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Impact of volcanism on the formation and hydrocarbon generation of organic-rich shale in the Jiyang Depression, Bohai Bay Basin, China

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Petroleum Science 2024年第3期21卷 1539-1551页

作者： Jia-Hong Gao Xin-Ping Liang Zhi-jun Jin Quan-You Liu Chang-rong Li Xiao-Wei Huang ju-Ye Shi Peng Li State Key Laboratory of Shale Oil and Gas Enrichment Mechanisms and Efficient Development Institute of EnergyPeking University Petroleum Exploration and Production Research Institute SINOPECBeijing100871 China School of Energy Resources China University of Geosciences Beijing100083 China

Globally,most organic-rich shales are deposited with volcanic ash *** ash,a source for many sedimentary basins,can affect the sedimentary water environment,alter the primary productivity,and preserve the organic matter(OM)through physical,chemical,and biological *** an increasing number of breakthroughs in shale oil exploration in the Bohai Bay Basin in recent years,less attention has been paid to the crucial role of volcanic impact especially its influence on the OM enrichment and hydrocarbon ***,we studied the petrology,mineralogy,and geochemical characteristics of the organic-rich shale in the upper submember of the fourth member(Es_(4)^(1))and the lower submember of the third member(Es_(3)^(3))of the Shahejie Formation,aiming to better understand the volcanic impact on organic-rich shale *** results show that total organic carbon is higher in the upper shale intervals rich in volcanic ash with enriched light rare earth elements and moderate Eu *** indicates that volcanism promoted OM formation before or after the *** positive correlation between Eu/Eu*and Post-Archean Australian Shale indicates hydrothermal activity before the volcanic *** plane graph of the hydrocarbon-generating intensity(S1+S2)suggests that the heat released by volcanism promoted hydrocarbon ***,the nutrients carried by volcanic ash promoted biological blooms during Es_(4)^(1 )and Es_(3)^(3) deposition,yielding a high primary *** blooms consume large amounts of oxygen and form anoxic environments conducive to the burial and preservation of ***,this study helps to further understand the organic-inorganic interactions caused by typical geological events and provides a guide for the next step of shale oil exploration and development in other lacustrine basins in China.

关键词： Volcanic ash Hydrocarbon generation Organic-rich shale Shahejie Formation Jiyang Depression

Three-dimensional interconnected graphene network-based high-performance air electrode for rechargeable zinc‒air batteries

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SusMat 2024年第3期4卷 192-203页

作者： Jia-Xing An Yu Meng Hong-Bo Zhang Yuanzhi Zhu Xiaohua Yu ju rong Peng-Xiang Hou Chang Liu Hui-Ming Cheng Jin-Cheng Li Faculty of Chemical Engineering Yunnan Provincial Key Laboratory of Energy Saving in Phosphorus Chemical Engineering and New Phosphorus MaterialsKunming University of Science and TechnologyKunmingChina Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyangChina Faculty of Materials Science and Engineering Kunming University of Science and TechnologyKunmingChina

Although zinc-air batteries(ZABs)are regarded as one of the most prospective energy storage devices,their practical application has been restricted by poor air electrode ***,we developed a free-standing air electrode that is fabricated on the basis of a multifunctional three-dimensional interconnected graphene ***,a three-dimensional interconnected graphene network with fast mass and electron transport ability,prepared by catalyzing growth of graphene foam on nickel foam and then filling reduced graphene oxide into the pores of graphene foam,is used to anchor iron phthalocyanine molecules with atomic Fe-N_(4)sites for boosting the oxygen reduction during discharging and nanosized FeNi hydroxides for accelerating the oxygen evolution during *** a result,the obtained air electrode exhibited an ultra-small electrocatalytic overpotential of 0.603 V for oxygen reactions,a high peak power density of 220.2mWcm^(-2),and a small and stable charge-discharge voltage gap of 0.70 V at 10mA cm^(-2)after 1136 ***,in situ Raman spectroscopy together with theoretical calculations confirmed that phase transformation of FeNi hydroxides takes place fromα-Ni(OH)_(x)toβ-Ni(OH)_(x)toγ-Ni^((3+δ)+)OOH for the oxygen evolution reaction and Ni is the active center while Fe enhances the activity of Ni active sites.

