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Structural optimization of filament wound composite pipes

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Frontiers of Structural and Civil Engineering 2022年第8期16卷 1056-1069页

作者： roham RAFIEE Reza SHAHZADI Hossein SPERESP Faculty of New Science and Technologies University of TehranTehran ***Iran

An optimization procedure is developed for obtaining optimal structural design of filament wound composite pipes with minimum cost utilized in pressurized water and waste-water ***,the short-term and long-term design constraints dictated by international standards are ***,proper computational tools are developed for predicting the structural properties of the composite pipes based on the design architecture of *** developed computational tools are validated by relying on experimental ***,an integrated design-optimization process is developed to minimize the price as the main objective,taking into account design requirements and manufacturing limitations as the constraints and treating lay-up sequence,fiber volume fraction,winding angle,and the number of total layers as design *** developed method is implemented in various case studies,and the results are presented and discussed.

关键词： composite pipes optimization experimental validation computational modeling filament winding

Theoretical study of failure in composite pressure vessels subjected to low-velocity impact and internal pressure

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Frontiers of Structural and Civil Engineering 2020年第6期14卷 1349-1358页

作者： roham RAFIEE Hossein RASHEDI Shiva REZAEE Composites Research Laboratory Faculty o f New Science&TechnologiesUniversity o f TehranTehran ***Iran

A theoretical solution is aimed to be developed in this research for predicting the failure in internally pressurized composite pressure vessels exposed to low-velocity *** in-plane and out-of-plane failure modes are taken into account simultaneously and thus all components of the stress and strain fields are *** this purpose,layer-wise theory is employed in a composite cylinder under internal pressure and low-velocity *** stress/strain components are fed into appropriate failure criteria for investigating the occurrence of *** case of experiencing any in-plane failure mode,the evolution of damage is modeled using progressive damage modeling in the context of continuum damage ***,mechanical properties of failed ply are degraded and stress analysis is performed on the updated status of the *** the event of delamination occurrence,the solution is *** obtained results are validated with available experimental observations in open *** is observed that the sequence of in-plane failure and delamination varies by increasing the impact energy.

关键词： composite pressure vessel low-velocity impact failure theoretical solution progressive damage modeling

Investigating the influence of delamination on the stiffness of composite pipes under compressive transverse loading using cohesive zone method

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Frontiers of Structural and Civil Engineering 2019年第6期13卷 1316-1323页

作者： Sattar MALEKI roham RAFIEE Abolfazl HASANNIA Mohammad Reza HABIBAGAHI Department of Mechanical Engineering Faculty of EngineeringQuchan University of TechnologyQuchan 94771-67335Iran Composites Research Laboratory Faculty of New Sciences and TechnologiesUniversity of TehranTehran ***Iran

The effect of delamination on the stiffness reduction of composite pipes is studied in this *** stiffness test of filament wound composite pipes is simulated using cohesive zone *** modeling is accomplished to study the effect of the geometrical parameters including delamination size and its position with respect to loading direction on stiffness of the composite *** first,finite element results for stiffness test of a perfect pipe without delamination are validated with the experimental results according to ASTM *** is seen that the finite element results agree well with experimental *** the finite element model is developed for composite pips with delaminated areas with different primary ***,the effect of the size of delaminated region on longitudinal and tangential directions and also its orientation with respect to loading direction on delamination propagation and stiffness reduction of the pipes is assessed.

