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Acoustic radiation force impulse imaging for assessing liver fibrosis in alcoholic liver disease

World Journal of Gastroenterology 2016年第20期22卷 4926-4935页

作者： Anita Kiani Vanessa Brun Fabrice Lainé Bruno Turlin Jeff Morcet Sophie Michalak Antonia Le Gruyer Ludivine Legros Edouard Bardou-Jacquet Yves Gandon romain Moirand Department of Abdominal Imaging Rennes University Hospital Clinical Inverstigation Center CIC INSERM 1414 Rennes University Hospital Department of Hepatology Rennes University Hospital Department of Pathology Rennes University Hospital Rennes Department of Pathology Angers University Hospital Department of Addictology Rennes University Hospital Department of Research INSERM UMR 991 Rennes 1 Medicine University

AIM: To evaluate the performance of elastography by ultrasound with acoustic radiation force impulse(ARFI) in determining fibrosis stage in patients with alcoholic liver disease(ALD) undergoing alcoholic detoxification in relation to ***: Eighty-three patients with ALD undergoing detoxification were prospectively enrolled. Each patient underwent ARFI imaging and a liver biopsy onthe same day. Fibrosis was staged according to the METAVIR scoring system. The median of 10 valid ARFI measurements was calculated for each ***: Sixty-nine males and thirteen females(one patient excluded due to insufficient biopsy size) were assessed with a mean alcohol consumption of 132.4 ± 128.8 standard drinks per week and mean cumulative year duration of 17.6 ± 9.5 years. Sensitivity and specificity were respectively 82.4%(0.70-0.95) and 83.3%(0.73-0.94)(AUROC = 0.87) for F ≥ 2 with a cut-off value of 1.63m/s; 82.4%(0.64-1.00) and 78.5%(0.69-0.89)(AUROC = 0.86) for F ≥ 3 with a cut-off value of 1.84m/s; and 92.3%(0.78-1.00] and 81.6%(0.72-0.90)(AUROC = 0.89) for F = 4 with a cut-off value of 1.94 m/***: ARFI is an accurate, non-invasive and easy method for assessing liver fibrosis in patients with ALD undergoing alcoholic detoxification.

关键词： Alcoholic liver disease Elastography Noninvasive Acoustic radiation force impulse Fibrosis

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罗曼·罗兰文钞

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作者： (法)罗曼·罗兰(Rolland romain)

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甘地奋斗史

甘地奋斗史

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1930年

作者：（法）romain Rollanddr原谢济泽译

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Aerodynamics Loads on a Heeled Ship

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Journal of Traffic and Transportation Engineering 2017年第5期5卷 237-245页

作者： romain Luquet Pierre Vonier Jean-Francois Leguen Andrew Prior DGA Hydrodynamics 27105 Val de Reuil France Royal Canadian Navy DGMEPM DNPS 2-3 27105 Val de Reuil France

Verification of ship stability is based on rules which account for the effects of wind. Restrictive hypotheses are employed to define those rules and especially the influence of ship heeling. This study reviews some stability rules and applies them to the case of the F70 frigate. Then, two alternate approaches are considered：（1） accounting for the actual lateral areas and respective centroids of the heeled ship; and （2） CFD （computational fluid dynamics） calculations to determine aero and hydro dynamic coefficients at each heel angle. Finally, comparison is made between the results of these alternate approaches and the stability rules.

关键词： Wind CFD rules naval ships.

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Gastric emptying evaluation by ultrasound prior colonoscopy:An easy tool following bowel preparation

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World Journal of Gastroenterology 2014年第37期20卷 13591-13598页

作者： romain Coriat Vanessa Polin Ammar Oudjit Franck Henri Marion Dhooge Sarah Leblanc Chantal Delchambre Anouk Esch Tessa Tabouret Maximilien Barret Frédéric Prat Stanislas Chaussade Gastroenterology unit and endoscopy unit Université Paris DescartesSorbonne Paris CitéFaculté de MédecineH?pital CochinAssistance Publique?pitaux de Paris (AP-HP) Radiology Department H?pital CochinAssistance Publique-H?pitaux de Paris (AP-HP) Laboratoires Mayoly Spindler

AIM: To investigate the gastric emptying after bowel preparation to allow general anaesthesia.

