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Chapter 5 Dark Matter and New physics Beyond the Standard Model with LHAASO

Chinese physics C 2022年第3期46卷 126-138页

作者： Xiao-Jun Bi Andrea Addazi Konstantin Belotsky Vitaly Beylin Marco Cirelli Arman Esmaili Nicolao Fornengo Qing-Yu Gan Michael Kachekriess Maxim Khlopov Vladimir Korchagin Alexander Korochkin Vladimir Kuksa Antonino Marciano Andrei Neronov paolo panci roman pasechnick Alexander Sakharov Filippo Sala Giuseppe Di Sciascio Dimiri Semikoz pasquale Dario Serpico Nikolay Volchanskiy peng-Fei Yin Key Laboratory of particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Center for Theoretical physics College of Physics Science and TechnologySichuan UniversityChengdu 610065China Laboratori Nazionali di Frascati INFN Frasacati(Rome)ItalyEU National Research Nuclear University MEpHI(Moscow State Engineering physics Institute) 31 Kashirskoe chausseeMoscow 115409Russia Institute of physics Southern Federal University Stachki 194Rostov on Don 344090Russia LpTHE CNRS and Sorbonne Universit′e4 Place JussieuF-75252ParisFrance Departamento de Fisica Pontificia Universidade Catolica do Rio de JaneiroRio de Janeiro 22452-970Brazil Dipartimento di Fisica Universita di TorinoVia P.Giuria 110125 TorinoItaly Istituto Nazionale di Fisica Nucleare Sezione di TorinoVia P.Giuria 110125TorinoItaly Institutt for fysikk NTNU7491 TrondheimNorway Universite de paris CNRSAstroparticule et CosmologieF-75013 ParisFrance Department of physics and Center for Field Theory and particle physics Fudan UniversityShanghai 200433China Astronomy Department University of GeneveCh.d’Ecogia 161290VersolxSwitzerland Dipartimento di Fisica Universita di Pisa and INFNSezione di Pisa Largo Pontecorvo 356127 PisaItaly Department of Astronomy and Theoretical physics Lund University22100 LundSwedenEU Experimental physics Department CERNGeneva 23 CH 1211Switzerland Department of physics New York UniversityNew York NY United States of America INFN sezione Roma Tor Vergata I-00133 RomeItaly LApTh Univ.Grenoble AlpesUSMBCNRSF-74000 AnnecyFrance Bogoliubov Laboratory of Theoretical pjysics JINRDubnaRussia

In order to reveal the nature of dark matter,it is crucial to detect its non-gravitational interactions with the standard model *** traditional dark matter searches focused on the so-called weakly interacting massive ***,this paradigm is strongly constrained by the null results of current experiments with high *** there is a renewed interest of searches for heavy dark matter particles above TeV *** Large High Altitude Air Shower Observatory(LHAASO)with large effective area and strong background rejection power is very suitable to investigate the gamma-ray signals induced by dark matter annihilation or decay above TeV *** this document,we review the theoretical motivations and background of heavy dark *** review the prospects of searching for the gamma-ray signals resulted from dark matter in the dwarf spheroidal satellites and Galactic halo for LHAASO,and present the projected *** also review the prospects of searching for the axion-like particles,which are a kind of well motivated light pseudo-scalars,through the LHAASO measurement of the very high energy gamma-ray spectra of astrophysical sources.

