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Pediatric Investigation 2024年第2期8卷 135-138页

作者： samantha Gilg sebastian Acosta rohit s.loomba Claire Rizk Gary E.stapleton David Faraoni Fabio savorgnan Department of Pediatrics Divisions of Critical Care Medicine and CardiologyTexas Children’s Hospital and Baylor College of MedicineHoustonTexasUSA Department of Pediatrics Division of CardiologyTexas Children’s Hospital and Baylor College of MedicineHoustonTexasUSA Department of Pediatrics The Heart InstituteAdvocate Children’s HospitalChicago Medical School and Rosalind Franklin University of Medicine and ScienceOak LawnIllinoisUSA Department of Anesthesiology Arthur S.Keats Division of Pediatric Cardiovascular AnesthesiaPerioperative and Pain MedicineTexas Children’s HospitalBaylor College of MedicineHoustonTexasUSA

The standard of care in the management of d-transposition of the great arteries(TGA)includes the arterial switch operation(AsO).1,2 Although some institutions have begun to publish the results of performing the AsO within the first few hours of life,most centers continue to"electively"delay AsO for several days to allow for a reduction in pulmonary vascular resistance and the stabilization of renal and liver function.1,2 The early initiation of prostaglandin E1(PGE)infusion to maintain ductal patency is a nearly universal component of therapy in order to maintain adequate arterial oxygen saturation and systemic oxygen delivery during the pre-operative period via intercirculatory mixing at the atrial septal and patent ductus arteriosus levels1,3.

关键词： balloon maintain stabilization

study of plasma parameters of coaxial plasma source using triple Langmuir probe and Faraday cup diagnostics

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Plasma science and Technology 2024年第4期26卷 94-100页

作者： sunil KANCHI rohit sHUKLA Archana sHARMA Pulsed Power and Electromagnetics Division Bhabha Atomic Research CentreVisakhapatnam 531011India Homi Bhabha National Institute Mumbai 400085India Beam Technology Development Group Bhabha Atomic Research CentreMumbai 400085India

Coaxial plasma guns are a type of plasma source that produces plasma which propagates radially and axially controlled by the shape of the ground electrode, which has attracted much interest in several applications. In this work, a 120° opening angle of CPG nozzle is used as a plasma gun configuration that operates at the energy of 150 J. The ionization of polyethylene insulator between the electrodes of the gun produces a cloud of hydrogen and carbon *** triple Langmuir probe and Faraday cup are used to measure plasma density and plasma temperature. These methods are used to measure the on-axis and off-axis plasma divergence of the coaxial plasma gun. The peak values of ion densities measured at a distance of 25 mm on-axis from the plasma gun are(1.6±0.5)×10^(19)m^(-3)and(2.8±0.6)×10^(19)m^(-3)for hydrogen and carbon plasma respectively and the peak temperature is 3.02±0.5 eV. The mean propagation velocity of plasma is calculated using the transit times of plasma at different distances from the plasma gun and is found to be 4.54±0.25 cm/μs and 1.81±0.18 cm/μs for hydrogen and carbon plasma respectively. The Debye radius is obtained from the measured experimental data that satisfies the thin sheath approximation. The shot-to-shot stability of plasma parameters facilitates the use of plasma guns in laboratory experiments. These types of plasma sources can be used in many applications like plasma opening switches, plasma devices, and as plasma sources.

关键词： coaxial plasma source triple Langmuir probe Faraday cup plasma density plasma temperature

Progress in metal oxide-based electrocatalysts for sustainable water splitting

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Materials Reports(Energy) 2024年第3期4卷 19-34页

作者： Aasiya s.Jamadar rohit sutar susmita Patil Reshma Khandekar Jyotiprakash B.Yadav Vacuum Techniques and Thin Film Laboratory USICShivaji UniversityKolhapur416004MaharashtraIndia

Metal oxide-based electrocatalysts are promising alternatives to platinum group metals for water splitting due to their low cost,abundant raw materials,and impressive *** review covers recent progress in various metal oxides tailored for hydrogen and oxygen evolution reactions,discussing their crystal structure,composition,and surface modification influence on *** like surface engineering,doping,and nanostructuring are evaluated for enhancing catalytic activity and *** key considerations for commercialization are highlighted,emphasizing ongoing research,innovation,and future scope to drive widespread adoption of water-splitting technology for a cleaner and sustainable future.

