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论文-引文矩阵及其推导的定量评价指标

科学通报 2001年第8期46卷 700-704页

作者： P. Ingwersen B. Larsen R. rousseau J. Russell Royal School of Library and Information Science Department of Information Studies & Center for Informetric Studies Birketinget 6 DK2300 Copenhagen S Denmark

对论文－引文矩阵的主要数据进行了分析．介绍了影响因子的定义；指出了同时影响因子和历时影响因子的差别；并且讨论了使用两种影响因子进行科研评价的优缺点．建议将历时影响因子作为测度值，与被评价论文的预期影响因子，即学科引文... 详细信息

对论文－引文矩阵的主要数据进行了分析．介绍了影响因子的定义；指出了同时影响因子和历时影响因子的差别；并且讨论了使用两种影响因子进行科研评价的优缺点．建议将历时影响因子作为测度值，与被评价论文的预期影响因子，即学科引文分值进行比较．

关键词：科研估计论文-引文矩阵同时影响因子历时影响因子期刊

政治秀场VS镜头真相英联社头牌政治摄影师用快门瓦解英国大选

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摄影之友 2015年第7期 78-85页

作者： Stefan rousseau 微雪英联社

2015年5月8日,卡梅伦所领导的保守党在英国大选中赢得了胜利。在过去的六周中,各种换汤不换药的新闻照片将原本枯燥的政治演绎得更让人昏昏欲睡。Stefan rousseau和他照片的出现,犹如一匹黑马让人眼前一亮。这位英联社(Press Associati... 详细信息

2015年5月8日,卡梅伦所领导的保守党在英国大选中赢得了胜利。在过去的六周中,各种换汤不换药的新闻照片将原本枯燥的政治演绎得更让人昏昏欲睡。Stefan rousseau和他照片的出现,犹如一匹黑马让人眼前一亮。这位英联社(Press Association)的首席政治摄影师,已身处整个国家政治风暴中心二十余年,他一直试图用相机这个"发声器",勇敢地告诉民众:"作秀只会让人麻木乏味,只有镜头下的真相才能让人抖擞精神!"

关键词：卡梅伦 VS 新闻照片 Stefan 风暴中心威斯敏斯特宫电视辩论自由民主党新闻摄影报道计

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核电大国俄罗斯:灾难或在酝酿

低碳世界 2012年第7期2卷 26-28页

作者： Richard rousseau 张瑜阿塞拜疆扎尔大学政治和国际关系学院

俄罗斯民用核能的现状令全球不寒而栗:放射性核废料处理厂处理能力过剩,许多反应堆已经过时且不能满足最基本的安全标准.长此以往,或许,新的灾难正在酝酿.2011年日本福岛发生的悲剧性核灾难,造成了严重的公共健康问题.

关键词：电大俄罗斯放射性核废料灾难健康问题处理厂安全标准反应堆悲剧性日本能力民用核能公共

Dual effect of pre-ischemic administration of TNF-alpha on myocardial infarct size

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World Journal of Cardiovascular Diseases 2013年第5期3卷 21-25页

作者： Thuy Tran Quang Raja Hatem Guy rousseau Audrey-Anne Gosselin Erick Schampaert Thierry Charron Centre de Recherche Hopital du Sacré-Caeur de Montréal Montréal Canada Centre de Recherche Hopital du Sacré-Caeur de Montréal Montréal Canada Département de Pharmacologie Université de Montréal Montréal Canada Centre de Recherche Hopital du Sacré-Caeur de Montréal Montréal Canada Département de Cardiologie Hopital du Sacré-Caeur de Montréal Montréal Canada Département de Cardiologie Hopital du Sacré-Caeur de Montréal Montréal Canada

Tumour necrosis factor-α is a cytokine released during myocardial infarction. According to the literature, the effect of TNFα on myocardial infarction is controversial, especially when administered before the ischemic period. The deleterious effects of TNFα seem to be related to the triggering of apoptosis. This study has been designed to determine if different doses of TNFα, administered before the ischemic period, have the same effect on infarct size and on activation of caspase-3 and-8, two enzymes involved in apoptosis. Four groups, using a porcine model of myocardial infarction, have been used: placebo and TNFα (0.1 μg/kg;1 μg/kg and 3 μg/kg). All administered 15 minutes before a 50 minutes occlusion of the left anterior descending artery. Myocardial infarct size has been determined at 3 hours of reperfusion. In a subgroup of animals, reperfusion period has been limited to 15 min to determine the activity of caspase-3 and-8 by spectrofluorometry. Results indicated that infarct size is significantly smaller in groups 0.1 μg/kg and 1 μg/ kg as compared to the placebo group. In contrast, the 3 μg/kg group presented an infarct size similar to the placebo group. Activity of caspase-3 and-8 is reduced in the ischemic region in groups 0.1 and 1 μg/ kg as compared to the placebo group whereas activity in the 3 μg/kg group was similar to the placebo. The results obtained indicated that a low dose of TNFα administered before the ischemic period reduces infarct size, whereas the cardioprotection is lost with the high dose.

关键词： TNF-Alpha Myocardial Infarct Size Protection Apoptosis Caspase-8

Interleukin-17 mediates liver progenitor cell transformation into cancer stem cells through downregulation of miR-122

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Cancer Biology & Medicine 2018年第S1期15卷 14-15页

作者： Imène Gasmi CamiliaMachou AurélieRodrigues Julien Calderaro Benoit rousseau Arthur Brouillet Christophe Rodriguez Vanessa Demontant Guillaume Gricourt Alain Luciani Jean-Michel Pawlotsky Fouad Lafdil Université Paris-Est-Créteil CréteilFrance INSERMU955 VirusesHepatology and CancersHopital Henri MondorCréteilFrance Institut Universitaire de France(IUF) ParisFrance

Objective:Cancer stem cells(CSCs)have been the focus of several studies because oftheir involvement in cancer initiation and *** were identified in 28%to 50%of hepatocellular carcinomas(HCCs).The origin of CSCs is still unclear,but it has been recently suggested that CSCs could originate from the transformation of liver progenitor cells(LPCs)during chronic liver inflammation.