关键词： dark matter gamma-ray axion-like particle

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Microbial reduction of organosulfur compounds at cathodes in bioelectrochemical systems

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Environmental Science and Ecotechnology 2020年第1期1卷 68-73页

作者： Margo Elzinga Dandan Liu Johannes B.M.Klok pawel roman Cees J.N.Buisman Annemiek ter Heijne Environmental Technology Wageningen UniversityBornse Weilanden 9P.O.Box 176700AA Wageningenthe Netherlands paqell B.V Reactorweg 3013542AD Utrechtthe Netherlands Wetsus Centre of Excellence for Sustainable Water TechnologyOostergoweg 9P.O.Box 11138900CC Leeuwardenthe Netherlands

Organosulfur compounds,present in *** pulp and paper industry,biogas and natural gas,need to be removed as they potentially affect human health and harm the *** treatment of organosulfur compounds is a challenge,as an economically feasible technology is *** this study,we demonstrate that organosulfur compounds can be degraded to sulfide in bioelectrochemical systems(BESs).Methanethiol,ethanethiol,propanethiol and dimethyl disulfide were supplied separately to the biocathodes of BESs,which were controlled at a constant current density of 2 A/m^(2) and 4 A/m^(2).The decrease of methanethiol in the gas phase was correlated to the increase of dissolved sulfide in the liquid phase.A sulfur recovery,as sulfide,of 64% was found over 5 days with an addition of 0.1 mM *** recoveries over 22 days with a total organosulfur compound addition of 1.85 mM were 18% for methanethiol and ethanethiol,17% for propanethiol and 22% for dimethyl *** sulfide was formed in electrochemical nor biological control experiments,demonstrating that both current and microorganisms are required for the conversion of organosulfur *** new application of BES for degradation of organosulfur components may unlock alternative strategies for the abatement of anthropogenic organosulfur emissions.

关键词： Thiols Organosulfur compounds Bioelectrochemical system

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High-speed identification of suspended carbon nanotubes using Raman spectroscopy and deep learning

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Microsystems & Nanoengineering 2022年第1期8卷 259-267页

作者： Jian Zhang Mickael L.perrin Luis Barba Jan Overbeck Seoho Jung Brock Grassy Aryan Agal Rico Muff Rolf Brönnimann Miroslav Haluska Cosmin roman Christofer Hierold Martin Jaggi Michel Calame Laboratory for Transport at Nanoscale Interfaces EmpaSwiss Federal Laboratories for Materials Science and TechnologyCH-8600 DübendorfSwitzerland Machine Learning and Optimization Laboratory School of Computer and Communication SciencesEPFLCH-1015 LausanneSwitzerland Department of physics and Swiss Nanoscience Institute University of BaselCH-4056 BaselSwitzerland Micro-and Nanosystems Department of Mechanical and Process EngineeringETH ZurichCH-8092 ZurichSwitzerland

The identification of nanomaterials with the properties required for energy-efficient electronic systems is usually a tedious human task.A workflow to rapidly localize and characterize nanomaterials at the various stages of their integration into large-scale fabrication processes is essential for quality control and,ultimately,their industrial *** this work,we develop a high-throughput approach to rapidly identify suspended carbon nanotubes(CNTs)by using high-speed Raman imaging and deep learning *** for Raman spectra with extremely low signal-to-noise ratios(SNRs)of 0.9,we achieve a classification accuracy that exceeds 90%,while it reaches 98%for an SNR of *** applying a threshold on the output of the softmax layer of an optimized convolutional neural network(CNN),we further increase the accuracy of the ***,we propose an optimized Raman scanning strategy to minimize the acquisition time while simultaneously identifying the position,amount,and metallicity of CNTs on each *** approach can readily be extended to other types of nanomaterials and has the potential to be integrated into a production line to monitor the quality and properties of nanomaterials during fabrication.

关键词： carbon suspended speed

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Hereditary Immunity and the Origin of Atherosclerosis

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Open Journal of Immunology 2014年第1期4卷 14-21页

作者： Sergey N. Rumyantsev Vil K. Gerasimov Jergy Grzezczuk roman A. Aron Nataly F. Avrova Irina V. Belyakova Ludmila V. Bobrakova Kirill F. Dubrov Ludmila V. perkus Vladimir F. pospelov Nina M. Rogacheva Nikolay p. Shabalov Department of Evolutionary Immunology Andent Inc. Jersey City USA

This paper tries to present new confirmation for the opinion about the infectious origin of atherosclerosis from the viewpoint of the current knowledge of hereditary immunity. The performed integrative investigation included the reinterpretation of known clinical and epidemiological observations, supported by immunological, molecular ecological, genetic, and genomic discoveries. The revealed body of firstly achieved information is compatible with the concept that infectious agents contribute the clue step to the development of atherosclerosis over its initial stage performed during the triggering of the arterial endothelial wall by the molecular agent of proposed infectious origin.

