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Carbon Neutrality 2022年第1期1卷 141-152页

作者： ronghua Chen G.H.Su Kui Zhang School of Nuclear Science and Technology Xi’an Jiaotong UniversityXi’an 710049China

Striving to peak carbon emissions and achieve carbon neutrality(known as the"Dual-Carbon"goal)is an inevitable requirement for elevating the environmental resource constraints and realizing harmonious coexistence between the mankind and the *** the energy system,nuclear energy offers various advantages,such as high energy density,low carbon emission,strong environmental adaptability and large potential for energy co-generation and *** is one of the supporting energy sources for the transformation and upgradation of the energy system to a clean,efficient and low-carbon *** this paper,the opportunities and challenges for innovation-driven nuclear energy development in the fields of electricity generation,hydrogen production,heat supply and seawater desalination under the goal of"Dual-Carbon"are discussed and ***,the relevant research on improving the safety and economy of the pressurized water reactor(PWR)and sodium-cooled fast reactor(SFR)conducted by the Nuclear THermal-hydraulic research Lab(NuTHeL)of Xi’an Jiaotong University is briefly introduced.

关键词： "Dual-Carbon"goal Nuclear energy NuTHeL PWR SFR

Lower and upper bounds of Dirichlet eigenvalues for totally characteristic degenerate elliptic operators

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Science China Mathematics 2014年第11期57卷 2235-2246页

作者： CHEN Hua QIAO ronghua LUO Peng XIAO DongYuan School of Mathematics and Statistics Wuhan University

Let λkbe the k-th Dirichlet eigenvalue of totally characteristic degenerate elliptic operator-ΔB defined on a stretched cone B0 ■ [0,1) × X with boundary on {x1 = 0}. More precisely,ΔB=(x1αx1)2+ α2x2+ + α2xnis also called the cone Laplacian. In this paper,by using Mellin-Fourier transform,we prove thatλk Cnk2 n for any k 1,where Cn=(nn+2)(2π)2(|B0|Bn)-2n,which gives the lower bounds of the Dirchlet eigenvalues of-ΔB. On the other hand,by using the Rayleigh-Ritz inequality,we deduce the upper bounds ofλk,i.e.,λk+1 1 +4n k2/nλ1. Combining the lower and upper bounds of λk,we can easily obtain the lower bound for the first Dirichlet eigenvalue λ1 Cn(1 +4n)-12n2.

关键词： cone Laplacian cone Sobolev spaces Dirichlet eigenvalues upper bounds of eigenvalues lower bounds of eigenvalues

Inhibition of the Antigen-Induced Activation of RBL-2H3 Cells by Gab2 siRNA

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Cellular & Molecular Immunology 2008年第6期5卷 433-438页

作者： Feng Huang Xiaoyun Tong Huaming Deng Liangqing Fu ronghua Zhang Department of Pharmacology College of Pharmacy Jinan UniversityGuangzhou 510632 China The First Affiliated Hospital of Yunnan College of Traditional ChineseMedicine Kunming 650021 China Department of Clinical Pharmacology 307 Hospital Beijing 100850China These authors contributed equally to this work.

Gab2 plays an important role in FcεRI mediated signal events which lead to degranulation from mast cells. The present study was designed to investigate the effect of the synthetic Gab2 （scaffolding adapter Grb2-associated binder 2） siRNA on the antigen-induced activation of RBL-2H3 cells. A double stranded siRNA against Gab2- mRNA was synthesized and transfected into RBL-2H3 cells. After 6 h, cells were then sensitized with dinitrophenyl （DNP）-specific IgE overnight and challenged with dinitrophenyl-human serum albumin （DNP-HSA） to induce mast cell degranulation before supernatants were collected. Effects of Gab2 siRNA on antigen-induced release of β-hexosaminidase and histamine, cytokine production and regulation of the proteins in the pathway were measured by enzymatic assay, EIA, ELISA and Western blotting. Treatment with Gab2 siRNA significantly decreased Gab2 expression, inhibited the FcεRI-mediated mast cell release of β-hexosaminidase and histamine, reduced the production of IL-4 and TNF-α and inhibited the phosphorylation of Akt, PKC8 and p38 mitogen-activated protein kinase （MAPK）. Data showed that Gab2 siRNA could suppress the antigen-induced activation of RBL-2H3 cells and suggested a possible mechanism through inhibition of signaling molecules downstream of Gab2 in the 2＋ FcεRI-mediated Ca -independent pathway. Furthermore, potential usefulness of Gab2 knock-down as a method for inhibition of mast cell-mediated allergic reactions was demonstrated. Cellular ＆ Molecular Immunology. 2008; 5（6）：433-438.

