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血行播散性肺结核和矽肺结节CT扫描征象的量化分析

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结核病与肺部健康杂志 2016年第4期5卷 316-320页

作者：刘荣荣吴妹英闵春燕李敏苏州市第五人民医院放射科 215007 苏州市第五人民医院肺科 215007 苏州市第五人民医院职业病科 215007

目的通过量化分布差异的方法研究血行播散性肺结核和矽肺结节的CT扫描征象,为提高诊断准确率提供又一途径.方法回顾性分析2013年10月至2016年5月苏州市第五人民医院收治的105例确诊为血行播散性肺结核（简称“血播组”）和248例矽肺... 详细信息

目的通过量化分布差异的方法研究血行播散性肺结核和矽肺结节的CT扫描征象,为提高诊断准确率提供又一途径.方法回顾性分析2013年10月至2016年5月苏州市第五人民医院收治的105例确诊为血行播散性肺结核（简称“血播组”）和248例矽肺（简称“矽肺组”）患者的CT影像学资料,按照数字表法随机从两组中各抽取30例患者作为研究对象.对两组结节主观判断直径大小、密度高低、分布部位是否均匀、有无优势分布区域;分别从肺部纵向和横向分区,以及对病灶在两肺不同区域的分布面积进行量化分析,计算CT图像上结节分布的面积与相应肺区总面积的比值.亚急性血行播散性肺结核的结节分布面积以所占整个肺面积的比率来表述并比较差异性;采用SPSS 19.0软件对矽肺的纵向和横向的面积分布比较采用单因素方差分析、左右肺面积分布的比较采用配对样本t检验,均以P＜0.05为差异有统计学意义.结果急性血行播散性肺结核CT影像表现为结节的“三均匀”特点（分布部位、直径大小、密度都均匀）.亚急性血行播散性肺结核和矽肺均表现为结节分布面积、大小、密度不均匀,前者纵向分布肺尖到肺底结节逐渐减少（上肺野85.14％、中肺野82.34％、下肺野79.65％）,后者上肺野（32.69％）、中肺野（32.73％）、下肺野（21.12％）分布差异有统计学意义（F=12.24,P＜0.01）;横向分布上前者外带（86.05％）最多,且胸膜下有结核结节分布6例,而后者中带（37.27％）最多,分布差异有统计学意义（F=33.40,P＜0.01）,且胸膜下无结节分布,形成胸膜下透亮带6例;前者两肺（右肺82.14％、左肺82.61％）相对对称分布,后者两肺（右肺28.71％、左肺28.99％）差异不大,两者分布差异均无统计学意义（t=-0.12,P=0.905）.结论血行播散性肺结核结节与矽肺结节在横纵向的分布、胸膜下结节的有无方面均有其各自特点,量化面积分布的方法可作为协助鉴别诊断的重要依据.

关键词：结核,肺矽肺多发性肺结节体层摄影术,螺旋计算机诊断,鉴别

UPPER BOUND FOR FINITE-TIME RUIN PROBABILITY IN A MARKOV-MODULATED MARKET

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Journal of Systems Science & Complexity 2011年第2期24卷 308-316页

作者： Jinzhu LI rong wu School of Mathematical Sciences and LPMC Nankai University Tianjin 300071 China.

This paper studies the upper bound for finite-time ruin probability of an insurance company which invests its wealth in a stock and a bond. The authors assume that the interest rate of the bond and the volatility of the stock are modulated by a continuous-time stationary Markov chain with finite state. By a pure probabilistic method, the upper bound for the finite-time ruin probability is obtained.

关键词： Finite-time ruin probability jump-diffusion model Markov-modulated process.

Commentary:Acute psychological stress redistributed leukocytes via distinct brain circuits

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Acta Pharmaceutica Sinica B 2022年第12期12卷 4522-4524页

作者： Yan-Ping wu rong-rong He Guangdong Engineering Research Center of Chinese Medicine&Disease Susceptibility Jinan UniversityGuangzhou 510632China School of Traditional Chinese Medicine Jinan UniversityGuangzhou 510632China International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education(MOE) College of PharmacyJinan UniversityGuangzhou 510632China Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research College of PharmacyJinan UniversityGuangzhou 510632China

It is commonly known that psychological stress affects immunity through the nervous system,but the specific stress networks between brain and peripheral leukocytes,or their relationship with disease initiation or progression have yet to been delineated.A recent study by Poller and his colleagues1 propose an innovative perspective that distinct brain circuits rapidly manipulate a large-scale whole-body re-distribution of leukocytes(neutrophils,monocytes,lymphocytes)during psychological stress.