关键词： Epidemic Spread Heterozygosity Homozygosity Immune Mosaicism Integrative Approach plaque Formation

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逆流色谱法分离纯化蒲公英中多酚类化合物

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山东科学 2022年第6期35卷 1-7页

作者：高洁宋祥云马天宇刘峰 roman Kachan 王晓齐鲁工业大学(山东省科学院)山东省分析测试中心山东济南250014 齐鲁工业大学(山东科学院)基辅学院山东济南250353 基辅国立工艺设计大学乌克兰基辅01011

采用pH区带逆流色谱(pH-zone-refining counter-current chromatography, pH-ZRCCC)与高速逆流色谱(high-speed counter-current chromatography,HSCCC)相结合的方式,从蒲公英中分离得到6个多酚类化合物。在pH-ZRCCC分离中,选择溶剂体系为乙酸乙酯-乙腈-水(体积比4:1:5),上相加入三氟乙酸(10 mmol/L)作为固定相,下相加入氨水(10 mmol/L)作为流动相。从1.6 g蒲公英乙酸乙酯粗提物中分离得到咖啡酸(60.2 mg,纯度98.1%)和对羟基肉桂酸(6.3 mg,纯度98.8%)及混合物A(590 mg)。之后进一步利用HSCCC,选择溶剂体系为石油醚-乙酸乙酯-甲醇-水(体积比1:4:1:4)。从400 mg混合物A中分离得到1-O-咖啡酰基甘油(7.7 mg,纯度82.2%)、3,4-二羟基苯乙酸(5.4 mg,纯度24.8%)、原儿茶酸(6.2 mg,纯度95.3%)以及对羟基苯乙酸(3.4 mg,纯度89.0%)。该方法制备量大,重现性好,适合蒲公英多酚类化合物的分离纯化。

关键词：蒲公英多酚高速逆流色谱 pH区带逆流色谱分离纯化

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An Unusual presentation of Aortic Dissection and Aneurysmatic Disease in Marfan Syndrome: A Case Report

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World Journal of Cardiovascular Diseases 2022年第6期12卷 297-303页

作者： Adrian Espejel-Guzman Valente Fernandez-Badillo Javier Serrano-roman Enrique Solorzano-pinot Sergio Criales-Vera Maria Del Carmen Lopez-Rodriguez Candace Keirns Daniel Zagal-Cardoso Nilda Espinola-Zavaleta Department of Nuclear Cardiology National Institute of Cardiology Ignacio Chavez Mexico City Mexico Department of Computed Tomography National Institute of Cardiology Ignacio Chavez Mexico City Mexico Department of Clinical Cardiology National Institute of Cardiology Ignacio Chavez Mexico City Mexico Shelby County Health Department Memphis TN USA Department of Echocardiography ABC Medical Center I.A.P. Mexico City Mexico

Marfan’s syndrome (MFS) is an autosomal dominant disorder characterized by aortic root dilation, mitral valve prolapse and aortic regurgitation. The typical aneurysm location involves the thoracic aorta (60%). Thoracoabdominal aortic dissections are quite infrequent (10%). A type A aortic dissection can have fatal complications, such as aortic rupture and cardiac tamponade, and a prompt diagnosis is crucial. The present case involves a 46-year-old patient with Marfan’s syndrome who was admitted to the emergency department for dyspnea. The patient presented congestive signs and manifestations suggesting acute heart failure. An initial transthoracic echocardiogram (TTE) showed ventricular hypertrophy and diastolic dysfunction. Additionally, TTE showed plurivalvular regurgitation, pulmonary hypertension (42 mmHg), aortic dilatation, and a dissection flap. Coronary computed tomography angiography (CCTA) was performed, confirming the suspicion of ascending aortic dissection. The patient underwent a three-stage intervention for the repair of all the defects, with adequate recovery. This was a rare presentation of aortic dissection in MFS, which was a diagnostic challenge for the heart team.