关键词： RNA interference Gab2 RBL-2H3 cell

A NOVEL DRIVING STRATEGY FOR DYNAMIC SIMULATION OF HOISTING ROPE WITH TIME-VARYING LENGTH

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International Journal of Modeling, Simulation, and Scientific Computing 2013年第3期4卷 54-70页

作者： JINJIE WANG GUOHUA CAO YANDONG WANG ronghua WU School of Mechatronic Engineering China University of Mining and Technology No.1 Da Xue Road XuzhouJiangsu Province 221116P.R.China

A simulation method for investigating the vibration behavior of hoisting rope with time-varying length is *** previously creating markers in the *** software package,the parametric model of the rope wound along helix is established based on the concentrated-mass theory with multi-degree of freedom(multi-DOF).A novel driving strategy,cooperating fixed joints with angle sensors under the control of driving script,is proposed to substitute conventional contact *** on the hoisting rope in the sinking winch mechanism,an equivalent discretization model is obtained with complicated boundary conditions *** differential equations of motion of the hoisting system are formulated employing Lagrange’s equation and numerically solved using Runge–Kutta *** simulation indicates that the horizontal swing is decreased in principle and the simulation with 800 discrete ropes is not performed more than 61 ***,this feasible strategy could not only guarantee the accuracy but also promote simulation efficiency and *** motion curves exported from ADAMS simulation coincide with one in numerical simulation,which validates both the numerical model and the driving strategy.

关键词： Winding modeling driving strategy MSC.ADAMS numerical validation.

Investigating the effect of online and offline reputation on the provision of online counseling services: A case study of the Internet hospitals in China

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Frontiers of Engineering Management 2022年第4期9卷 563-576页

作者： ronghua XU Tingting ZHANG Qingpeng ZHANG School of Management Zhejiang University of TechnologyHangzhou 310014China School of Data Science City University of Hong KongHong KongChina

The sustainable development of Internet hospitals and e-health platforms relies on the participation of patients and physicians,especially on the provision of health counseling services by *** objective of our study is to explore the factors motivating Chinese physicians to provide online health counseling services from the perspectives of their online and offline *** collect the data of 141029 physicians from 6173 offline hospitals located in 350 cities in *** on the reputation theory and previous studies,we incorporate patients’feedback as physicians’online reputation and incorporate physicians’offline professional status as physicians’offline *** show that physicians’online reputation significantly and positively influence their online counseling behaviors,whereas physicians’offline reputation significantly and negatively influence their online counseling *** conclude that physician’s online and offline reputations show a competitive and substitute relationship rather than a complementary relationship in influencing physicians to provide online counseling services in Internet *** possible explanation for the substitute relationship could be the constraints of limited time and effort of physicians.

关键词： Internet hospitals physicians’online counseling online reputation offline reputation

Transient flow control for an artificial open channel based on finite difference method

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Science China(Technological Sciences) 2011年第4期54卷 781-792页

作者： SHANG YiZi LIU ronghua LI TieJian ZHANG Cheng WANG GuangQian State Key Laboratory of Hydroscience and Engineering Tsinghua UniversityBeijing 100084China School of Renewable Energy North China Electric Power University Beijing 102206 China

The particular challenges of modeling control systems for the middle route of the south-to-north water transfer project are *** channel dynamics are approximated by well-known Saint-Venant nonlinear partial differential *** better control purpose,the finite difference method is used to discretize the Saint-Venant equations to form the state space model of channel *** avoid calculation divergence and improve control stability,balanced model reduction together with poles placement procedure is proposed to develop the control *** entire process to obtain this scheme is described in this paper,important application issue is considered as *** results show the adopted techniques are properly used in the control scheme design,and the system is able to drive the discharge to the demanded set point or maintain it around a reasonable range even if comes across big withdrawals.

关键词： the south-to-north water transfer project control scheme Saint-Venant equations model reduction pole placement

Long-term surface water changes and driving cause in Xiong'an,China:from dense Landsat time series images and synthetic analysis

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Science Bulletin 2018年第11期63卷 708-716页

作者： Chunqiao Song Linghong Ke Hang Pan Shengan Zhan Kai Liu ronghua Ma Key Laboratory of Watershed Geographic Sciences Nanjing Institute of Geography and LimnologyChinese Academy of SciencesNanjing 210008China Department of Geography University of CaliforniaLos AngelesLos AngelesCA 90095United States School of Earth Sciences and Engineering Hohai UniversityNanjing 211100China Department of Geographic Information Science Nanjing UniversityNanjing 210023China

