检索结果-南通市图书馆

Importance of fatigue and its measurement in chronic liver disease

World Journal of Gastroenterology 2019年第28期25卷 3669-3683页

作者： Lynn H Gerber Ali A Weinstein rohini mehta Zobair M Younossi Department of Medicine Beatty Center for Liver and Obesity Research Inova Health System Falls Church VA 22042 United States Center for the Study of Chronic Illness and Disability George Mason University Fairfax VA 22030 United States Beatty Center for Liver and Obesity Research Inova Health System Falls Church VA 22042 United States

The mechanisms of fatigue in the group of people with non-alcoholic fatty liver disease and non-alcoholic steatohepatitis are protean. The liver is central in the pathogenesis of fatigue because it uniquely regulates much of the storage, release and production of substrate for energy generation. It is exquisitely sensitive to the feedback controlling the uptake and release of these energy generation substrates. Metabolic contributors to fatigue, beginning with the uptake of substrate from the gut, the passage through the portal system to hepatic storage and release of energy to target organs (muscle and brain) are central to understanding fatigue in patients with chronic liver disease. Inflammation either causing or resulting from chronic liver disease contributes to fatigue, although inflammation has not been demonstrated to be causal. It is this unique combination of factors, the nexus of metabolic abnormality and the inflammatory burden of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis that creates pathways to different types of fatigue. Many use the terms central and peripheral fatigue. Central fatigue is characterized by a lack of self-motivation and can manifest both in physical and mental activities. Peripheral fatigue is classically manifested by neuromuscular dysfunction and muscle weakness. Therefore, the distinction is often seen as a difference between intention (central fatigue) versus ability (peripheral fatigue). New approaches to measuring fatigue include the use of objective measures as well as patient reported outcomes. These measures have improved the precision with which we are able to describe fatigue. The measures of fatigue severity and its impact on usual daily routines in this population have also been improved, and they are more generally accepted as reliable and sensitive. Several approaches to evaluating fatigue and developing endpoints for treatment have relied of biosignatures associated with fatigue. These have bee

关键词： Fatigue Chronic liver disease Non-alcoholic fatty liver diseases Nonalcoholic steatohepatitis Measurement Patient-reported outcomes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Quantized autoencoder(QAE)intrusion detection system for anomaly detection in resource-constrained loT devices using RT-loT2022 dataset

引用

Cybersecurity 2024年第2期7卷 13-27页

作者： B S Sharmila rohini Nagapadma Depatment of Electronics and Communication Engineering The National Institute of EngineeringMysoreKarnataka 570008India

In recent years,many researchers focused on unsupervised learning for network anomaly detection in edge devices to identify *** deployment of the unsupervised autoencoder model is computationally expensive in resource-constrained edge *** study proposes quantized autoencoder(QAE)model for intrusion detection systems to detect *** is an optimization model derived from autoencoders that incorporate pruning,clustering,and integer quantization *** autoencoder uint8(QAE-u8)and quantized autoencoder float16(QAE-f16)are two variants of QAE built to deploy computationally expensive Al models into Edge ***,we have generated a Real-Time Internet of Things 2022 dataset for normal and attack *** autoencoder model operates on normal traffic during the training *** same model is then used to reconstruct anomaly traffic under the assumption that the reconstruction error(RE)of the anomaly will be high,which helps to identify the ***,we study the performance of the autoencoders,QAE-u8,and QAE-f16 using accuracy,precision,recall,and F1 score through an extensive experimental *** showed that QAE-u8 outperforms all other models with a reduction of 70.01%in average memory utilization,92.23%in memory size compression,and 27.94%in peak CPU ***,the proposed QAE-u8 model is more suitable for deployment on resource-constrained IoT edge devices.