关键词： in situ Raman interconnected graphene network iron phthalocyanine NiFe hydroxide zinc‒air battery

Global status and trends of metabolomics in diabetes: A literature visualization knowledge graph study

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World Journal of Diabetes 2024年第5期15卷 1021-1044页

作者： Hong Li Liu Li Qiu-Qing Huang Si-Yao Yang jun-ju Zou Fan Xiao Qin Xiang Xiu Liu rong Yu College of Chinese Medicine Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina College of International Education Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina Department of Science and Technology Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina Hunan Key Laboratory of TCM Prescription and Syndromes Translational Medicine Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina College of Graduate Hunan University of Chinese MedicineHunan ChangshaHunan ProvinceChina

BACKGROUND Diabetes is a metabolic disease characterized by hyperglycemia,which has increased the global medical burden and is also the main cause of death in most *** To understand the knowledge structure of global development status,research focus,and future trend of the relationship between diabetes and metabolomics in the past 20 *** The articles about the relationship between diabetes and metabolomics in the Web of Science Core Collection were retrieved from 2002 to October 23,2023,and the relevant information was analyzed using CiteSpace6.2.2R(CiteSpace),VOSviewer6.1.18(VOSviewer),and Bibliometrix software under R *** A total of 312. publications were included from 2002 to *** the past two decades,the number of publications and citations in this field has continued to *** United States,China,Germany,the United Kingdom,and other relevant funds,institutions,and authors have significantly contributed to this *** Reports and PLoS One are the journals with the most publications and the most *** keyword co-occurrence and cluster analysis,the closely related keywords are"insulin resistance","risk","obesity","oxidative stress","metabolomics","metabolites"and"biomarkers".Keyword clustering included cardiovascular disease,gut microbiota,metabonomics,diabetic nephropathy,molecular docking,gestational diabetes mellitus,oxidative stress,and insulin *** detection analysis of keyword depicted that"Gene","microbiota","validation","kidney disease","antioxidant activity","untargeted metabolomics","management",and"accumulation"are knowledge frontiers in recent *** The relationship between metabolomics and diabetes is receiving extensive *** nephropathy,diabetic cardiovascular disease,and kidney disease are key diseases for future research in this *** microbiota,molecular docking,and untargeted metabolomics are key research directions in the *** a

关键词： Diabetes Metabolomics Bibliometric CiteSpace VOSviewer

Acute severe hypokalemia caused by treatment of tongue squamous cell carcinoma with docetaxel and cisplatin:A case report

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World Journal of Clinical Oncology 2024年第10期15卷 1309-1314页

作者： Hong-Mei Jiang rong Sun Bing-Jie Ning Xue-Qin Yang Xiao-ju Zhu Department of Cancer Center Daping HospitalArmy Medical UniversityChongqing 400042China

BACKGROUND The tongue squamous cell carcinoma(TSCC)is an oral malignant tumor arising from the squamous epithelium of the tongue mucosa,characterized by a high malignant degree,invasive growth,early lymph node metastasis,and poor ***,represented by docetaxel,is now the standard first-line treatment for head and neck squamous cell ***,which belongs to the class of drugs known as paclitaxel,is an antitumor drug that inhibits cell mitosis and *** adverse effects include myelosuppression,hair loss,gastrointestinal reactions,fluid retention,and allergic ***,hypokalemia is rare,most cases are mild or moderate,and severe hypokalemia is seldom *** of adverse effects *** is necessary to be considerate regarding individual differences between patients when selecting chemotherapy regimens and adhere to the principle of individualized *** multiple cycles of chemotherapy,patients should be aware of the accumulation of toxic side effects and receive blood tests reviewed within 24 hours of *** is essential to monitor electrolyte levels in patients suffering from severe gastrointestinal reactions to avoid complications that may result in death.

