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学科类培训机构缩减对学生在校时长的影响:基于“双减”政策的评估研究

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华东师范大学学报（教育科学版） 2025年第1期43卷 37-48页

作者：陆伟魏易杭州师范大学经亨颐教育学院杭州311121 北京大学中国教育财政科学研究所北京100871

对校外培训机构的治理整顿是“双减”改革的重要内容之一。本文使用大众点评网学科类培训机构的商铺信息,结合高德地图地理编码和搜索POI应用接口,以及全国中小学教育信息化使用情况调查等数据,实证检验了学科类校外培训机构缩减对学生... 详细信息

对校外培训机构的治理整顿是“双减”改革的重要内容之一。本文使用大众点评网学科类培训机构的商铺信息,结合高德地图地理编码和搜索POI应用接口,以及全国中小学教育信息化使用情况调查等数据,实证检验了学科类校外培训机构缩减对学生在校时长的影响。研究发现:(1)“双减”期间,全国层面学科类培训机构的缩减比例约为88%。(2)学校周边学科类培训机构的缩减程度越高,学生每天待在学校内的时间也越多,也即校内教育与校外教育出现一定程度的替代,且这种替代效应在弱势阶层群体中更为明显;在北上广深四个一线城市不明显,但在其他众多二三线城市可以观察到。(3)学校周边学科类培训机构的缩减程度越高,学生在学校内完成课后作业的概率也越高,而在校外辅导班完成课后作业的概率则越低;但培训机构缩减对学生完成课后作业的总时长没有影响。

关键词： “双减” 学科类培训机构校外培训在校时长

Multiphysics simulation and optimization of the in-situ beneficiation process of ilmenite minerals from lunar regolith

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Science China Earth Sciences 2025年第1期68卷 195-207页

作者： Peng ZHANG Xin LIU Guanghui LIU wei DAI Hanzhe YANG Haibo ZHENG Zhi WANG Ran NIU Yifan BAI Yang ZHANG Chengbao LIU Ge YANG Junwei YANG Guang ZHANG Technology and Engineering Center for Space Utilization Chinese Academy of Sciences Beijing Hegong Simulation Co. Ltd

The exploration and utilization of lunar resources have become the major objectives of future lunar exploration missions. The classified collection and processing of lunar minerals is the basic prerequisite for the in-situ exploration and utilization of lunar resources. In this study, we propose a scheme for in-situ separation of magnetic minerals from lunar soils using the dry magnetic separation method. The scheme can realize the purpose of separating magnetic minerals from lunar regolith by altering the motion trajectory of lunar regolith particles with different magnetic properties. Detailed modeling of the dry magnetic separation device is conducted, and the three-dimensional distribution of magnetic parameters is calculated and analyzed. Based on the characterization and analysis of the Chang E-5's samples, the morphologies and physical parameters of lunar regolith particles are modeled and simulated. A discrete element simulation of the motion process of lunar regolith particles under multi-physical field conditions is performed, and the influences of key parameters on the beneficiation performance of lunar magnetic minerals are investigated. Our results indicate that optimal separation and beneficiation of lunar regolith particles can be achieved under specific conditions of magnetic field strength and drum speed. Additionally, we analyze the effects of lunar weak gravity conditions and the charged nature of lunar particles on the beneficiation process, showing that these factors can obviously enhance the beneficiation process of lunar ilmenites. This study demonstrates the feasibility of using the dry magnetic separation method for the beneficiation of magnetic minerals from lunar regolith, providing a theoretical basis for the scientific tasks of collecting, processing, and utilizing lunar mineral resources.

关键词： Lunar regolith In-situ resource utilization Magnetic separation Classified sampling

TMED3 promotes prostate cancer via FOXO1a and FOXO3a phosphorylation

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Oncology Research 2025年第1期33卷 161-169页

作者： XIUWANG wei JIANBO LIANG HUANWEN HUANG DAMING YANG XINXIN WANG XIUJIA WANG CHANGSHENG CHEN KAIQIANG LI TAISEN PANG BIN HU FENGNING WU Department of Urology The People’s Hospital of Guangxi Zhuang Autonomous RegionNanning530000China Department of Rehabilitation The People’s Hospital of Guangxi Zhuang Autonomous RegionNanning530000China

