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CT whole lung radiomic nomogram:a potential biomarker for lung function evaluation and identification of COPD

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Military Medical Research 2025年第1期12卷 36-47页

作者： Tao-Hu Zhou Xiu-Xiu Zhou Jiong Ni Yan-Qing Ma fang-Yi Xu Bing Fan Yu Guan Xin-Ang Jiang Xiao-Qing Lin Jie Li Yi Xia Xiang Wang Yun Wang Wen-Jun Huang Wen-Ting Tu Peng Dong Zhao-Bin Li shi-Yuan Liu Li Fan Department of Radiology the Second Affiliated Hospital of Naval Medical UniversityShanghai 200003China School of Medical Imaging Shandong Second Medical UniversityWeifang 261053ShandongChina Department of Radiology School of MedicineTongji HospitalTongji UniversityShanghai 200065China Department of Radiology Zhejiang Province People’s HospitalAffiliated People’s Hospital of Hangzhou Medical CollegeHangzhou 310014China Department of Radiology Sir Run Run Shaw HospitalZhejiang 310018China Jiangxi Provincial People’s Hospital the First Affiliated Hospital of Nanchang Medical CollegeNanchang 330006China College of Health Sciences and Engineering University of Shanghai for Science and TechnologyShanghai 200093China Department of Radiology the Second People’s Hospital of DeyangDeyang 618000SichuanChina Department of Radiation Oncology Shanghai Jiao Tong University Affiliated Sixth People’s HospitalShanghai 200233China

Background:Computed tomography(CT)plays a great role in characterizing and quantifying changes in lung structure and function of chronic obstructive pulmonary disease(COPD).This study aimed to explore the performance of CT-based whole lung radiomic in discriminating COPD patients and non-COPD ***:This retrospective study was performed on 2785 patients who underwent pulmonary function examination in 5 hospitals and were divided into non-COPD group and COPD *** radiomic features of the whole lung volume were *** absolute shrinkage and selection operator(LASSO)logistic regression was applied for feature selection and radiomic signature construction.A radiomic nomogram was established by combining the radiomic score and clinical *** operating characteristic(ROC)curve analysis and decision curve analysis(DCA)were used to evaluate the predictive performance of the radiomic nomogram in the training,internal validation,and independent external validation ***:Eighteen radiomic features were collected from the whole lung volume to construct a radiomic *** area under the curve(AUC)of the radiomic model in the training,internal,and independent external validation cohorts were 0.888[95%confidence interval(CI)0.869–0.906],0.874(95%CI 0.844–0.904),and 0.846(95%CI 0.822–0.870),*** were higher than the clinical model(AUC were 0.732,0.714,and 0.777,respectively,P<0.001).DCA demonstrated that the nomogram constructed by combining radiomic score,age,sex,height,and smoking status was superior to the clinical factor ***:The intuitive nomogram constructed by CT-based whole-lung radiomic has shown good performance and high accuracy in identifying COPD in this multicenter study.

关键词： Chronic obstructive pulmonary disease(COPD) Computed tomography(CT) Radiomic

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金刚石膜的制备和高取向生长

炭素技术 2002年第1期21卷 34-41页

作者：孙超汪爱英黄荣芳闻立时中国科学院金属研究所辽宁沈阳110016

金刚石膜是最近世界上研究最广泛的材料之一。在本文中 ,简要介绍了低压化学气相沉积金刚石薄膜的合成技术及高取向生长。

关键词：低压化学气相沉积金刚石膜合成技术高取向生长

凉膈散加减方治疗脓毒症致急性胃肠损伤的临床观察

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中国中医急症 2025年第1期34卷 120-124页

作者：金岳施荣上海中医药大学附属曙光医院上海201203

目的观察凉膈散加减方治疗脓毒症致急性胃肠损伤(AGI)患者的临床疗效。方法将82例患者随机分为治疗组与对照组各41例,两组患者均予指南常规治疗,治疗组加予凉膈散加减方,疗程7 d。治疗后,观察两组主要疗效指标(AGI分级),次要疗效指标... 详细信息

