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Inter.ational Jour.al of Disaster.r.sk Science 2015年第4期6卷 321-334页

作者： Junko Mochizuki Sor.vit Vitoontus Bandula Wickr.mar.chchi Stefan Hochr.iner.Stigler.Keith Williges r.inhar. Mechler.ros Sovann Inter.ational Institute for.Applied Systems Analysis(IIASA) Asian Disaster.Pr.par.dness Center.ADPC) National Committee for.Disaster.Management(NCDM)

Iter.tive r.sk management and r.sk-sensitive public investment planning ar. incr.asingly seen as essential elements of natur.l disaster.r.silience. This ar.icle assesses the disaster.r.sk facing the hazar.-pr.ne Southeast Asian countr. of Cambodia and discusses its fiscal pr.par.dness and need for.pr.active disaster.r.sk *** study pr.vides a bottom-up assessment of flood and cyclone r.sks to public and pr.vate buildings including educational str.ctur.s, health facilities, and housing and estimates the total dir.ct economic damage to r.nge fr.m appr.ximately USD 304 million for.a 5-year.r.tur. per.od event to USD 2.26 billion for.a 1000-year.r.tur. per.od event. These estimates wer. fur.her.analyzed using the fiscal r.sk due to disaster., which indicates that Cambodia will likely face a r.sour.e gap whenever.a hazar. as lar.e as that of a 28-year.r.tur. per.od event str.kes. Given the fr.quent occur.ence of disaster. and r.pid accumulation of capital assets taking place, pr.active r.sk r.duction is highly advisable. But inter.iews with national policymaker. also r.vealed that ther. ar. a number.of bar.ier. to effective r.sk r.duction and management in Cambodia. The gener.l lack of awar.ness r.gar.ing r.sk-based concepts and the limited availability of local r.sk infor.ation necessitate a continued and sustained effor. to build iter.tive r.sk management in Cambodia.

关键词： Cambodia Fiscal impact Iter.tive r.sk management Macr.economic impact Natur.l disaster.r.sk

Scavenging Action of Zinc and Gr.en Tea Polyphenol on Cisplatin and Nickel Induced Nitr.c Oxide Gener.tion and Lipid Per.xidation in r.ts

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Biomedical and Envir.nmental Sciences 2004年第4期17卷 402-409页

作者： SEEMA JOSHI S. K. HASAN r.MESH CHANDr. M. M. HUSAIN r. C. Sr.VASTAVA Isabella Thobur. P. G. College Faizabad Road Lucknow 226 007 IndiaIndustrial Toxicology Research Centre P. O. Box. 80 M. G. Marg Lucknow 226 001 IndiaIndustrial Toxicology Research Centre P. O. Box. 80 M. G. Marg Lucknow 226 001 IndiaIndustrial Toxicology Research Centre P. O. Box. 80 M. G. Marg Lucknow 226 001 IndiaR.C.Srivastava Scientist 'F'and Area Coordinator Analytical Toxicology Industrial Toxicology Research Centre P.O.Box80M.G.Marg Lucknow226001UP.INDIA

Objective Toxic metal ions have been implicated in the gener.tion of r.active oxygen species (ros) and nitr.c oxide (NO). Metallothionines (MT) and plant flavonoids have been r.por.ed in the inter.ention against oxidative damage. We investigated the effect of zinc induced MT and gr.en tea polyphenol (GTP) in r.ducing the oxidative r.sponses induced by nickel and platinum. Methods Zinc (10 mg/kg b. wt, sc) was administer.d to r.ts twice at a gap of 24hr. and GTP (10 mg/100 mL in dr.nking water. was fed ad libitum for.8 days. Nickel chlor.de (150 umol/***, ip) and cisplatin (50 mmol/kg ***, sc) was administer.d to r.ts 24 h after.Zn or.GTP pr.-tr.atment. Animals of all the gr.ups wer. sacr.ficed 16 hr. after.tr.atment and biochemical mar.er. for.toxicity wer. monitor.d. r.sults Zinc or.GTP pr.-tr.atment caused significant pr.tection against nickel or.cisplatin enhanced mor.ality in r.ts, and r.duction in lipid per.xidation and NO. Conclusion It is pr.posed that inhibition of ros and NO by GTP and zinc may pr.ve useful as a selective phar.acological agent in the amelior.tion of metal toxicity.