Background:Transmembrane emp24 trafficking protein 3(TMED3)is associated with the development of several tumors;however,whether TMED3 regulates the progression of prostate cancer remains *** and Methods:Short hairpin RNA was performed to repress TMED3 in prostate cancer cells(DU145 cells)and in a prostate cancer mice model to determine its function in prostate cancer in vitro and in ***:In the present study,we found that TMED3 was highly expressed in prostate cancer *** vitro,shTMED3 treatment suppressed the proliferation,invasion,and migration and promoted the apoptosis of DU145 ***,the Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis showed a strong correlation between TMED3 and forkhead box O transcription factor(FOXO)***,TMED3 inhibition efficiently decreased FOXO1a and FOXO3a *** vivo,TMED3 downregulation suppressed the apoptosis,growth,and metastasis of prostate cancer cells via FOXO1a and ***:The present findings show that TMED3 participates in the regulation of prostate cancer progression via FOXO1a and FOXO3a phosphorylation,thereby revealing a novel mechanism underlying prostate cancer development and suggesting that TMED3 inhibition may serve as a novel strategy for prostate cancer treatment.

关键词： Prostate cancer Transmembrane emp24 trafficking protein 3(TMED3) forkhead box O transcription factor(FOXO) Proliferation Apoptosis

High-performance transparent graphene-based antennas

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Science China Technological Sciences 2025年

作者： Chaoye HONG Lusong wei weijia WANG Youmei TANG Qinghai ZHU Jiangtao HUANGFU Mingsheng XU College of Integrated Circuits State Key Laboratory of Silicon and Advanced Semiconductor Materials Zhejiang University College of Information Science and Electronic Engineering Zhejiang University

With the continuous development of wireless communication technology, applications in the military, aerospace,and vehicle wireless communication sectors have demanded miniaturized and aesthetically pleasing antennas. Transparent antennas, which combine the advantages of optical and radio-frequency(RF) technologies, have become a popular research topic. However, existing transparent antennas often suffer from complex preparation processes, fragile materials, poor conductivity, and low optical transmittance. Here, we develop hybrid conductive thin films using graphene and silver nanowires,achieving a transmittance of 86% and a sheet resistance of 7.8 Ω/sq with high environmental stability. We demonstrate the suitability of this nanocomposite in two applications: a transparent ultrahigh-frequency RF-identification tag folded dipole antenna and a transparent X-band microwave half-wave dipole antenna. These antennas offer high gain, high radiation efficiency, and small size, indicating that transparent graphene-based antennas have remarkable potential for intelligent information sensor systems.

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Ca2+ cation-mediated microenvironment for electrochemical hydrodimerization of furfural

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Science China Chemistry 2025年

作者： wei Du Shuangshuang Cha Can Lei Mengxin Qu Zhongqiang Deng Ming Gong Xinhe Bao Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Fudan University State Key Laboratory of Catalysis National Laboratory for Clean Energy Collaborative Innovation Center of Chemistry for Energy Materials Dalian Institute of Chemical Physics Chinese Academy of Sciences

Furfural is one of the most important biomass-based platform molecules as sustainable precursors for chemicals and fuels. The electrochemical hydrodimerization of furfural can generate hydrofuroin, which is a promising precursor for gasoline or jet ***, steering the selectivity toward hydrodimerization under near-neutral conditions that suppress polymerization and disproportionation of furfural remains challenging. Herein, we discovered that tuning the electrolyte cations could be an effective and alternative strategy for modulating furfural reduction to the traditional electrocatalyst design. Under the optimal Ca2+cations,hydrofuroin yield could be much improved from other cations with hydrofuroin selectivity of 95.5%. The systematic characterization of the ion-centered double layer reflected the suitable sizes and charges of hydrated Ca2+for suppressing the hydrogen evolution reaction from activation of surrounding water molecules as well as encouraging furfural accumulation via non-covalent interaction for directing the electron transfer to furfurals. Ions with smaller or larger sizes can either activate local water molecules or form a crowded ionic interface that casts an adverse effect on furfural enrichment. This work not only presents an effective strategy for facilitating biomass valorization via hydrodimerization but also emphasizes the essential role of the ion-centered microenvironment for steering the electrocatalytic pathways.

