检索结果-南通市图书馆

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

锈蚀栓钉连接件力学性能试验研究

土木建筑与环境工程 2012年第2期34卷 15-20页

作者：荣学亮黄侨东南大学交通学院南京210096

为了解钢-混组合梁的栓钉连接件发生锈蚀后的静力工作性能,进行了4组栓钉试件的推出试验。首先通过人工电化学快速锈蚀方法使试件中的栓钉达到预定锈蚀状况,然后进行静载破坏试验,通过试验结果分析不同锈蚀状况对栓钉连接件力学性能的... 详细信息

为了解钢-混组合梁的栓钉连接件发生锈蚀后的静力工作性能,进行了4组栓钉试件的推出试验。首先通过人工电化学快速锈蚀方法使试件中的栓钉达到预定锈蚀状况,然后进行静载破坏试验,通过试验结果分析不同锈蚀状况对栓钉连接件力学性能的影响。结果表明:栓钉钉杆尤其是靠近结合面处发生锈蚀时,其极限承载力降低最大达到18%,相同荷载作用下滑移量增加,与极限荷载相对应的滑移量最大减小了12%;栓钉大头端部发生锈蚀时,对推出试件的承载力影响不大,但对栓钉连接件变形性能影响较大。

关键词：栓钉连接件锈蚀极限承载力荷载-滑移

Neuroprotective effect of Shenqi Fuzheng injection pretreatment in aged rats with cerebral ischemia/reperfusion injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2016年第1期11卷 94-100页

作者： Ying-min Cai Yong Zhang Peng-bo Zhang Lu-ming Zhen Xiao-ju Sun Zhi-ling Wang Ren-yan Xu rong-liang xue Department of Anesthesiology Second Affiliated Hospital of Xi’an Jiaotong University

Shenqi Fuzheng injection is extracted from the Chinese herbs Radix Astragali and Radix Codonopsis. The aim of the present study was to investigate the neuroprotective effects of Shenqi Fuzheng injection in cerebral ischemia and reperfusion. Aged rats（20–22 months） were divided into three groups： sham, model, and treatment. Shenqi Fuzheng injection or saline（40 m L/kg） was injected into the tail vein daily for 1 week, after which a cerebral ischemia/reperfusion injury model was established. Compared with model rats that received saline, rats in the treatment group had smaller infarct volumes, lower brain water and malondialdehyde content, lower brain Ca2＋ levels, lower activities of serum lactate dehydrogenase and creatine kinase, and higher superoxide dismutase activity. In addition, the treatment group showed less damage to the brain tissue ultrastructure and better neurological function. Our findings indicate that Shenqi Fuzheng injection exerts neuroprotective effects in aged rats with cerebral ischemia/reperfusion injury, and that the underlying mechanism relies on oxygen free radical scavenging and inhibition of brain Ca2＋ accumulation.

关键词： nerve regeneration cerebral ischemia/reperfusion Shenqi Fuzheng injection aged rats neurological function Ca 2+ oxygen free radicals NSFC grant neural regeneration

Testing Linearity in Functional Partially Linear Models

在线全文

学校读者我要写书评

暂无评论

Acta Mathematicae Applicatae Sinica 2024年第3期40卷 875-886页

作者： Fan-rong ZHAO Bao-xue ZHANG School of Mathematical Sciences Shanxi UniversityTaiyuan 030006China School of Statistics Capital University of Economics and BusinessBeijing 100070China

For the functional partially linear models including flexible nonparametric part and functional linear part,the estimators of the nonlinear function and the slope function have been studied in existing *** to test the correlation between response and explanatory variables,however,still seems to be ***,a test procedure for testing the linearity in the functional partially linear models will be proposed in this paper.A test statistic is constructed based on the existing estimators of the nonlinear and the slope ***,we prove that the approximately asymptotic distribution of the proposed statistic is a chi-squared distribution under some regularity ***,some simulation studies and a real data application are presented to demonstrate the performance of the proposed test statistic.

