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How completely are randomized controlled trials of non-pharmacological interventions following concussion reported? A systematic review

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Journal of Sport and Health Science 2024年第4期13卷 537-547页

作者： Jacqueline Josee van Ierssel Olivia Galea Kirsten Holte Caroline Luszawski Elizabeth Jenkins Jennifer O’Neil Carolyn A Emery Rebekah Mannix Kathryn Schneider Keith owen Yeates roger Zemek Children’s Hospital of Eastern Ontario Research Institute OttawaON K1H 8L1Canada The Centre for Health Activity and Rehabilitation ResearchUniversity of OtagoDunedin 9016New Zealand Sport Injury Prevention Research Centre Faculty of KinesiologyUniversity of CalgaryCalgaryAB T2N 1N4Canada Alberta Children’s Hospital Research Institute University of Calgary CalgaryAB T2N 1N4Canada Hotchkiss Brain Institute University of CalgaryCalgaryAB T2N 4N1Canada Department of Psychology University of CalgaryCalgaryAB T2N 1N4Canada g Faculty of MedicineUniversity of OttawaOttawaON K1H 8M5Canada School of Rehabilitation Sciences University of OttawaOttawaON K1H 8M5Canada Bruyere Research Institute OttawaON K1N 5C8Canada Departments of Pediatrics and Emergency Medicine Harvard Medical SchoolBostonMA 02115USA Departments of Pediatrics and Emergency Medicine University of OttawaOttawaON K1H 8M5Canada

Purpose:The study aimed to examine the reporting completeness of randomized controlled trials(RCTs)of non-pharmacological interventions following ***:We searched MEDLINE,Embase,PsycInfo,CINAHL,and Web of Science up to May *** reviewers independently screened studies and assessed reporting completeness using the Template for Intervention Description and Replication(TIDieR),Consensus on Exercise Reporting Template(CERT),and international Consensus on Therapeutic Exercise aNd Training(i-CONTENT)*** information was sought my study authors where reporting was *** of bias(ROB)was assessed with the Cochrane ROB-2 *** examining non-pharmacological interventions following ***:We included 89 RCTs(n=53 high ROB)examining 11 different interventions for concussion:sub-symptom threshold aerobic exercise,cervicovestibular therapy,physical/cognitive rest,vision therapy,education,psychotherapy,hyperbaric oxygen therapy,transcranial magnetic stimulation,blue light therapy,osteopathic manipulation,and head/neck *** scores were:TIDieR 9/12(75%;interquartile range(IQR)=5;range:5-12),CERT 17/19(89%;IQR=2;range:10-19),and i-CONTENT 6/7(86%;IQR=1;range:5-7).Percentage of studies completely reporting all items was TIDieR 35%(31/89),CERT 24%(5/21),and i-CONTENT 10%(2/21).Studies were more completely reported after publication of TIDieR(t_(87)=2.08;p=0.04)and CERT(t_(19)=2.72;p=0.01).Reporting completeness was not strongly associated with journal impact factor(TIDieR:rs=0.27;p=0.01;CERT:r_(s)=-0.44;p=0.06;i-CONTENT:r_(s)=-0.17;p=0.48)or ROB(TIDieR:rs=0.11;p=0.31;CERT:rs=0.04;p=0.86;i-CONTENT:rs=0.12;p=0.60).Conclusion:RCTs of non-pharmacological interventions following concussion demonstrate moderate to good reporting completeness,but are often missing key components,particularly modifications,motivational strategies,and qualified *** completeness improved after TIDieR and CERT publication,but p

关键词： Concussion Intervention Randomized controlled trial Systematic review

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Spatiotemporal dynamics in butterfly hybrid zones

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Insect Science 2024年第2期31卷 328-353页

作者： Ananda R.Pereira Martins Natalie B.Warren W.owen McMillan Rowan D.H.Barrett Redpath Museum McGill University859 Sherbrooke Street WestMontrealQuebecCanada Smithsonian Tropical ResearchInstitute GamboaPanama CityPanama

Evaluating whether hybrid zones are stable or mobile can provide novelinsights for evolution and conservation biology. Butterflies exhibit high sensitivity to envi-ronmental changes and represent an important model system for the study of hybrid zoneorigins and maintenance. Here, we review the literature exploring butterfly hybrid zones,with a special focus on their spatiotemporal dynamics and the potential mechanisms thatcould lead to their movement or stability. We then compare different lines of evidenceused to investigate hybrid zone dynamics and discuss the strengths and weaknesses ofeach approach. Our goal with this review is to reveal general conditions associated withthe stability or mobility of butterfly hybrid zones by synthesizing evidence obtained us-ing different types of data sampled across multiple regions and spatial scales. Finally, wediscuss spatiotemporal dynamics in the context of a speciation/divergence continuum, therelevance of hybrid zones for conservation biology, and recommend key topics for futureinvestigation.