关键词： Gr.en tea polyphenol Zinc Nitr.c oxide Lipid Per.xidation Nickel Cisplatin

Nur.er. Fer.ilizer.Application Incr.ases r.ce Gr.wth and Yield in r.infed Lowlands with or.without Post-Tr.nsplanting Cr.p Str.ss

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Amer.can Jour.al of Plant Sciences 2015年第18期6卷 2878-2892页

作者： Chhay ros Peter.F. White r.char. W. Bell Depar.ment of For.ign Affair. and Tr.de Australian Embassy Phnom Penh Cambodia Depar.ment of Agr.cultur. and Food WA Baron-Hay Court S. Perth Australia School of Veter.nar. and Life Sciences Murdoch University Murdoch Australia

In r.infed lowlands, the beneficial effects on r.ce (Or.za sativa) yield fr.m fer.ilizing the seedling nur.er. may depend on the occur.ence of water.and nutr.ent str.ss after.tr.nsplanting into the mainfield. The aim of the study was to test the effect of seedling age and nur.er. fer.ilisation on r.ce yield when plants exper.enced nutr.ent and water.str.ss r.gimes after.tr.nsplanting. The fir.t exper.ment, conducted dur.ng the wet season in a low-fer.ility r.infed lowland field in south-east Cambodia, examined the effect of thr.e levels of nitr.gen (N), phosphor.s (P) and cow manur. (CM) application to the nur.er. and thr.e ages of seedlings at tr.nsplanting (4, 6 and 9 weeks after.sowing: WAS) on the gr.wth of a tr.ditional photoper.od-sensitive r.ce cultivar. Incr.asing fer.ilizer.application to the nur.er. incr.ased shoot dr. weight and gr.in yield at each age of seedling tr.nsplanted. Shoot dr. weight and gr.in yield fr.m seedlings tr.nsplanted 6 WAS wer. 20% and 10% higher.than those fr.m the seedlings tr.nsplanted at the other.ages. Seedlings tr.nsplanted at 4 WAS, which exper.enced a tempor.r. submer.ence for.3 days after.tr.nsplanting, r.cor.ed 5% gr.ater.seedling mor.ality fr.m the unfer.ilized than fer.ilized nur.er. soil. The taller.seedlings tr.nsplanted at 6 WAS exper.enced less mor.ality despite mor. sever. submer.ence. The second exper.ment was conducted at seven r.infed lowland sites across Cambodia to test the benefit of N alone and N+P application to the nur.er. on r.ce yields in far.er.’ fields. In four.out of seven tr.als, gr.in yield incr.ases aver.ged 13% with N+P applied to the nur.er. wher.as N alone incr.ased gr.in yield at two sites and depr.ssed yield at two. Over.ll, fer.ilizer.application in the nur.er. pr.duced mor. vigor.us seedlings with higher.nutr.ent concentr.tion which sur.ived submer.ence and gr.w better.with or.without dr.ught or.nutr.ent str.ss after.tr.nsplanting, leading to incr.ased yields of r.ce. The beneficial effect of n

关键词： Nutr.ent Uptake Seedling Age Seedling Vigor Submer.ence

Continuous Apomor.hine Infusion in Patients with Advanced Par.inson’s Disease with Var.ing Degr.es of Functional Impair.ent

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Jour.al of Behavior.l and Br.in Science 2016年第10期6卷 393-403页

作者： Gabr.el Salazar.Mar.a Fr.goso Jonatan Mar.í Noelia Mar.ín rosó Ber.al Neur.logy Depar.ment Hospital Consorci Sanitari de Terrassa Barcelona Spain Day-Hospital Nur.ing Depar.ment Hospital Consorci Sanitari de Terrassa Barcelona Spain