目的观察凉膈散加减方治疗脓毒症致急性胃肠损伤(AGI)患者的临床疗效。方法将82例患者随机分为治疗组与对照组各41例,两组患者均予指南常规治疗,治疗组加予凉膈散加减方,疗程7 d。治疗后,观察两组主要疗效指标(AGI分级),次要疗效指标[中医临床疗效、急性生理与慢性健康状况Ⅱ(APACHE Ⅱ)评分、序贯器官衰竭量表(SOFA)评分、腹围、腹内压、肠鸣音],以及D-乳酸、二胺氧化酶(DAO)、细菌内毒素、白细胞计数(WBC)、C反应蛋白(CRP)、降钙素原(PCT)、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)水平。结果治疗组AGI分级改善程度显著优于对照组(P<0.05);治疗组中医临床显效率为82.93%,显著高于对照组的46.34%(P<0.05);治疗组APACHE Ⅱ评分、SOFA评分、腹围、腹内压均低于对照组(P<0.05);治疗后肠鸣音次数显著增加(P<0.05);治疗组血清D-乳酸、DAO及细菌内毒素水平显著降低(P<0.05);治疗组WBC、CRP、PCT、TNF-α、IL-6水平均低于对照组(P<0.05)。结论凉膈散加减方能显著改善脓毒症AGI患者胃肠功能,减轻炎症反应,提高中医临床疗效。

关键词：脓毒症急性胃肠损伤胃肠功能凉膈散加减方炎症因子

FeMnCoNi-O活化过硫酸氢钾降解罗丹明B

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中国环境科学 2025年第2期45卷 759-767页

作者：徐邦利严海线翁诗雅王世琦方峰东南大学材料科学与工程学院江苏南京211189

以乙酸盐和柠檬酸钠为原料,通过共沉淀-热处理法合成了结构稳定且性能优良的FeMnCoNi-O纳米颗粒,使用XRD,TEM,FT-IR,TG,ICP,XPS等手段对其进行表征,并将其应用于常温常压下活化过硫酸氢钾(PMS)降解罗丹明B(RhB),探究PMS浓度､RhB浓度､污... 详细信息

以乙酸盐和柠檬酸钠为原料,通过共沉淀-热处理法合成了结构稳定且性能优良的FeMnCoNi-O纳米颗粒,使用XRD,TEM,FT-IR,TG,ICP,XPS等手段对其进行表征,并将其应用于常温常压下活化过硫酸氢钾(PMS)降解罗丹明B(RhB),探究PMS浓度､RhB浓度､污染物种类､FeMnCoNi-O浓度､初始pH值､水中阴离子种类等反应条件对降解效果的影响,以及FeMnCoNi-O纳米颗粒的循环使用性能.结果表明,经过200℃保温2h后样品从普鲁士蓝类似物转变为多元金属氧化物,活化PMS降解RhB能力显著提高.FeMnCoNi-O纳米颗粒可以通过活化微量的PMS(0.2mmol/L),在10min内实现RhB(20mg/L)的完全降解.自由基淬灭和XPS结果表明,体系中主要活性物质为过硫酸氢根活化生成的^(1)O_(2)和SO_(4)^(·-).

关键词：污水处理高级氧化多元金属氧化物 PMS活化罗丹明B降解

基于PMI泡沫的可重复使用结构隔声性能研究

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振动与冲击 2025年第2期44卷 344-350页

作者：秦朝红侯传涛康军魏龙荣克林郝子元任方北京强度环境研究所可靠性与环境工程技术重点实验室北京100076 北京宇航系统工程研究所北京100076

可重复飞行器飞行过程中,面临着复杂的力、热、空间等载荷环境,对飞行器系统可靠性和结构完整性提出了需求。可重复飞行器上升、再入过程中受到严酷的气动噪声环境,噪声传到飞行器内,会对内部的设备产生影响。因此在对结构进行设计时,... 详细信息