关键词： Colonoscopy Preparation Ultrasound Gastric emptying

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Obscure bleeding colonic duplication responds to proton pump inhibitor therapy

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World Journal of Gastroenterology 2013年第35期19卷 5940-5942页

作者： Jérémie Jacques Fabrice Projetti romain Legros Virginie Valgueblasse Matthieu Sarabi Paul Carrier Fabien Fredon Stéphane Bouvier Véronique Loustaud-Ratti Denis Sautereau Service d’Hépato-gastro-entérologie CHU Dupuytren

We report the case of a 17-year-old male admitted to our academic hospital with massive rectal *** childhood he had reported recurrent gastrointestinal bleeding and had two exploratory laparotomies 5and 2 years *** emergency abdominal computed tomography scan,gastroscopy and colonoscopy,performed after hemodynamic stabilization,were considered ***-dose intravenous proton pump inhibitor(PPI)therapy was initiated and bleeding stopped *** other massive rectal bleeds occurred 8 h after each cessation of PPI which led to a hemostatic laparotomy after negative gastroscopy and small bowel capsule *** showed long tubular duplication of the right colon,with fresh blood in the duplicated *** lower gastrointestinal bleeding is a difficult medical situation and potentially *** presence of ulcerated ectopic gastric mucosa in the colonic duplication explains the partial efficacy of PPI *** gastrointestinalbleeding responding to empiric anti-acid therapy should probably evoke the diagnosis of bleeding ectopic gastric mucosa such as Meckel’s diverticulum or gastrointestinal duplication,and gastroenterologists should be aware of this potential medical situation.

关键词： Colonic duplication Gastro-intestinal duplication Gastrointestinal bleeding Hemostatic colorectal surgery Proton pump inhibitor therapy

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Kagome Project:Physical and Numerical Modeling Comparison for a Post-formed Elastic Gridshell

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Journal of Civil Engineering and Architecture 2022年第4期16卷 200-226页

作者： Marc Leyral Quentin Chef Tom Bardout romain Antigny Alexis Meyer AMP Research Unit&Laboratory MAP-MAACC ENSA Paris-La Villette144 Avenue de FlandreParis 75019France ENSA Paris-La villette Paris 75019France École Centrale-Supélec Gif-sur-Yvette 91190France

An elastic gridshell is an efficient constructive typology for crossing large spans with little material.A flat elastic grid is built before buckling the structure into shape,in active and post-formed *** design and structural analysis of such a structure requires a stage of form finding that can mainly be done:(1)With a physical model:either by a suspended net method,or an active bending model;(2)With a numerical model performed by dynamic *** these solutions have various biases and assumptions that make them reflect more or less the *** three methods have been applied by Happold and Liddell[1]during the design of the Frei Otto’s Mannheim Gridshell which has allowed us to compare the results,and to highlight the significant differences between digital and physical *** on our own algorithm called ELASTICA[2],our study focuses on:(1)Comparing the results of the ELASTICA’s numerical models to load tests on physical models;(2)The identification of the various factors that can influence the results and explain the observed differences,some of which are then studied;(3)Applying the results to build a full-scale interlaced lattice elastic gridshell based on the Japanese Kagome pattern.

关键词： Interlaced lattice gridshell timber dynamic relaxation numerical modeling physical modeling form finding Kagome.

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Morphological and Molecular Identification of Fungi Associated with Sesame Diseased Plants of the Three Agroclimatic Zones of Burkina Faso

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American Journal of Plant Sciences 2023年第3期14卷 290-307页

作者： Wendolian romain Soalla Pawindé Elisabeth Zida Bouma James Neya Kadidia Koita Laboratoire de Phytopathologie Institut de l’Environnement et de Recherches Agricoles (INERA) Ouagadougou Burkina Faso Laboratoire Biosciences Université Joseph Ki-ZERBO Ouagadougou Burkina Faso