关键词： asymptotic theory functional partially linear model Nadaraya-Watson estimate test statistic

The Boundary Element Method for Ordinary State-Based Peridynamics

在线全文

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2024年第6期139卷 2807-2834页

作者： xue liang Linjuan Wang State Key Laboratory for Turbulence and Complex Systems Department of Mechanics and Engineering ScienceCollege of EngineeringPeking UniversityBeijing100871China CAPT-HEDPS and IFSA Collaborative Innovation Center of MoECollege of EngineeringPeking UniversityBeijing100871China School of Astronautics Beihang UniversityBeijing100191China

The peridynamics(PD),as a promising nonlocal continuum mechanics theory,shines in solving discontinuous *** to now,various numerical methods,such as the peridynamic mesh-free particlemethod(PD-MPM),peridynamic finite element method(PD-FEM),and peridynamic boundary element method(PD-BEM),have been ***-BEM,in particular,outperforms other methods by eliminating spurious boundary softening,efficiently handling infinite problems,and ensuring high computational ***,the existing PD-BEM is constructed exclusively for bond-based peridynamics(BBPD)with fixed Poisson’s ratio,limiting its applicability to crack propagation problems and scenarios involving infinite or semi-infinite *** this paper,we address these limitations by introducing the boundary element method(BEM)for ordinary state-based peridynamics(OSPD-BEM).Additionally,we present a crack propagationmodel embeddedwithin the framework ofOSPD-BEM to simulate crack *** validate the effectiveness of OSPD-BEM,we conduct four numerical examples:deformation under uniaxial loading,crack initiation in a double-notched specimen,wedge-splitting test,and threepoint bending *** results demonstrate the accuracy and efficiency of OSPD-BEM,highlighting its capability to successfully eliminate spurious boundary softening phenomena under varying Poisson’s ***,OSPDBEMsignificantly reduces computational time and exhibits greater consistencywith experimental results compared to PD-MPM.

关键词： Ordinary state-based peridynamics boundary element method crack propagation fracture toughness

All types of base conversions allowed by base editors

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2024年第2期67卷 431-433页

作者： Shun-Qing liang Wen xue RNA Therapeutics Institute UMass Chan Medical SchoolWorcester 01655USA Department of Molecular Cell and Cancer BiologyUMass Chan Medical SchoolWorcester 01655USA Department of Molecular Medicine UMass Chan Medical SchoolWorcester 01655USA Li Weibo Institute for Rare Diseases Research UMass Chan Medical SchoolWorcester 01655USA

Base editors(BEs) hold great promise as tools for introducing single-base-pair changes in both basic research and therapeutic applications(Rees and Liu,2018).Base editors are composed of a Cas9 nickase fused to a DNA-modifying enzyme,which chemically modifies nucleobases within a specific targeting window near the Cas9-binding site.

关键词： base bases allowed

波形钢腹板组合箱梁横向受力有效分布宽度研究

在线全文

学校读者我要写书评

暂无评论

湖南大学学报（自然科学版） 2016年第7期43卷 105-110页

作者：赵品荣学亮叶见曙东南大学交通学院江苏南京210096 石家庄铁道大学土木工程学院河北石家庄050043

为了研究波形钢腹板箱梁的桥面板有效分布宽度,制作了一片模型试验梁,对其进行了静载非破坏性试验,研究了此种结构桥面板的有效分布宽度变化规律.结合现行公路桥规值和有限元结果,在3种有效分布宽度计算值比较的基础上对现行公路桥规值... 详细信息

为了研究波形钢腹板箱梁的桥面板有效分布宽度,制作了一片模型试验梁,对其进行了静载非破坏性试验,研究了此种结构桥面板的有效分布宽度变化规律.结合现行公路桥规值和有限元结果,在3种有效分布宽度计算值比较的基础上对现行公路桥规值进行修正,得到了不同工况下的有效分布宽度修正系数.结果表明:按现行公路桥规计算的有效分布宽度值相比试验值、有限元结果略小,应对桥规值乘以大于1.0的修正系数,使之适用于波形钢腹板箱梁的有效分布宽度计算.

