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Modeling and Optimisation of Precedence-Constrained Production Sequencing and Scheduling for Multiple Production Lines Using Genetic Algorithms

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Computer Technology and Application 2011年第6期2卷 487-499页

作者： Son Duy Dao romeo marian School of Advanced Manufacturing ＆ Mechanical Engineering University of South Australia Mawson Lakes SA 5095 Australia

This paper presents an integrated methodology for the modelling and optimisation of precedence-constrained production sequencing and scheduling for multiple production lines based on Genetic Algorithms (GA). The problems in this class are NP-hard combinatorial problems, requiring a triple optimisation at the same time: allocation of resources to each line, production sequencing and production scheduling within each production line. They are ubiquitous to production and manufacturing environments. Due to nature of constraints, the length of solutions for the problem can be variable. To cope with this variability, new strategies for encoding chromosomes, crossover and mutation operations have been developed. Robustness of the proposed GA is demonstrated by a complex and realistic case study.

关键词：生产线调度遗传算法优化建模优先级序列集成方法优先约束

Red cell distribution width/platelet ratio estimates the 3-year risk of decompensation in Metabolic Dysfunction-Associated Steatotic Liver Disease-induced cirrhosis

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World Journal of Gastroenterology 2024年第7期30卷 685-704页

作者： Marcello Dallio Mario romeo Paolo Vaia Salvatore Auletta Simone Mammone Marina Cipullo Luigi Sapio Angela Ragone Marco Niosi Silvio Naviglio Alessandro Federico Department of Precision Medicine Hepatogastroenterology DivisionUniversity of Campania Luigi VanvitelliNaples 80138Italy Department of Precision Medicine Clinical Biochemistry DivisionUniversity of Campania Luigi VanvitelliNaples 80138Italy

BACKGROUND For compensated advanced chronic liver disease(cACLD)patients,the first decompensation represents a dramatically worsening prognostic *** on the first decompensation event(DE),the transition to decompensated advanced chronic liver disease(dACLD)can occur through two modalities referred to as acute decompensation(AD)and non-AD(NAD),*** Significant Portal Hypertension(CSPH)is considered the strongest predictor of decompensation in these ***,due to its invasiveness and costs,CSPH is almost never evaluated in clinical ***,recognizing noninvasively predicting tools still have more appeal across healthcare *** red cell distribution width to platelet ratio(RPR)has been reported to be an indicator of hepatic fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease(MASLD).However,its predictive role for the decompensation has never been *** In this observational study,we investigated the clinical usage of RPR in predicting DEs in MASLD-related cACLD *** Fourty controls and 150 MASLD-cACLD patients were consecutively enrolled and followed up(FUP)semiannually for 3 *** baseline,biochemical,clinical,and Liver Stiffness Measurement(LSM),Child-Pugh(CP),Model for End-Stage Liver Disease(MELD),aspartate aminotransferase/platelet count ratio index(APRI),Fibrosis-4(FIB-4),Albumin-Bilirubin(ALBI),ALBI-FIB-4,and RPR were *** FUP,DEs(timing and modaities)were *** was assessed at the baseline and on DE occurrence according to the available Clinical Practice *** Of 150 MASLD-related cACLD patients,43(28.6%)progressed to dACLD at a median time of 28.9 months(29 NAD and 14 AD).Baseline RPR values were significantly higher in cACLD in comparison to controls,as well as MELD,CP,APRI,FIB-4,ALBI,ALBI-FIB-4,and LSM in dACLD-progressing compared to cACLD individuals[all P<0.0001,except for FIB-4(P:0.007)and ALBI(P:0.011)].Receiving operator curve a

关键词： Liver cirrhosis Red blood cell distribution width Red blood cell distribution width to platelet ratio Translational Medicine Prognostic biomarker

Analysis of Mobile and Internet Network Coverage: Propagation of Electromagnetic Waves and Concept of Digital Divide in Burundi

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Open Journal of Antennas and Propagation 2024年第1期12卷 1-18页

