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Predictive Factors of Bladder Tumor Recurrence after Nephro-Ureterectomy for Urothelial Carcinoma

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Journal of Cancer Therapy 2015年第2期6卷 122-128页

作者： John David Rebibo Emeric Lacarrière Francois Xavier Nouhaud Athmane Safsaf romain Caremel Christian Pfister Department of Urology Rouen University Hospital Rouen France

Objectives: To evaluate the incidence of bladder cancer after nephro-ureterectomy (NUT) and determine the potential risk factors of bladder recurrence in patients with upper urinary tract urothelial carcinoma (UUT-UC). Materials and Methods: We retrospectively assessed 37 patients with UUT-UC including a significant follow-up after NUT of 34 months (range 12 - 120 months). The median age of the population was 72 years (range 48 - 83 years). Patients with a previous history of bladder cancer, concomitant diagnosis of bladder tumor and UUT-UC;or a metastatic UUT-UC were excluded from the study. Results: Out of these 37 patients, 17 presented a bladder recurrence within an average time of 12 months (range 3 to 31 months) after the NUT. In 94% of the cases, bladder recurrence occurred within the first 24 months following the NUT. Histological distribution was: 13 Ta tumors (76%), 2 pT1 tumors (11.7%);11 patients had a high stage lesion (76%), whereas 4 patients had a low stage lesion (23.5%). As regards the anatomo-pathological characteristics of the UUT-UC, the supra iliac localization of the tumor is a significant risk factor of bladder recurrence (p = 0.04). Conclusion: Bladder recurrence after NUT occurred frequently and could have possibly been under-estimated. The use of intra-vesical instillation of Mitomycin C after NUT has been recently recommended by the European Association of Urology, but no predictive factors have yet been identified. Early diagnosis of bladder recurrence could certainly have reduced mortality in this patient population.

关键词： Bladder Recurrence Nephro-Ureterectomy Urothelial Carcinoma

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罗曼·罗兰音乐笔记

2020年

作者： (法)罗曼·罗兰(romain Rolland)

来源：南通市图书馆图书评论

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勒索软件的威胁

新发现 2021年第10期 84-88页

作者： romain Raffegeau 竹叶(编译) 不详

恶意软件通过挟持并控制计算机来勒索赎金。一次针对医院或配电站等公共服务场所的网络攻击可能将整个社会置于险境。上午10点,刚刚结束第堂课的物理学教授德路易(Deslouis)一走出教室就收到了部门主任发来的邮件:“你能否尽快在学校网... 详细信息

恶意软件通过挟持并控制计算机来勒索赎金。一次针对医院或配电站等公共服务场所的网络攻击可能将整个社会置于险境。上午10点,刚刚结束第堂课的物理学教授德路易(Deslouis)一走出教室就收到了部门主任发来的邮件:“你能否尽快在学校网站上录入学生的成绩?我们准备今晚统计该学期的成绩单。这是网站链接。”

关键词：恶意软件网络攻击网站链接勒索软件物理学教授配电站成绩单计算机

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细菌电池

新发现 2021年第4期 72-74页

作者： romain Raffegeau 葛皓(编译) 不详

细菌可以发电!虽然目前细菌电池应用场景极其有限,但研究人员希望,这一生物能源能很快走出实验室,全面运用于现实生活。生物会发电并不是什么新鲜事。大家都知道某些动物,如电鳗,一次可以释放几百伏特的电。如今,科学家能将某些发电生... 详细信息

细菌可以发电!虽然目前细菌电池应用场景极其有限,但研究人员希望,这一生物能源能很快走出实验室,全面运用于现实生活。生物会发电并不是什么新鲜事。大家都知道某些动物,如电鳗,一次可以释放几百伏特的电。如今,科学家能将某些发电生物放进电池里来生产电流。

关键词：生物能源应用场景实验室现实生活发电电池电流科学家

Determination of Lethal Concentrations Using an R Software Function Integrating the Abbott Correction

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Journal of Agricultural Science and Technology(A) 2017年第1期7卷 25-30页

作者： Merveille Koissi Savi Essomanda Tchandao Mangamana Jean Marcel Deguenon Castro Gbememali Hounmenou romain Glele Kakai Laboratoire de Biomathematiques et d'Estimations Forestieres Faculty of Agronomic Sciences University of Abomey-Calavi 04BP 1525 Cotonou Benin Department of Entomology and Plant Pathology North Carolina State University Campus Box 7616 Raleigh USA

Several thousands of chemical substances are registered every year for different purposes, and sometimes many of them are claimed to play the same role. To establish and compare their toxicities, the determination of the lethal concentrations is usually necessary and should account for natural mortality. However, many of the statistical software packages used for that purpose do not readily integrate control mortality or adjust the best link function to the data during the process. This manuscript proposes an ＂lc＂ function in the R open source that aims at the effective determination of lethal concentrations. Furthermore, it performs the procedure with the appropriate link function. The ＂lc＂ application on the example provided revealed that the complementary log link function is adequate.

关键词： Toxicity lethal concentration Abbott correction binomial family links generalized linear models pesticides.