关键词： delamination composite pipes stiffness test cohesive zone method

Optimization of the mechanical performance and damage failure characteristics of laminated composites based on fiber orientation

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Frontiers of Structural and Civil Engineering 2023年第9期17卷 1357-1369页

作者： Hussein DALFI Anwer AL-OBAIDI Abdalameer TARIQ Hussein RAZZAQ roham RAFIEE Mechanical Department College of EngineeringUniversity of WasitKut 35140Iraq Composites Research Laboratory Faculty of New Sciences and TechnologiesUniversity of TehranTehran 33134Iran

In this study,the effect of fiber angle on the tensile load-bearing performance and damage failure characteristics of glass composite laminates was investigated experimentally,analytically,and *** glass fabric in the laminate was perfectly aligned along the load direction(i.e.,at 0°),offset at angles of 30°and 45°,or mixed in different directions(i.e.,0°/30°or 0°/45°).The composite laminates were fabricated using vacuum-assisted resin *** influence of fiber orientation angle on the mechanical properties and stiffness degradation of the laminates was studied via cyclic tensile strength ***,simulations have been conducted using finite element analysis and analytical approaches to evaluate the influence of fiber orientation on the mechanical performance of glass *** testing revealed that,although the composite laminates laid along the 0°direction exhibited the highest stiffness and strength,their structural performance deteriorated *** also determined that increasing the fiber offset angle(i.e.,30°)could optimize the mechanical properties and damage failure characteristics of glass *** results of the numerical and analytical approaches demonstrated their ability to capture the mechanical behavior and damage failure modes of composite laminates with different fiber orientations,which may be used to prevent the catastrophic failures that occur in composite laminates.

关键词： fiber orientation composite laminates stiffness degradation analytical approaches finite element analysis

Human islet amyloid polypeptide:A therapeutic target for the management of type 2 diabetes mellitus

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Journal of Pharmaceutical Analysis 2022年第4期12卷 556-569页

作者： Pratiksha H.roham Shreyada N.Save Shilpy Sharma Department of Biotechnology Savitribai Phule Pune UniversityGaneshkhind41100India

Type 2 diabetes mellitus(T2DM)and other metabolic disorders are often silent and go unnoticed in patients because of the lack of suitable prognostic and diagnostic *** current therapeutic regimens available for managing T2DM do not reverse diabetes;instead,they delay the progression of *** efficacy(in principle)may be significantly improved if implemented at earlier *** misfolding and aggregation of human islet amyloid polypeptide(hIAPP)or amylin has been associated with a gradual decrease in pancreatic b-cell function and mass in patients with ***,hIAPP has been recognized as a therapeutic target for managing *** review summarizes hIAPP's role in mediating dysfunction and apoptosis in pancreatic b-cells via induction of endoplasmic reticulum stress,oxidative stress,mitochondrial dysfunction,inflammatory cytokine secretion,autophagy blockade,***,it explores the possibility of using intermediates of the hIAPP aggregation pathway as potential drug targets for T2DM ***,the effects of common antidiabetic molecules and repurposed drugs;other hIAPP mimetics and peptides;small organic molecules and natural compounds;nanoparticles,nanobodies,and quantum dots;metals and metal complexes;and chaperones that have demonstrated potential to inhibit and/or reverse hIAPP aggregation and can,therefore,be further developed for managing T2DM have been discussed.

关键词： Aggregation Inhibitor Therapeutic target hIAPP Type 2 diabetes mellitus

Nat Immunol:科学家阐明如何有效抑制自身免疫疾病的发生

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现代生物医学进展 2017年第8期17卷 I0002-I0003页

作者： Thomas H auml ggl #x000F6 f, Saikiran K Sedimbi Mikael C I Karlsson Jennifer L Yates Elizabeth A Leadbetter roham Parsa Robert A Harris Briana Hauff Salas Elizabeth A Leadbetter Department of Microbiology Tumor and Cell Biology Karolinska Institutet Solna Sweden. Trudeau Institute Saranac Lake New York USA. Department of Clinical Neuroscience Karolinska Institutet Centre for Molecular Medicine Karolinska University Hospital at Solna Solna Sweden. Department of Microbiology Immunology and Molecular Genetics University of Texas Health Science Center at San Antonio San Antonio Texas USA.