关键词：波形钢腹板箱梁模型试验桥面板有效分布宽度公路桥规

Rainbow Pancyclicity in a Collection of Graphs Under the Dirac-type Condition

在线全文

学校读者我要写书评

暂无评论

Acta Mathematicae Applicatae Sinica 2024年第2期40卷 269-274页

作者： Lu-yi LI Ping LI xue-liang LI Center for Combinatorics and LPMC Nankai UniversityTianjin 300071China School of Mathematics and Statistics Shaanxi Normal UniversityXi’an 710062China

Let G={Gi:i∈[n]} be a collection of not necessarily distinct n-vertex graphs with the same vertex set V,where G can be seen as an edge-colored(multi)graph and each Gi is the set of edges with color i.A graph F on V is called rainbow if any two edges of F come from different Gis’.We say that G is rainbow pancyclic if there is a rainbow cycle Cℓof lengthℓin G for each integerℓ2[3,n].In 2020,Joos and Kim proved a rainbow version of Dirac’s theorem:Ifδ(Gi)≥2/n for each i∈[n],then there is a rainbow Hamiltonian cycle in *** this paper,under the same condition,we show that G is rainbow pancyclic except that n is even and G consists of n copies of Kn/2,n/*** result supports the famous meta-conjecture posed by Bondy.

关键词： rainbow Hamiltonian cycle rainbow pancyclic meta-conjecture

A stable implicit nodal integration-based particle finite element method(N-PFEM)for modelling saturated soil dynamics

在线全文

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2024年第6期16卷 2172-2183页

作者： liang Wang xue Zhang Jingjing Meng Qinghua Lei Department of Earth Sciences ETH ZürichZürich8092Switzerland Department of Civil Engineering and Industrial Design University of LiverpoolLiverpoolL693BXUK Department of Civil Environmental and Natural Resources EngineeringLuleåUniversity of TechnologyLuleå97187Sweden Department of Earth Sciences Uppsala UniversityUppsala75105Sweden

In this study,we present a novel nodal integration-based particle finite element method(N-PFEM)designed for the dynamic analysis of saturated *** approach incorporates the nodal integration technique into a generalised Hellinger-Reissner(HR)variational principle,creating an implicit PFEM *** mitigate the volumetric locking issue in low-order elements,we employ a node-based strain smoothing *** discretising field variables at the centre of smoothing cells,we achieve nodal integration over cells,eliminating the need for sophisticated mapping operations after re-meshing in the *** express the discretised governing equations as a min-max optimisation problem,which is further reformulated as a standard second-order cone programming(SOCP)***,pore water pressure,and displacements are simultaneously determined using the advanced primal-dual interior point ***,our numerical model offers improved accuracy for stresses and pore water pressure compared to the displacement-based PFEM *** experiments demonstrate that the N-PFEM efficiently captures both transient and long-term hydro-mechanical behaviour of saturated soils with high accuracy,obviating the need for stabilisation or regularisation techniques commonly employed in other nodal integration-based PFEM *** work holds significant implications for the development of robust and accurate numerical tools for studying saturated soil dynamics.

关键词： Particle finite element method Nodal integration Dynamic saturated media Second-order cone programming(SOCP)

An unprecedented synthesis of axially chiral biaryls by rearrangement and aromatization of carbocations with central-to-axial conversion of chirality

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第9期67卷 2998-3003页

作者： Qi Liu xue-Dong Li liang Cheng Li Liu Beijing National Laboratory for Molecular Sciences(BNLMS) CAS Key Laboratory of Molecular Recognition and FunctionCAS Research/Education Center for Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

The central-to-axial chirality conversion represents a fascinating class of chemical processes consisting of the destruction of stereogenic centers and the simultaneous installation of axial chiral elements,which provides efficient methods for the preparation of axially chiral ***,developing catalytic asymmetric approaches for constructing these central chirality precursors and the efficient central-to-axial chirality conversion remains a challenge due to the requirement of aromatization or elimination *** this work,we have developed an unprecedented enantioselective intramolecular FriedelCrafts alkylation with unactivated-ketone carbonyls from which a chiral tertiary alcohol was generated with high efficiency and excellent *** addition,the central-to-axial chirality conversion strategy has been successfully applied to the synthesis of enantioenriched biaryls via a less-explored carbocation-initiated rearrangement and aromatization under the promotion of Lewis *** methodology provided a straightforward and sustainable access to a broad range of biaryl-2-carboxylic acid and in excellent yields(up to 92%)and excellent central-to-axial chirality conversion(up to 99%conversion percentage).This work could be a great model for developing new methods for synthesizing axially chiral biaryls and a general protocol for the rearrangement and aromatization of carbocations for further functionalization.

关键词： br?nsted acid catalysis desymmetrization phosphoric acid axially chiral biaryls central-to-axial conversion