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Insect Science 2008年第2期15卷 167-178页

作者： Oliver-D. Finch Jorg Loffler roland Pape Carl-von-Ossietzky University of Oldenburg Fk V Institute of Biology and Environmental-Sciences Terrestrial Ecology D-26111 Oldenburg University of Bonn Department of Geography Meckenheimer AIlee 166 D-53115 Bonn Germany

The temperature and soil moisture conditions as well as vegetation patterns were studied to describe the habitat and to model the life cycle of Melanoplusfrigidus, a true alpine grasshopper of the Scandes. In the low alpine belt of the Norwegian Scandes the species colonizes only the warmest microhabitats with maximum soil surface temperatures of 31℃. Vegetation of these habitats consists of shrub-rich heath dominated by Vaccinium myrtillus and Calluna vulgaris. Using continuously measured temperature data, the development times for four different seasons were modeled and related to field observations. The maximum delay of adult molt was estimated to amount to 3 weeks, the delay being determined by the variation in spring temperature conditions between different years. The possibilities of using M. frigidus as an indicator organism of climate change effects on alpine zoo-coenoses of the Scandes are discussed.

关键词： alpine insects climate change indicator life history thermal effective environment

High precision magnetometer for geomagnetic exploration onboard of the China Seismo-Electromagnetic Satellite

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Science China(Technological Sciences) 2018年第5期61卷 659-668页

作者： CHENG BingJun ZHOU Bin MAGNES Werner LAMMEGGER roland POLLINGER Andreas National Space Science Center Chinese Academy of Sciences Space Research Institute Austrian Academy of Sciences Institute of Experimental Physics Graz University of Technology

The China Seismo-Electromagnetic Satellite(CSES) is the first platform of China's earthquake observation system in space and the first satellite of China's geophysical field detection missions. The high precision magnetometer(HPM), which contains two fluxgate sensors and a coupled dark state magnetometer(CDSM), measures the vector of the Earth's magnetic field with a bandwidth from DC to 15 Hz. The two fluxgate sensors are in a gradiometer configuration in order to reduce satellite interferences. Additionally, the CDSM sensor measures the scalar value of the magnetic field with higher accuracy and *** data processing and calibration methods have been prepared to get accurate vector magnetic field data. This includes the calibration of each of the three sensors, the absolute vector correction algorithm, the spacecraft magnetic interference elimination and the coordinate transformation method. Also the instrument performances based on ground calibration activities are shown in this article.

关键词： magnetometer fluxgate magnetometer CPT magnetometer magnetometer calibration data processing

Pancreatic cancer screening in high-risk individuals with genetic susceptibility

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Hepatobiliary Surgery and Nutrition 2023年第4期12卷 590-592页

作者： roland Andersson Daniel Ansari Department of Surgery Clinical Sciences LundLund University and Skåne University HospitalLundSweden

Pancreatic cancer is still associated with a dismal prognosis,sometimes with a 5-year survival reported up to 10%,but the true figure is probably about 5%(1).Major breakthroughs in outcomes are *** avenue for improving is survival is by earlier tumor detection,thereby increasing the proportion of patients that can undergo curative-intent surgery and concomitant *** recent years,optimistic outcomes have been reported for localized-stage disease,with 5-year survival rates of up to 44%(2).

关键词： Screening pancreatic cancer genetic

Application of wave equation theory to improve dynamic cone penetration test for shallow soil characterisation

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Journal of Rock Mechanics and Geotechnical Engineering 2022年第1期14卷 289-302页

作者： Miguel Angel Benz Navarrete Pierre Breul roland Gourvès Sol Solution Géotechnique Réseaux ZA des Portes de Riom Nord23 Avenue Georges GershwinRiom Cedex63204France UniversitéClermont Auvergne Institut PascalUMR CNRS 6602Clermont-Ferrand63000France Polytech Clermont-Ferrand Campus des Cézeaux 2 Avenue Blaise PascalAubière Cedex63178France

