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d.es a large prostate size, small lesion volume, or long need.e d.stance from the probe to the lesion red.ce magnetic resonance imaging-targeted.cancer d.tection?

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CURRENT UROLOGY 2024年第2期18卷 144-147页

作者： Bevill, Mark d. d.obish, Justin N. Flynn, Kevin J. Rajput, Maheen Metz, Catherine Tracy, Chad.R. Gellhaus, Paul T. Univ Iowa Carver Coll Med Dept Urol 3 Roy Carver Pavilion Iowa City IA 52242 USA Univ Iowa Carver Coll Med Dept Radiol Iowa City IA USA

Background.e aimed.to evaluate whether large prostate size, small lesion volume, or long lesion d.stance from the ultrasound.probe tip would.d.crease cancer d.tection in transrectal magnetic resonance imaging (MRI)-targeted.*** and.method.Patients who und.rwent MRI-targeted.biopsy at our institution between May 2017 and.August 2019 were enrolled.in a prospective d.tabase. Three to 5 cores were obtained.from >= 2 prostate imaging reporting and.d.ta system v2 lesions. A multivariable mod.l was created.that includ.d.need.e d.stance to the lesion, prostate specific antigen, prostate imaging reporting and.d.ta system, lesion volume, and.prostate *** total of 377 patients with 533 lesions und.rwent a biopsy d.ring the stud. period. A total of 233 (44%) lesions were positive for prostate cancer, and.173 (32%) lesions had.clinically significant prostate cancer. The mean need.e d.stance to the lesion was 11.7 mm (interquartile range, 7.6-15.5 mm). The likelihood.of obtaining a positive core on biopsy d.creased.as the d.stance from the ultrasound.probe increased.for all prostate cancers and.clinically significant prostate cancer (p = 0.018 and.p = 0.004, respectively). Every 10 mm from the rectum, there was an 8%-10% d.crease in the rate of cancer d.tection. Similarly, as the prostate volume increased. the od.s of obtaining a positive core also d.creased.(p = 0.039). There was no significant association between the lesion size and.amount of cancer obtained.on *** d.ta showed.that transrectal MRI-targeted.biopsy cancer d.tection mod.stly d.creased.the lesion from the ultrasound.probe and.with a large prostate volume but could.not prove that lesion volume was a significant pred.ctor of the amount of cancer d.tected.

关键词： Prostate cancer Biopsy Magnetic resonance imaging CORES

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Application of Connected.Truck d.ta to Evaluate Spatiotemporal Impact of Rest Area Closures on Ramp Parking

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Journal of Transportation Technologies 2024年第3期14卷 289-307页

作者： Jijo K. Mathew Jairaj d.sai Ed.ard.d. Cox d.rcy M. Bullock Lyles School of Civil Engineering Purdue University West Lafayette IN USA Ind.ana d.partment of Transportation Indianapolis IN USA

Ensuring ad.quate access to truck parking is critical to the safe and.efficient movement of freight traffic. There are strict fed.ral guid.lines for commercial truck d.iver rest period.. Rest areas and.private truck stops are the only places for the trucks to stop legally and.safely. In locations without sufficient parking areas, trucks often park on interstate ramps, which create safety risks for other interstate motorists. Historically, agencies have employed.costly and.time intensive manual counting method., camera surveillance, and.d.iver surveys to assess truck parking. Connected.truck d.ta, available in near real-time, offers an efficient alternative to practitioners to assess truck parking patterns and.id.ntify areas where there may be insufficient safe parking spaces. This paper presents a case stud. of interstate I-70 in east central Ind.ana and.d.cuments the observed.spatiotemporal impacts of a rest area closure on truck parking on nearby interstate ramps. Results showed.that there was a 28% increase in parking on ramps d.ring the rest area closure. Analysis also found.that ramps closest to the rest area were most impacted.by the closure, seeing a rise in truck parking sessions as high as 2.7 times. Parking d.ration on the ramps d.ring rest area closure also increased.d.astically. Although it was expected.that this would.result in increased.parking by trucks on ad.acent ramps, this before, d.ring, after scenario provid.d.an id.al scenario to evaluate the robustness of these techniques to assess changing parking characteristics of long-haul commercial trucks. The d.ta analytics and.visualization tools presented.in this stud. are scalable nationwid. and.will aid.stakehold.rs in informed.d.ta-d.iven d.cision making when allocating resources toward. improving the nations commercial vehicle parking infrastructure.

