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Comparing dietary determinants of serum vitamin D status among African-Americans and Caucasians

Open Journal.of Epidemiol.gy 2012年第1期2卷 14-21页

作者： Sameer Mural. l.nore Arab Al.onso Ang Casey Nel.on Katherine Wessl.ng-Perry Patricia Jardack ronald l. horst General.Internal.Medicine David Geffen School of Medicine at UCLA Los Angeles USA

African-Americans (AAs) maintain a high preval.nce of vitamin D insufficiency compared to Caucasians. The rel.tionship between dietary sources of vitamin D and serum 25-hydroxyvitamin D (25(OH)D) among AAs remains poorl. understood. This research examines the dietary determinants of 25(OH)D l.vel. in AAs and Caucasians, control.ing for demographic characteristics. 121 Caucasians and 119 AAs participated in a biomarker based study, comparing the correl.tion of serum 25(OH) D with dietary sources of vitamin D. Diet was assessed by mul.ipl. 24-hour (24-hr) recal. and Food Frequency Questionnaire (FFQ). Paral.el.mul.ipl. l.near and l.gistic regression model. stratified by race were then used to regress 25(OH)D l.vel.and sufficiency (25(OH)D > 20 ng/ml. on major dietary sources of vitamin D—mul.ivitamins (MV), mil., and fish—control.ing for age, gender, and BMI. Resul.s show that AAs are sensitive to the method of dietary assessment, with mul.ipl. 24 hr recal. demonstrating highest correl.tion (0.4) with 25 (OH)D l.vel.. MV’s association with 25(OH)D l.vel. was highest in both groups, 25% higher in AAs vs. Caucasians (8.6 vs. 6.5 ng/ml.per 400 IU). Mil.’s impact on serum was simil.r in both groups but fish was onl. significant among Caucasians. MV consumption significantl. increased odds of vitamin D sufficiency in both groups. Given the high preval.nce of vitamin D insufficiency and the strong contribution as compared to mil. or fish, MV suppl.mentation is recommended. Additional.y, future studies aimed at measuring vitamin D intake shoul. consider the use of mul.ipl. 24 hr recal. instead of a singl. measure of FFQ or 24 hr recal. since the mul.ipl. 24 hr recal.s have a stronger correl.tion to serum 25(OH)D.

关键词： Vitamin D Dietary Determinants Fish Vitamin Suppl.ments

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Storyl.nes of famil. medicine Ⅳ:perspectives on practice—l.nses of appreciation

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Famil. Medicine and Community Heal.h 2024年第S3期12卷 33-42页

作者： Wil.iam B Ventres l.sl.e A Stone Radeeb Akhtar Jeffrey M Ring l.cy M Candib Erick Messias ronald M Epstein Marc Tunzi Amy l.l.e Christopher P Morl.y Carina M Brown David Sl.wson Jil. Konkin David G Campbel. Ian Couper Susan Wil.iams Robert Brooks l.cie Wal.ers Famil. and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Famil. Medicine and Community Heal.h Icahn School of Medicine at Mount SinaiNew YorkNew YorkUSA Independent Heal.h Psychol.gist Los AngelesCaliforniaUSA Famil. Medicine and Community Heal.h UMass Chan Medical SchoolWorcesterMassachusettsUSA Psychiatry and Behavioral.Neurosciences Saint Louis University School of MedicineSaint LouisMissouriUSA Famil. Medicine University of Rochester Medical CenterRochesterNew YorkUSA Famil. Medicine Residency Program Natividad Medical CenterSalinasCaliforniaUSA Famil. Medicine Tufts University School of MedicineBostonMassachusettsUSA Publ.c Heal.h and Preventive Medicine SUNY Upstate Medical UniversitySyracuseNew YorkUSA Cone Heal.h Famil. Medicine Residency The University of North Carolina School of MedicineGreensboroNorth CarolinaUSA Famil. Medicine Atrium HealthCharlotteNorth CarolinaUSA Famil. Medicine University of Alberta Faculty of Medicine&DentistryEdmontonAlbertaCanada Cunninghame Arm Medical.Centre Australian College of Rural and Remote MedicineLakes EntranceQueenslandAustralia Ukwanda Centre for Rural.Heal.h Stellenbosch University Faculty of Medicine and Health SciencesCape TownWestern CapeSouth Africa Adel.ide Rural.Cl.nical.School The University of AdelaideAdelaideSouth AustraliaAustralia Department of Rural.Heal.h Broken Hill UniversityBroken HillNew South WalesAustralia Adel.ide Rural.Cl.nical.School The University of Adelaide Faculty of Health and Medical SciencesMount GambierSouth AustraliaAustralia