关键词： IoT constrained system

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of contrasting climates on antioxidant and bioactive constituents in five medicinal herbs in Western Himalayas

引用

Journal of Mountain Science 2016年第3期13卷 484-492页

作者： Tarandeep KAUR rohini BHAT Dhiraj VYAS Biodiversity and Applied Botany Division Indian Institute of Integrative Medicine(CSIR) Academy of Scientific and Innovative Research Indian Institute of Integrative Medicine (CSIR)

To understand the effect of climate change on constitutive antioxidant and biochemical metabolites in Western Himalayas, five medicinal herbs were selected and grown at two altitudes in Jammu(305 m) and Srinagar(1730 m) with subtropical and temperate climates, *** variations were observed in phenols and flavonoids in Hypericum perforatum L., Matricaria chamomilla L., Thymus vulgaris L., Cynara cardunculus L. and Echinacea purpurea L. growing at two locations. High altitude temperate site show variable(up to 13 fold) increase in their ***(1.3- 1.8 times), sugars(2.8- 4.1 times) and free amino acid(1.04- 1.22 times) were also higher at Srinagar(1730 m). Within these plants, *** and M. chamomilla have shown higher accumulation of phenols, xanthophylls and proline even at subtropical environment in Jammu(305 m)suggesting potential for increasing their geographical area. The results demonstrate that changing environmental conditions significantly affect the bioactive constituents, which accumulate as a defence strategy by these temperate plants. Their medicinal significance during climate change scenario has also been discussed.

关键词： Medicinal herbs Flavonoids Phenols Glutathione Western Himalayas Climate change

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Practical realization of dual S arm antenna for beam steering applications

引用

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第12期8卷 1901-1904页

作者： mehta Amit Institute of Advanced Telecommunications University of WalesSwansea SA2 8PP United Kingdom

A dual S shaped micro strip antenna with a realistic feed is proposed for generation of tilted beam radiation pattern pertaining for beam steering applications. To achieve this, four feeding points are located at a distance of 5.6 mm from the antenna centre. These feeding points when excited one by one generate four tilted beams in four different space quadrants, thus yielding a beam steerable antenna, Importantly, since the proposed antenna is symmetrical in the structure, all the four tilted beams have the same radiation pattern characteristics. A further enhancement of the antenna bandwidth is also achieved using 100-μn capacitive coupling between the feed and the antenna strip.

关键词： Beam steerable antenna S antenna. Switched beams

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Mechanical and electronic approaches to improve the sensitivity of microcantilever sensors

引用

Acta Mechanica Sinica 2009年第1期25卷 1-12页

作者： Madhu Santosh Ku Mutyala Deepika Bandhanadham Vijaya rohini Pendyala Institute for Micromanufacturing Louisiana Tech University

Advances in the field of micro electro mechanical systems and their uses now offer unique opportunities in the design of ultrasensitive analytical tools. The analytical community continues to search for cost-effective, reliable, and even portable analytical techniques that can give reliable and fast response results for a variety of chemicals and biomolecules. Microcantilevers （MCLs） have emerged as a unique platform for label-free chem-sensor or bioassay. Several electronic designs, including piezoresistive, piezoelectric, and capacitive approaches, have been applied to measure the bending or frequency change of the MCLs upon exposure to chemicals. This review summarizes mechanical, fabrication, and electronics approaches to increase the sensitivity of MCL sensors.

关键词： Microcantilever Sensor MEMS Sensitivity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An Efficient Image Analysis Framework for the Classification of Glioma Brain Images Using CNN Approach

引用

Computers, Materials & Continua 2020年第6期63卷 1133-1142页

作者： Ravi Samikannu rohini Ravi Sivaram Murugan Bakary Diarra Faculty of Electrical Engineering Botswana International University of Science and TechnologyPalapyeBotswana Faculty of Computer Science Engineering Vivekanandha College of Engineering for WomenNamakkal637205India Department of Computer Networking Lebanese French UniversityErbil44001Iraq Institute of Applied Sciences University of SciencesTechniques and Technologies of BamakoBamakoMali