关键词： Metal oxide HER OER Electrocatalyst Overall water spilling

Influence of BPPV and Meniere's Disease on Cognitive Abilities: A Questionnaire-Based study

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Journal of Otology 2024年第1期19卷 10-18页

作者： rohit Bhattacharyya Animesh Barman Freddy Antony All India Institute of speech and Hearing MysoreMysuruIndia

The vestibular system connects the inner ear to the midbrain and subcortical structures and can affect cognition. Patients with vertigo often experience cognitive symptoms such as attention deficits, memory problems, and spatial perception difficulties. This study aimed to explore the cognitive impairments associated with Benign paroxysmal positional vertigo(BPPV) and Meniere's Disease(MD). A non-experimental group comparison design was used with 107 participants divided into three groups: Group I(clinically normal), Group II(BPPV), and Group III(MD). Participants completed a questionnaire with 10 cognition-related questions, and their responses were scored. The data were found to be non-normally distributed. The analysis revealed a significant difference in scores between Group I and both Group II and Group III. Chi-square tests showed that the responses to cognition-related questions varied among the groups, with Group II exhibiting more cognitive problems. Associated conditions like hypertension, diabetes, and hearing loss did not significantly influence the responses within each group. This study suggests a significant relationship between cognitive problems and patients with BPPV and MD. However, there was no association found between the cognitive problems experienced in BPPV and MD patients. These findings align with previous research indicating that vestibular disorders can lead to deficits in spatial memory, attention, and other cognitive functions. By understanding the link between cognition and vestibular disorders, we can improve diagnosis and rehabilitation services to enhance the quality of life for these patients.

关键词： BPPV Meniere's disease Cognition Questionnaire

Metal to insulator transition for conducting polymers in plasmonic nanogaps

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Light(science & Applications) 2024年第1期13卷 23-32页

作者： Yuling Xiong rohit Chikkaraddy Charlie Readman shu Hu Kunli Xiong Jialong Peng Qianqi Lin Jeremy J.Baumberg NanoPhotonics Centre Cavendish LaboratoryDepartment of PhysicsUniversity of CambridgeCambridgeCB30HEUK school of Physics&Astronomy University of BirminghamEdgbastonBirminghamUK College of Advanced Interdisciplinary studies and Hunan Provincial Key Laboratory of Novel Nano-Optoelectronic Information Materials and Devices National University of Defense TechnologyChangshaChina Hybrid Materials for Opto-Electronics Group Department of Molecules and MaterialsMESA+Institute for NanotechnologyMolecules Center and Center for Brain-Inspired Nano SystemsFaculty of Science and TechnologyUniversity of TwenteEnschedeNetherlands

Conjugated polymers are promising material candidates for many future applications in flexible displays, organic circuits, and sensors. Their performance is strongly affected by their structural conformation including both electrical and optical anisotropy. Particularly for thin layers or close to crucial interfaces, there are few methods to track their organization and functional behaviors. Here we present a platform based on plasmonic nanogaps that can assess the chemical structure and orientation of conjugated polymers down to sub-10 nm thickness using light. We focus on a representative conjugated polymer, poly(3,4-ethylenedioxythiophene) (PEDOT), of varying thickness (2-20 nm) while it undergoes redox in situ. This allows dynamic switching of the plasmonic gap spacer through a metal-insulator transition. Both dark-field (DF) and surface-enhanced Raman scattering (sERs) spectra track the optical anisotropy and orientation of polymer chains close to a metallic interface. Moreover, we demonstrate how this influences both optical and redox switching for nanothick PEDOT devices.

关键词： transition insulator conjugated

Circulating microRNA expression and nonalcoholic fatty liver disease in adolescents with severe obesity

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World Journal of Gastroenterology 2024年第4期30卷 332-345页