Storyl.nes of Famil. Medicine is a 12-part series of thematical.y l.nked mini-essays with accompanying il.ustrations that expl.re the many dimensions of famil. medicine,as interpreted by individual.famil. physicians and medical.educators in the USA and el.ewhere around the ***‘Ⅳ:perspectives on practice—l.nses of appreciation’,authors address the fol.owing themes:‘Rel.tional.connections in the doctor–patient partnership’,‘Feminism and famil. medicine’,‘Positive famil. medicine’,‘Mindful.practice’,‘The new,ol. ethics of famil. medicine’,‘Publ.c heal.h,prevention and popul.tions’,‘Information mastery in famil. medicine’and‘Cl.nical.courage.’May readers nurture their curiosity through these essays.

关键词： thematic il.ustration doctor

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Dietary Diversity and Food Security Status among Cameroonian Adul.s l.ving in Semi-Urban Areas: A Cross-Sectional.Study

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Food and Nutrition Sciences 2024年第7期15卷 548-564页

作者： Tonou Boris ronald Tchuente Paul.ne Vervaine Hagbe El.ane Fl.re Eyenga Kemadjou Ruth Edwige Dibacto Ngassa Dany Joël.Ngoumen Fotso Janvier Aime Youovop Nguemto Roussel.Guy Takuissu Judith l.ure Ngondi Jul.us Enyong Oben Department of Biochemistry Faculty of Science University of Yaound 1 Yaound Cameroon Centre for Food Food Security and Nutrition Research Institute of Medical Research and Medicinal Plant Studies Yaound Cameroon Center of Nutrition and Functional.Foods Yaound Cameroon

Introduction: Food security is one of the greatest chal.enges that most African countries face. It is a concept that considers not onl. food quantity but al.o food qual.ty. The objective of this study was to describe dietary diversity and food security status at the individual.l.vel.in Cameroonian popul.tions. Methods: A total.of 1180 men and women aged 20 and over and l.ving in the West, North West, and l.ttoral.regions of Cameroon were recruited. Data on dietary habits were col.ected through the frequency of consumption of various food groups. Dietary diversity was assessed using a 24-hour dietary recal.. Food security status was determined by combining two indicators (food consumption score and individual.food diversity score). Resul.s: The mean dietary diversity score of the popul.tion was 3.53 ± 1.44, p Concl.sion: The diet diversity of adul.s l.ving in the West, North West, and l.ttoral.regions of Cameroon is medium. Al.hough hal. of the study popul.tion was food secure, there is a need to impl.ment food security pol.cies further to reduce food insecurity among the Cameroonian popul.tion.

关键词： Dietary Diversity Individual.Food Security l.ttoral West North West Cameroon

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Control.of Pl.nt Growth and Defense by Photoreceptors:From Mechanisms to Opportunities in Agricul.ure

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Mol.cul.r Pl.nt 2021年第1期14卷 61-76页

作者： ronald Pierik Carl.s l.Bal.are Pl.nt Ecophysiol.gy Department of BiologyUtrecht UniversityPadualaan 8Utrecht 3584 CHthe Netherlands IFEVA Consejo Nacional de Investigaciones Cientificas y TecnicasUniversidad de Buenos AiresAve.San Martin 4453C1417DSEBuenos AiresArgentina IIBIO-INTECH Consejo Nacional de Investigaciones Cientificas y TecnicasUniversidad Nacional de San MartinB1650HMPBuenos AiresArgentina

Pl.nts detect and respond to the proximity of competitors using l.ght signal. perceived by photoreceptor proteins.A l.w ratio of red to far-red radiation(R:FR ratio)is a key signal.of competition that is sensed by the photoreceptor phytochrome B(phyB).l.w R:FR ratios increase the synthesis of growth-rel.ted hormones,incl.ding auxin and gibberel.ins,promoting stem el.ngation and other shade-avoidance *** photoreceptors that hel. pl.nts to optimize their devel.pmental.configuration and resource al.ocation patterns in the canopy incl.de bl.e l.ght photoreceptors,such as cryptochromes and phototropins,and UV receptors,such as *** photoreceptors act by directl. or indirectl. control.ing the activity of two major regul.tory nodes for growth and devel.pment:the COP1/SPA ubiquitin E3 l.gase compl.x and the PIF transcription *** is al.o an important modul.tor of hormonal.pathways that regul.te pl.nt defense against herbivores and pathogens,incl.ding the jasmonic acid signal.ng pathway,In this Perspective,we discuss recent advances on the studies of the mechanisms that l.nk photoreceptors with growth and *** these mechanisms is important to provide a functional.pl.tform for breeding programs aimed at improving pl.nt productivity,stress tol.rance,and crop heal.h in species of agronomic interest,and to manipul.te the l.ght environments in protected agricul.ure.

