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RNAi-mediated silencing of CD147 inhibits tumor cell proliferation,invasion and increases chemosensitivity to cisplatin in SGC7901 cells in vitro

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RNAi-mediated silencing of CD147 inhibits tumor cell prolife...

Image feature optimization based on nonlinear dimensionality reduction

2010’全国肿瘤分子标志及应用学术研讨会暨第五届中国中青年肿瘤专家论坛

作者： Yong-Fei Xu~(1*),Bang-Shun HE~2,Yu-Qin PAN~2,Li-rong ZHANG~2,chan zhu~1,Li-Li Qu~2,and Shu-Kui WANG~(2§) 1 Department of Life Sciences,Nanjing Normal University,Nanjing,Jiangsu 210046,China 2 Central Laboratory of Nanjing First Hospital Affiliated to Nanjing Medical University,Nanjing, Jiangsu 210012,China

Background:CD147 is a widely distributed cell surface glycoprotein that belongs to the Ig ***147 has been implicated in numerous physiological and pathological *** on the surface of many tumor cells,CD 147 promotes

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第12期10卷 1720-1737页

作者： rong zhu Min YAO School of Computer Science and Technology Zhejiang University Hangzhou 310027 China School of lnformation Engineering Jiaxing University Jiaxing 314001 China State Key Laboratory for Novel Software Technology Nanjing University Nanjing 210093 China

Image feature optimization is an important means to deal with high-dimensional image data in image semantic understanding and its applications. We formulate image feature optimization as the establishment of a mapping between highand low-dimensional space via a five-tuple model. Nonlinear dimensionality reduction based on manifold learning provides a feasible way for solving such a problem. We propose a novel globular neighborhood based locally linear embedding (GNLLE) algorithm using neighborhood update and an incremental neighbor search scheme, which not only can handle sparse datasets but also has strong anti-noise capability and good topological stability. Given that the distance measure adopted in nonlinear dimensionality reduction is usually based on pairwise similarity calculation, we also present a globular neighborhood and path clustering based locally linear embedding (GNPCLLE) algorithm based on path-based clustering. Due to its full consideration of correlations between image data, GNPCLLE can eliminate the distortion of the overall topological structure within the dataset on the manifold. Experimental results on two image sets show the effectiveness and efficiency of the proposed algorithms.

关键词： Image feature optimization Nonlinear dimensionality reduction Manifold learning Locally linear embedding (LLE)

The Existence of Weak Solutions to the 2D Euler Equations with Initial Vorticity in BMO

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Acta Mathematica Sinica,English Series 2007年第10期23卷 1881-1888页

作者： Xiang rong zhu Department of Mathematics Zhejiang University Hangzhou 310027 P. R. China

We shall prove that there exists a weak solution to the 2D Euler equations with initial vorticity in BMO and initial velocity in L^∞.

关键词： Euler equation weak solution BMO

Jacobian-determinant Equation in the Critical Besov Spaces

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Acta Mathematica Sinica,English Series 2017年第5期33卷 691-704页

作者： Xiang rong zhu Department of Mathematics Zhejiang Normal University Jinhua 321004 P. R. China

Let Ω be a bounded domain in R;with smooth boundary. Here we consider the following Jacobian-determinant equation det u（x）=f（x）,x∈Ω;u（x）=x,x∈?Ω where f is a function on Ω with min;f = δ > 0 and Ωf（x）dx = |Ω|. We prove that if f ∈B;（Ω） for some p∈（n,∞）, then there exists a solution u ∈ B;（Ω）C;（Ω） to this equation. On the other hand, we give a simple example such that u ∈ C;（R;, R;） while detu does not lie in B;（R;） for any p<∞.

关键词： Jacobian-determinant Besov space elliptic system Neumann problem

Cretaceous Sandbody Characters at Shallow-Water Lake Delta Front and the Sedimentary Dynamic Process Analysis in Songliao Basin,China

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Acta Geologica Sinica(English Edition) 2011年第6期85卷 1478-1494页

作者： CAI Xiyuan zhu rong China Petroleum and Chemical Corporation Beijing 100029 China Department of Ocean Science andEngineering Zhejiang University Hangzhou 310028 China

Based on the abundant information from drilling, cores, and logging, the influence of topography, size of rivers and lakes, climate changes and the lake level＇s fluctuation on the sandbodies at shallow-water delta front are systematically summarized and the sedimentary dynamic processes are analyzed. The interwell communication among the sandbodies and their planar distribution revealed from the hydrodynamic features of the development wells are integrated during the analysis. The fundamental requirements for the development of the shallow-water delta included flat topography and uniform subsiding rate. The delta plain was connected smoothly with the wide delta front and predelta, without the three-fold structure of topset, foreset, and bottomset as defined in the Gilbert Delta Model. Because of the weak fluvial effect and the lake energy is strong, the small and scattered shallow-water delta is destroyed by the scouring-backwashing, coastal current, and lake wave, resulting in the coastal sheet deposition. As the fluvial effect became stronger and the lake energy became weaker, the shape of the shallow-water deltas transferred from sheets to lumps and then branches.