China＇s government statement recently reported the plan of constructing Xiong＇an New Area, which aims to phase out some extra capital functions from Beijing and to explore an innovative urban development mode with the priority in eco-environmental protection. The New Area is located in the semi-arid North China Plain （NCP） and is home to NCP＇s largest natural freshwater wetland, Baiyangdian Lake. A comprehensive realization of surface water dynamics would be crucial for policy-makers to outline a sustainable environment development strategy for New Area. In this study, we used a total of 245 time slices of cloud-free Landsat images to document the continuous changes of water bodies within Xiong＇an City dur- ing 1984-2016 and to provide detailed evidence of water presence and persistency states and changes under the influences of climate change and human actions. Our results reveal that the New Area water body areas varied dramatically during the past 33 years, ranging from 0.44 km^2 in April 1988 to 317.85 km^2 in February 1989. The change of surface water area was not characterized by a monotonically decreasing tendency. The evolution processes can be divided into four sub-stages： the first extreme desiccation in mid-1980s, the wet stage with the most extensive inundation areas and strong inter-annual fluctuations from late-1988 to late 1999, another desiccation stage in early 2000s, and the overall recovering stage between 2007 and 2016. We also mapped the maximum water inundation extents and frequencies of all-season, pre-wet season （February-May） and post-wet season （September-December） for the 33 years and different sub-periods. Although there is good agreement between time series of surface water area evolution in the New Area and station-based precipitation and evaporation variations, multipie lines of evidences reviewed in previous research indicate that the degraded Baiyangdian Lake was also tightly associated with human activities from various aspects, inc

关键词： Xiong'an New Area Surface water Baiyangdian Lake Remote sensing Climate change Landsat

Wilson's Disease and Hepatic Transplantation

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2002年第2期22卷 142-143页

作者： TANG ronghua(唐荣华) XUE Zheng(薛峥) YE Qifa(叶启发) Department of Neurology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 Department of Neurology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 Institute of Organ Transplantation Tongji Medical College Huazhong University of Science and Technology Wuhan 430030

Summary: To investigate the changes in neurological symptoms and signs, as well as serum copper, serum ceruloplasmin after hepatic transplantation in patients with Wilson’s disease, neurological symptoms and signs, serum copper, serum ceruloplasmin before and after hepatic transplantation in 18 patients with Wilson’s disease were observed, and those changes were followed up in 20 non-operative controls treated with penicillamine. Our results showed that the neurological symptoms and signs, serum copper and serum ceruloplasmin were improved in the operative group but deteriorated in the non-operative control group. Our study showed that hepatic transplantation is better than penicillamine in the treatment of Wilson’s disease.

关键词： Wilson's disease hepatic transplantation clinical investigation

Research on PTFE Dispersions Filled with Nanometer ZnO

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Journal of Rare Earths 2004年第Z2期22卷 157-161页

作者： Han Jianmin Li Weijing Cui Shihai Zhao Yang Li ronghua Wang Jinhua School of Mechanical Electronic and Control EngineeringBeijing Jiaotong UniversityBeijing 100044China

PTFE dispersion composites filled with nanometer ZnO were successfully prepared by controlling stirring speed and using ultrasonic mixture with no damage to PTFE dispersion. Properties of PTFE composites, such as wear rate, friction coefficient and thermal conductivity coefficient were tested respectively. Also, the grain size of nanometer filler in composites were observed by different methods, such as small angle X-ray scattering (SAXS), transmission electron microscopy (TEM) and dynamic light scattering particle size distribution analyzer (DLSPSDA). Results show that nanometer ZnO fillers can further improve properties of PTFE-based composite, and its properties varies with the content of the fillers.

关键词： PTFE dispersion nanometer ZnO composite wear property

Synthesis and Antimicrobial Activity of Some New 4H-Pyr rolo [ 1,2-a] b enzimid azoles

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Chemical Research in Chinese Universities 2014年第5期30卷 755-758页

作者： JIANG Yuliang HAN Qiaorong SHEN ronghua ZANG Xinxin WANG Bingxiang Jiangsu Key Laboratory of Biofunctional Materials School of Chemistry and Materials Science Nanjing Normal University Nanjing 210097 P. R. China

Some new 4H-pyrrolo[1,2-a]benzimidazoles（2a-2f） have been synthesized. The structures of these compounds were confirmed by IR, tH NMR, mass spectroscopy and elemental analysis. Compound 2a was further confirmed by X-ray diffraction. The in vitro antimicrobial activities of these compounds were determined against some gram-positive bacteria, gram-negative bacteria and fungi and their drug-resistant isolates in comparison with standard drugs. Antimicrobial results indicate that compounds 2c, 2d and 2e show moderately active antibacterial properties, their minimum inhibitory concentrations are from 12.5 μg/mL to 125 μg/mL. In the series, the most active compound against C. albicans is compound 2fwith an MIC value of 31.25 μg/mL.

关键词： 4H-Pyrrolo[1,2-a]benzimidazole Anti-bacterial Anti-fungal