作者： Apollinaire Bigirimana Jérémie Ndikumagenge Sami Tabbane romeo Nibitanga Hassan Kibeya Center for Research in Infrastructure Environment and Technology (CRIET) Doctoral School of the University of Burundi Bujumbura Burundi Center for Research in Infrastructure Environment and Technology (CRIET) University of Burundi Bujumbura Burundi Higher School of Communications of Tunis Technological City of Communications Ariana Tunisia Faculty of Engineering Sciences Universit du Burundi Bujumbura Burundi

Mobile and Internet network coverage plays an important role in digital transformation and the exploitation of new services. The evolution of mobile networks from the first generation (1G) to the 5th generation is still a long process. 2G networks have developed the messaging service, which complements the already operational voice service. 2G technology has rapidly progressed to the third generation (3G), incorporating multimedia data transmission techniques. It then progressed to fourth generation (4G) and LTE (Long Term Evolution), increasing the transmission speed to improve 3G. Currently, developed countries have already moved to 5G. In developing countries, including Burundi, a member of the East African Community (ECA) where more than 80% are connected to 2G technologies, 40% are connected to the 3G network and 25% to the 4G network and are not yet connected to the 5G network and then still a process. The objective of this article is to analyze the coverage of 2G, 3G and 4G networks in Burundi. This analysis will make it possible to identify possible deficits in order to reduce the digital divide between connected urban areas and remote rural areas. Furthermore, this analysis will draw the attention of decision-makers to the need to deploy networks and coverage to allow the population to access mobile and Internet services and thus enable the digitalization of the population. Finally, this article shows the level of coverage, the digital divide and an overview of the deployment of base stations (BTS) throughout the country to promote the transformation and digital inclusion of services.

关键词： Coverage of Mobile Networks and Internet Digital Divide Rural and Isolated Areas Antenna Connectivity and Digital Inclusion

Smart cities from low cost to expensive solutions under an optimal analysis

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Financial Innovation 2023年第1期9卷 1660-1693页

作者： romeo‑Victor Ionescu Monica Laura Zlati Valentin‑marian Antohi Dunarea de Jos University 111thDomneasca Street800201 GalatiRomania Dunarea de Jos University Nicolae BalcescuStreetNo.59‑61800001 GalatiRomania Department of Finance Accounting and Economic TheoryTransylvania UniversityBrasovRomania

This scientific approach mainly aims to develop a smart city/smart community concept to objectively evaluate the progress of these organizational forms in relation to other classical/traditional forms of city *** elaborated model allowed the construction of the dashboard of access actions in the smart city/smart community category on two levels of financial effort correlated with the effect on the sustainable development of smart *** validity of the proposed model and our approach was supported by the complex statistical analysis performed in this *** research concluded that low-cost solutions are the most effective in supporting smart urban *** should be followed by the other category of solutions,which implies more significant financial and managerial efforts as well as a higher rate of welfare growth for urban *** main outcomes of this research include modelling solutions related to smart city development at a low-cost level and identifying the sensitivity elements that maximize the growth *** implications of this research are to provide viable alternatives based on smart city development opportunities with medium and long-term effects on urban communities,economic sustainability,and translation into urban development *** study’s results are useful for all administrations ready for change that want the rapid implementation of the measures with beneficial effects on the community or which,through a strategic vision,aim to connect to the European objectives of sustainable growth and social welfare for ***,this study is a tool for defining and implementing smart public policies at the urban level.

关键词： IoT Smart city Smart economy Sustainability Urban development

Psychological Experience of Mothers of Children with Sickle Cell Disease Followed at the Pediatric Department of Bouaké University Teaching Hospital

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Open Journal of Pediatrics 2024年第1期14卷 149-163页

作者： Akanji Iburaima Alamun Aka-Tanoh Koko Aude Hélène Yao Kouassi Christian Adou Leioh romeo Sahi Gnantin Josette Landryse Amani Ehi Alexise Eleonore Boune Aboulaye Asse Kouadio Vincent Paediatrics Department Bouaké University Teaching Hospital Bouaké C&#244te d’Ivoire