可重复飞行器飞行过程中,面临着复杂的力、热、空间等载荷环境,对飞行器系统可靠性和结构完整性提出了需求。可重复飞行器上升、再入过程中受到严酷的气动噪声环境,噪声传到飞行器内,会对内部的设备产生影响。因此在对结构进行设计时,除了轻质、承载、耐温等设计要求外,还要达到很好的隔声性能,在轨期间满足一定的空间环境要求,并可实现可重复使用。考虑到聚甲基丙烯酰亚胺(polymethacrylimide, PMI)泡沫优异的耐热性、比强度高、轻质等特点,将PMI泡沫与复合材料蜂窝板进行复合,开展其隔声性能研究,获取了典型试验件的隔声性能。在此基础上对飞行器结构进行了设计,通过试验验证了其良好的隔声效果。开展了不同剂量的带电粒子辐照试验,对其多次、长期在轨后的隔声性能进行了评估,在30~5 000 krad(Si)粒子辐照下,不管是PMI泡沫还是PMI泡沫与蜂窝复合结构的隔声性能变化不大,满足可重复使用的隔声性能要求。

关键词：可重复使用结构隔声性能空间环境聚甲基丙烯酰亚胺(PMI)泡沫蜂窝结构

用户画像在老年慢性病患者健康管理中应用的范围综述

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中华护理杂志 2025年第2期60卷 244-250页

作者：施艳鸿颜缘娇林榕黄晨杉李红福建医科大学护理学院福州市350004 福建省立医院护理部

目的对用户画像在老年慢性病患者健康管理中应用的相关研究进行范围综述,为老年慢性病患者的健康管理提供参考。方法按照范围综述方法学,系统检索万方数据库、中国知网、维普数据库、中国生物医学文献服务系统、PubMed、Embase、Web of ... 详细信息

目的对用户画像在老年慢性病患者健康管理中应用的相关研究进行范围综述,为老年慢性病患者的健康管理提供参考。方法按照范围综述方法学,系统检索万方数据库、中国知网、维普数据库、中国生物医学文献服务系统、PubMed、Embase、Web of Science、CINAHL、Cochrane Library共9个数据库,检索时限为建库至2024年1月,根据纳入和排除标准筛选文献,由2名研究者独立提取并归纳文献中的信息。结果共纳入10篇文献。构建用户画像的过程主要包括数据采集、用户特征提取及画像生成与可视化。用户画像在老年慢性病健康管理中应用范围较为广泛,常用于糖尿病、心力衰竭等老年慢性病患者的健康管理,包括制订个性化干预计划、提供个性化健康教育和信息、调整健康管理策略等内容。在老年慢性病患者中应用用户画像,可提升健康信息传递和健康服务的精准度、优化用户使用体验、提高老年慢性病患者自我管理能力和生活质量,优化医疗服务的可及性。结论用户画像作为一种新兴的健康信息整合手段,可以分析多维度的健康数据,为老年慢性病患者提供个性化、精准的健康管理,改善健康管理效果,降低医疗成本,提高其满意度和参与度,在老年慢性病患者健康管理中具有较好的应用前景。

关键词：用户画像慢性病老年人范围综述健康管理护理

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维生素C调控合成纯球霰石及其形成机理

硅酸盐通报 2025年第1期44卷 195-201,242页

作者：吴广武白蓉方虎赵成陈佩圆安徽理工大学土木建筑学院淮南232001 中国建筑第四工程局有限公司广州510665 安徽理工大学深部煤矿采动响应与灾害防控国家重点实验室淮南232001

为建立一种以氯化钙为原料合成高纯度球霰石型碳酸钙并封存CO_(2)的工艺,本文采用氯化钙为钙源,使用CO_(2)碳化法,维生素C为晶型调控剂调控合成球霰石。利用X射线衍射仪、傅里叶变换红外光谱仪、扫描电子显微镜等对产物进行表征,研究不... 详细信息

为建立一种以氯化钙为原料合成高纯度球霰石型碳酸钙并封存CO_(2)的工艺,本文采用氯化钙为钙源,使用CO_(2)碳化法,维生素C为晶型调控剂调控合成球霰石。利用X射线衍射仪、傅里叶变换红外光谱仪、扫描电子显微镜等对产物进行表征,研究不同维生素C浓度对制备碳酸钙晶型和形貌的影响,并探讨在维生素C调控下球霰石可能的形成机理。结果表明:维生素C对稳定球霰石多晶型的效果显著,未加入维生素C时,产物为球霰石与方解石的混合物,添加质量分数0.1%的维生素C即可得到纯度为100%的球霰石。此外,随着维生素C浓度增加,碳酸钙比表面积由3.63 m^(2)/g提高到11.62 m^(2)/g,晶体粒径由1~3μm减小到0.3~0.6μm。本研究提供了一种简便、绿色、低成本制备纯球霰石的方法,同时可以安全有效地封存CO_(2)温室气体。

