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Effects of Supplemented Shengmai San (SMS) on Blood Biochemistry and HSP72 Expression in Peripheral Blood of Flying-saucer Athletes before and after High Temperature Training

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Journal of Integrative Medicine（双语） 2020年第2期9卷 17-21页

作者： Jian Shen feng Xu Bin Jin rongquan Zhang Zhejiang College of Sports HangzhouZhejiang311231China Zhejiang PRC Shoot Archerg&Bicycle Management Centre ChangxingZhejing313100China

Objective:The purpose of this paper is to study the effects of supplemented Shengmai San on the expression of heat shock protein 72(HSP72)and blood biochemistry in peripheral blood of flying-saucer athletes before and after high temperature training,so as to provide experimental basis for enhancing thermal endurance and preventing heat disease of flying-saucer athletes with anti-heat disease ***:24 flying-saucer athletes from Zhejiang province were selected and divided into two groups,including control group and traditional Chinese medicine group with 12 people in each *** them,those who did not drink supplemented Shengmai San were in the control group,while those who drank it were in the traditional Chinese medicine *** summer training,high temperature training task was carried out for 2 ***-saucer athletes in traditional Chinese medicine group were given supplemented Shengmai San before training every morning and *** venous blood of each group was extracted before experiment and 2 weeks later and lymphocyte HSP72 content,blood routine and biochemical indexes were determined ***:Before the experiment,there were no abnormal phenomenon blood routine,biochemical test value and HSP72 expression in the control group and the traditional Chinese medicine *** comparison,there was no significant difference(P>0.05).After the high temperature training,the expression of HSP72 in the Chinese medicine group was significantly higher than that before the training and control group(P<0.05).There were significant differences in white blood cell count before and after the experiment(P<0.05).Conclusion:Taking supplemented Shengmai San can significantly increase expression of HSP72 in up-regulation of flying saucer athletes after thermal stimulation,thus enhancing thermal tolerance and preventing thermal diseases.

关键词： Supplemented Shengmai San Flying saucer athletes Training of high temperature HSP72

The Observation of Blood Biochemistry and HSP72 Expression Changing Rules in Peripheral Blood of Flying-saucer-athletes under High Temperature Training

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Journal of Integrative Medicine（双语） 2020年第2期9卷 8-11页

作者： Jian Shen feng Xu Bin Jin rongquan Zhang Zhejiang College of Sports Hangzhou311231China Zhejiang PRC Shoot Archer&Bicycle Management Centre Changxing313100China

Objective:To study the effect of training under high temperature on blood and heat shock protein 72(HSP72)expression of flying saucer ***:The numbers of training group and control group are ***-four flying saucer athletes in Zhejiang province were selected and randomly divided into training group and control group,15 in each *** venous blood of each group was taken before and after the *** HSP72 content of lymphocyte,blood routine and biochemical indexes were measured ***:There was significant difference in white blood cell in training group count before and after the experiment(P<0.05).The expression of HSP72 and the white blood cell in training group was higher than that control group(P<0.05).Conclusions:Organism could be affected and turned to stress state due to training under high *** is necessary to provide the safeguard for the flying saucer athletes under high temperature in order to prevent the damage.

关键词： Flying Saucer Athletes Blood routine experiment Biochemical index Heat shock protein 72 Training under high temperature

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论一阶量词及其语义解释

外语学刊 2025年第1期 106-112页

作者：张力锋南京大学哲学系南京210023

一阶量词具有极大的普遍性,可以统一地处理由于论域变化造成的无限多日常量词。基于一阶语言公式的严格递归构造,重叠量化式归根结底可诉诸原子句和逻辑常项(特别是量词)的意义,得到准确的理解。代入解释挑战标准的量词解释,将量化语句... 详细信息

一阶量词具有极大的普遍性,可以统一地处理由于论域变化造成的无限多日常量词。基于一阶语言公式的严格递归构造,重叠量化式归根结底可诉诸原子句和逻辑常项(特别是量词)的意义,得到准确的理解。代入解释挑战标准的量词解释,将量化语句的真还原为相应去量化语句的代入实例的真,而代入实例被规定或设定为真未必是在存在论意义上,从而既能刻画一阶推理的有效性,又可确保量词作为逻辑常项的本体论中立性。但量化语句并未因代入量词的本体论中立而在语言实践中被剥夺存在含意,它的存在含意下沉至名字及命名关系;克里普克建构的代入量化语义佐证了以上论点,可以驳斥将代入量化看作一种特殊对象量化的误读,代入量化只表明量化语句的真值条件是某些代入实例为真,而不是将量化语句翻译或还原为那个代入实例。

