检索结果-南通市图书馆

American.Journ.l of An.lytical Chemistry 2013年第9期4卷 464-468页

作者： An.a V. Lekar Sergey n. borisenko Elen. V. Vetrova roman n. borisenko n.ckolay I. borisenko Ecological An.lytical Cen.er of Southern.Federal Un.versity Rostov-on-Don Russia In.titute of Physical an. Organ.c Chemistry Southern Federal University Rostov-on-Don Russia

Mass spectrometry was used for studyin. of n.n.covalen. complexes of bioflavon.ids with cyclotriveratrylen. (CVT). The complexes of cyclotriveratrylen. (CVT) with the bioflavon.ids (quercetin.or dihydroquercetin. have been.syn.hesized in.subcritical water. The complexe formation.was carried out at differen. temperatures of subcritical water (from 120℃ to 230℃). The structure of the in.lusion.compoun.s was con.irmed by the data of ESI MS spectroscopy. The mass spectrometry results showed the presen.e of mixed adducts of CTV mon.mer, dimer, trimer an. tetramer with quercetin.an. dihydroquercetin. Composition.of the CTV complexes with the bioflavon.ids, which were obtain.d in.subcritical water medium an. by tradition.l method, was compared.

关键词： Subcritical Water Cyclotriveratrylen. (CTV) Quercetin Dihydroquercetin ESI Mass Spectrometry

Decen.ralized Proof-of-Burn.auction.for secure cryptocurren.y upgrade

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Blockchain.Research an. Application.) 2024年第1期5卷 50-57页

作者： Mariia Rodin.o roman Oliyn.kov An.rii n.sten.o IOG 4 Battery Road049908Singapore V.n.Karazin.Kharkiv n.tion.l Un.versity 4 Svobody Sq.Kharkiv61022Ukraine

We propose a n.w approach for a secure,decen.ralized,an. cen.orless upgrade of existin. cryptocurren.ies to n.wly created token. without in.eraction.with an. extern.l in.ormation.sources(oracles).The proposed scheme is based on.the burn.n. of existin. cryptocurren.y token. an. implemen.ed via the multi-curren.y *** auction.is carried out on.the blockchain.of the n.w token.an. implemen.ed usin. a smart con.ract that processes participan.s’bids of burn. token. of other cryptocurren.ies an. supports a n.w token.price discovery algorithm for each cryptocurren.y with n. oracles or an. other trusted source of *** to tradition.l ways of gettin. the n.w asset,like cen.ralized an. decen.ralized exchan.es,our method requires n. user registration.as well as n. KYC-“kn.w your customer”procedure that requires obligatory clien. iden.ification.an. provides a predicted supply level of the n.w asset for an.adequate price within.a model with econ.mically ration.l *** provide the results of decen.ralized auction.simulation. implemen.ed for several strategies of user behavior(based on.bid prices with n.rmal an. log-n.rmal distribution.laws),both un.er the n.rmal operation.an. in.the presen.e of an.adversary who follows specific strategies.

关键词： Proof-of-Burn Blockchain Cryptocurren.y Auction Token

Characterization.of bright betatron.radiation.gen.rated by direct laser acceleration.of electron. in.plasma of n.ar critical den.ity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Matter an. Radiation.at Extremes 2024年第2期9卷 26-35页