关键词： Marfan-Syndrome Aortic-Dissection Heart-Failure

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冰川之城采尔马特群山合抱的瑞士仙境

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环球人文地理 2023年第17期 142-152页

作者：了凡 Thomas schame87 Gerd Gudrun davidyoung11111 ARochau makasana photo yusev kunchainub Cristian Andriana Gorilla saiko3p roman Babakin vitaliymateha

瑞士被人们称为“世间仙境”“上帝的后花园”。小镇采尔马特，可以说是瑞士的缩影，滑雪、登山，冰川、雪色，童话故事里的模样，在这里通通再现……说起世间浑然天成的美景，采尔马特绝对要占据一席之地。采尔马特位于瑞士西南方的瓦...

瑞士被人们称为“世间仙境”“上帝的后花园”。小镇采尔马特，可以说是瑞士的缩影，滑雪、登山，冰川、雪色，童话故事里的模样，在这里通通再现……说起世间浑然天成的美景，采尔马特绝对要占据一席之地。采尔马特位于瑞士西南方的瓦莱州，地属马特洪峰区。这座位于马特洪峰山脚的小镇，为人们再现了童话中的冰雪世界，是著名的冰川之城。

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CD36 genetic variation, fat intake and liver fibrosis in chronic hepatitis C virus infection

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World Journal of Hepatology 2016年第25期8卷 1067-1074页

作者： Omar Ramos-Lopez Sonia roman Erika Martinez-Lopez Nora A Fierro Karina Gonzalez-Aldaco Alexis Jose-Abrego Arturo panduro Department of Molecular Biology in Medicine Civil Hospital of Guadalajara "Fray Antonio Alcalde" Health Sciences University Center University of Guadalajara

AIM To analyze the association of the CD36 polymorphism(rs1761667) with dietary intake and liver fibrosis(LF) in chronic hepatitis C(CHC) patients. METHODS In this study, 73 patients with CHC were recruited. The CD36 genotype(G > A) was determined by a TaqM an real-time pCR system. Dietary assessment was carried out using a three-day food record to register the daily intake of macronutrients. Serum lipids and liver enzymes were measured by a dry chemistry assay. LF evaluated by transient elastography(Fibroscan~)and ApRI score was classified as mild LF(F1-F2) and advanced LF(F3-F4).RESULTS Overall, the CD36 genotypic frequencies were AA(30.1%), AG(54.8%), and GG(15.1%), whereas the allelic A and G frequencies were 57.5% and 42.5%, respectively. CHC patients who were carriers of the CD36 AA genotype had a higher intake of calories attributable to total fat and saturated fatty acids than those with the non-AA genotypes. Additionally, aspartate aminotransferase(AST) serum values were higher in AA genotype carriers compared to non-AA carriers(91.7 IU/L vs 69.8 IU/L, p = 0.02). Moreover, the AA genotype was associated with an increase of 30.23 IU/L of AST(β = 30.23, 95%CI: 9.0-51.46, p = 0.006). Likewise, the AA genotype was associated with advanced LF compared to the AG(OR = 3.60, 95%CI: 1.16-11.15, p = 0.02) or AG + GG genotypes(OR = 3.52, 95%CI: 1.18-10.45, p = 0.02).CONCLUSION This study suggests that the CD36(rs1761667) AA genotype is associated with higher fat intake and more instances of advanced LF in CHC patients.