Among the geotechnical in situ tests,the dynamic penetration test(DPT)is commonly used around the ***,DPT remains a rough technique and provides only one failure parameter:blow count or cone *** paper presents an improvement of the dynamic cone penetration test(DCPT)for soil characterisation based on the wave equation *** on an instrumented lightweight dynamic penetrometer driving with variable energy,the main process of the test involves the separation and reconstruction of the waves propagating in the rods after each blow and provides a dynamic cone load-penetration(DCLT)*** analytical methodology is used to analyse this curve and to estimate additional strength and deformation parameters of the soil:dynamic and pseudo-static cone resistances,deformation modulus and wave *** carried out in the laboratory on different specimens(wood,concrete,sand and clay)in an experimental sand pit and in the field demonstrated that the resulting DCLT curve is reproducible,sensitive and reliable to the test conditions(rod length,driving energy,etc.)as well as to the soil properties(nature,density,etc.).Obtained results also showed that the method based on shock polar analysis makes it possible to evaluate mechanical impedance and wave velocity of soils,as demonstrated by the comparisons with cone penetration test(CPT)and shear wave velocity measurements made in the *** technique improves the method and interpretation of DPT and provides reliable data for shallow foundation design.

关键词： In situ test Dynamic cone penetrometer P.A.N.D.A. Wave equation Wave decoupling Dynamic cone load-penetration(DCLT)curve

A DLM/FD/IB Method for Simulating Compound Cell Interacting with Red Blood Cells in a Microchannel

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Chinese Annals of Mathematics,Series B 2018年第3期39卷 535-552页

作者： Shihai ZHAO Yao YU Tsorng-Whay PAN roland GLOWINSKI Department of Mathematics Dongbei University of Finance and EconomicsDalian 116023LiaoningChina CGG HoustonTX 77072USA Department of Mathematics University of HoustonHoustonTX 77204USA Department of Mathematics Hong Kong Baptist UniversityHong KongChina

In this article, a computational model and related methodologies have been tested for simulating the motion of a malaria infected red blood cell （iRBC for short） in Poiseuille flow at low Reynolds numbers. Besides the deformability of the red blood cell membrane, the migration of a neutrally buoyant particle （used to model the malaria parasite inside the membrane） is another factor to determine the iRBC motion. Typically an iRBC oscillates in a Poiseuille flow due to the competition between these two factors. The interaction of an iRBC and several RBCs in a narrow channel shows that, at lower flow speed, the iRBC can be easily pushed toward the wall and stay there to block the channel. But, at higher flow speed, RBCs and iRBC stay in the central region of the channel since their migrations axe dominated by the motion of the RBC membrane.

关键词： Compound cell Red blood cells Elastic spring model Fictitious domainmethod Immersed boundary method Microchannel

F?(H2O)+CH3I Ligand Exchange Reaction Dynamics

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Chinese Journal of Chemical Physics 2020年第2期33卷 210-216,I0003,I0039-I0040页

作者： Bjorn Bastian Tim Michaelsen Milan Oncák Jennifer Meyer roland Wester Institut für Ionenphysik und Angewandte Physik Universitat InnsbruckTechnikerstraβe 256020 InnsbruckAustria

Single hydration of the gas phase F^-+CH3I→CH3F reaction allows to probe solvent effects on a fundamental nucleophilic substitution *** the same time,the addition of a solvent molecule opens alternative product ***,we present crossed beam imaging results on the dynamics of the F^-(H2O)+CH3I→[FCH3I]^-+H2O ligand exchange pathway at collision energies between 0.3 and 2.6 *** kinetic energies are constrained by the stability requirement of the weakly bound product *** implies substantial internal excitation of the water molecule and disfavors effcient energy redistribution in an intermediate complex,which is reflected by the suppression of low kinetic energies as collision energy *** 0.3 eV,internal nucleophilic displacement is important and is discussed in light of the competing nucleophilic substitution pathways that form I^- and I^-(H2O).