机体免疫系统中一种未知的安全机制能够保持机体免于自身免疫疾病，日前一项刊登于国际杂志Nature Immunology上的研究报告中，来自瑞典卡罗琳学院的研究人员通过研究发现。机体先天性免疫系统中的细胞能够阻止后天性的免疫系统对机体... 详细信息

机体免疫系统中一种未知的安全机制能够保持机体免于自身免疫疾病，日前一项刊登于国际杂志Nature Immunology上的研究报告中，来自瑞典卡罗琳学院的研究人员通过研究发现。机体先天性免疫系统中的细胞能够阻止后天性的免疫系统对机体固有的细胞产生反应，否则就会引发诸如系统性红斑狼疮等自身免疫疾病的发生。

关键词：自身免疫疾病机体免疫系统 Nat 科学家系统性红斑狼疮安全机制研究人员后天性

Comparison of chest CT scan findings between COVID-19 and pulmonary contusion in trauma patients based on RSNA criteria:Established novel criteria for trauma victims

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Chinese Journal of Traumatology 2022年第3期25卷 170-176页

作者： Hossein Abdolrahimzadeh Fard Salahaddin Mahmudi-Azer Qusay Abdulzahraa Yaqoob Golnar Sabetian Pooya Iranpour Zahra Shayan Shahram Bolandparvaz Hamid Reza Abbasi Shiva Aminnia Maryam Salimi Mohammad Mehdi Mahmoudi Shahram Paydara roham Borazjani Ali Taheri Akerdi Masome Zare Leila Shayan Mohammadreza Sasani Trauma Research Center Shahid Rajaee(Emtiaz)Trauma HospitalShiraz University of Medical SciencesShirazIran Department of General Surgery Kufa University of Medical SciencesNajafIraq Department of Intensive Care Medicine Trauma Research CenterShahid Rajaee(Emtiaz)HospitalShiraz University of Medical SciencesShirazIran Department of Radiology Medical Imaging Research Center.School of MedicineShiraz University of Medical SciencesShirazIran Department of Biostatistics Trauma Research CenterSchool of MedicineShiraz University of Medical SciencesShirazIran Student Research Committee Shiraz University of Medical SciencesShirazIran Trauma Intensive Care Unit Trauma Research CenterShahid Rajaee(Emtiaz)Trauma HospitalShiraz University of Medical SciencesShirazIran

Propose:In this study,we re-assessed the criteria defined by the radiological society of North America(RSNA)to determine novel radiological findings helping the physicians differentiating COVID-19 from pulmonary ***:All trauma patients with blunt chest wall trauma and subsequent pulmonary contusion,COVID-19-related signs and symptoms before the trauma were enrolled in this retrospective study from February to May *** patients(Group P)were then classified into two groups based on polymerase chain reaction tests(Group Pa for positive patients and Pb for negative ones).Moreover,44 patients from the prepandemic period(Group PP)were *** were matched to Group P regarding age,sex,and trauma-related *** radiologists blindly reviewed the CT images of all enrolled patients according to criteria defined by the RSNA *** radiological findings were compared between Group P and Group PP;statistically significant ones were re-evaluated between Group Pa and Group Pb ***,the sensitivity and specificity of each significant findings were *** Chi-square test was used to compare the radiologica丨findings between Group P and Group ***:In the Group PP,73.7%of all ground-glass opacities(GGOs)and 80%of all multiple bilateral GGOs were detected(p<0.001 and p=0.25,respectively).Single bilateral GGOs were only seen among the Group *** Chi-square tests showed that the prevalence of diffused GGOs,multiple unilateral GGOs,multiple consolidations,and multiple bilateral consolidations were significantly higher in the Group P(p=0.001,0.01,0.003,and 0.003,respectively).However,GGOs with irregular borders and single consolidations were more significant among the Group PP(p=0.01 and 0.003,respectively).Of note,reticular distortions and subpleural spares were exclusively detected in the Group ***:We concluded that the criteria set by RSNA for the diagnosis of COVID-19 are not appropriate in trauma ***

关键词： Chest wall CT Contusion COVID-19 RSNA criteria Trauma