Introduction: Sickle cell disease has physical and emotional repercussions on the child and his family. The aim of this study was to describe the psychosocial experiences of mothers of children with sickle cell disease in order to improve the overall care of the child. Methods: This was a descriptive cross-sectional study carried out in the pediatrics department of Bouaké University Teaching Hospital from June to September 2023. It focused on mothers of major sickle-cell-affected children followed up in the pediatrics department of the Bouaké University Teaching Hospital. The variables studied were sociodemographic, psychological, social and economic. Results: Of the 40 mothers surveyed, 15% were not in school and 32.5% were unemployed. For them, sickle cell disease was of natural (genetic) origin in 90% and supernatural in 10%. They stated that the child had an average age of 36 months (extremes 7 and 108 months) when the disease was discovered. And 52% of them were satisfied with the way the disease was clearly and completely announced. Following the announcement, the questioned mothers said they had felt shock (35%), sadness (31.7%), guilt (23.3%) and discouragement (10%). Anxiety and depression were experienced by 77.5% and 22.5% respectively. In 60% of cases, they stated that the disease was incurable, and the outcome was fatal in 2.5% of cases. The child’s illness was a source of problems in the home in 25% of cases, represented by arguments in 92% and divorce in 8%. In 97.5% of cases, the mother told her family and friends about the child’s illness. In 90% of cases, the mother and child benefited from psychological support from family and friends. Conclusion: Sickle cell disease is a serious illness with a psychological and social impact on mothers. We recommend psychological support for mothers from the moment of diagnosis and throughout follow-up.

关键词： Psychosocial Experience Sickle Cell Disease Côte d’Ivoire

复合型髋臼骨折围手术期多次静脉使用氨甲环酸的有效性及安全性评价

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华西医学 2024年第3期39卷 461-467页

作者：余游邹昌谭鹏 Guy romeo Kenmegne 尹一杰黄申博何帅方跃四川大学华西医院骨科/创伤医学中心成都610041

目的探讨复合型髋臼骨折围手术期多次静脉使用氨甲环酸(tranexamic acid,TXA)减少失血的有效性和安全性。方法选择2021年9月—2022年12月四川大学华西医院骨科/创伤医学中心收治的复合型髋臼骨折拟行手术患者。按照TXA的不同使用方案,... 详细信息

目的探讨复合型髋臼骨折围手术期多次静脉使用氨甲环酸(tranexamic acid,TXA)减少失血的有效性和安全性。方法选择2021年9月—2022年12月四川大学华西医院骨科/创伤医学中心收治的复合型髋臼骨折拟行手术患者。按照TXA的不同使用方案,采用随机数字表法随机将纳入患者分为对照组和试验组。观察纳入患者的一般资料、总失血量、术后48 h引流量、隐性失血量、纤溶指标、输血率及静脉血栓事件发生率。结果共纳入患者60例,其中男41例,女19例;每组各30例。两组患者的性别、年龄、体质量指数、手术入路及手术时长比较,差异均无统计学意义(P>0.05)。对照组和试验组的总失血量[(795.90±451.36)vs.(579.70±315.88)mL]、术后48 h引流量[(231.33±130.77)vs.(147.67±73.14)mL]、隐性失血量[(406.23±356.17)vs.(170.30±163.75)mL]、输血率(63.3%vs.36.7%)比较,差异均有统计学意义(P0.05)。所有患者术后均未发生肺栓塞。两组的血红蛋白、红细胞压积均随时间下降(P0.05)。两组的纤维蛋白原、D-二聚体呈现不同变化趋势(P<0.05),且试验组优于对照组。结论对于复合型髋臼骨折围手术期多次静脉使用TXA能有效减少患者总失血量、隐性失血量,减少围手术期输血率,且不增加静脉血栓性疾病发生。

关键词：复合型髋臼骨折围手术期多次静脉氨甲环酸有效性及安全性

Effect of shifting cultivation and fallow on soil quality index in Mokokchung district,Nagaland,India

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Ecological Processes 2022年第1期11卷 561-576页

作者： Wati Temjen Maibam romeo Singh Tali Ajungla Department of Botany Nagaland University798627 LumamiIndia Centre for Biodiversity Department of BotanyNagaland University798627 LumamiIndia

