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Aerodynamic Optimization and Flow Mechanism for a Compressor Cascade at Low Reynolds Number

Journal of Thermal Science 2025年第1期34卷 92-109页

作者： LI Lin zhang Jianshe CHEN Caiyan TAN Wei zhang Yanfeng Key Laboratory of Light-Duty Gas-Turbine Institute of Engineering ThermophysicsChinese Academy of Sciences University of Chinese Academy of Sciences National Key Laboratory of Science and Technology on Advanced Light-duty Gas-turbine

Low-Reynolds-number effect is an important factor affecting the performance of compressors and other main components of high-altitude long-endurance unmanned aerial *** improve the flow condition and reduce flow loss under the condition of high altitude and low Reynolds number(Re),this paper proposes an optimization process based on a surrogate model,which combines the class-shape transformation method(CST),the Latin hypercube sampling(LHS) method,the light gradient-boosting machine algorithm(LightGBM),and a genetic algorithm(GA) to optimize a high-subsonic compressor *** surrogate model is verified to be accurate and can be used in the optimization *** accuracy of the GA is higher than the other algorithms under common test *** optimization results are verified by numerical simulation,and the flow differences before and after optimization are compared,especially the flow within the boundary *** changing the blade shape,the optimization process adjusts the loading distribution to delay the transition of the optimized blade on the suction surface,which changes the turbulent reattachment in the laminar separation bubble(LSB) into laminar ***,the mixing loss induced by the turbulent reattachment of the LSB and the wake loss of turbulent separation at the trailing edge are significantly reduced,and the performance of the compressor profile is finally *** addition,turbulent separation of the optimized profile is delayed reducing the range of the wake region on the suction *** this optimization process,the reduction of total pressure loss coefficient at Re of 2.5×10～5,3.5×10～5,and 4.5×10～5 are 16.32%,20.76%,and 22.16%,respectively.

关键词： Reynolds number

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Enhancing the performance of the absorber of Cu2ZnSn（S， Se）4 photovoltaic materials by doping Cd2+

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Optoelectronics Letters 2025年

作者： YANG Shuqi XUE Yuming DAI Hongli WANG Luoxin zhang Haiwei BAI xin Institute of New Energy Intelligence Equipment， School of Integrated Circuit Science and Engineering， Tianjin University of Technology

Cationic doping is considered to be an effective way to improve the efficiency of Cu2ZnSn（S，Se）4（CZTSSe） photovoltaic materials. To improve the quality of the absorption layer of the crystal film， CZTSSe film was doped with some Cd to change the ratio of Cd and Zn in the precursor solution. XRD， Raman， SEM， UV-Vis spectroscopy， and other results showed that Cd successfully replaced Zn in the crystal lattice during post-selenization. The formation of harmful Zn-related defects was reduced， the grain size and crystallinity of the films were significantly increased， and the photoelectric properties of the films such as crystal quality and structural morphology were improved. As the Cd/（Cd+Zn） ratio increased from 0 to 0.35， the band gap of CZCTSSe decreased to 1.02eV. When Cd/（Cd+Zn）=0.25， the crystallinity and grain size reached the best value， and the film surface was smooth and dense， which inhibited the formation of the second phase on the surface of *** theoretical basis and experimental results showed that proper Cd doping can promote the growth of grain， so that compact CZCTSSe films with larger grain sizes and fewer holes could be prepared.

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Numerical Study of Flow and Heat Transfer Characteristics of Shell-and-Tube Molten Salt Electric Heater with Circularly Perforated Baffles

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Journal of Thermal Science 2025年第1期34卷 24-33页

作者： LIN Yongjie zhang Cancan WU Yuting zhang Yi LU Yuanwei Key Laboratory of Heat Transfer and Energy Conversion National User-Side Energy Storage Innovation Research and Development CenterBeijing University of Technology