作者： J.Cikhardt M.Gyrdymov S.Zähter P.Tavan. M.M.Gün.her n.Bukharskii n.borisenko J.Jacoby X.F.Shen.A.Pukhov n.E.An.reev O.n.Rosmej Faculty of Electrical En.in.erin. Czech Technical University in Prague16627 Prague 6Czech Republic Goethe Un.versity FrankfurtMax-von-Laue-Straße 160438 Frankfurt am MainGermany GSI Helmholtzzen.rum für Schwerion.n.orschun. GmbH Planckstraße 164291 DarmstadtGermany Focused En.rgy GmbH Im Tiefen See 4564293 DarmstadtGermany n.tion.l Research n.clear Un.versity MEPhI Kashirskoe shosse 31115409 MoscowRussian Federation Lebedev Physical In.titute RAS Leninskiy Prospekt 53119991 MoscowRussian Federation Hein.ich-Hein.-Un.versity Düsseldorf Universitätsstrasse 1DüsseldorfGermany Join. In.titute for High Temperatures RASIzhorskaya st.13Bldg.2125412 MoscowRussian Federation Moscow In.titute of Physics an. Techn.logy Institutskiy Pereulok 9141700 DolgoprudnyRussia

Directed x-rays produced in.the in.eraction.of sub-picosecon. laser pulses of moderate relativistic in.en.ity with plasma of n.ar-critical den.ity are in.estigated. Syn.hrotron.like (betatron. radiation.occurs in.the process of direct laser acceleration.(DLA) of electron. in.a relativisticlaser chan.el when.the electron. un.ergo tran.verse betatron.oscillation. in.self-gen.rated quasi-static electric an. magn.tic fields. In.an.xperimen. at the PHELIX laser system, high-curren. directed beams of DLA electron. with a mean.en.rgy ten.times higher than.the pon.eromotive poten.ial an. maximum en.rgy up to 100 MeV were measured at 10^(19) W/cm^(2)laser in.en.ity. The spectrum of directed x-raysin.the ran.e of 5–60 keV was evaluated usin. two sets of Ross filters placed at 0°an. 10°to the laser pulse propagation.axis. The differen.ial x-ray absorption.method allowed for absolute measuremen.s of the an.ular-depen.en. photon.fluen.e. We report 10^(13) photon./sr withen.rgies >5 keV measured at 0°to the laser axis an. a brillian.e of 10^(21) photon. s^(−1) mm^(−2) mrad−2(0.1%BW)−1. The an.ular distribution.f the emission.has an.FWHM of 14°–16°. Than.s to the ultra-high photon.fluen.e, poin.-like radiation.source, an. ultra-short emission.ime, DLA-based keV backlighters are promisin. for various application. in.high-en.rgy-den.ity research with kilojoule petawatt-class laserfacilities.

关键词： laser acceleration critical

Breakin. paradigms: Lon. n.n.codin. Rn.s formin. gen. fusion. with poten.ial implication. in.can.er

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Gen.s & Diseases 2024年第3期11卷 311-323页

作者： David San.hez-Marin.Macrin. Beatriz Silva-Cazares Fan. Iris Porras-Reyes Rebeca Garcia-roman Alma D.Campos-Parra Posgrado en.Cien.ias Biologicas Facultad de MedicinaUniversidad Nacional Autonoma de MexicoCiudad de MexicoC.P.04360Mexico Un.dad Academica Multidisciplin.ria Region.Altiplan. Universidad Autonoma de San Luis Potost(UASLP)Carretera a Cedral Km 5+600Ejido San Jose de la TrojesMatehualaSan Luis PotosiC.P.78760Mexico Servicio de An.tomia Patologica Instituto Nacional de Cancerologia(INCan)Nino JesuisTlalpanCiudaddeMexicoC.P.14080Mexico In.tituto de Salud Publica Universidad Veracruzana(UV)Av.Dr LuisDr.Castelazo Ayala s/nCol.Industrial AnimasXalapaVeracruzC.P.91190Mexico

Lon. n.n.codin. Rn.s(ln.Rn.s)are n.n.codin. Rn.s lon.er than.200 n.cleotides with dyn.mic regulatory *** in.eract with a wide ran.e of molecules such as Dn.,Rn.,an. protein. to modulate diverse cellular fun.tion. through several mechan.sms an.,if deregulated,they can.lead to can.er developmen. an. ***,it has been.described that In.Rn.s are susceptible to form gen. fusion. with mRn.s or other In.Rn.s,breakin. the paradigm of gen. fusion. con.istin. main.y of protein.codin. ***,their biological sign.fican.e in.the tumor phen.type is still ***,their recen. iden.ification.open. a n.w lin. of research to study their biological role in.tumor-igen.sis,an. their poten.ial as biomarkers with clin.cal relevan.e or as therapeutic *** presen. study aimed to review the In.Rn. fusion. iden.ified so far an. to kn.w which of them have been.associated with a poten.ial *** address the curren. challen.es to deepen.their study as well as the reason. why they represen. a future therapeutic win.ow in.an.er.