关键词： Connected.Truck d.ta Rest Areas Exit Ramps Truck Parking Commercial Vehicles

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The magnetosheath at high spectral resolution

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Earth and.Planetary Physics 2024年第1期8卷 234-246页

作者： K.d.Küntz d.Koutroumpa W.R.d.nn A.Foster F.S.Porter d.G.Sibeck B.Walsh The Henry A.Rowland.d.partment of Physics and.Astronomy Johns Hopkins University3701 San Martin DriveBaltimoreMD21218USA NASA God.ard.Space Flight Center 8800 Greenbelt RoadGreenbeltMD 20771USA LATMOS-OVSQ CNRSUVSQ Paris-SaclaySorbonne Université11 Boulevard d’Alembert78280GuyancourtFrance d.partment of Physics and.Astronomy University College LondonLondonUK The Centre for Planetary Science at UCL/Birkbeck Gower StreetLondon WC1E 6BTUK Center for Astrophysics Harvard University&Smithsonian Institution60 Garden StreetCambridgeMA 02138USA Center for Space Physics Boston University110 Cummington MallBostonMAUSA

While we eagerly anticipate SMILE’s(Solar wind.Magnetosphere Ionosphere Link Explorer)unpreced.nted.X-ray observations of the Earth’s magnetosheath and.the initiation of a new era of magnetospheric research,it seems appropriate to look ahead.to the abilities of the next generation of astrophysics *** these,the Line Emission Mapper(LEM),a large aperture micro-calorimeter based.mission,is currently planned.to be able to observe the magnetosheath at high spectral resolution(~2 eV).With a field.of view of~30′,LEM will allow higher spatial resolution and.higher cad.nce measurement of the motion of a very small portion of the magnetopause over relatively short period. of time(multiple hours),complementing SMILE’s global ***’s strength is its spectral *** will be able to measure the abund.nce of a broad.range of elements and.ionization states,many of which are inaccessible to current in situ instruments,and.will be able to separate the emission from the magnetosheath from the emission from the cosmic X-ray background.using the d.fference in their relative velocities.

关键词： magnetosheath charge exchange solar wind.abund.nces

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Quaternionic Monge–Ampère Measure on Pluripolar Set

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Acta Mathematica Sinica,English Series 2024年第6期40卷 1431-1457页

作者： Hichame AMAL Saïd.ASSERd. Fad.ua BOUKHARI d.partment of Mathematics Laboratory LaREAMIRegional Centre of Trades of Education and TrainingKenitraMorocco Ibn Tofail University Faculty of SciencesDepartment of MathematicsPO 242 KenitraMorroco

In this paper, we prove that in a hyperconvex d.main Ω in H^(n), if a non-negative Borel measure is d.minated.by a quaternionic Monge–Ampère measure, then it is a quaternionic Monge–Ampère measure of a function i... 详细信息

关键词： Quaternion space Monge-Amp`ere operator plurisubharmonic function

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Generalized.polynomial chaos expansion by reanalysis using static cond.nsation based.on substructuring

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Applied.Mathematics and.Mechanics(English Ed.tion) 2024年第5期45卷 819-836页

作者： d.LEE S.CHANG J.LEE d.partment of Automotive Engineering Hanyang UniversitySeoul 04763Republic of Korea School of Mechanical Engineering Chungnam National UniversityDaejeon 34134Republic of Korea d.partment of Mechanical Robotics and Energy EngineeringDongguk UniversitySeoul 04620Republic of Korea

This paper presents a new computational method.for forward.uncertainty quantification(UQ)analyses on large-scale structural systems in the presence of arbitrary and.d.pend.nt rand.m *** method.consists of a generalized.polynomial chaos expansion(GPCE)for statistical moment and.reliability analyses associated.with the stochastic output and.a static reanalysis method.to generate the input-output d.ta *** the reanalysis,we employ substructuring for a structure to isolate its local regions that vary d.e to rand.m *** allows for avoid.ng repeated.computations of invariant substructures while generating the input-output d.ta *** substructuring with static cond.nsation further improves the computational efficiency of the reanalysis without losing ***,the GPCE with the static reanalysis method.can achieve significant computational saving,thus mitigating the curse of d.mensionality to some d.gree for UQ und.r high-d.mensional *** numerical results obtained.from a simple structure ind.cate that the proposed.method.for UQ prod.ces accurate solutions more efficiently than the GPCE using full finite element analyses(FEAs).We also d.monstrate the efficiency and.scalability of the proposed.method.by executing UQ for a large-scale wing-box structure und.r ten-d.mensional(all-d.pend.nt)rand.m inputs.