The identification of brain tumors is multifarious work for the separation of the similar intensity pixels from their surrounding *** detection of tumors is performed with the help of automatic computing technique as presented in the proposed *** non-active cells in brain region are known to be benign and they will never cause the death of the *** non-active cells follow a uniform pattern in brain and have lower density than the surrounding *** Magnetic Resonance(MR)image contrast is improved by the cost map construction *** deep learning algorithm for differentiating the normal brain MRI images from glioma cases is implemented in the proposed *** technique permits to extract the linear features from the brain MR image and glioma tumors are detected based on these extracted *** k-mean clustering algorithm the tumor regions in glioma are *** proposed algorithm provides high sensitivity,specificity and tumor segmentation accuracy.

关键词： Brain glioma features tumors classifications

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Multispectral harvesting rare-earth oxysulphide based highly efficient transparent luminescent solar concentrator

引用

Journal of Rare Earths 2022年第1期40卷 41-48页

作者： Vanjula Kataria Dalip Singh mehta Green Photonics Laboratory Department of PhysicsIndian Institute of Technology(IIT)DelhiHauz KhasDelhi110016India

Transparent luminescent solar concentrator(LSC)is extensively regarded as the most promising sunlight tapping device for its application in buildings integrated with photovoltaics(BIPV)or as solar window *** LSCs doped with organic dyes suffered from high reabsorption losses with no transparency;whereas,recently reported heavy metal-doped quantum dots avoided such losses but possessed the risk of high toxicity and low ambient ***,luminophores with massive spectral shifts and co rdial relationships with the enviro nment are very much *** this paper,we report the fabrication of PMMA based transparent LSC embedded with nanocrystals of environmental friendiness and multispectral harvesting gadolinium oxysulphide(Gd_(2)O_(2) S:Er,Yb)*** Gd_(2)O_(2) S:Er,Yb nanofluorophore absorbs various excitation wavelengths ranging from UV to NIR and emits in the visible region offering huge Stoke’s and anti-Stoke’s shift *** non-existent reabsorption losses and overlapping maxima of Gd_(2)O_(2) S:Er,Yb nanofluorophore generated photon flux with solar cells’responsivity enhance the efficiency characteristics of the LSC *** analysis of LSC as a function of varying nanofluorophore dispersion ratio and changing edge width optimizes the fabrication process and exhibits high power conversion efficiency of-6,93%and optical efficiency of-8.57%.The LSC slab demonstrates high photostability under irradiation for prolonged hours without any dip in the emission *** Gd_(2)O_(2) S:Er,Yb nanofluorophore diffused LSC waveguide offering spectral tunability,cost-reduction,efficiency enhancement,and high concentration factor whilst being sustainable for long term use makes it a fascinating transparent solar window.

关键词： Luminescent solar concentrator Gadolinium oxysulphide Stoke's shift Anti-Stoke's shift Efficiency enhancement Photostability

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Analytical method for cell displacement defect quantum-dot cellular automata primitive

引用

Journal of Electronic Science and Technology 2023年第1期21卷 26-34页

作者： Vaishali Dhare Usha mehta Institute of Technology Nirma UniversityAhmedabad382481India

Quantum-dot cellular automata(QCA)is an emerging computational paradigm which can overcome scaling limitations of the existing complementary metal oxide semiconductor(CMOS)*** existence of defects cannot be ignored,considering the fabrication of QCA devices at the molecular level where it could alter the ***,defects in QCA devices need to be *** far,the simulation-based displacement defect analysis has been presented in the literature,which results in an increased demand in the corresponding mathematical *** this paper,the displacement defect analysis of the QCA main primitive,majority voter(MV),is presented and carried out both in simulation and mathematics,where the kink energy based mathematical model is *** results demonstrate that this model is valid for the displacement defect in QCA MV.