作者： Yi-Jie Li Brittney O Baumert Nikos stratakis Jesse A Goodrich Hao-Tian Wu Jing-Xuan He Yin-Qi Zhao Max T Aung Hong-Xu Wang sandrah P Eckel Douglas I Walker Damaskini Valvi Michele A La Merrill Justin R Ryder Thomas H Inge Todd Jenkins stephanie sisley rohit Kohli stavra A Xanthakos Andrea A Baccarelli Rob McConnell David V Conti Lida Chatzi Department of Population and Public Health sciences Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90032United States Barcelona Institute of Global Health Barcelona Institute of Global HealthBarcelona 08036Spain Department of Environmental Health sciences Mailman School of Public HealthColumbia UniversityNew YorkNY 10032United States Gangarosa Department of Environmental Health Rollins School of Public HealthEmory UniversityAtlantaGA 30329United States Department of Environmental Medicine and Public Health Icahn School of Medicine at Mount SinaiNew YorkNY 10029United States Department of Environmental Toxicology University of CaliforniaDavisCA 95616United States Department of surgery Lurie Children’s Hospital of ChicagoChicagoIL 60611United States Northwestern University Feinberg school of Medicine Northwestern UniversityChicagoIL 60611United States Division of Biostatistics and Epidemiology Cincinnati Children's Hospital Medical CenterCincinnatiOH 45229United States Department of Pediatrics University of Cincinnati College of MedicineCincinnatiOH 45229United States Department of Pediatrics Children’s Nutrition Research Center USDA/ARSBaylor College of MedicineHoustonTX 77030United States Department of Gastroenterology Children’s Hospital Los AngelesLos AngelesCA 90027United States Division of Gastroenterology Hepatology and NutritionCincinnati Children's Hospital Medical CenterCincinnatiOH 45229United States

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is one of the most common chronic liver diseases in children and *** ranges in severity from isolated hepatic steatosis to nonalcoholic steatohepatitis(NAsH),wherein hepatocellular inflammation and/or fibrosis coexist with *** microRNA(miRNA)levels have been suggested to be altered in NAFLD,but the extent to which miRNA are related to NAFLD features remains *** analysis tested the hypothesis that plasma miRNAs are significantly associated with histological features of NAFLD in *** To investigate the relationship between plasma miRNA expression and NAFLD features among adolescents with *** This study included 81 adolescents diagnosed with NAFLD and 54 adolescents without NAFLD from the Teen-Longitudinal Assessment of Bariatric surgery ***-operative core liver biopsies were collected from participants and used to characterize histological features of *** samples were collected during surgery for miRNA profiling.A total of 843 plasma miRNAs were profiled using the HTG Edgeseq *** examined associations of plasma miRNAs and NAFLD features using logistic regression after adjusting for age,sex,race,and other key *** Pathways Analysis was used to identify biological functions of miRNAs that were associated with multiple histological features of *** We identified 16 upregulated plasma miRNAs,including miR-193a-5p and miR-193b-5p,and 22 downregulated plasma miRNAs,including miR-1282 and miR-6734-5p,in adolescents with ***,52,16,15,and 9 plasma miRNAs were associated with NAsH,fibrosis,ballooning degeneration,and lobular inflammation,***,16 miRNAs were associated with two or more histological features of *** those miRNAs,miR-411-5p was downregulated in NAsH,ballooning,and fibrosis,while miR-122-5p,miR-1343-5p,miR-193a-5p,miR-193b-5p,and miR-7845-5p were consistently and posi

关键词： MicroRNA Nonalcoholic fatty liver disease Non-alcoholic steatohepatitis Liver fibrosis Lobular inflammation Ballooning degeneration

Machine learning inspired workflow to revise field development plan under uncertainty

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Petroleum Exploration and Development 2023年第6期50卷 1455-1465页

作者： loomba Ashish Kumar BOTECHIA Vinicius Eduardo sCHIOZER Denis José Universidade Estadual de Campinas SP 13084-778Brazil

We present an efficient and risk-informed closed-loop field development (CLFD) workflow for recurrently revising the field development plan (FDP) using the accrued information. To make the process practical, we integrated multiple concepts of machine learning, an intelligent selection process to discard the worst FDP options and a growing set of representative reservoir models. These concepts were combined and used with a cluster-based learning and evolution optimizer to efficiently explore the search space of decision variables. Unlike previous studies, we also added the execution time of the CLFD workflow and worked with more realistic timelines to confirm the utility of a CLFD workflow. To appreciate the importance of data assimilation and new well-logs in a CLFD workflow, we carried out researches at rigorous conditions without a reduction in uncertainty attributes. The proposed CLFD workflow was implemented on a benchmark analogous to a giant field with extensively time-consuming simulation models. The results underscore that an ensemble with as few as 100 scenarios was sufficient to gauge the geological uncertainty, despite working with a giant field with highly heterogeneous characteristics. It is demonstrated that the CLFD workflow can improve the efficiency by over 85% compared to the previously validated workflow. Finally, we present some acute insights and problems related to data assimilation for the practical application of a CLFD workflow.