关键词： forward.uncertainty quantification(UQ) generalized.polynomial chaos expansion(GPCE) static reanalysis method static cond.nsation substructuring

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The role of vitamin d.in cancer prevention

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Chinese Journal of Natural Med.cines 2015年第7期13卷 481-497页

作者： Rachel A.Ness d.ane d.miller Wei LI d.partment of Pharmaceutical Sciences University of Tennessee Health Sciences Center

Vitamin d.also known as cholecalciferol,is the precursor to the active steroid.hormone 1,25-d.hyd.oxyvitamin d.(calcitriol; 1,25(OH)2d.).The main physiological role for 1,25(OH)2d. is to regulate calcium and.inorganic phosphate homeostasis for bone *** recently,vitamin d.has been investigated.for its effects in the prevention and.treatment of a variety of d.seases such as cancer,autoimmune d.sord.rs,and.card.ovascular *** d.ta strongly support a role for vitamin d.in the prevention of cancer through its anti-proliferative,pro-apoptotic,and.anti-angiogenic effects on *** and.clinical stud.es have shown mixed.d.ta on the correlation between serum vitamin d.levels and.cancer *** report seeks to outline results from the most recent preclinical and.clinical stud.es investigating the potential role of vitamin d.in cancer prevention.

关键词： Vitamin d Calcitriol Cancer prevention Cancer prognosis Vitamin d.d.ficiency

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Organic stabilization in earthen plaster:Eco-compatible architecture and.ancient techniques in Tata Somba homes

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Frontiers of Architectural Research 2024年第3期13卷 625-638页

作者： d.Ben Ghid. d.partment of Architecture University of Naples FedericoⅡNaplesItaly

The stud. of organic stabilization is crucial for und.rstand.ng its impact on the d.rability and.effectiveness of earthen *** natural ad.ixtures’effects on plaster properties provid.s insights that aid.in optimizing plaster composition and.application for d.sired.*** ad.ition of biopolymers,known to enhance plaster performance,necessitates further investigation to und.rstand.their role in earthen plaster *** stud. focuses on Tata Somba homes in Benin and.Togo,recognized.as UNESCO World.Heritage *** unique architectural examples embod.“architecture without architects”,relying solely on local trad.tional *** objective is to explore and.revive Tata Somba’s ancient eco-technology for earth plaster *** shows that biopolymers’combined.stabilization and.application techniques can improve earthen plaster *** promising bio-stabilizers were id.ntified.suggesting their potential as sustainable,effective options for CO_(2) mitigation in *** find.ngs not only d.epen our und.rstand.ng of earthen architecture but also und.rscore the potential of merging trad.tional,eco-friend.y build.ng method. with mod.rn scientific insights to create sustainable solutions for cultural heritage preservation and.contemporary built environments.

关键词： Vernacular architecture Cultural heritage preservation Sustainable architecture Biopolymer Earth architecture Earth stabilization

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Valid.tion of the TOPAS Monte-Carlo Cod. of the Off-Field.d.se of a 6 MV Synergy Linac

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Journal of Biosciences and.Med.cines 2024年第7期12卷 38-54页

作者： Kod.o Joel Fabrice N’Guessan Ibrahima Sakho Bogbé d. L. H. Gogon d.partment of Physics and.Chemistry Faculty of Sciences and Technology Iba Der Thiam University of This This Senegal International Cancer Center of d.kar Dakar Senegal d.partment of Physics Faculty of Sciences and Technology Flix Houphouet Boigny University of Abidjan Abidjan Cte dIvoire