关键词： Tongue squamous cell carcinoma Docetaxel Hypokalemia Hypomagnesemia Case report

The Clumpy Structure of Five Star-bursting Dwarf Galaxies in the MaNGA Survey

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Research in Astronomy and Astrophysics 2024年第2期24卷 83-103页

作者： Mengting ju jun Yin Lei Hao Chenxu Liu Chao-Wei Tsai junfeng Wang Zhengyi Shao Shuai Feng Yu rong Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China University of Chinese Academy of Sciences Beijing 100049China Key Lab for Astrophysics Shanghai 200034China South-Western Institute for Astronomy Research Yunnan UniversityKunming 650500China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China Department of Astronomy Physics BuildingXiamen UniversityXiamenFujian 361005China College of Physics Hebei Normal UniversityShijiazhuang 050024China Hebei Key Laboratory of Photophysics Research and Application Shijiazhuang 050024China Department of Astronomy University of Science and Technology of ChinaHefei 230026China

The star-forming clumps in star-bursting dwarf galaxies provide valuable insights into understanding the evolution of dwarf *** this paper,we focus on five star-bursting dwarf galaxies featuring off-centered clumps in the Mapping Nearby Galaxies at Apache Point Observatory *** the stellar population synthesis software Fitting Analysis using Differential evolution Optimization,we obtain the spatially resolved distribution of the star formation history,which allows us to construct the g-band images of the five galaxies at different *** images can help us to probe the evolution of the morphological structures of these *** images of a stellar population older than 1 Gyr are typically smooth,images of a stellar population younger than 1 Gyr reveal significant clumps,including multiple clumps which appear at different locations and even different *** study the evolutionary connections of these five galaxies to other dwarf galaxies before their star-forming clumps appear,we construct the images of the stellar populations older than three age nodes,and define them to be the images of the"host"*** find that the properties such as the central surface brightness and the effective radii of the hosts of the five galaxies are in between those of dwarf ellipticals(dEs)and dwarf irregulars(dIrrs),with two clearly more similar to dEs and one more similar to *** the five galaxies,8257-3704 is particularly interesting,as it shows a previous starburst event that is not quite visible from its gri image,but only visible from images of the stellar population at a few hundred million *** star-forming clump associated with this event may have appeared at around 600 Myr ago and disappeared at around 40 Myr ago.

关键词： galaxies dwarf-galaxies evolution-galaxies formation-Galaxy structure

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碳金融赋能碳中和的机制与实现路径

中南民族大学学报（人文社会科学版） 2024年第7期44卷 134-144,186,187页

作者：鞠荣华刘嘉浩中国农业大学经济管理学院/中国期货与金融衍生品研究中心北京100083

在应对全球气候变化和推动经济高质量发展的背景下,碳金融作为连接经济与环境保护的重要桥梁,对于实现碳中和目标具有至关重要的作用。然而,在推进碳金融发展的过程中仍存在一系列的困难和挑战,如碳汇未能充分纳入碳金融体系,碳金融交... 详细信息

在应对全球气候变化和推动经济高质量发展的背景下,碳金融作为连接经济与环境保护的重要桥梁,对于实现碳中和目标具有至关重要的作用。然而,在推进碳金融发展的过程中仍存在一系列的困难和挑战,如碳汇未能充分纳入碳金融体系,碳金融交易机制不完善等,需要从机制和路径层面对发展我国碳金融进行研究和设计。首先,将实施碳税、碳关税及界定碳汇所有权作为激活碳汇交易的顶层设计;其次,构建支持碳中和的新型金融机制,形成碳汇投资者、碳保险、碳信贷之间的三元稳态关系;最后,打造新型碳中和智能化数字交易平台,为碳金融市场提供高效、透明、安全的交易环境。

关键词：碳中和碳金融碳汇碳关税数字金融

A novel bellidifolin intervention mitigates nonalcoholic fatty liver disease-like changes induced by bisphenol F