关键词： field development plan closed-loop field development reservoir model machine learning reservoir uncertainty optimization reservoir simulation efficiency

Duodenal heterotopic pancreatic tissue:a case report and literature review

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Gastroenterology Report 2015年第3期3卷 262-265页

作者： rohit Mehra Aswini K.Pujahari shyam s.Jaiswal Department of surgery Armed Forces Medical CollegeWanowrieIndia

Heterotopic pancreas is an aberration in the developmental profile of the *** entity is rarely symptomatic and its malignant transformation is even ***,when present,it poses a diagnostic dilemma to clinicians,as little help comes from gastroenteroscopy and *** exploration remains the only option at times,and it is the histopathological examination that finally clears the *** case report reveals the elusive nature of malignancy in heterotopic pancreas in the duodenum.

关键词： heterotopic pancreas malignant transformation small bowel obstruction

Nitrogen fractionation of certain conventional-and lesser-known by-products for ruminants

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Animal Nutrition 2017年第2期3卷 186-190页

作者： M.s.Mahesh sudarshan s.Thakur rohit Kumar Tariq A.Malik Rajkumar Gami Animal Nutrition Division ICAR-National Dairy Research Institute (Deemed University) Division of Animal Nutrition Sher-e-Kashmir University of Agricultural Science and Technology-Jammu NDDB-Ration Balancing Program Office

Dietary proteins for ruminants are fractionated according to solubility, degradability and digestibility. In the present experiment, 11 vegetable protein meals and cakes used in ruminant nutrition were included with a main focus on determining various nitrogen(N) fractions in vitro. Total N(N×6.25) content varied from 22.98%(mahua cake) to 65.16%(maize gluten meal), respectively. Guar meal korma contained the lowest and rice gluten meal had the highest acid detergent insoluble nitrogen(ADIN; N×6.25). Boratephosphate insoluble N(BIN, N×6.25) and streptomyces griseus protease insoluble N(PIN; N×6.25) were higher(Ps, whereas groundnut cake and sunflower cake had lower(P spectively. Available N, calculated with the assumption that ADIN is indigestible, was maximum in guar meal korma and minimum in rice gluten meal. Furthermore, rapid and slowly degradable N(N × 6.25) was found to be higher(P spectively. Intestinal digestion of rumen undegradable protein, expressed as percent of PIN, was maximum in guar meal korma and minimum in rice gluten meal. It was concluded that vegetable protein meals differed considerably in N fractions, and therefore, a selective inclusion of particular ingredient is needed to achieve desired level of N fractions to aid precision N rationing for an improved production performance of ruminants.

关键词： ADIN Protein degradability soluble protein streptomyces griseus protease

Modified branch-and-bound algorithm for unravelling optimal PMU placement problem for power grid observability: A comparative analysis

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CAAI Transactions on Intelligence Technology 2021年第4期6卷 450-470页

作者： rohit Babu saurav Raj Bishwajit Dey Biplab Bhattacharyya Department of Electrical and Electronics Enginecring Lendi Institute of Engincering and TechnologyJonnadaAndhra PradeshIndia Department of Electrical Engineering Institute of Chemical Technology-MunbaiMarathwada CampusJalnaMaharashtraIndia Department of lectrical Engineering IndianInstitute of TechnologyDhanbadJharkhandIndia

safe operation of the power grid requires a complete and robust control network to ensure full observability;However,redundancy measurements can create problems in expense,management,and *** optimal phasor measurement unit(PMU)positioning problem(OPPP)is proposed to limit the number of PMUs deployed in the power grid and ensure the whole grid's observability in the meantime.A modified branch-and-bound algorithm(MBBA)to unravel the OPPP is *** BBA,which uses a single search order to create a binary tree,gives only one solution to the OPPR although more than one optimal solution *** proposed MBBA method consists of two different stages:the vertexes in the search tree are investigated by depth-first search(DFs)in stage 1,and the search route continues as the breadth-first *** stage 1,the LP relaxing problems are solved by dual simplex,and in stage 2,the basic viable solution from stage 1 is used to configure the primary simplex until the optimum solution is *** is formulated as a binary decision variable MBBA model,minimizing linear objective function subject to linear matrix observability *** MBBA model is unravelled using a linear integer-based external approximation *** test systems are used to check the feasibility of the proposed *** software performs simulation based on a number of graph theory-based methods such as DFs,graph-theoretical method,simulated annealing,and recursive *** algorithms are compared to the algorithmic perspective of the proposed MBBA *** test network results confirm the validity of the proposed methodology.

关键词： optimal branch observability