关键词： lake-level fluctuation shallow-water delta sedimentary dynamics,Songliao Basin China

Solar flare forecasting based on sequential sunspot data

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Research in Astronomy and Astrophysics 2013年第9期13卷 1118-1126页

作者： rong Li Jie zhu School of Information Science Beijing Wuzi University

It is widely believed that the evolution of solar active regions leads to solar flares. However, information about the evolution of solar active regions is not employed in most existing solar flare forecasting models. In the current work, a short- term solar flare forecasting model is proposed, in which sequential sunspot data, in- cluding three days of information about evolution from active regions, are taken as one of the basic predictors. The sunspot area, the Mclntosh classification, the mag- netic classification and the radio flux are extracted and converted to a numerical for- mat that is suitable for the current forecasting model. Based on these parameters, the sliding-window method is used to form the sequential data by adding three days of information about evolution. Then, multi-layer perceptron and learning vector quanti- zation are employed to predict the flare level within 48 h. Experimental results indicate that the performance of the proposed flare forecasting model works better than previ- ous models.

关键词： Sun: flares -- sunspots -- machine learning

Maximal operators of pseudo-differential operators with rough symbols

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 174-180页

作者： Ramla Benhamoud zhu Xiang-rong School of Mathematical Sciences Zhejiang Normal UniversityJinhua 321004China

Consider a pseudo-differential operator T_(a)f(x)=∫_(R^(n))e^(ix,ζ)a(x,ζ)f(ζ)dζwhere the symbol a is in the rough Hormander class L^(∞)S_(ρ)^(m)with m∈R andρ∈[0,1].In this note,when 1≤p≤2,if n(ρ-1)/p and a∈L^(∞)S_(ρ)^(m),then for any f∈S(R^(n))and x∈R^(n),we prove that M(T_(a)f)(x)≤C(M(|f|^(p))(x))^(1/p) where M is the Hardy-Littlewood maximal *** theorem improves the known results and the bound on m is sharp,in the sense that n(ρ-1)/p can not be replaced by a larger constant.

关键词： pseudo-differential operator rough Hormander class H-L maximal operator

Thermal insulation design of subsea vertical X-mas tree

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Petroleum Science 2021年第4期18卷 1182-1194页

作者： Xin rong Hong-Wu zhu College of Mechanical and Transportation Engineering China University of PetroleumBeijing102249China

Temperature drop is commonly observed in subsea vertical X-mas trees during *** presence of a huge temperature difference between internal crude oil and external seawater can cause severe equipment degradation of the oil flow channel(e.g.,hydrate precipitation),which can block the oil flow channel and interrupt the production *** most vulnerable parts of a subsea vertical X-mas tree tend to be components with high convective heat transfer rates,such as production modules and short *** proposed an innovative approach for the insulation design of underwater equipment under a shutdown ***,we obtained a heat transfer analysis of the tree under working conditions through computational fluid dynamics to ascertain the initial temperature condition for an unsteadystate ***,we investigated the unsteady heat transfer characteristics of the tree with an insulation layer in the shutdown state and derived the relationships between insulation duration and thickness by data *** used data analysis to identify the relationship between insulation duration and ***,we derived the empirical formula of insulation thickness for underwater equipment given the effect of environmental factors on the heat preservation *** performed the experiment with an oil pipeline,and the results showed that the internal oil of the equipment did not hydrate within 8 h under the shutdown condition with insulation layers.

关键词： Subsea vertical X-mas tree Thermal insulation design Unsteady heat-transfer analysis Computational fluid dynamics

Effect of methane-hydrogen mixtures on flow and combustion of coherent jets

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Journal of Iron and Steel Research International 2017年第11期24卷 1143-1151页

作者： Ting Cheng rong zhu Kai Dong School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Beijing Key Laboratory of Research Center of Special Melting and Preparation of High-end Metal Materials University of Science and Technology BeijingBeijing 100083China

Coherent jets are widely used in electric are furnace （EAF） steelmaking to increase the oxygen utilization and chemical reaction rates. However, the influence of fuel gas combustion on jet behavior is not fully understood yet. The flow and combustion characteristics of a coherent jet were thus investigated at steelmaking temperature using Fluent software, and a detailed chemical kinetic reaction mecha- nism was used in the combustion reaction model. The axial velocity and total temperature of the supersonic jet were measured via hot state experiments. The simulation results were compared with the experimental data and the empirical jet model proposed by Ito and Muchi and good consistency was obtained. The research results indicated that the potential core length of the coherent jet can be prolonged by optimizing the combustion effect of the fuel gas. Besides, the behavior of the supersonic jet in the subsonic section was also investigated, as it is an important factor for controlling the position of the oxygen lance. The investigation indicated that the attenuation of the coherent jet is more notable than that of the conventional jet in the subsonic section.

关键词： Supersonic jet Numerical simulation Mixed fuel gas Flow field Combustion characteristic