduced-Form Model yields reasonably good results, including several statistically significant variables that are consistent with a priori hypotheses. The article concludes with a discussion of how the research can be enhanced through the collection of data on additional variables, and of the potential for the extension of the reduced-form modeling approach to other hazard types.

关键词： earthquake hazard maturity

Smoking prevalence in the area of responsibility of the German Ministry of Defense——results of the employee survey in the context of occupational health management

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Military Medical Research 2020年第3期7卷 343-349页

作者： Stefan Sammito Annika Claus Dirk-Matthias rose Department I 3 Research&Development Air Force Centre of Aerospace MedicineCologneGermany Occupational Medicine Faculty of MedicineOtto-von-Guericke-University of MagdeburgMagdeburgGermany Institute for Teachers’Health Institute of OccupationalSocial and Environmental Medicine of the Johannes-Gutenberg University MainzMainzGermany

Background:Tobacco use,correlated with reduced physical fitness,is one of the leading causes of avoidable death *** increases the risk of dementia and can shorten the lifespan by 10 *** the German Armed Forces(Bundeswehr),figures on smoking behavior have not been comprehensively *** study analyzes current data in a large sample from this ***:Based on an employee survey as part of the Occupational Health Management System,data on smoking behavior from 13,326 participants were analyzed in relation to age,gender,professional status,education level and membership in military operational units versus other ***:Smoking behavior varied significantly(Polder),gender,professional status,military agency membership status,and education level(the lower the education level,the higher the smoking rates).With the exception of the downward trend in smoking behavior with increasing age among civilian employees,these results were all significant(P<0.005).Conclusions:This data analysis shows that smoking prevalence among personnel in the area of responsibility of the Federal Ministry of Defense is comparable to the current data from corresponding surveys of the German *** on gender,they generally show values that are slightly above those of the German *** well-known trend in the general population of decreasing smoking prevalence with increasing age is also seen in this ***,there are considerable differences in the smoking prevalence among individual subgroups(professional status,agency,gender,education level).The data show that particular young soldiers in the armed forces should be the target group for further preventive measures.

关键词： Prevention Smoking Military Health promotion

Potentially fatal haemobilia due to inappropriate use of an expanding biliary stent

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World Journal of Gastroenterology 2003年第10期9卷 2377-2378页

作者： Rakesh Rai John rose Derek Manas Hepatobiliary Surgery and Liver Transplant Unit Freeman HospitalNewcastleUK Department of Interventional Radiology Freeman HospitalNewcastleUK Hepatobiliary Surgery and Liver Transplant Unit.Freeman Hospital.Newcastle.UK

AIM: To highlight the fatal complication caused by expanding biliary stents and the importance of avoiding use of expanding stent in potentially curable ***: Arteriobiliary fistula is an uncommon cause of haemobilia. We describe a case of right hepatic artery pseudoaneurysm causing arteriobiliary fistula and presenting as severe malena and cholangitis, in a patient with a mesh metal biliary stent. The patient had lymphoma causing bile duct ***: Gastroduodenoscopy failed to establish the exact source of bleeding and hepatic artery angiography and selective embolisation of the pseudo aneurysm successfully controlled the ***: Bleeding from the pseudo aneurysm of the hepatic artery can be fatal. Mesh metal stents in biliary tree can cause this complication as demonstrated in this *** mesh metal stent insertion should be avoided in potentially benign or in curable conditions. Difficulty in diagnosis and management is discussed along with the review of the literature.

关键词： Aneurysm, False Biliary Fistula Female Hemobilia Hemorrhage Humans Middle Aged Stents

NAILING THE HOT WATER&HEATING SYSTEMS IN HIGH PERFORMANCE HOMES:ONE BUILDER’S RESEARCH PROJECT

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Journal of Green Building 2014年第2期9卷 51-61页

作者： Martha rose Martha rose Construction Master Builders Association of King and Snohomish Counties

In 2005,Martha rose Construction Inc.(MRC)upgraded the specs in their Built Green Certified homes to include high performance and healthy home *** 2007,MRC joined the Department of Energy’s Builders Challenge *** than 1%of the market builders in the country work under this umbrella,which has a tag line“Research Towards Net Zero.”It charges its builders with striving to reach net zero while still being replicable and affordable.A recent name change better illustrates the goal:“DOE Zero Energy Ready Home.”With the help of the mechanical engineers that work with DOE on this program,Martha rose Construction began trying different space and hot water heating *** projects the company undertakes are small by development standards and they are custom designed for each site,even though they are sold on the speculative marketplace after *** goal was,and still is,to find the magic bullet for water and space heating that combines affordability with efficiency and *** the calculated heat loads are extremely low due to super insulation,air sealing,and heat recovery ventilation(HRV),it no longer makes monetary sense to have a fancy heating *** Building America engineers promote the KISS(keep it simple stupid)concept!In this article,we will look at the factors that led Martha rose Construction to try different heating types and the level of builder and buyer satisfaction with each *** projects’mechanical systems will be reviewed and we will end with what is likely the best recommendation going forward for a high performance *** author is a builder in the Seattle marketplace,and has made a career in the construction industry for over 41 years.

关键词： Built Green High Performance Home Airtight Homes Comfort HRV system Certified Net Zero Healthy Home