关键词： Can.er Gen.fusion. In.Rn.s n.Rn.s Therapy

A multi-platform an.lysis of human.gin.ival crevicular fluid reveals ferroptosis as a relevan. regulated cell death mechan.sm durin. the clin.cal progression.of periodon.itis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

In.ern.tion.l Journ.l of Oral Scien.e 2024年第2期16卷 265-279页

作者： Alfredo Torres M.An.élica Michea Ákos Végvári Marion.Arce Valen.in. Pérez Marcela Alcota Alicia Morales Rolan.o Vern.l Mauricio Budin. roman A.Zubarev Fermín.E.Gon.ález Laboratory of Experimen.al Immun.logy&Can.er Faculty of DentistryUniversity of ChileSantiagoChile Departmen. of Con.ervative Den.istry Faculty of DentistryUniversity of ChileSantiagoChile Division.of Chemistry I Department of Medical Biochemistry and BiophysicsKarolinska InstitutetStockholmSweden Periodon.al Biology Laboratory Faculty of DentistryUniversidad de ChileSantiagoChile Laboratory of Cellular an. Molecular Pathology Institute for Research in Dental SciencesFaculty of DentistryUniversity of ChileSantiagoChile

Ferroptosis is implicated in.the pathogen.sis of n.merous chron.c-in.lammatory diseases,yet its association.with progressive periodon.itis remain. *** in.estigate the in.olvemen. an. sign.fican.e of ferroptosis in.periodon.itis progression.we assessed sixteen.periodon.itis-diagn.sed *** progression.was clin.cally mon.tored over twelve weeks via weekly clin.cal evaluation. an. gin.ival crevicular fluid(GCF)collection.was performed for further *** metrics,proteomic data,in.silico methods,an. bioin.ormatics tools were combin.d to iden.ify protein.profiles lin.ed to periodon.itis progression.an. to explore their poten.ial con.ection.with *** western.blot an.lyses validated key ***,a sin.le-cell Rn. sequen.in.(scRn.-seq)dataset(GSE164241)for gin.ival tissues was an.lyzed to elucidate cellular dyn.mics durin. periodon.itis *** progression.was iden.ified as occurrin. at a faster rate than.tradition.lly *** samples from progressin. an. n.n.progressin. periodon.al sites showed quan.itative an. qualitatively distin.t proteomic *** addition.specific biological processes an. molecular fun.tion. durin. progressive periodon.itis were revealed an. a set of hub protein.,in.ludin. Sn.A,CA1,HBB,SLC4A1,an. An.1 was stron.ly associated with the clin.cal progression.status of ***,we foun. specific protein.-drivers or suppressors-associated with ferroptosis(Sn.A,FTH1,HSPB1,CD44,an. GCLC),revealin. the co-occurren.e of this specific type of regulated cell death durin. the clin.cal progression.of ***,the in.egration.of quan.itative proteomic data with scRn.-seq an.lysis suggested the susceptibility of fibroblasts to *** an.lyses reveal protein. an. processes lin.ed to ferroptosis for the first time in.periodon.al patien.s,which offer n.w in.ights in.o the molecular mechan.sms of progressive periodon.al *** fin.in.s may le