关键词： Reaction dynamics Ligand exchange Microsolvation Crossed beams Velocity map imaging

Molecular Detection of Pathogens Involved in Sexually Transmitted Infections in Brazzaville, Congo

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Open Journal of Medical Microbiology 2024年第3期14卷 190-205页

作者： Jeanine Mireille Sita Maboundou Bitsi Nina Esther Ngoyi Ontsira Edith Sophie Kombo Bayonne Tanguy Mieret Geril Sekangue Obili Herlen Tsoumou Lina Foungou Kessengue Samantha Potokoue Mpia Chloé Dupont Guilhem Conquet Gickel Mpika Bitsene Bienvenu roland Ibara Ossibi Axel Aloumba Etienne Nguimbi Sylvain Godreuil Faculty of Sciences and Technology Marien NGOUABI University Brazzaville Republic of the Congo Faculty of Health Sciences Marien NGOUABI University Brazzaville Republic of the Congo Bacteriology-Virology Laboratory University Hospital Center Brazzaville Republic of the Congo Department of Infectious Diseases Referral Hospital Center of Talanga Brazzaville Republic of the Congo Parasitology-Mycology Laboratory University Hospital Center Brazzaville Republic of the Congo Department of Gynecology-Obstetrics University Hospital Center Brazzaville Republic of the Congo UMR IRD224-CNRS5290-UM MIVEGEC Infectious Diseases and Vectors: Ecology Genetics Evolution and Control CREES (Reshearch Center in Ecology and Evolution Health) Montpellier France Bacteriology Laboratory Arnaud de Villeneuve University Hospital CHU of Montpellier Montpellier France Department of Infectious Diseases University Hospital Center Brazzaville Republic of the Congo

The objective of this multicentric study was to assess the prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma génitalium and Trichomonas vaginalis infections in Brazzaville, in the Republic of Congo, using molecular methods. From January to December 2021, the sexually transmitted disease risk participants were recruited from six centers: The Association of Young HIV-Positive People of Congo, The Congolese Association for Family Welfare, The Association for Support to Vulnerable Groups, Talangaï hospital, Brazzaville university hospital (outpatient service) and the private clinic COGEMO (outpatient service). The real-time multiplex PCR was carried out to detect these pathogens. Each patient had at least one specimen (urine, urethral, anal and/or vaginal samples). The patients were considered infected when one of their samples was positive. 287 participants made of 227 women and 60 men were tested. The general prevalence of these infections was: Chlamydia trachomatis 2.79%, Neisseria gonorrhoeae 3.14%, Mycoplasma génitalium 3.45% and Trichomonas vaginalis 2.97. The prevalence rates according to sex were: C. trachomatis, M. génitalium, N. gonorrhea and T. vaginalis were 1.32%, 2.05%, 1.32% and 3.42% in women and 8.33%, 7.02%, 10% and 1.75% in men, respectively. Most infected patients were asymptomatic. Prevalence rates were higher in bisexual individuals, with the exception of T. vaginalis which showed higher prevalence in heterosexual patients. The bisexual and homosexual individuals represent a major public health problem in sexually active young adults, particularly among men having sex with men. These sexually transmitted infections are mainly asymptomatic, their diagnosis and management remain difficult in developing countries.

关键词： Prevalence Chlamydia trachomatis Neisseria gonorrhoeae Mycoplasma génitalium Trichomonas vaginalis

Does gemcitabine-based combination therapy improve the prognosis of unresectable pancreatic cancer?

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World Journal of Gastroenterology 2012年第35期18卷 4944-4958页

作者： Chen Sun Daniel Ansari roland Andersson De-Quan Wu Department of Surgery Second Af-filiated Hospital of Harbin Medical University Harbin 150086Heilongjiang Province China Department ofSurgery Clinical Sciences Lund Lund University Sk~ne Univer-sity Hospital SE-22185 Lurid Sweden