关键词：量词满足代入解释本体论承诺真值条件名字

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网络空间安全技术发展趋势研究

信息安全研究 2025年第1期11卷 2-4页

作者：冯登国中国科学院中国科学院软件研究所

网络空间安全是一个长期演进、发展和变化的过程,在这个过程中,新问题随着新场景、新技术不断出现.而新的问题出现以后就需要思考如何解决,主要来自2个方面:一个是新的场景,主要是应用场景、计算场景;另一个是新的技术,如人工智能技术... 详细信息

网络空间安全是一个长期演进、发展和变化的过程,在这个过程中,新问题随着新场景、新技术不断出现.而新的问题出现以后就需要思考如何解决,主要来自2个方面:一个是新的场景,主要是应用场景、计算场景;另一个是新的技术,如人工智能技术、量子计算技术.在解决新问题的过程中,网络空间安全技术得到了新的发展.

关键词：网络空间安全人工智能技术量子计算长期演进应用场景发展趋势研究计算场景

Peri-centrosomal localization of small interfering RNAs in C. elegans

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Science China Life Sciences 2025年

作者： Qile Jin Xuezhu feng Minjie Hong Ke Wang Xiangyang Chen Jiewei Cheng Yan Kuang Xiaoyue Si Mingjing Xu Xinya Huang Shouhong Guang Chengming Zhu Department of Obstetrics and Gynecology The First Affiliated Hospital of USTC The USTC RNA Institute Hefei National Research Center for Physical Sciences at the Microscale School of Life Sciences Division of Life Sciences and Medicine Biomedical Sciences and Health Laboratory of Anhui Province University of Science and Technology of China School of Basic Medicine Anhui Medical University

The centrosome is the microtubule-organizing center and a crucial part of cell division. Centrosomal RNAs(cnRNAs) have been reported to enable precise spatiotemporal control of gene expression during cell division in many species. Whether and how cnRNAs exist in C. elegans are unclear. Here, using the nuclear RNAi Argonaute protein NRDE-3 as a reporter, we observed potential peri-centrosome localized small interfering(si)RNAs in C. elegans. NRDE-3 was previously shown to associate with pre-mRNAs and pre-rRNAs via a process involving the presence of complementary siRNAs. We generated a GFP-NRDE-3 knock-in transgene through CRISPR/Cas9 technology and observed that NRDE-3 formed peri-centrosomal foci neighboring the tubulin protein TBB-2, other centriole proteins and pericentriolar material(PCM)components in C. elegans embryos. The peri-centrosomal accumulation of NRDE-3 depends on RNA-dependent RNA polymerase(RdRP)-synthesized 22G siRNAs and the PAZ domain of NRDE-3, which is essential for siRNA binding. Mutation of eri-1, ergo-1, or drh-3 significantly increased the percentage of pericentrosome-enriched NRDE-3. At the metaphase of the cell cycle, NRDE-3 was enriched in both the peri-centrosomal region and the spindle. Moreover, the integrity of centriole proteins and pericentriolar material(PCM) components is also required for the peri-centrosomal accumulation of NRDE-3. Therefore, we concluded that siRNAs could accumulate in the pericentrosomal region in C. elegans and suggested that the peri-centrosomal region may also be a platform for RNAi-mediated gene regulation.

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指向课程协同育人的跨学科主题学习路径设计

教学与管理 2025年第2期 24-28页

作者：殷凤张慧上海市浦东教育发展研究院上海200127 上海市浦东新区高桥镇小学上海200137

核心素养体系本身关注的是综合性素养,以落实“培养什么人”的教育目标。加强课程综合,注重关联,开展跨学科主题学习,强化课程协同育人功能,是新一轮课程改革的重要指向。以关联内容结构、融通核心素养、创设进阶活动、落实以评促学作... 详细信息

核心素养体系本身关注的是综合性素养,以落实“培养什么人”的教育目标。加强课程综合,注重关联,开展跨学科主题学习,强化课程协同育人功能,是新一轮课程改革的重要指向。以关联内容结构、融通核心素养、创设进阶活动、落实以评促学作为跨学科学习设计的路径,精准把握跨学科学习的取向,避免学科间的简单“拼盘”,从而真正实现课程的协同育人。