关键词： Interleukin-17 mediates liver

Understanding convergent signaling regulation in metastatic breast cancer cells using a bioengineered stem cell microenvironment

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Journal of Cancer Metastasis and Treatment 2019年第3期4卷 42-58页

作者： Bridget Mooney Yangzi Isabel Tian Erin rousseau Yubing Xie Colleges of Nanoscale Science and Engineering SUNY Polytechnic InstituteAlbanyNY 12203USA

Aim:The convergence of tumorigenic and embryonic signaling pathways drives us to exploit the embryonic stem cell(ESC)microenvironment to restrict metastatic potential of cancer *** have previously demonstrated that bioengineered ESC microenvironments could restrict growth and metastatic potential of highly aggressive breast cancer cell(BCC).This study aims to further understand the regulation of convergent EGFR and canonical Wnt/β-catenin signaling pathway function in triple negative metastatic BCCs using the 3D in vitro ESC microenvironment created by encapsulating ESCs in alginate hydrogel ***:Co-culture with ESC-microstrands increased sensitivity to two chemotherapeutic drugs in metastatic *** test whether these changes were due to restored signaling pathway regulation in BCCs,we probed for changes in gene expression of key molecules related to the EGFR and canonical Wnt/β-catenin signaling pathways using quantitative reverse transcription polymerase chain reaction and Western blot ***:ESC-microstrands are able to alter the gene expression of highly aggressive BCCs at both mRNA and protein *** changes are indicative of a reversal of EGFR and canonical Wnt/β-catenin signaling pathway hyperactivation following *** NKD2 mRNA and protein expression coinciding with dual signaling pathway inhibition within co-cultured BCCs suggests that this reversal may be attributable to restored regulation of NKD2 within these ***:ESC-microstrands are able to reverse oncogenic signaling pathway hyperactivation and restore signaling pathway regulation in metastatic *** studies could provide insight into what role NKD2 up-regulation plays ;in BCC inhibition,leading to the development of a new targeted therapy for metastatic breast cancer.

关键词： Metastasis cancer cell signaling 3D culture stem cells EGFR Wnt/β-catenin NKD2

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卢梭民主哲学 4

丛书名：哲人咖啡厅

2004年

作者：（法）卢梭（Jean rousseau）陈惟和等译

本书反映了著者的主要思想和理论，全书编为：社会契约论、人类不平等的起源和基础、爱弥儿（论教育）、忏悔者的遐想、书信集五部分。

ISBN: (数字)7801951212

ISBN: (纸本)7801951212

本书反映了著者的主要思想和理论，全书编为：社会契约论、人类不平等的起源和基础、爱弥儿（论教育）、忏悔者的遐想、书信集五部分。

关键词：卢梭J.J. 1712~1778 民主哲学思想

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武装冲突法

武装冲突法

Water treatment and reclamation by implementing electrochemical systems with constructed wetlands

丛书名：国际法译丛

1987年

作者：（法）卢梭（rousseau C.）张凝等译

书名原文: Le droit des conflits armes.

ISBN: (纸本)6220·13

书名原文: Le droit des conflits armes.

关键词：政治、法律法律(D9) 国际法

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Environmental Science and Ecotechnology 2023年第4期16卷 88-105页

作者： Suanny Mosquera-Romero Eleftheria Ntagia Diederik P.L.rousseau Abraham Esteve-Nú~nez Antonin Prevoteau Center for Microbial Ecology and Technology(CMET) Ghent UniversityCoupure Links 653B-9000GhentBelgium ESPOL Polytechnic University Escuela Superior Politécnica del LitoralESPOLFacultad de Ciencias Naturales y MatemáticasBOX9050Ecuador Department of Green Chemistry and Technology Ghent UniversitySint-Martens-Latemlaan 2BB-8500KortrijkBelgium Centre for Advanced Process Technology for Urban Resource Recovery(CAPTURE) Frieda Saeysstraat 19000GhentBelgium UniversitéParis-Saclay INRAEPROSE92160AntonyFrance Universidad de Alcalá Department of Analytical ChemistryPhysical Chemistry and Chemical EngineeringAlcaláde HenaresSpain

Seasonal or permanent water scarcity in off-grid communities can be alleviated by recycling water in decentralized wastewater treatment ***-based solutions,such as constructed wetlands(CWs),have become popular solutions for sanitation in remote *** typical CWs can efficiently remove solids and organics to meet water reuse standards,polishing remains necessary for other parameters,such as pathogens,nutrients,and recalcitrant *** CW designs and CWs coupled with electrochemical technologies have been proposed to improve treatment *** systems(ECs)have been either implemented within the CW bed(ECin-CW)or as a stage in a sequential treatment(CW+EC).A large body of literature has focused on ECin-CW,and multiple scaled-up systems have recently been successfully implemented,primarily to remove recalcitrant ***,only a few reports have explored the opportunity to polish CW effluents in a downstream electrochemical module for the electro-oxidation of micropollutants or electro-disinfection of pathogens to meet more stringent water reuse *** paper aims to critically review the opportunities,challenges,and future research directions of the different couplings of CW with EC as a decentralized technology for water treatment and recovery.

关键词： Sanitation and reuse Disinfection Advanced oxidation Decentralized systems Electrification