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Rapid improvement of grain weight via highly efficient CRISPR/Cas9-mediated multiplex genome editing in rice

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Journal of Genetics and Genomics 2016年第8期43卷 529-532页

作者： rongfang Xu Yachun Yang Ruiying Qin Hao Li Chunhong Qiu Li Li Pengcheng wei Jianbo Yang Key Laboratory of Rice Genetic Breeding of Anhui Province Rice Research InstituteAnhui Academy of Agricultural SciencesHefei 230031China School of Agronomy Anhui Agricultural UniversityHefei 230036China

Most of the important agronomic traits in crop plants, such as yield, quality and stress response, are quantitative and jointly controlled by many genomic loci or major genes. Improving these complex traits depends on the combination of beneficial alleles at the quantitative trait loci （QTLs）. However, the conventional cross breeding method is extremely time-consuming and laborious for pyramiding multiple QTLs. In certain cases, this approach might be technically difficult because of close linkage between genes separately responsible for desirable and undesirable traits.

关键词： Rapid improvement of grain weight via highly efficient CRISPR/Cas9-mediated multiplex genome editing in rice

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Moment Redistribution Effect of the Continuous Glass Fiber Reinforced Polymer-Concrete Composite Slabs Based on Static Loading Experiment

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Structural Durability & Health Monitoring 2025年第1期19卷 105-123页

作者： Zhao-Jun Zhang Wen-wei Wang Jing-Shui Zhen Bo-Cheng Li De-Cheng Cai Yang-Yang Du Hui Huang Offshore Oil Engineering Co.Ltd. Tianjin300461China Department of Bridge Engineering School of TransportationSoutheast UniversityNanjing211189China

This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment *** experimental bending moment redistribution test was conducted on continuous GFRP-concrete composite slabs,and a calculation method based on the conjugate beam method was *** composite slabs were formed by combining GFRP profiles with a concrete layer and supported on steel beams to create two-span continuous composite slab *** methods,epoxy resin bonding,and stud connection,were used to connect the composite slabs with the steel *** experimental findings showed that the specimen connected with epoxy resin exhibited two moments redistribution phenomena during the loading process:concrete cracking and steel bar yielding at the internal *** contrast,the composite slab connected with steel beams by studs exhibited only one-moment redistribution phenomenon throughout the loading *** the concrete at the internal support cracked,the bending moment decreased in the internal support section and increased in the midspan *** the steel bars yielded,the bending moment further decreased in the internal support section and increased in the mid-span *** GFRP profiles do not experience cracking,there was no significant decrease in the bending moment of the mid-span *** test specimens experienced compressive failure of concrete at the mid-span *** results showed good agreement between the calculated and experimental values of bending moments in the mid-span section and internal support *** proposed model can effectively predict the moment redistribution behavior of continuous GFRP-concrete composite slabs.

关键词： Moment redistribution GFRP-concrete composite slabs bending moment experimental study analysis model

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假细锥香茶菜化学成分的研究

华西药学杂志 1988年第4期 208-210页

作者：卢文杰王雪芬陶一鹏陈家源韦荣芳文宜焕广西中医药研究所广西中医药研究所南宁

从假细锥香茶菜(Rabdosia coetsoides ***)叶中分离得到七个结晶单体,其中六个经鉴定分别为β-谷甾醇(Ⅰ)、乌苏酸(Ⅱ)、毛萼晶甲(Ⅳ)、毛萼乙素(Ⅴ)、5,6,4′—三羟基—7,8—二甲氧基黄酮(Ⅵ)、胡萝卜甙(Ⅶ)。

关键词：假细锥香茶菜毛萼晶甲毛萼乙素 β-谷甾醇乌苏酸胡萝卜甙 5,6,4′-三羟基—7,8— 二甲氧基黄酮

Localizing base stations with measured data:a concatenated image-based deep learning approach

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Science China(Information Sciences) 2025年

作者： Yang CHEN Ziyuan LIU Feng JIANG Hong SHEN wei XU Mengyu LI Ritao CHENG National Mobile Communications Research Laboratory Southeast University China Mobile Group Design Institute Co. Ltd.

Localization has become an indispensable function of modern cellular communication systems[1]. In a cloud radio access network （C-RAN）, the remote radio head （RRH） is the actual signal transmitter, whose location ...

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