关键词：跨学科主题学习协同育人核心素养

Microplastic and nanoplastic exposure and risk of diabetes mellitus

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World Journal of Clinical Cases 2025年第3期13卷 24-29页

作者： Hui-Yi Hsiao Chung-Yi Nien Ruei-feng Shiu Wei-Chun Chin Tzung-Hai Yen Department of Biomedical Sciences College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina Center for Tissue Engineering Chang Gung Memorial HospitalLinkouTaoyuan 33305TaiwanChina Department of Life Sciences National Central UniversityZhongli 320317TaoyuanTaiwanChina Center of Excellence for The Oceans Taiwan Ocean UniversityKeelung 20224TaiwanChina Institute of Marine Environment and Ecology Taiwan Ocean UniversityKeelung 20224TaiwanChina Department of Chemical and Materials Engineering University of California MercedMercedCA 95343United States Department of Nephrology Clinical Poison CenterChang Gung Memorial HospitalLinkou 33305TaoyuanTaiwanChina School of Traditional Chinese Medicine College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina

The issue of plastic pollutants has become a growing *** microplastics(MPs)(particle size<5 mm)and nanoplastics(NPs)(particle size<1μm)can cause DNA damage,cytotoxicity,and oxidative stress in various *** primary known impacts of microplastic/nanoplastic are observed in the liver and respiratory system,leading to hepatotoxicity and chronic obstructive pulmonary *** research on the effects of MPs and NPs on diabetes is still in its early stages,there are potential *** editorial highlights the risk to diabetics from co-exposure to contaminants and MPs/NPs,supported by evidence from animal studies and the various chemical compositions of MPs/NPs.

关键词： Microplastics Nanoplastics Plastic pollution,Diabetes mellitus Insulin resistance

人工智能与政治安全形态演变:一项系统研究的尝试

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国际安全研究 2025年第1期43卷 54-72,156,157页

作者：封帅薛世锟上海国际问题研究院网络空间国际治理研究中心上海国际问题研究院上海200233

在人工智能时代,政治安全的内涵正在被不断深化和持续拓展,各国面临的政治安全风险也愈发复杂。根据系统科学理论,政治安全可以构建为一种政治安全系统,包含正反要素、四大结构面与动态稳定的功能。人工智能在经历从游离到输入的时序过... 详细信息

在人工智能时代,政治安全的内涵正在被不断深化和持续拓展,各国面临的政治安全风险也愈发复杂。根据系统科学理论,政治安全可以构建为一种政治安全系统,包含正反要素、四大结构面与动态稳定的功能。人工智能在经历从游离到输入的时序过程后,作为一种新的要素与政治安全系统发生互动。人工智能与政治安全的互动遵循“技术—应用—风险—系统”的逻辑过程,并实现对系统内其他要素的影响。这种影响全面且深刻,使得人工智能开始大面积嵌入政治安全系统,重构了政治安全结构。政治安全正在面临人工智能所带来的更复杂的风险形态,包括权力安全、制度安全与价值安全在内的政治安全内部生态都将发生深刻变化,推动整个政治安全形态经历深刻的变革。

关键词：人工智能政治安全国家安全系统科学

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侵犯商业秘密罪评价标准的修正与规范解读

海南大学学报（人文社会科学版） 2025年第1期43卷 185-194页

作者：冯明昱张勇南京师范大学法学院江苏南京210023 华东政法大学刑事法学院上海200042

《刑法修正案(十一)》完成了侵犯商业秘密罪由数额犯到情节犯的全面转型,但未跟进更新的司法解释易使得司法实务将情节犯作数额犯化处理,仅关注数额要素对于犯罪评价的影响。侵犯商业秘密罪所保护的是复合法益:一是商业秘密权利人对商... 详细信息

《刑法修正案(十一)》完成了侵犯商业秘密罪由数额犯到情节犯的全面转型,但未跟进更新的司法解释易使得司法实务将情节犯作数额犯化处理,仅关注数额要素对于犯罪评价的影响。侵犯商业秘密罪所保护的是复合法益:一是商业秘密权利人对商业秘密享有的私权利,二是市场竞争秩序,后者又可还原为具体的个人法益——商业秘密权。以此为逻辑起点,侵犯商业秘密罪的评价体系应当坚持区分性、形式与实质相统一、强保护的原则,建构综合评价体系。各要素不可单独作为入罪标准,而应综合考量,建构起以数额要素为主,非数额要素为辅的“情节严重”解释体系。

关键词：侵犯商业秘密罪情节犯数额犯