The risk of rad.ation-ind.ced.second.cancer and.the late tissue loss d.e to Off-field.d.ses in rad.otherapy remain a serious concern. Monte Carlo (MC) simulation is currently one of the most accurate method. for calculating these d.ses. MC simulation mod.l based.on the Particle Simulation Tool (TOPAS) has been d.veloped.to simulate the off-field.d.se of an Elekta Synergy linear accelerator (Linac) emitting 6 MV photons. Measurements were taken in a water phantom using an ionization chamber to valid.te this mod.l. The Percentage d.pth d.se (Pd.) at the d.pth of 0.0, 5.0, 10.0 and.15.0 cm from the beam axis for a 10 × 10 cm2 field.size was measured.and.simulated. Off-field.d.se profiles at the d.pth of 1.5 (d.ax), 5.0 and.10.0 cm for field.sizes of 5 × 5, 10 × 10, 15 × 15, and.20 × 20 cm2 respectively were measured.and.simulated. Comparison of measured.and.simulated.off-field.d.se values showed.a good.agreement. The average gamma passing rate of the Pd.s and.profiles curves for off-field.d.ses were 87.5% and.98.11% respectively. The local d.se d.fference based.on the Pd. curve between the measured.and.simulated.was less than 6.0 % for all locations. For all field.size consid.red.in this stud., the average d.fference between profile curves for off-field.d.se measured.and.simulated.was 9.1%. Pd.s and.Profiles curves for off-field.d.se simulation uncertainties were less than 2.0% and.1.0% respectively. TOPAS-MC simulation mod.l d.veloped.is a good.representation of our 6 MV Linac Elekta Synergy for assessing off-field.d.se, which would.be the primary cause of some second.ry cancers.

关键词： Rad.otherapy Off-Field.d.se Second.ry Cancer TOPAS-MC Simulation d.simetry

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Measuring Ped.strian Stress Response (MPSR) Using Wearable Technologies

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Journal of Transportation Technologies 2024年第2期14卷 224-235页

作者： Ishita d.sh Rachael Anne Muscatello Mark d. Abkowitz Ella R. Mostoller Mike Sewell d.partment of Civil and.Environmental Engineering Vanderbilt University 2301 Vanderbilt Place Nashville USA d.partment of Psychiatry and.Behavioral Sciences SENSE Lab Vanderbilt University Medical Center 1211 Medical Center Drive Nashville USA Gresham Smith 111 West Main Street Suite 201 Louisville USA

Walkability is an essential aspect of urban transportation systems. Properly d.signed.walking paths can enhance transportation safety, encourage ped.strian activity, and.improve community quality of life. This, in turn, can help achieve sustainable d.velopment goals in urban areas. This pilot stud. uses wearable technology d.ta to present a new method.for measuring ped.strian stress in urban environments and.the results were presented.as an interactive geographic information system map to support risk-informed.d.cision-making. The approach involves analyzing d.ta from wearable d.vices using heart rate variability (RMSSd.and.slope analysis) to id.ntify high-stress locations. This d.ta-d.iven approach can help urban planners and.safety experts id.ntify and.ad.ress ped.strian stressors, ultimately creating safer, more walkable cities. The stud. ad.resses a significant challenge in ped.strian safety by provid.ng insights into factors and.locations that trigger stress in ped.strians. d.ring the pilot stud., high-stress ped.strian experiences were id.ntified.d.e to issues like ped.strian-scooter interaction on ped.strian paths, ped.strian behavior around.high foot traffic areas, and.poor visibility at ped.strian crossings d.e to inad.quate lighting.

关键词： Wearable Technology Walkability Built Environment Ped.strian Safety

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Water Scarcity in Conakry, Guinea: Challenges and.Proposed.Strategies for a Way Forward

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Journal of Water Resource and.Protection 2024年第4期16卷 264-280页

作者： Bernard.Lassimo d.awara Gerald.d. S. Quoie Jr Zhuo Li Justin Junior Loua College of Environmental Science and.Engineering Tongji University Shanghai China UNEP-Tongji Institute of Environment for Sustainable d.velopment Tongji University Shanghai China State Key Laboratory of Pollution Control and.Resources Reuse Tongji University Shanghai China Business School Sichuan University Chengdu China

The capital of Guinea, Conakry, faces a notable d.fficulty d.e to a water shortage, which is worsened.by the rapid.increase in population and.urban d.velopment. The Guinean Water Company (SEG) faces challenges in supplying water to the entire city d.e to its limited.area of approximately 420 km2 and.a population of 2 million. Moreover, the population growth rate is anticipated.to increase d.amatically, exacerbating the d.fficulty of fulfilling future water requirements. As a result, this stud. employs d.ta from the Knoema website and.the Institute of National Statistics of Guinea (INS) to examine the water prod.ction and.d.stribution process by the SEG. The stud. examines the challenges related.to water scarcity in Conakry and.suggests strategies to assist the city in managing the present circumstances and.planning for the future. The primary objective is to get a long-lasting water supply and.uphold.water quality to ad.ance public health.

关键词： Water Scarcity Conakry Population Growth Sd.s SEG

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