关键词： Displacement defect Kink energy Majority voter(MV) Quantum-dot cellular automata (QCA)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

3D printed microfluidic devices:a review focused on four fundamental manufacturing approaches and implications on the field of healthcare

引用

Bio-Design and Manufacturing 2021年第2期4卷 311-343页

作者： Viraj mehta Subha N.Rath Regenerative Medicine and Stem Cells Laboratory Department of Biomedical EngineeringIndian Institute of Technology HyderabadKandiTelangana 502285India

In the last fewyears,3D printing has emerged as a promising alternative for the fabrication ofmicrofluidic devices,overcoming some of the limitations associated with conventional ***(SLA),extrusion-based technology,and inkjet 3D printing are three of the widely used 3D printing technologies owing to their accessibility and *** devices can be 3D printed by employing a manufacturing approach from four fundamental manufacturing approaches classified as(1)direct printing approach,(2)mold-based approach,(3)modular approach,and(4)hybrid *** evaluate the feasibility of 3D printing technologies for fabricating microfluidic devices,a review focused on 3D printing fundamental manufacturing approaches has been *** a broad spectrum of additive manufacturing materials,3D printed microfluidic devices have been implemented in various fields,including biological,chemical,and material ***,some crucial challenges are associated with the same,including low resolution,low optical transparency,cytotoxicity,high surface roughness,autofluorescence,non-compatibility with conventional sterilization methods,and low gas *** recent research progress in materials related to additive manufacturing has aided in overcoming some of these ***,we outline possible implications of 3D printed microfluidics on the various fields of healthcare such as in vitro disease modeling and organ modeling,novel drug development,personalized treatment for cancer,and cancer drug screening by discussing the current state and future outlook of 3D printed‘organs-on-chips,’and 3D printed‘tumor-on-chips.’We conclude the review by highlighting future research directions in this field.

关键词： 3D printing Additive manufacturing Microfluidics Lab-on-a-chip Organ-on-a-chip Tumor-on-a-chip

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of NO_3^--N Enrichment on Seawater Stress Tolerance of Jerusalem Artichoke (Helianthus tuberosus)

引用

Pedosphere 2008年第1期18卷 113-123页

作者： S.K.mehta College of Resources and Environmental Sciences Nanjing Agricultural University

A hydroponic experiment with six treatments, i.e., 0% seawater （control）, 10% seawater, 25% seawater, 0% seawater ＋ N （7.5 mmol L-1 NaNO3）, 10% seawater ＋ N （7.5 mmol L-1 NaO3）, and 25% seawater ＋ N （7.5 mmol L-1 NaNO3）, was carried out to study the effect of nitrogen addition on the growth and physiological and biochemical characteristics of Jerusalem artichoke （Helianthus tuberosus） seedlings under seawater stress. The 10% seawater stress treatment had the least effect on plant growth while at 25% seawater growth was significantly inhibited. The malondialdehyde content and electrolyte leakage in leaves under 10% seawater were similar to those of the control, but significantly higher under the 25% seawater stress. The activities of superoxide dismutase, peroxidase and catalase in the leaves increased concomitantly with increasing seawater concentration and time. Proline and soluble-sugars in the leaves and Na^＋, K^＋, and Cl- contents in shoots and roots increased significantly with the concentration of seawater increasing. Nitrogen addition resulted in increasing fresh and dry weights of shoots and roots compared with seawater treatment without N. Nitrogen supplementation also significantly enhanced the activities of antioxidant enzymes in leaves. Addition of N to seawater enhanced the contents of proline and soluble-sugars in the leaves and K^＋ and total-N in the aerial parts and roots of H. tuberosus, but it resulted in declined concentrations of Na^＋ and Cl- in the aerial parts and roots. Nitrogen addition ameliorated the toxicity of seawater by improving the antioxidative enzymes, accumulating of proiine and soluble-sugars, and altering the distribution of inorganic ions in H. tuberosus.

关键词： Helianthus tuberosus ions distributions malondialdehyde nitrate seawater stress

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：