Numerical simulations of the flow and heat transfer characteristics of four shell-and-tube molten salt electric heaters with different perforation rates was ***-and-tube electric heaters have the same geometry and tube arrangement,and all of them use single segmental baffles,but there exist four different baffle openings（φ）,i.e.,0%,2.52%,4.06%,and 6.31%.The results indicated that the reasonable baffle opening could significantly reduce the shell-side pressure drop,effectively decreasing the shell-side flow dead zone *** can eliminate the local high-temperature phenomenon on the surface of electric heating tubes,but the heat transfer coefficient is slightly *** perforated schemes significantly reduce shell-side pressure drop compared to the baseline solution without open *** particular,the φ=6.31% scheme exhibits the optimal performance among all the schemes,with a maximum reduction of up to 50.50% in shell-side pressure drop relative to the unopened holes *** heat transfer coefficient is the highest for φ=0%,exhibiting a range of5.26% to 5.73%,5.14% to 5.99%,and 7.31% to 8.54% higher than φ=2.52%,4.06%,and 6.31%,respectively,within the calculated *** composite index h/（Δp）1/3was higher for all open-hole solutions than that for the unopened-hole *** best overall performance was for φ=6.31%,which improved the composite index by15.29% to 17.18% over the unopened-hole solution.

关键词： molten salt electric heater perforated baffles heat transfer

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A Lightweight Multiscale Feature Fusion Network for Solar Cell Defect Detection

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Computers, Materials & Continua 2025年第1期82卷 521-542页

作者： Xiaoyun Chen Lanyao zhang Xiaoling Chen Yigang Cen Linna zhang Fugui zhang School of Mechanical Engineering Guizhou UniversityGuiyang550025China School of Computer Science and Technology Beijing Jiaotong UniversityBeijing100044China

Solar cell defect detection is crucial for quality inspection in photovoltaic power generation *** the production process,defect samples occur infrequently and exhibit random shapes and sizes,which makes it challenging to collect defective ***,the complex surface background of polysilicon cell wafers complicates the accurate identification and localization of defective *** paper proposes a novel Lightweight Multiscale Feature Fusion network(LMFF)to address these *** network comprises a feature extraction network,a multi-scale feature fusion module(MFF),and a segmentation ***,a feature extraction network is proposed to obtain multi-scale feature outputs,and a multi-scale feature fusion module(MFF)is used to fuse multi-scale feature information *** order to capture finer-grained multi-scale information from the fusion features,we propose a multi-scale attention module(MSA)in the segmentation network to enhance the network’s ability for small target ***,depthwise separable convolutions are introduced to construct depthwise separable residual blocks(DSR)to reduce the model’s parameter ***,to validate the proposed method’s defect segmentation and localization performance,we constructed three solar cell defect detection datasets:SolarCells,SolarCells-S,and *** and SolarCells-S are monocrystalline silicon datasets,and PVEL-S is a polycrystalline silicon *** results show that the IOU of our method on these three datasets can reach 68.5%,51.0%,and 92.7%,respectively,and the F1-Score can reach 81.3%,67.5%,and 96.2%,respectively,which surpasses other commonly usedmethods and verifies the effectiveness of our LMFF network.

关键词： Defect segmentation multi-scale feature fusion multi-scale attention depthwise separable residual block

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Propagating subduction initiation of the Caroline Plate at the Mussau Trench

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Science China Earth Sciences 2025年第1期68卷 253-269页

作者： Chun-Feng LI Yongkang DENG Tao WU Dongdong DONG Guoliang zhang Jiazheng zhang Yutao LIU Yaqing LI Fugui TANG Lulu zhang Department of Marine Sciences Zhejiang University Laboratory of Marine Mineral Resources Laoshan Laboratory Key Lab of Marine Geology and Environment Institute of Oceanology Chinese Academy of Sciences Key Lab of Ocean and Marginal Sea Geology South China Sea Institute of Oceanology Chinese Academy of Sciences Science & Technology on Integrated Information System Lab Institute of Software Chinese Academy of Sciences

New seismic imaging from the Mussau Trench confirms that, under horizontal compression on an oceanic plate boundary, it is within the young and weak oceanic plate that a trench will develop, and it is the young plate, not so long after its birth, that starts to subduct toward the old plate. The Mesozoic Pacific Plate cannot easily bend, under the joint horizontal compression and vertical gravity pull, even with a pre-existing weak zone in place and with a large age offset across the plate boundary. The bending of the Caroline Plate near the northern end of the Mussau Trench started only after a long-time span of trench migration, and/or after a prolonged transition from initial compression to trench development. Highly contrasting trench deformation and sedimentary accretion between two parallel seismic sections support an evident migration of underthrusting or significant longitudinal heterogeneity along the trench. The swift transition from underthrusting to non-thrusting can be explained by a counter-clockwise rotation of the Caroline Plate. That miniature accretionary wedges develop even before the subduction initiates imply strong compression and uplifting before the underthrusting can kick-start. Rotation of the Caroline Plate have been halted as the Mussau Trench is seismically rather quiet and the Lyra Trough to the east shows relaxational extension.