关键词： Acute psychological stress Peripheral leukocytes HPA axis CXCL1

OPTIMAL RISK CONTROL POLICIES FOR DIFFUSION MODELS WITH NON-CHEAP PROPORTIONAL REINSURANCE AND BANKRUPTCY VALUE

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Journal of Systems Science & Complexity 2011年第5期24卷 892-906页

作者： Minghua wu rong wu Aimin ZHOU School of Economics Nankai University Tianjin 3（}0071 China. School of Mathematical Sciences and LPMC Nankai University Tianjin 300071 China School of Economics Nankai University Tianjin 300071 China

This paper considers the problem about optimization of proportional reinsurance in the setting of diffusion models. The authors take into account non-cheap proportional reinsurance and bankruptcy value simultaneously. The objective is to find the risk control policies which maximize the total discounted reserve and the bankruptcy value. Results show that, the optimal risk control policies and corresponding optimal return functions vary, depending both on the range of bankruptcy value and the relationship between the premium rate of insurance and that of reinsurance.

关键词： Bankruptcy value diffusion models Hamilton-Jacobi-Bellman equation proportionalreinsurance.

Examining the efficacy of revegetation practices in ecosystem restoration programs:insights from a hotspot of sandstorm in northern China

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Frontiers of Earth Science 2021年第4期15卷 922-935页

作者： Ziqiang DU rong rong Zhitao wu Hong ZHANG Institute of Loess Plateau Shanxi UniversityTaiyuan 030006China 2 Shanxi Key Laboratory for Ecological restoration of Loess Plateau Taiyuan 030006China Field Scientific Observation and Research Station of the Ministry of Education of Shanxi Subalpine Grassland Ecosystem Taiyuan 030006China College of Environmental&Resource Sciences Shanxi UniversityTaiyuan 030006China

Retrospectively evaluating the efficacy of revegetation practices is helpful in planning and imple-menting future ecosystem restoration programs(ERP).Having a good understanding of how human activities can affect vegetation cover,both before and after ERP,is particularly important in sandstorm hotspot *** Beijing-Tianjin Sandstorm Source Region(BTSSR)is one such *** conducted an investigation into vegetation dynamics within the *** was done using remote sensing data in conjunction with climate data sets and land use data spanning the 1982-2014 *** relationships between climatic factors(such as precipitation and temperature),and vegetative change were modeled using a neural network *** a process of residual analysis,the proportions of human-induced vegetative change both before and after the ERP were *** results show that:1)before the ERP(1982-2000),40.96%of the study area exhibited significantly progressive vegetation changes(p<0.05).This proportion decreased to encom-pass only 20.23%of the study area in the period following the ERP(2001-2014).2)89.55%of the study area showed signs of human-induced vegetation degradation before the *** 2001 and 2014 however,following ERP,this figure fell to only 27.78%.3)ERP implementation led to visible improvements in vegetative conditions within the BTSSR,especially in areas where ecological restoration measures were directly and anthropogenically *** results highlight the benefits that positive human action(i.e.,revegetation initiatives implemented under the framework of an ERP)have brought to the BTSSR.

关键词： vegetation dynamics human activities ERP neural network model Beijing-Tianjin sandstorm source region

Gut microbiota shifts in hepatitis B-related portal hypertension after transjugular intrahepatic portosystemic shunt:Mechanistic and clinical implications

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World Journal of Gastroenterology 2025年第3期31卷 134-137页

作者： Qi-rong Jiang Da-wu Zeng Department of Hepatology Hepatology Research InstituteThe First Affiliated HospitalFujian Medical UniversityFuzhou 350005Fujian ProvinceChina Department of Infectious Diseases The First Affiliated Hospital of Fujian Medical UniversityFuzhou 350004Fujian ProvinceChina