Intr.duction: Continuous apomor.hine infusion (CAI) is effective in impr.ving complications in advanced Par.inson’s disease (APD). The effectiveness and toler.nce of CAI in patients with APD with var.ing degr.es of functional impair.ent was studied. Methods: In this compar.tive obser.ational study, consecutive APD who star.ed tr.atment with CAI wer. included. They wer. classified into two gr.ups of functional impair.ent: A) moder.te (Schwab and England (S & E) = 60% - 80% and Hoehn and Yahr.(H & Y) = 2 - 3;Gr.up (A), and (B) sever. (S & E 3;Gr.up B). Clinical follow-up was per.or.ed with concomitant medication and CAI adjustment at 3, 6 and 12 months. Clinical evaluation included a dyskinesia diar. and AIMS, S & E, NPI, NMSS and HADS questionnair.s. r.sults: Eighteen patients par.icipated (A = 9 and B = 9) with EP diagnosed 7 (A) and 13 (B) year. befor.. Their.baseline dose of levodopa was 728 mg (A) and 925 mg (B), which did not change dur.ng follow-up. Dopamine agonists wer. pr.gr.ssively r.duced in both gr.ups. Pr.gr.ssive titr.tion of CAI r.sulted in abandonment of apomor.hine bolus administr.tion. Both gr.ups exper.enced impr.vements in all var.ables, higher.in gr.up A;motor.fluctuations = 69% (A), 53% (B);AIMS = 82% (A), 71 (B);S & E = 32% (A), 18% (B);NMS = 62% (A), 19% (B);NPI = 75% (A), 50% (B);HADS (anxiety) = 26% (A), 21% (B);HADS (depr.ssion) = 52% (A), 31% (B). Adver.e effects wer. gener.lly mild and r.solved without r.ducing CAI dose. Ther. wer. no withdr.wals. Conclusions: Patients with APD and moder.te functional impair.ent tr.ated with CAI may obtain gr.ater.functional, cognitive and emotional impr.vement than patients mor. sever.ly affected.

关键词： Par.inson’s Disease Apo Mor.hine Continuous Dopaminer.ic Stimulation

Logistic r.gr.ssion Modelling for.Complex Sur.ey Data with an Application for.Bed Net Use in Mozambique

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Open Jour.al of Statistics 2016年第5期6卷 898-907页

作者： Sheyla r.dr.gues Cassy Isabel Natár.o M. rosár.o Mar.ins Depar.amento de Matemática e Infor.ática Faculdade de Ciências Universidade Eduardo Mondlane Maputo Mo&ccedil ambique CMA Depar.amento de Matemática Faculdade de Ciências e Tecnologia Universidade Nova de Lisboa Caparica Portugal Global Health and Tr.pical Medicine GHTM Instituto de Higiene e Medicina Tropical IHMT Universidade Nova de Lisboa UNL Lisboa Portugal

Logistic r.gr.ssion Models have been widely used in many ar.as of r.sear.h, namely in health sciences, to study r.sk factor. associated to diseases. Many population based sur.eys, such as Demogr.phic and Health Sur.ey (DHS), ar. constr.cted assuming complex sampling, i.e., pr.babilistic, str.tified and multistage sampling, with unequal weights in the obser.ations;this complex design must be taken into account in or.er.to have r.liable r.sults. However. this ver. r.levant issue usually is not well analyzed in the liter.tur.. The aim of the study is to specify the logistic r.gr.ssion model with complex sample design, and to demonstr.te how to estimate it using the r.softwar. sur.ey package. Mor. specifically, we used Mozambique Demogr.phic Health and Sur.ey data 2011 (MDHS 2011) to illustr.te how to cor.ect for.the effect of sample design in the par.icular.case of estimating the r.sk factor. associated to the pr.bability of using mosquito bed nets. Our.r.sults show that in the pr.sence of complex sampling, appr.pr.ate methods must be used both in descr.ptive and infer.ntial statistics.