关键词： Mussau Trench Subduction initiation Seismic reflection Caroline Plate

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Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan Huang Yi-De zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang Ju-Yun Ma Peng-Peng Li Hai-Wei Pu xin-Yian Guo Jian-Gang Shen Su-Hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

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浅圆仓地震侧压力计算公式推导与分析

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地震工程学报 2025年第1期47卷 33-40页

作者：张国祥曾荣中南大学土木工程学院湖南长沙410075

仓壁侧压力是浅圆仓抗震设计的重要参数,在规范中没有给出确切的浅圆仓仓壁地震侧压力的理论计算公式。对此,基于极限平衡法,将浅圆仓看作特殊的曲线挡墙,取单位弧长的滑动楔体为研究对象,采用拟静力法与旋转地震角法简化地震力以进行... 详细信息

仓壁侧压力是浅圆仓抗震设计的重要参数,在规范中没有给出确切的浅圆仓仓壁地震侧压力的理论计算公式。对此,基于极限平衡法,将浅圆仓看作特殊的曲线挡墙,取单位弧长的滑动楔体为研究对象,采用拟静力法与旋转地震角法简化地震力以进行极限平衡分析,并推导出浅圆仓锥堆与平堆工况下的地震侧压力计算公式。通过算例分析,比较满仓状态下地震侧压力的实测数据值及理论计算值,初步验证公式的正确性。对地震侧压力进行数值模拟与参数分析,结果表明模型拟合效果良好,仓壁摩擦力影响较大,在计算中不可忽视;在平堆工况下半径取值对大直径浅圆仓地震侧压力的影响较小,可将其简化为直线挡墙计算。研究成果可为完善筒仓规范中地震侧压力的计算推导提供一定的参考依据。

关键词：浅圆仓极限平衡法滑动楔体地震侧压力拟静力法旋转地震角法

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Peficitinib suppresses diffuse-type tenosynovial giant cell tumor by targeting TYK2 and JAK/STAT signaling

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Science China Life Sciences 2025年

作者： Shan Lu Chenxi Cao Wenjia zhang Jiayi Li Jingli Yang Zisheng Huang Zhijun Wu Baitao Liu Hongjie Huang Haijun Wang Yongjian Wang Dingge Liu Zhihua zhang Kaiping Liu Gang Yang Xi Gong Hui Dai Yingjia Li Erdan Dong xin zhang Yan zhang Haihe Laboratory of Cell Ecosystem Institute of Cardiovascular Diseases The First Affiliated Hospital of Dalian Medical University Institute of Cardiovascular Sciences School of Basic Medical Sciences Peking University Health Science Center Department of Cardiology and Institute of Vascular Medicine Peking University Third HospitalState Key Laboratory of Vascular Homeostasis and Remodeling Peking University Department of Sports Medicine Peking University Third Hospital Institute of Sports Medicine of Peking University Beijing Key Laboratory of Sports Injuries Engineering Research Center of Sports Trauma Treatment Technology and Devices Ministry of Education State Key Laboratory of Membrane Biology Institute of Molecular Medicine College of Future Technology Peking University Peking University Health Science Centre Peking University Department of Immunology School of Basic Medical Sciences NHC Key Laboratory of Medical Immunology Peking University Research Center for Cardiopulmonary Rehabilitation University of Health and Rehabilitation Sciences Qingdao Hospital (Qingdao Municipal Hospital) School of Health and Life Sciences University of Health and Rehabilitation Sciences Research Unit of Medical Science Research Management/Basic and Clinical Research of Metabolic Cardiovascular Diseases Chinese Academy of Medical Sciences