In this article,we provide commentary on the recent article by Zhao et *** focus on the shifts in the gut microbiota of patients with hepatitis B virus(HBV)-associated cirrhosis/portal hypertension(PH)following transjugular intrahepatic portosystemic shunt(TIPS)and the implications for understanding the mechanisms,diagnosis,and *** comparing the gut microbiota composition and dynamic changes before and after TIPS in patients with and without hepatic encephalopathy,the authors found an increase in non-probiotic bacteria in those who developed hepatic encephalopathy post-TIPS,with Morganella species present only in the hepatic encephalopathy *** gut microbiota changes post-TIPS among patients without the occurrence of hepatic encephalopathy suggest potential therapeutic benefits through prophylactic microbiome ***,the specific gut microbiota alterations may hold promise to predict the risk of hepatic encephalopathy in individuals undergoing TIPS for HBVrelated *** these promising findings,future studies are needed to address limitations,including a small sample size,a relatively short evaluation period for gut microbiota alterations,the absence of data on dynamic alterations in gut microbiota post-TIPS and their correlation with blood ammonia levels,and the lack of validation in animal *** conclusion,Zhao et al's study has shed new light on the link of gut microbiota with post-TIPS hepatic encephalopathy,potentially through the intricate gut-liver axis,and has important clinical implications for improving the management of patients with HBV-related PH.

关键词： Hepatitis B virus Cirrhosis Portal hypertension Hepatic encephalopathy Transjugular intrahepatic portosystemic shunt Gut microbiota

A Note on the Perturbed Compound Poisson Risk Model with a Threshold Dividend Strategy

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Acta Mathematicae Applicatae Sinica 2009年第2期25卷 205-216页

作者： Bo Li rong wu School of Mathematical Sciences and LPMC Nankai University Tianjin 300071 China

In this paper, we consider the Perturbed Compound Poisson Risk Model with a threshold dividend strategy （PCT）. Integro-differential equations （IDE） for its Cerber-Shiu functions and dividend payments function are ... 详细信息

关键词： Gerber-Shiu function threshold dividend strategy expected discounted payments function integro-differential equation

Differentiability of dividends function on jump-diffusion risk process with a barrier dividend strategy

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Frontiers of Mathematics in China 2014年第5期9卷 1073-1088页

作者： Yuhua LU rong wu School of Mathematics Sciences Qufu Normal University Qufu 273165 China School of Mathematics Sciences and LPMC Nankai University Tianjin 300071 China

We consider a dividends model with a stochastic jump perturbed by diffusion. First, we prove that the expected discounted dividends function is twice continuously differentiable under the condition that the claim distribution function has continuous density. Then we show that the expected discounted dividends function under a barrier strategy satisfies some integro-differential equation of defective renewal type, and the solution of which can be explicitly expressed as a convolution formula. Finally, we study the Laplace transform of ruin time on the modified surplus process.

关键词： Expected discounted dividends ruin time integro-differentialequation Laplace transform barrier strategy

Discrete DNA Three-dimensional Nanostructures： the Synthesis and Applications

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Chinese Journal of Polymer Science 2017年第1期35卷 1-1,2-24页

作者： Xiao-rong wu Chen-wei wu 张川 School of Chemistry and Chemical Engineering State Key Laboratory of Metal Matrix Composites Shanghai Key Laboratory of Electrical Insulation and Thermal Ageing Shanghai Jiao Tong University

Structural DNA nanotechnology, an emerging technique that utilizes the nucleic acid molecule as generic polymer to programmably assemble well-defined and nano-sized architectures, holds great promise for new material synthesis and constructing functional nanodevices for different purposes. In the past three decades, rapid development of this technique has enabled the syntheses of hundreds and thousands of DNA nanostructures with various morphologies at different scales and dimensions. Among them, discrete three-dimensional （3D） DNA nanostructures not only represent the most advances in new material design, but also can serve as an excellent platform for many important applications. With precise spatial addressability and capability of arbitrary control over size, shape, and function, these nanostructures have drawn particular interests to scientists in different research fields. In this review article, we will briefly summarize the development regarding the synthesis of discrete DNA 3D nanostructures with various size, shape, geometry, and topology, including our previous work and recent progress by other groups. In detail, three methods majorly used to synthesize the DNA 3D objects will be introduced accordingly. Additionally, the principle, design rule, as well as pros and cons of each method will be highlighted. As functions of these discrete 3D nanostructures have drawn great interests to researchers, we will further discuss their cutting-edge applications in different areas, ranging from novel material synthesis, new device fabrication, and biomedical applications, etc. Lastly, challenges and outlook of these promising nanostructures will be given based on our point of view.

关键词： DNA self-assembly DNA 3D nanostructure Nanocarrier Biosensor Nanomedicine