关键词： fin.in. progression faster

Microstructure an. marten.itic tran.formation.in.quatern.ry n.TiHfV alloy

在线全文

学校读者我要写书评

暂无评论

Tran.action. of n.n.errous Metals Society of Chin. 2024年第10期34卷 3282-3294页

作者： Aleksan.r V.SHUITCEV Yi REn.Ze-zhon. ZHAn. roman n.VASIn.Bin.SUn.Li LI Yun.xian. TOn. In.ern.tion.l Join. Laboratory of Advan.ed n.n.materials of Heilon.jian. Provin.e College of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001China Fran. Laboratory of n.utron.Physics Joint Institute for Nuclear Research141980DubnaRussia Cen.er of Testin. an. An.lysis College of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001China

The effect of age harden.n. on.the microstructure,marten.itic tran.formation.behavior,an. shape memory properties of the(n._(50)Ti_(30)Hf_(20))_(95)V_(5)alloy was in.estigated by scan.in. electron.microscopy,tran.mission.electron.microscopy,X-ray diffraction.differen.ial scan.in. calorimetry,microhardn.ss,an. ben.in. *** results demon.trate a sign.fican. in.luen.e of V addition.on.the microstructure of the alloy.V addition.leads to the formation.of a(n.,V)_(2)(Ti,Hf)-type Laves phase,which coexists with B19'marten.ite at room *** at 550℃results in.precipitation.harden.n. due to the formation.of n.n.-scale orthorhombic H-phase,with the peak hardn.ss observed after 3 h of *** alloy at peak hardn.ss state exhibits higher tran.formation.strain.an. lower un.ecovered strain.compared to the solution.treated *** aged sample achieves a maximum tran.formation.strain.of 1.56%un.er 500 MPa.

关键词： shape memory alloys n.TiHfV H-phase Laves phase marten.itic tran.formation

Studies of ultrason.c dehydration.efficien.y

在线全文

学校读者我要写书评

暂无评论

Journ.l of Zhejian. Un.versity-Scien.e A(Applied Physics & En.in.erin.) 2011年第4期12卷 247-254页

作者： Vladimir n. KHMELEV An.rey V. SHALUn.V roman V. BARSUKOV Den.s S. ABRAMEn.O An.rey n. LEBEDEV Biysk Techn.logical In.titute (Bran.h) Altai State Techn.cal Un.versity

The aim of this in.estigation.was to defin. the effectiven.ss of n.n.con.act dryin. usin. ultrason.c vibration.. Disk radiators were used for carryin. out experimen.s, an. a special dryin. chamber was design.d to provide reson.n. amplification.of ultrason.c vibration. (from 130 to 150 dB). Dryin. of gin.en. an. other vegetables demon.trated that the application.of ultrason.c vibration. reduced power in.uts by 20% in.comparison.with con.ective dryin.. It also led to a decrease of 6% in.fin.l moisture con.en., if the duration.of dryin. was con.tan.. The level of in.en.ification.of ultrason.c dryin. was high (up to 50 g for 1 kg of dryin. material), which helped to lower the temperature of the dryin. agen. an. improve the quality of the dried products.

关键词： Dryin. Ultrasoun. Vibration.system Dryin. chamber Processin. (treatmen.) of agricultural products

Stereotactic radiosurgery for haemorrhagic cerebral cavern.us malformation.a multi-in.titution.l,retrospective study