Background:Shifting cultivation is a major agriculture practice in the Nagaland state of *** study examines the effect of shifting cultivation and the length of the fallow period on soil quality index(SQI).Four sites were selected for the study,viz.,a shifting cultivation site(SCS),a 3-year-old fallow land(FL-3),a 7-year-old fallow land(FL-7),and a 12-year-old fallow land(FL-12).Soil parameters were recorded seasonally and SQI was calculated from the minimum data ***:With the increase in the fallow period,the values of conductivity,soil organic carbon,available nitrogen,available phosphorus,exchangeable potassium,moisture,clay,and cation exchange capacity of soil ***,soil pH and bulk density decreased with fallow *** additive SQI_(a)values were in the order SCS

关键词： Shifting cultivation Jhum Soil quality index Soil health Seasonal variation Nagaland India

Clinical relevance of stem cells in lung cancer

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World Journal of Stem Cells 2023年第6期15卷 576-587页

作者： Horacio Eduardo romeo María Laura Barreiro Arcos School of Engineering and Agrarian Sciences Pontifical Catholic University of ArgentinaInstitute of Biomedical Research(BIOMED-UCA-CONICET)CABA C1107AAZBuenos AiresArgentina

Lung cancer is the major cause of cancer-related deaths worldwide,it has one of the lowest 5-year survival rate,mainly because it is diagnosed in the late stage of the *** cancer is classified into two groups,small cell lung cancer(SCLC)and non-SCLC(NSCLC).In turn,NSCLC is categorized into three distinct cell subtypes:Adenocarcinoma,squamous cell carcinoma,and large cell *** is the most common lung cancer,accounting for 85%of all lung *** for lung cancer is linked to the cell type and stage of the disease,involving chemotherapy,radiation therapy,and *** improvements in therapeutic treatments,lung cancer patients show high rates of recurrence,metastasis,and resistance to *** stem cells(SCs)are undifferentiated cells capable of self-renewal and proliferation,are resistant to chemotherapy and radiotherapy and,due to their properties,could be involved in the development and progression of lung *** presence of SCs in the lung tissue could be the reason why lung cancer is difficult to *** identification of lung cancer stem cells biomarkers is of interest for precision medicine using new therapeutic agents directed against these cell *** this review,we present the current knowledge on lung SCs and discuss their functional role in the initiation and progression of lung cancer,as well as their role in tumor resistance to chemotherapy.

关键词： Lung cancer Cancer stem cells Biomarkers Chemoresistance

Conservative management of an early abdominal complication during a Tullio percutaneous endoscopic excision of renal pelvis urothelial carcinoma:A case report

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World Journal of Clinical Urology 2024年第1期13卷 1-6页

作者： Massimiliano Bernabei NicolòFabbri Danila romeo Elisa Paiolo Martina Bandi Maurizio Simone Department of Urology Azienda USL di FerraraFerrara 44100Italy Department of Surgery University of FerraraAzienda USL of FerraraAzienda USL of FerraraFerrara 44100FerraraItaly Local Health Agency of Ferrara Ferrara 44100Italy

BACKGROUND Upper tract urothelial carcinoma(UTUC)representing only a small fraction of all urothelial *** predominantly affects the renal pelvis in men,often coexisting with bladder *** displays a more aggressive genetic profile compared to bladder neoplasms,with the majority of patients presenting with advanced ***,about a quarter of UTUC cases exhibit high-grade subtypes,associated with a worse *** use and past exposure to aromatic amines are significant risk factors for *** modalities such as Uro-computed tomography and magnetic resonance imaging play crucial roles in *** is vital for direct visualization and biopsy sampling,but its limited sampling capacity presents challenges in determining tumor depth and ***,nephroureterectomy with bladder cuff excision has been the gold-standard treatment for *** conservative treatment has recently emerged as a viable option for selected patients,offering comparable oncological outcomes to radical *** access is also feasible for larger intrarenal *** SUMMARY We present a case of an 84-year-old woman who underwent percutaneous endoscopic excision of a renal pelvis neoplasm using the Tullio *** successful tumor removal,the patient experienced a postoperative complication with abdominal fluid *** management effectively resolved the *** the patient's age and refusal for radical surgery,the conservative approach proved to be a valid therapeutic *** Overall,UTUC remains a diagnostic and therapeutic challenge due to its ***,advances in endoscopic and percutaneous techniques provide valuable alternatives for selected patients,warranting further exploration in this evolving field.

关键词： Upper tract urothelial carcinoma Endoscopic treatment Damage management Case report