关键词： Hepatitis C virus infection CD36 receptor Lipids Liver fibrosis Mexico

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Quantum Supercurrent Transistors in Silicon Quantum Wells Confined by Superconductor Barriers

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Journal of Modern physics 2011年第4期2卷 256-273页

作者： Nikolay T. Bagraev Edward Yu. Danilovsky Leonid E. Klyachkin Andrei A. Kudryavtsev roman V. Kuzmin Anna M. Malyarenko Wolfgang Gehlhoff Vladimir V. romanov 不详

We present the findings of spin-dependent single-hole and pair-hole transport in plane and across the p-type high mobility silicon quantum wells (Si-QW), 2 nm, confined by the superconductor δ-barriers on the n-type Si (100) surface. The oscillations of the conductance in normal state and the zero-resistance supercurrent in superconductor state as a function of the top gate voltage are found to be correlated by on- and off-resonance tuning the two-dimensional levels of holes in Si-QW with the Fermi energy in the superconductor δ-barriers. The SIMS and STM studies have shown that the δ-barriers heavily doped with boron, 5 × 1021 cm–3, represent really alternating arrays of silicon empty and doped dots, with dimensions restricted to 2 nm. This concentration of boron seems to indicate that each doped dot located between empty dots contains two impurity atoms of boron. The EpR studies show that these boron pairs are the trigonal dipole centres, B+ - B–, that contain the pairs of holes, which result from the negative -U reconstruction of the shallow boron acceptors, 2B0 => B+ - B–. The electrical resistivity, magnetic susceptibility and specific heat measurements demonstrate that the high density of holes in the Si-QW (> 1011 cm–2) gives rise to the high temperature superconductor properties for the δ-barriers. The value of the superconductor energy gap obtained is in a good agreement with the data derived from the oscillations of the conductance in normal state and of the zero-resistance supercurrent in superconductor state as a function of the bias voltage. These oscillations appear to be correlated by on- and off-resonance tuning the two-dimensional subbands of holes with the Fermi energy in the superconductor δ-barriers. Finally, the proximity effect in the S-Si-QW-S structure is revealed by the findings of the quantization of the supercurrent and the multiple Andreev reflection (MAR) observed both across and along the Si-QW plane thereby identifying the spin transis

关键词： Silicon Quantum Well Superconductor δ-barrier ESR Dipole Boron Center Multiple Andreev Reflection Supercurrent Conductance EDESR Silicon Microcavity

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3胎妊娠者的预防性宫颈环扎术处理

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世界核心医学期刊文摘（妇产科学分册） 2006年第1期2卷 27-28页

作者： Rebarber A. roman A. S. Istwan N. 杨晓梅(译) Dr. A. Rebarber Division of Maternal-Fetal Medicine Department of Ob-stetrics and Gynecology NYU School of Medicine New York NY United States 不详

The purpose of this study was to determine if prophylactic cerclage improves pregnancy outcome in women with triplet pregnancies without a history of cervical insufficiency. Study design: Triplet pregnancies with ≥ 1 day of outpatient surveillance beginning before 32 weeks’ gestation were identified from a database of women in the US who received outpatient preterm labor surveillance services between January 1990 and May 2004. Triplet pregnancies managed with prophylactic cerclage were compared with triplet pregnancies in which cerclage was not placed. patients with a diagnosis of cervical insufficiency in a previous or in the index pregnancy were excluded from analysis. The primary outcome was incidence of preterm birth before 32 weeks. Groups were compared using Fisher exact test, and Student t test with 2- sided p values plet pregnancies met criteria for inclusion, of which 248 women (7.6% ) received prophylactic cerclage. No significant differences were seen in mean gestational age at delivery, incidence of preterm birth before 32 weeks, birth weight, or neonatal days in the hospital. This study had 80% power to detect a 30% reduction in the primary outcome. Conclusion: prophylactic cerclage did not result in improved pregnancy or neonatal outcomes in triplet pregnancies without a history of cervical insufficiency.

关键词：宫颈环扎术妊娠结局预防性妊娠妇女统计学分析新生儿结局功能不全门诊监测宫颈闭锁 Fisher

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