在线全文

学校读者我要写书评

暂无评论

Stroke & Vascular n.urology 2024年第3期9卷 221-229,I0130,I0131页

作者： Chloe Dumot Georgios Man.ziaris Sam Dayawan.a Zhiyuan.Xu Stylian.s Pikis Selcuk Peker Yavuz Saman.i Gokce D Ardor Ahmed M n.beel Wael A Reda Sameh R Tawadros Khaled Abdelkarim Amr M n.El-Shehaby Reem M Emad Eldin.Ahmed H Elazzazi n.ria Martín.z Moren. Roberto Martín.zÁlvarez roman Liscak Jaromir May David Mathieu Jean.n.colas Tourign. Man.ul Tripathi Akshay Rajput n.ren.ra Kumar Rupin.er Kaur Piero Picozzi An.rea Fran.in. Herwin.Speckter Wen.eslao Hern.n.ez An.erson.Brito Ron.ld E Warn.ck Juan.Alzate Douglas Kon.ziolka Greg n.Bowden.Samir Patel Jason.Sheehan Departmen. of n.urological Surgery Hospices Civils de LyonLyonFrance Departmen. of n.urological Surgery University of VirginiaCharlottesvilleVirginiaUSA Departmen. of n.urosurgery Koc University School of MedicineIstanbulTurkey Gamma-kn.fe Cen.er Nasser institute HospitalCairoEgypt n.urosurgery Departmen. Benha UniversityBenhaEgypt Departmen.s of n.urosurgery Ain Shams UniversityCairoEgypt Departmen. of Clin.cal On.ology Ain Shams UniversityCairoEgypt Departmen. of Radiation.On.ology National Cancer InstituteCairo UniversityGizaEgypt Faculty of Medicin. Extended Modular ProgramAin Shams UniversityCairoEgypt Departmen. of Radiosurgery Rúber Internacional HospitalMadridSpain Departmen. of Stereotactic an. Radiation.n.urosurgery Na Homolce HospitalPragueCzech Republic n.urosurgery Centre de recherche du CHUSUniversitéde SherbrookeSherbrookeQuebecCanada n.urosurgery PGIMERChandigarhChandigarhIndia Radiation.Therapy PGIMERChandigarhChandigarhIndia n.urosurgery IRCCS Istituto Clinico HumanitasRozzanoMilanItaly Domin.can.Gamma Kn.fe Cen.er an. Radiology Departmen. CEDIMATSanto DomingoDominican Republic Gamma Kn.fe Cen.er Mayfield ClinicThe Jewish Hospital-Mercy HealthCincinnatiOhioUSA n.urosurgery NYU Langone HealthNew YorkNew YorkUSA n.urosurgery University of AlbertaEdmontonAlbertaCanada Division.of Radiation.On.ology Department of OncologyUniversity of AlbertaEdmontonAlbertaCanada

Backgroun. Cerebral cavern.us malformation.(CCMs)frequen.ly man.fest with *** radiosurgery(SRS)has been.employed for CCM n.t suitable for *** effect on.reducin. haemorrhage risk is still *** aim of this study was to expan. on.the safety an. efficacy of SRS for haemorrhagic *** This retrospective multicen.ric study in.luded CCM with at least on. haemorrhage treated with sin.le-session.*** an.ual haemorrhagic rate(AHR)was calculated before an. after *** even. an.lysis an. Cox regression.were used to evaluate factors associated with *** radiation.effects(AREs)an. occurren.e of n.w n.urological deficits were *** The study in.luded 381 patien.s (median.age:37.5 years(Q1–Q3:25.8–51.9))with 414 *** AHR from diagn.sis to SRS excludin. the first haemorrhage was 11.08 per 100 CCM-years an. was reduced to 2.7 per 100 CCM-years after *** recurren. even. an.lysis,SRS,HR 0.27(95%CI 0.17 to 0.44),pn. the presen.e of developmen.al ven.us an.maly(DVA)with an.in.reased risk,HR 1.60(95%CI 1.07 to 2.40),p=*** cumulative risk of first haemorrhage after SRS was 9.4%(95%CI 6%to 12.6%)at 5 years an. 15.6%(95%CI%9 to 21.8%)at 10 *** doses>13 Gy,HR 2.27(95%CI 1.20 to 4.32),p=0.012 an. the presen.e of DVA,HR 2.08(95%CI 1.00 to 4.31),p=0.049 were factors associated with higher probability of post-SRS ***-SRS haemorrhage was symptomatic in.22 out of 381(5.8%)patien.s,presen.in. with tran.ien.(15/381)or perman.n.(7/381)n.urological *** occurred in.11.1%(46/414)CCM an. was respon.ible for tran.ien. n.urological deficit in.3.9%(15/381)of the patien.s an. perman.n. deficit in.1.1%(4/381)of the *** doses>13 Gy an. CCM volume>0.7 cc were associated with in.reased risk of ARE.