关键词：球霰石维生素C 碳酸钙二氧化碳晶型调控剂

Effects of propofol combined with lidocaine on hemodynamics, serum adrenocorticotropic hormone, interleukin-6, and cortisol in children

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World Journal of Clinical Cases 2022年第24期10卷 8506-8513页

作者： Song shi Lu Gan Chun-Nv Jin rong-fang Liu Department of Anesthesiology Affiliated Hospital of Hebei UniversityBaoding 071000Hebei ProvinceChina Department of Anesthesiology Baoding Maternal and Child Health HospitalBaoding 071000Hebei ProvinceChina

BACKGROUND Children are a unique patient *** for pediatric abdominal surgery has long been achieved mainly with intravenous amiodarone and propofol alone or combined with other *** incidence of complications and postoperative adverse reactions is relatively high owing to the imperfect development of various protocols for *** the most appropriate anesthesia program is an important means of reducing adverse *** To explore the clinical value of propofol combined with lidocaine-assisted anesthesia in pediatric *** A total of 120 children who underwent abdominal surgery at our hospital from January 2016 to March 2018 were selected and divided into groups A and B using the random number table method,with 60 patients in each *** B received ketamine for anesthesia,while group A received ketamine,propofol,and *** pre-and postoperative heart rate(HR);mean arterial pressure(MAP);arterial oxygen saturation(SpO_(2));serum adrenocorticotropic hormone(ACTH),interleukin-6(IL-6),and cortisol(Cor)levels;restlessness score during the recovery period[Paediatric Anesthesia Emergence Delirium Scale(PAED)];and adverse reactions were compared between the two *** The HR,MAP,and SpO_(2) Level at five minutes before initiating anesthesia were compared between groups A and B,and the difference was not statistically significant(P>0.05).At 10 and 20 minutes after anesthesia initiation,the HR and MAP were lower in group A compared with group B(P0.05);however,the postoperative serum ACTH,IL-6,and Cor levels in group A were lower compared with group B(P<0.05).Furthermore,the visual analog scale scores of group A at 2 h and 8 h postoperative were lower than those in group B,and the differences were statistically significant(P<0.05).The mean PAED score in group A was lower than t

关键词： Ketamine Propofol Lidocaine Anesthesia Children

The abundance of massive compact galaxies at 1.0

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Research in Astronomy and Astrophysics 2019年第10期19卷 109-120页

作者： shi-Ying Lu Yi-Zhou Gu Guan-Wen fang Qi-rong Yuan Department of Physics and Institute of Theoretical Physics Nanjing Normal University Nanjing 210023 China Institute for Astronomy and History of Science and Technology Dali UniversityDali 671003 China

Based on a large sample of massive(M* 1010 M⊙) compact galaxies at 1.0 < z < 3.0 in five 3 D-HST/CANDELS fields, we quantify the fractional abundance and comoving number density of massive compact galaxies as a funct... 详细信息

Based on a large sample of massive(M* 1010 M⊙) compact galaxies at 1.0 shift. The samples of compact quiescent galaxies(cQGs) and compact star-forming galaxies(cSFGs) are constructed by various selection criteria of compact galaxies in the literature, and the effect of compactness definition on abundance estimate has proven to be remarkable,particularly for the cQGs and cSFGs at high redshifts. Regardless of the compactness criteria adopted,their overall redshift evolutions of fractional abundance and number density are found to be rather *** samples of the cQGs exhibit a sustained increase in number density from z ~ 3 to 2 and a plateau at 1 shifts(z < 1) can be interpreted by the decrease of gas reservoirs in dark matter halos and the consequent low efficiency of gas-rich dissipation.

关键词： galaxies high-redshift-galaxies massive-compact-galaxies evolution-galaxies