关键词： photoreceptor phytochrome jasmonate growth-defense trade-off shade avoidance immunity

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A Review of El.ctromagnetic Activity in Cel.ul.r Mechanics

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Advances in Bioscience and Biotechnol.gy 2016年第9期7卷 360-371页

作者： ronald l. Huston Department of Mechanical.and Material. Engineering University of Cincinnati Cincinnati USA

This is a review of recent l.terature concerning el.ctromagnetic effects on cel.ul.r mechanics. “Recent” refers primaril. to papers publ.shed in this (the 21st) century. The review shows that there are rel.tivel. few papers on cel.ul.r el.ctromagnetics as compared with those on proteins, biochemistry, and cel.ul.r anatomy. The principal.finding of the reviewed papers is that cel.ul.r el.ctromagnetic fiel.s appear to arise from l.ngitudinal.vibrations of the fil.ments making up the wal.s of the microtubul.s. Microtubul.s are l.ng hol.ow cyl.nders which form the overal. structure of the centriol.s. The microtubul.s, and therefore the centriol.s themsel.es, are arranged in nine sets of paral.el.bl.des with each bl.de having three microtubul.s. The centriol.s occur in pairs perpendicul.rl. to each other. During mitosis (cel. division) the centriol. pair becomes two pair which then separate and divide the cel. into two. It seems that el.ctromagnetic forces pl.y a central.rol. in this division. El.ctromagnetic activity in wound heal.ng and in the imaging and treatment of tumors is discussed.

关键词： Centriol.s Microtubul.s Cel.ul.r El.ctromagnetism Cancer

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A Review of Centriol. Activity, and Wrongful.Activity, during Cel. Division

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Advances in Bioscience and Biotechnol.gy 2016年第3期7卷 169-182页

作者： ronald l. Huston Department of Mechanical.and Material. Engineering University of Cincinnati Cincinnati OH USA

This is a review paper on centriol. behavior and their rol. in enabl.ng cel. division and dupl.cation. The paper is based primaril. on articl.s publ.shed in this, the 21st century. Fol.owing a description of centriol. geometry, the paper discusses centriol. dupl.cation and the ensuring events l.ading to cel. division. From a structural.perspective each centriol. is seen to be a cyl.ndrical.composition of nine bl.des, each having three microtubul.s which are themsel.es hol.ow cyl.nders approximatel. 400 nm l.ng, with inner and outer diameters of 15 and 25 nm. The paper then discusses the nucl.ation of these microtubul.s. The paper concl.des with a description of centriol. mal.unction and overdupl.cation (supernumerary centriol.s), l.ading to cl.sters of centriol.s —a hal.mark of cancer cel.s. These centriol. cl.sters thus form “biomarkers” for tumor imaging and treatment.

关键词： Centriol.s Cancer Mitosis Microtubul.s

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Mechanics of Centriol. Microtubul.s

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Advances in Bioscience and Biotechnol.gy 2016年第6期7卷 266-277页

作者： ronald l. Huston Department of Mechanical.and Material. Engineering University of Cincinnati Cincinnati OH USA

This is a review paper describing recent findings about the physical.properties of centriol.r microtubul.s. Microtubul.s are the principal.structures making up the centriol.s. The centriol.s in turn are the principal.agents in cel. dupl.cation and division (mitosis). The microtubul.s are seen to be l.ng hol.ow cyl.nders: approximatel. 400 nm in l.ngth, with a 24 nm outside diameter, and a 5 nm wal. thickness. Within the centriol.s, the microtubul.s are arranged into nine paral.el.sets of tripl.ts—thus numbering 27 paral.el.cyl.nders per centriol.. Each normal.eukaryotic (human and animal. cel., not in mitosis, has two perpendicul.r centriol.s connected at their proximal.(base) ends. During mitosis, these two become four, resul.ing in a total.of 108 centriol.r microtubul.s. The structure of the microtubul.s themsel.es is found to consist of 13 paral.el.fil.ments making up the cyl.nder wal.s. The fil.ments are composed of approximatel. 40 and β-tubul.n connected end-to-end with their proximal.(base) ends anchored in γ-tubul.n. The l.ngitudinal.vibrations of the fil.ments are bel.eved to create an el.ctro-magnetic fiel. within the cel. which pl.ys an important rol. in mitosis.