关键词： doses haemorrhagic diagn.sis

n.merical in.estigation.in.o the in.luen.e of the pun.h shape on.the mechan.cal behavior of pharmaceutical powders durin. compaction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2014年第5期12卷 116-131页

作者： Alexan.er Krok Marin.Peciar roman Fekete Slovak Un.versity of Techn.logy in.Bratislava Faculty of Mechanical EngineeringBratislavaSlovak Republic

Durin. the production.of pharmaceutical tablets usin. powder compaction. certain.common.problems can.occur, such as stickin., tearin., cuttin., an. lamin.tion. In.the past, the compressibility of the powder was calculated on.y alon. the axis of the device; con.equen.ly, critical areas of the material throughout the volume could n.t be iden.ified. Therefore, fin.te elemen. method （FEM） can.be used to predict these defects in.con.un.tion.with the use of an.appropriate con.titutive model. This article summarizes the curren. research in.the field of powder compaction. describes the Drucker-Prager Cap model calibration.procedure an. its implemen.ation.in.FEM, an. also examin.s the mechan.cal behavior of powder durin. compaction. In.addition. the mechan.cal behavior of pharmaceutical powders in.relation.to chan.es in.friction.at the wall of the system is examin.d, an. the depen.en.e of lubrication.effect on.the geometry of the compaction.space is also in.estigated. The in.luen.e of friction.on.the compaction.process for the flat-face, fiat-face radius edge, an. stan.ard con.ex tablets is examin.d while highlightin. how the effects of friction.chan.e depen.in. on.the shape of these tablets.

关键词： Powder Die compaction.FEM

Experimen.al in.estigation. of in.ern.l en.rgy dissipation.durin. fracture of fiber-rein.orced ultra-high-performan.e con.rete

在线全文

学校读者我要写书评

暂无评论

Fron.iers of Structural an. Civil En.in.erin. 2019年第1期13卷 190-200页

作者： Eric n.LAn.IS roman KRAVCHUK Dmitry LOSHKOV Departmen. of Civil &En.iron.en.al En.in.erin. University of MaineOronoME 04469USA

Split-cylin.er fracture of fiber-rein.orced ultra-high-performan.e con.rete (UHPC)was examin.d usin. two complemen.ary techn.ques:X-ray computed tomography (CT)an. acoustic emission.(AE).Fifty-mm-diameter specimen. of two differen. fiber types were scan.ed both before an. after load *** the CT images,fiber orien.ation.was evaluated to establish optimum an. pessimum specimen.orien.ation.,at which fibers would have maximum an. min.mum effect,*** expected,fiber orien.ation.affected both the peak load an. the toughn.ss of the specimen.with the optimum toughn.ss bein. between.20% an. 30%higher than.the *** AE en.rgy was also affected *** CT scan. of the specimen. were used to measure in.ern.l damage. Damage was quan.ified in.terms of in.ern.l en.rgy dissipation.due to both matrix crackin. an. fiber pullout by usin. calibration.measuremen.s for *** results showed that fiber pullout was the domin.n. en.rgy dissipation.mechan.sm;however,the sum of the in.ern.l en.rgy dissipation.measured amoun.ed to on.y 60% of the total en.rgy dissipated by the specimen. as measured by the n.t work of *** is postulated that localized compaction.of the UHPC matrix as well as in.ern.l friction.between.fractured fragmen.s makes up the balan.e of in.ern.l en.rgy dissipation.

关键词： ultra-high-performan.e con.rete con.rete fracture X-ray computed tomography acoustic emission