Diffuse-type tenosynovial giant cell tumor(dTGCT) is a destructive but rare benign proliferative synovial neoplasm. Although surgery is currently the main treatment modality for dTGCT, the recurrence risk is up to 50%. Therefore, there is a great need for effective drugs against dTGCT with minor side effects. The Janus kinase(JAK)/signal transducer and activator of transcription(STAT) signaling plays a central role in rheumatoid arthritis(RA), a disease with similar characteristics as dTGCT, but its function in dTGCT remains *** fibroblast-like synoviocytes(FLS) and macrophages were isolated from 10 synovial tissue samples from dTGCT patients for the screening and validation of the five clinically approved JAK inhibitors to treat RA against dTGCT. Cell viability, cell death, inflammation and the activity of the JAK family members of cultured dTGCT FLS(both 2-D and 3-D) and macrophages were investigated for the efficacy of the JAK inhibitors. Here, we found that similar to RA, JAK/STAT signaling was markedly activated in the dTGCT synovium. Of the 5 JAK inhibitors, peficitinib was shown to have the most potency in addressing some of the pathological responses of dTGCT FLS and *** potency of peficitinib was much higher than pexidartinib, which is the only FDA-approved drug for dTGCT. Mechanistically, peficitinib inhibited tyrosine kinase 2(TYK2), a JAK family member necessary for the pathological progression of dTGCT FLS and macrophages. In summary, we not only revealed JAK/STAT(especially TYK2) signaling as the major mechanism underlying dTGCT, but also identified peficitinib as a promising drug against dTGCT.

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HNRNPC as a pan-cancer biomarker and therapeutic target involved in tumor progression and immune regulation

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Oncology Research 2025年第1期33卷 83-102页

作者： YUEZHOU zhang ZHAO zhang JINxin DONG CHANGAN LIU Department of Hepatobiliary Surgery The Second Affiliated Hospital of Chongqing Medical UniversityChongqing400016China Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing400016China

Background:Aberrant expression of RNA-binding proteins(RBPs)has been linked to a variety of diseases,including hematological disorders,cardiovascular diseases,and multiple types of *** nuclear ribonucleoprotein C(HNRNPC),a member belonging to the heterogeneous nuclear ribonucleoprotein(hnRNP)family,plays a pivotal role in nucleic acid *** studies have underscored the significance of HNRNPC in tumorigenesis;however,its specific role in malignant tumor progression remains inadequately ***:We leveraged publicly available databases,including The Cancer Genome Atlas(TCGA),to explore the potential involvement of HNRNPC across various ***,we performed experimental validation studies focused on liver ***:Our analysis revealed that HNRNPC is overexpressed in a wide range of common malignancies,including liver and lung cancers,and is strongly linked to unfavorable ***,HNRNPC was observed to be closely linked to tumor *** immune checkpoint analysis and immune cell infiltration assessment,HNRNPC emerged as a potential target for modulating tumor ***,silencing of HNRNPC markedly inhibited the proliferation,metastasis,and infiltration of liver cancer ***:In summary,our findings highlight HNRNPC as a prognostic marker in various cancers,including liver cancer,and suggest its involvement in shaping the tumor immune *** insights offer potential avenues for improving clinical outcomes in tumors with elevated HNRNPC expression,particularly through immunotherapeutic strategies.

关键词： Heterogeneous nuclear ribonucleoprotein C(HNRNPC) Pan-cancer analysis Tumor immunity Prognostic biomarker Immunotherapeutic target Hepatocellular carcinoma

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Control of Corner Separation for a Linear Compressor Cascade via Bionic Slanting Riblets at the Endwall

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Journal of Thermal Science 2025年第1期34卷 129-144页

作者： zhang Peng LI Yonghong CHENG Rixin Key Laboratory of Civil Aircraft Airworthiness Technology Civil Aviation University of China College of Aeronautical Engineering Civil Aviation University of China

A new passive control approach,utilizing bionic slanting riblets,is employed to mitigate the flow close to the blade endwall in a linear cascade,and its effectiveness and mechanism in controlling corner separation are investigated through numerical *** slanting riblets are positioned at the endwall upstream of the cascade channel,and the influence of riblet height,yaw angle and relative position on the control of corner separation is *** findings indicate that the application of slanting riblets can efficiently counteract corner separation across the stable operational ***,the introduction of riblets with a height of merely 0.1 times the boundary layer thickness results in a significant reduction in total pressure loss by up to 14.53%,while simultaneously enhancing the static pressure coefficient by 21.74%.Flow analysis reveals that minute vortices produced within the riblet channels tend to coalesce,forming a potent large-scale vortex near the boundary layer's base *** phenomenon results in reduced additional losses compared to conventional vortex ***,the induced vortex promotes enhanced mixing between the mainstream flow and boundary layer,inhibiting the lateral displacement of low-energy fluids within the endwall boundary ***,this delays the onset of separation vortex formation and eliminates vortex rings in the corner region,ultimately enhancing the aerodynamic efficiency of the cascade.

关键词： additional losses compressor cascade corner separation slanting riblets vortex generator

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