关键词： Sur.ey Logistic r.gr.ssion Complex Samples Bed Net Malar.a DHS

应对可转移多黏菌素耐药性--饲料添加剂来源的白屈菜红碱具有双重效应

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Engineer.ng 2024年第1期32卷 163-173页

作者： Huangwei Song Xueyang Wang Muchen Zhang Zhiyu Zou Siyuan Yang Tian Yi Jianfeng Wang Dejun Liu Yingbo Shen Chongshan Dai Zhihai Liu Timothy r.Walsh Jianzhong Shen Congming Wu Yang Wang National Key Labor.tor. of Veter.nar. Public Health and Safety College ofVeterinary MedicineChina Agricultural UniversityBeijing 100193China Guangdong Labor.tor. for.Lingnan Moder. Agr.cultur. Guangzhou 510642China State Key Labor.tor. for.Zoonotic Diseases Key Laboratory of Zoonosis ResearchMinistry of EducationInstitute of ZoonosisCollege of Veterinary MedicineJilin UniversityChangchun 130015China College of Chemistr. and Phar.aceutical Sciences Qingdao Agricultural University.Qingdao 266109China Ineos-Oxfor. Institute of Antimicr.bial r.sear.h Department of BiologyUniversity of OxfordOxford OX13SZUK

The emer.ence and spr.ad of the mobile colistin-r.sistance gene,mcr.1,and its var.ants pose achallenge to the use of colistin,a last-r.sor. antibiotic used to tr.at sever. infections caused by extensively dr.g-r.sistant(XDr.Gr.m-negative *** adjuvants ar. a pr.mising str.tegy to enhance the efficacy of colistin against colistin-r.sistant pathogens;however.few studies have consider.d the effects of adjuvants on limiting r.sistance-gene *** found that cheler.thr.ne(4 mg·L^(-1))der.ved fr.m Macleaya cor.ata extr.ct,which is used as an animal feed additive,r.duced the minimal inhibitor. concentr.tion(MIC)of colistin against an mcr.1 positive Escher.chia coli(***)str.in by 16-fold(fr.m 2.000 to 0.125 mg·L^(-1)).eliminated appr.ximately 10^(4) colony-for.ing units(CFUs)of an mcr.1-car.ying str.in in a mur.ne intestinal infection model,and inhibited the conjugation of an mcr.1-bear.ng plasmid in vitr.(by>100-fold)and in a mouse model(by up to 5-fold).A detailed analysis r.vealed that cheler.-thr.ne binds to phospholipids on bacter.al membr.nes and incr.ases cytoplasmic membr.ne fluidity,ther.by impair.ng r.spir.tion,disr.pting pr.ton motive for.e(PMF),gener.ting r.active oxygen species(ros),and decr.asing intr.cellular.adenosine tr.phosphate(ATP)levels,which subsequently downr.gu-lates mcr.1 and conjugation-associated *** dual effects of cheler.thr.ne can expand the use of antibiotic adjuvants and may pr.vide a new str.tegy for.cir.umventing mobile colistin r.sistance.

关键词： Cheler.thr.ne Antibiotic adjuvant Conjugation inhibitor Colistin mcr.1 Dual effects

Effect of Solution Concentr.tion on the Electrospr.y/Electrospinning Tr.nsition and on the Cr.stalline Phase of PVDF

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Mater.als Sciences and Applications 2010年第4期1卷 247-252页

作者： Lígia Mar.a Manzine Costa rosár.o Elida Suman Br.tas r.naldo Gr.gor.o 不详

A study was conducted r.gar.ing the effect of concentr.tion of poly (vinylidene fluor.de) (PVDF)/N,N-dimethylfor.amide (DMF) and PVDF/DMF/acetone solutions on the tr.nsition between electrospr.y and electrospinning and on the for.ation of the ? and ? cr.stalline phases of PVDF. The cr.stalline phases pr.sent in the samples, cr.stallinity and mor.hology wer. deter.ined by Four.er.tr.nsfor. infr.r.d spectroscopy (FTIr., differ.ntial scanning calor.metr. (DSC) and scanning electr.n microscopy (SEM), r.spectively. Low concentr.tion solutions r.sulted in films consisting of small dr.plets (electrospr.y) containing pr.dominantly the ? phase. High concentr.tion solutions r.sulted in a non-woven mesh of nano-to-micr.n diameter.fiber. (electrospinning) containing exclusively the ? phase. These r.sults showed that, the for.ation of this phase in the electrospinning is r.lated mainly to the solvent evapor.tion r.te, and not to dr.wing exper.enced by the polymer.dur.ng the pr.cess. Solvent type affected the amount of cr.stalline phase pr.sent, the boundar. concentr.tion between the two pr.cesses and the aver.ge diameter.of fiber.. Meshes pr.cessed by electrospinning display a degr.e of cr.stallinity higher.than the films obtained by electrospr.y.