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Journal of Biomedical Research 2024年第5期38卷 451-463页

作者： Jing Xue Linwei Zhang Jingxian Tao Xuexue Xie Xi Wang Linlin Wu Shuhu Du Ninghua Tan Yang Jin Jianming ju junting Fan jun Wang Fei Huan rong Gao Key Laboratory of Modern Toxicology Ministry of EducationDepartment of ToxicologySchool of Public HealthNanjing Medical UniversityNanjingJiangsu 211166China Taizhou Center for Disease Control and Prevention TaizhouJiangsu 225300China Wuxi Center for Disease Control and Prevention WuxiJiangsu 214023China School of Pharmacy Jiangsu Province Engineering Research Center of Antibody DrugNanjing Medical UniversityNanjingJiangsu 211166China School of Traditional Chinese Pharmacy China Pharmaceutical UniversityNanjingJiangsu 211198China Department of Pharmaceutical Analysis School of PharmacyNanjing Medical UniversityNanjingJiangsu 211166China Laboratory of Quality and Metabolomics of Traditional Chinese Medicine Affiliated Hospital of Integrated Traditional Chinese and Western MedicineNanjing University of Chinese MedicineNanjingJiangsu 210028China Department of Hygienic Analysis and Detection Key Laboratory of Modern ToxicologyMinistry of EducationSchool of Public HealthNanjing Medical UniversityNanjingJiangsu 211166China

As a potential endocrine-disrupting chemical,bisphenol F(BPF)may cause nonalcoholic fatty liver disease(NAFLD)-like changes,but the mechanisms under its pathogenesis as well as the intervention strategies remain *** the electron microscopy technology,along with LipidTOX Deep Red neutral and Bodipy 493/503 staining assays,we observed that BPF treatment elicited a striking accumulation of lipid droplets in HepG2 cells,accompanied by an increased total level of *** the molecular level,the lipogenesis-associated mRNAs and proteins,including acetyl-CoA carboxylase,fatty acid synthase,stearoyl-CoA desaturase-1,peroxisome proliferator-activated receptor gamma,and CCAAT-enhancer-binding proteins,increased significantly via the AMP-activated protein kinase(AMPK)-mammalian target of rapamycin(mTOR)signaling regulation in both in vitro and in vivo ***,the immunofluorescence results also showed the robust lipogenesis induced by BPF,evident in its ability to promote the translocation of sterol regulatory element-binding protein-1c from the cytoplasm to the *** investigate the intervention strategies for BPF-induced NAFLD-like changes,we demonstrated that bellidifolin,isolated and purified from Swertia chirayita,significantly attenuated BPF-induced lipid droplet deposition in HepG2 cells and NAFLD-like changes in mice by blocking the expression of lipogenesis-associated ***,the present study elucidates the mechanisms underlying the BPF-induced lipid accumulation in HepG2 cells,while also highlighting the potential of bellidifolin to mitigate BPF-induced NAFLD-like changes.

关键词： bisphenol F lipogenesis non-alcoholic fatty liver disease bellidifolin

PCOS患者妊娠期过量睾酮影响男性子代生殖发育的机制研究进展

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中华生殖与避孕杂志 2024年第5期44卷 541-547页

作者：连超周宇居蓉陈建泉南京医科大学附属江宁医院中心实验室南京210000 南京医科大学附属江宁医院妇产科南京210000

多囊卵巢综合征患者典型特征之一是体内高雄激素分泌。其妊娠期母体过量睾酮水平不仅影响女性后代生殖健康,也影响男性后代生殖健康。本文主要针对PCOS患者妊娠期母源性睾酮暴露影响男性胎儿生殖发育及精子发生的机制进行综述,为妊娠期... 详细信息

多囊卵巢综合征患者典型特征之一是体内高雄激素分泌。其妊娠期母体过量睾酮水平不仅影响女性后代生殖健康,也影响男性后代生殖健康。本文主要针对PCOS患者妊娠期母源性睾酮暴露影响男性胎儿生殖发育及精子发生的机制进行综述,为妊娠期高雄激素影响男性后代生殖健康的机制研究与临床干预提供参考。