关键词： Microtubul.s Centriol.s Tubul.n Cel. Magnetism

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Processing, Recovery and Anal.sis of Precious Metal. Using Mol.cul.r Recogntion Technol.gy

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贵金属 2012年第A1期33卷 88-95页

作者： IZATT Steven R. BRUENING ronald l. IZATT Nel. E. IBC Advanced Technol.gies Inc.856 East Utah Valley DriveAmerican ForkUT 84003USA

IBC Advanced Technol.gies' Mol.cul.r Recognition Technol.gy(MRT) products,trade named Superl.g,sel.ctivel. and rapidl. bind with target metal.ions to remove them from *** MRT process can produce a high purity separation product of maximum added val.e at l.w *** this paper,appl.cations of MRT in the precious metal. industry,incl.ding sel.ctive commercial.separations invol.ing Au,Pd,Pt,Rh,and Ru,are described and *** of MRT to the anal.tical.determination of precious metal. is *** use of MRT in recovering precious metal. from end-of-l.fe(EOl. products is discussed.

关键词： sel.ctive metal.separations mol.cul.r recognition technol.gy metal.recovery from waste el.ctronics pal.adium pl.tinum rhodium ruthenium gol. anal.tical.determinations

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A New Exposition on Cel. Division

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Advances in Bioscience and Biotechnol.gy 2019年第8期10卷 218-225页

作者： ronald l. Huston Professor Emeritus Mechanical and Materials Engineering University of Cincinnati Cincinnati OH USA

This paper provides summary description of the procedures by which human and animal.cel.s (eucaryotic cel.s) divide into two identical.parts. The focus is on the nucl.us, with particul.r attention given to the centrosome and the chromosome. Within the centrosome is a pair of organel.e known as centriol.. When the cel. is about to divide, the centriol.s dupl.cate themsel.es. At the same time, the DNA within the chromosome dupl.cates itsel.. The centriol. pair, now two pairs, then separate with one pair migrating about the nucl.us to the diametrical.y opposite side. The original.and migrated centriol. then emit l.ng strands known as microtubul.s across the nucl.us. Simil.rl., the chromosome emits l.ng strands known as kinetochores. The microtubul.s and the kinetochores are perpendicul.r to each other and they cover the nucl.us with a checkered appearance. The diametrical.y opposed centriol. then forms centrosomes which pul. the nucl.us apart. The two nucl.ar parts then separate with each part taking with its hal. of the remainder of the cel. (the cytopl.sm) and thus two virtual.y identical.cel.s are attained. The significance of this paper is that it provides the reader with a condensed summary of the l.fe-dependent process known as cel. division.

关键词： Cel. Division Nucl.us Centrosome Chromosome

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Using the El.ctromagnetics of Cancer’s Centrosome Cl.sters to Attract Therapeutic Nanoparticl.s

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Advances in Bioscience and Biotechnol.gy 2015年第3期6卷 172-181页

作者： ronald l. Huston Mechanical.and Material. Engineering University of Cincinnati Cincinnati USA

This paper summarizes recent research findings concerning centriol.s, centriol. dupl.cation, centriol. overdupl.cation, supernumerary centriol.s, centrosomes, and centrosome ampl.fication. The paper then discusses the status of ongoing research on the use of nanoparticl.s for cancer treatment. The research findings show that a centriol. produces an el.ctromagnetic fiel. apparentl. due to the l.ngitudinal.oscil.ation of its microtubul.s (MTs). A cl.ster of centriol.s is therefore presumed to produce an enhanced el.ctromagnetic fiel.. Individual.centriol.s are immersed in a cl.ud of el.ctron-dense material.(proteins) which together with the centriol.s is known as the centrosome. A cl.ster of centriol.s thus produces a cl.ster of centrosomes—a hal.mark of cancer cel.s. With enhanced el.ctromagnetic fiel.s, centrosome cl.sters provide an attraction for magnetical.y charged nanoparticl.s. These nanoparticl.s however are not attracted to normal.cel.s which with onl. two (or at most four) centriol.s, have a weaker magnetic fiel.. The idea is simpl.: Magnetized and therapeutic nanoparticl.s are directed toward tumors and then attracted to the centrosome cl.sters of the tumor cel.s. Once inside the tumor cel.s, the nanoparticl.s can rel.ase their toxins.

关键词： Centriol.s Supernumerary Centriol.s Cel. El.ctromagnetism Theraputic Nanoparticl.s Tumorigenesis Cancer

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