关键词： Poly(Vinylidene Fluor.de) (PVDF) Electrospinning Electrospr.y Cr.stalline Phase Fiber. Mor.hology

A Clinical Study on Diabetes, Cholester.mia and Hyper.ipemia

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中国针灸 1995年第S2期15卷 388-389页

作者： Luz Mar.a ros(Centr. Integr.l de SaludMedicina Tr.ditional ChinaSagitar.o 198Fr.cc.Con fr., CP 64860Monter.ey, Nuevo Leon, Mexico)

ＡＣｌｉｎｉｃａｌＳｔｕｄｙｏｎＤｉａｂｅｔｅｓ，ＣｈｏｌｅｓｔｅｒｅｍｉａａｎｄＨｙｐｅｒｌｉｐｅｍｉａ￥ＬｕｚＭａｒｉａＲｏｓ（ＣｅｎｔｒｅＩｎｔｅｇｒａｌｄｅＳａｌｕｄＭｅｄｉｃｉｎａＴｒａｄｉｔｉｏｎａｌＣｈ... 详细信息

ＡＣｌｉｎｉｃａｌＳｔｕｄｙｏｎＤｉａｂｅｔｅｓ，ＣｈｏｌｅｓｔｅｒｅｍｉａａｎｄＨｙｐｅｒｌｉｐｅｍｉａ￥ＬｕｚＭａｒｉａＲｏｓ（ＣｅｎｔｒｅＩｎｔｅｇｒａｌｄｅＳａｌｕｄＭｅｄｉｃｉｎａＴｒａｄｉｔｉｏｎａｌＣｈｉｎａＳａｇｉｔａｒｉｏ１９８Ｆｒ...

关键词： A Clinical Study on Diabetes Cholester.mia and Hyper.ipemia

Pr.jecting Health Outcomes for.Por.uguese Ageing Population: Challenges and Oppor.unities

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Health 2014年第14期6卷 1874-1882页

作者： Mar.a do rosár.o Oliveir. Mar.ins Inês Campos r.dr.gues Ter.sa Fer.eir. r.dr.gues CEPESE—Centr. de Estudos da Populaç ã o Economia e Sociedade Universidade do Porto Porto Portugal Unidade de Saúde Pública Inter.acional e Bioestatística Instituto de Higiene e Medicina Tropical Universidade Nova de Lisboa Lisboa Portugal

Objectives: To pr.ject health outcomes for.the per.od 2011-2031, in the Por.uguese population aged 65 year. and over. consider.ng the expected changes in its demogr.phic and educational str.ctur.. Methods: Demogr.phic pr.jections wer. pr.duced using the multistate cohor. component method. Logistic r.gr.ssion models wer. fitted to estimate cur.ent differ.nces in health outcomes, using data fr.m the Por.uguese Health Sur.ey. Such differ.nces wer. applied to the pr.jection r.sults, in or.er.to pr.ject the pr.valence of “poor. self-r.por.ed health status, functional limitations and disability. r.sults: Our.r.sults point to a futur. impr.vement in the consider.d health outcomes. The pr.valence of “poor. self-r.por.ed health status, functional limitations and disability will decr.ase in both gender., but will continue to be higher.among women than men. Discussion: Beyond age and gender. other.deter.inants of health, like education, should be consider.d when studying the possible evolution of health outcomes in an ageing population.

关键词： Pr.jections Aging Educational Level Self-r.por.ed Health Status Functional Limitations and Disability

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桃红酒待字闺中的少女

城色 2012年第11期 130-133页

作者： rosé Wine

有爱酒人将桃红酒形容为葡萄酒中的"牛仔裤"——花样繁多并且百搭。在欧洲,不管年轻人还是资深酒友,都喜欢桃红酒。樱桃粉、三文鱼肉红、浅桃红、杏桃色、浆果红……各种高雅又有个性的颜色,光视觉上就能够很好地为你开开胃。

关键词：葡萄酒消费干红食材酿酒师红葡萄酒优质葡萄酒烹饪方式法国波尔多品酒师葡萄酒业