Sesame is Burkina Faso’s second essential agricultural export after cotton. It’s consequently a supply of income for producers and foreign exchange for the country. However, sesame production is characterized by low average yields of about 538 kg·ha-1 at the farmer’s field as compared to the potential yield of the improved varieties (1500 - 2000 kg·ha-1). Fungal diseases are some of the major constraints to sesame production in Burkina Faso. The present study contributes to the development of means to control pathogenic fungi of this crop, which are responsible for significant losses. The objective is to identify the fungi associated with diseased sesame plant samples. To this end, 149 samples of diseased sesame plants were collected from different production sites located in three agro-climatic zones of the country. The analysis of the samples according to the blotting paper method, based on the morphological characteristics of the fungi, allowed the identification of 18 genera with prevalence rates from 2.68% to 97.98%. The most frequently identified genera were Macrophomina (97.98%), Cercospora (86.57%), Fusarium (85.23%), Phoma (62.41%) and Colletotrichum (61.07%). The results also showed a variable distribution of fungi according to the agro-climatic zone with the predominance of Macrophomina in all three zones. Molecular identification by DNA sequencing of 120 isolates belonging to the different fungi detected allowed the identification of 25 species of which the most representative were Macrophomina phaseolina, Cercospora sesami, Corynespora cassiicola, Alternaria simsimi, Alternaria porri, Fusarium oxysporum, F. fujikuroi, F. equiseti, Colletotrichum capsici, and C. gloesporiodes. The present study showed that diseased sesame plants collected from different production sites in Burkina Faso housed several species of fungi. The fungi presence in diseased plants indicates the need to inform and raise the stakeholders’ awareness about the p

关键词： Burkina Faso Fungi Molecular Identification Morphological Identification Sesame

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Combined collision-induced dissociation and photo-selected reaction monitoring mass spectrometry modes for simultaneous analysis of coagulation factors and estrogens

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Journal of Pharmaceutical Analysis 2014年第3期4卷 183-189页

作者： Quentin Enjalbert Marion Girod Jérémy Jeudy Jordane Biarc romain Simon Rodolphe Antoine Philippe Dugourd Jér?me Lemoine Arnaud Salvador Université Lyon 1 CNRS Université de Lyon 69622 Villeurbanne cedexFrance Institut Lumière Matière UMR5306France Institut des Sciences Analytiques UMR 5280France

Oral estrogens are directly associated with changes in plasma levels of coagulation proteins. Thus, the detection of any variation in protein concentrations due to estrogen contraceptives, by a simultaneous analysis of both coagulation proteins and estrogens, would be a very informative tool. In the present study, the merit of photo-selected reaction monitoring （SRM）, a new analytical tool, was evaluated towards estrogens detection in plasma. Then, SRM and photo-SRM detection modes were combined for the simultaneous analysis of estrogen molecules together with heparin co-factor and factor XIIa, two proteins involved in the coagulation cascade. This study shows that photo-SRM could open new multiplexed analytical routes.

关键词： Estrogen Coagulation factorprotein Metabolite Photo-dissociation fragmentation SRM

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米格-25“狐蝠”截击机

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模型世界 2021年第3期 52-63+29页

作者： romain Flechon

1991年1月17日夜间,以美国为首的联军开始对伊拉克发动大规模空袭。"沙漠风暴"行动正式开始。随着各种战略目标被击中,伊拉克战斗机收到指令,争先恐后地升空拦截敌人。午夜时分,Zuhair Dawoud上尉在他座机米格-25PD的雷达上发现了一架F/...

1991年1月17日夜间,以美国为首的联军开始对伊拉克发动大规模空袭。"沙漠风暴"行动正式开始。随着各种战略目标被击中,伊拉克战斗机收到指令,争先恐后地升空拦截敌人。午夜时分,Zuhair Dawoud上尉在他座机米格-25PD的雷达上发现了一架F/A-18,几秒后他扣下扳机,发射了一枚R-40RD导弹。这架"大黄蜂"被这枚大型雷达制导导弹击毁,飞行员Speicher随即战死,这也是联军唯一已知的空对空损失。虽说此事仍然存在争议,但多亏了历史学家,现在我们能够对这场冲突有更多的了解。

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