关键词：睾酮精子发生多囊卵巢综合征 cAMP反应元件结合蛋白

A multicenter prospective study on the management of hepatoblastoma in children:a report from the Chinese Children's Cancer Group

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World Journal of Pediatrics 2024年第6期20卷 590-601页

作者： Meng-Jie Tang Xiao-Li Ma Xiang-Ling He Wei-Hua Pan Xiao-Hong Zhang Sha-Yi Jiang ju Gao Fu Li Wei Yao Song Gu Wei-Ling Zhang Qiang Zhao Shi-Hao Huang Yong-jun Fang Wei Liu Hui-Zhong Niu Chun-Mei Wang Li-rong Sun Hui Gao Yun-Peng Dai Shun-Gen Huang Zhi-Yong Zhong Xi-Ge Wang Zhong-rong Li Liang-Chun Yang Ye-Ming Wu Huan-Min Wang Xin Sun Xiao-jun Yuan Department of Pediatric Hematology/Oncology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineNo.1665Kongjiang RoadYangpu DistrictShanghai 200092China Medical Oncology Department Pediatric Oncology CenterBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of Hematology/Oncology Children's Medical CenterHunan Provincial People's HospitalThe First Affiliated Hospital of Hunan Normal UniversityChangsha 41005China Department of Pediatric Surgery Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Hematology/Oncology Guangzhou Women and Children's Medical CenterNational Children's Medical Center for South Central RegionGuangzhou 510623China Department of Hematology Shanghai Children's HospitalShanghai Jiao Tong UniversityShanghai 200062China Department of Pediatrics West China Second University HospitalSichuan UniversityChengdu 610041China Department of Hematology/Oncology Qilu Children's Hospital of Shandong UniversityJinan 250022China Department of Pediatric Surgery Children's Hospital of Fudan UniversityShanghai 201102China Department of General Surgery Shanghai Children's Medical Center(National Children's Medical Center-Shanghai)Shanghai Jiao Tong University School of MedicineShanghai 200127China Department of Pediatrics Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Department of Pediatric Oncology Tianjin Medical University Cancer Institute and HospitalTianjin 300060China Department of Hematology/Oncology Children's Hospital of Nanjing Medical UniversityNanjing 210008China Department of Hematology/Oncology Henan Children's HospitalZhengzhou 450018China Department of Pediatric General Surgery Hebei Children's Hospital of Hebei Medical UniversityShijiazhuang City 050031China Children's Hospital the First Affliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of Paediatric

Background This study aimed to identify survival risk factors in Chinese children with hepatoblastoma(HB)and assess the effectiveness of the new treatment protocol proposed by the Chinese Children's Cancer Group(CCCG)in *** A multicenter,prospective study that included 399 patients with HB from January 2015 to june 2020 was *** demographics,treatment protocols,and other related information were *** regression models and Kaplan-Meier curve methods were *** The 4-year event-free survival(EFS)and overall survival(OS)were 76.9 and 93.5%,*** 4-year EFS rates for the very-low-risk,low-risk,intermediate-risk,and high-risk groups were 100%,91.6%,81.7%,and 51.0%,*** 4-year 0S was 100%,97.3%,94.4%,and 86.8%,*** regression analysis found that age,tumor rupture(R+),and extrahepatic tumor extension(E+)were independent prognostic factors.A total of 299 patients had complete remission,and 19 *** with declining alpha-fetoprotein(AFP)>75%after the first two cycles of neoadjuvant chemotherapy had a better EFS and OS than those≤75%.Conclusions The survival outcome of HB children has dramatically improved since the implementation of CCCG-HB-2016 ***≥8 years,R+,and E+were independent risk factors for *** with a declining AFP>75%after the first two cycles of neoadjuvant chemotherapy had better EFS and OS.

关键词： Alpha-fetoprotein Hepatoblastoma Multicenter Prospective study Survival