AIM:To assess whether gemcitabine-based combination therapy improves the prognosis of unresectable pancreatic cancer compared with gemcitabine treatment ***:A quantitative up-to-date meta-analysis was undertaken to investigate the efficacy of gemcitabine-based combination treatment compared with gemcitabine monotherapy in locally advanced or metastatic pancreatic *** was limited to highquality randomized clinical ***:Twenty-six studies were included in the present analysis,with a total of 8808 patients *** studies were divided into four subgroups based on the different kinds of cytotoxic agents,including platinum,fluoropyrimidine,camptothecin and targeted *** treated with gemcitabine monotherapy had significantly lower objective response rate [risk ratio(RR),0.72;95% confidence interval(CI):0.63-0.83;P < 0.001],and lower 1-year overall survival(RR,0.90;95%CI:0.82-0.99;P = 0.04).Gemcitabine monotherapy caused fewer complications,including fewer grade 3-4 toxicities:including vomiting(RR,0.75;95%CI:0.62-0.89;P = 0.001),diarrhea(RR,0.66;95%CI:0.49-0.89;P = 0.006),neutropenia(RR,0.88;95%CI:0.72-1.06;P = 0.18),anemia(RR,0.96;95%CI:0.82-1.12;P = 0.60),and thrombocytopenia(RR,0.76;95%CI:0.60-0.97;P = 0.03) compared with gemcitabine combination ***:Gemcitabine combination therapy provides a modest improvement of survival,but is associated with more toxicity compared with gemcitabine monotherapy.

关键词： Pancreatic cancer Gemcitabine Combina-tion therapy Outcome Meta-analysis

The Austrian Botanic Gardens Work Group,an Example of Active Networking to Promote Small Botanic Gardens

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植物分类与资源学报 2011年第1期33卷 75-79页

作者： roland K.EBERWEIN Regional Museum of Carinthia Carinthian Botanic CenterKlagenfurt/Woerthersee

The continuously increasing demands on botanic gardens during the last few decades have led to a huge in increase administration and an urgent need for additional specialized personnel,especially botanists,teachers,database specialists and administrative *** of meeting these requirements,many botanic gardens are faceing a severe decrease in funding and *** gardens provide the opportunity to distribute several tasks to different employees,whereas small gardens are short staffed and often run by a single curator who has to fulfill all *** order to meet actual demands more easily,the Austrian botanic gardens are linked nationally via an active *** network not only allows the distribution of information but also facilitates the sharing of duties.A listserver speeds up the communication and correspondence within the workgroup,collection priorities and projects(e.g.,GSPC) are coordinated,seedbanking becomes decentralized,printed matters are shared and distributed,*** gardens with only few employees can participate in projects by taking on small-ideally using with their special resources-in order not to fall *** addition,there is also an urgent need for international networking by means of plant and seed exchange(Index Seminum),BGCI membership,discussion groups,personal contacts and *** statements,special marketing strategies for public relations,integrating projects of other workgroup members and adapted public awareness programs are important to focus attention to small gardens and to help them keep alive.

关键词： Active networking Small botanic gardens Implementing of standards Task sharing Mission statement

Process Design for Hybrid Sheet Metal Components

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Acta Metallurgica Sinica(English Letters) 2015年第12期28卷 1518-1524页

作者： Rico Haase roland Müller Dirk Landgrebe Peter Scholz Matthias Riemer Fraunhofer Institute for Machine Tools and Forming Technology IWU

The global trends towards improving fuel efficiency and reducing CO;emissions are the key drivers for lightweight solutions. In sheet metal processing, this can be achieved by the use of materials with a supreme strength-toweight and stiffness-to-weight ratio. Besides monolithic materials such as high-strength or light metals, in particular metal–plastic composite sheets are able to provide outstanding mechanical properties. Thus, the adaption of conventional, wellestablished forming methods for the processing of hybrid sheet metals is a current challenge for the sheet metal working industry. In this work, the planning phase for a conventional sheet metal forming process is studied aiming at the forming of metal–plastic composite sheets. The single process steps like material characterization, FE analysis, tool design and development of robust process parameters are studied in detail and adapted to the specific properties of metal–plastic composites. In material characterization, the model of the hybrid laminate needs to represent not only the mechanical properties of the individual combined materials, but also needs to reflect the behaviour of the interface zone between *** on experience, there is a strong dependency on temperature as well as strain rate. While monolithic materials show a moderate anisotropic behaviour, loads on laminates in different directions generate different strain states and completely different failure modes. During the FE analysis, thermo-mechanic and thermo-dynamic effects influence the temperature distribution within tool and work pieces and subsequently the forming behaviour. During try out and production phase,those additional influencing factors are limiting the process window even more and therefore need to be considered for the design of a robust forming process. A roadmap for sheet metal forming adjusted to metal–plastic composites is presented in this paper.

关键词： Characterization Hybrids Interface Layered structures Processing Sheet forming