关键词： butterflies human impacts hybrid zones movement spatiotemporaldynamics stability

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Irrigation and nitrogen fertiliser optimisation in protected vegetable fields of northern China:Achieving environmental and agronomic sustainability

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Journal of Integrative Agriculture 2024年第3期23卷 1022-1033页

作者： Bingqian Fan Yitao Zhang owen Fenton Karen Daly Jungai Li Hongyuan Wang Limei Zhai Xiaosheng Luo Qiuliang Lei Shuxia Wu Hongbin Liu State Key Laboratory of Efficient Utilization of Arid and Semi-arid Arable Land in Northern China/Key Laboratory of Nonpoint Source Pollution Control Ministry of Agriculture and Rural Affairs/lnstitute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural SciencesBeijing 100081China Institute of Geographic Sciences and Natural Resources Research Chinese Academy of SciencesBeijing 100101China Teagasc Environmental Research CentreWexford Y35Ireland Institute of Plant Nutrition Resources and Environmental SciencesHenan Academy of Agricultural SciencesZhengzhou 450002China

Globally,sub-optimal use of nitrogen (N) fertiliser and elevated N irrigation groundwater have led to high leached nitrate (NO_(3)^(–)) losses from protected vegetable field *** fertiliser and irrigation management in different soil types is crucial to reduce future N loads from such *** present 4-year study examined leached N loads from lysimeter monitoring arrays set up across 18 protected vegetable system sites encompassing the dominant soil types of northern *** treatments applied at each field site were:1) a high N and high irrigation input treatment (HNHI);2) a low N but high irrigation input treatment (LNHI) and 3) a low N with low irrigation input treatment (LNLI).Results showed that the mean annual leached total nitrogen loads from the HNHI,LNHI and LNLI treatments were 325,294 and 257 kg N ha^(–1) in the fluvo-aquic soil,114,100 and 78 kg N ha^(–1) in the cinnamon soil and 79,68 and 57 kg N ha^(–1) in the black soil,*** N dissolved in irrigation water in the fluvo-aquic soil areas was 8.26-fold higher than in the cinnamon areas.A structural equation model showed that N fertiliser inputs and leaching water amounts explained 14.7 and 81.8%of the variation of leached N loads,***,reducing irrigation water by 21.5%decreased leached N loads by 20.9%,while reducing manure N and chemical N inputs by 22 and 25%decreased leached N loads by only 9.5%. This study highlights that protected vegetable fields dominated by fluvo-aquic soil need management to curtail leached N losses in northern China.

关键词： agriculture water quality nitrate groundwater irrigation management

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Value of phosphodiesterase 5 inhibitors as a combination therapy for treating erectile dysfunction:A literature review

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UroPrecision 2024年第1期2卷 9-15页

作者： Christopher K.owen Kareim Khalafalla Run Wang Department of Surgery Division of UrologyMcGovern Medical SchoolHoustonTexasUSA Department of Urology MD Anderson Cancer CenterHoustonTexasUSA

Erectile dysfunction(ED)is increasing in prevalence,with estimates that 50%of men between 40 and 70 years of age suffer from the *** to a wide array of available medical interventions,significant focus has been put on combination therapies that can treat ED refractory to first-line treatments such as phosphodiesterase 5 inhibitors(PDE5is).However,reviews evaluating monotherapy noninferiority and patient satisfaction of monotherapy versus combination therapy are lacking.A thorough PubMed search was performed to evaluate combination therapy in ED *** published between January 2008 and June 2023 were reviewed,including randomized control trials,retrospective analyses,and cohort *** therapies included PDE5i plus another PDE5i,testosterone supplementation,α-blockers,vacuum erectile devices,intracavernosal injections,and low-intensity shockwave *** on this review,PDE5i monotherapy is not inferior to combination therapy and has increased satisfaction,convenience,and ease of use for patients with *** of current literature on combination therapy include small sample size,limited data on patient satisfaction,possible biases,and limited follow-up *** studies will need larger randomized control trials with follow-up times greater than 1 year.

关键词： combination therapy erectile dysfunction intracavernosal injection low-intensity shockwave therapy phosphodiesterase 5 inhibitor vacuum erectile device to 150 million men affected

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鲑鱼变色综合症的生态毒理学测定——与河流污染有关的大西洋鲑鱼病理状况

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人类环境杂志 1997年第8期26卷 497-502页

作者： Bronwen Croce Ronald M.Stagg Nicholas C.Everall David B.Groman Christopher G.Mitchell roger owen 张国梁 Scottish Office Agriculture Severn Trent Water Ltd 大西洋兽医学院苏格兰农业环境与渔业部斯特灵大学

"鲑鱼变色综合症"是一种与大西洋鲑鱼(Salmo salar)的临床黄疸有关的非传染性溶血性贫血症,由多种化学污染物的综合影响而引起。这种病只发生于英国苏格兰阿伯丁郡唐河(River Don,Aberdeenshire)内洄游性成年大西洋鲑鱼种群中,本世纪80... 详细信息

"鲑鱼变色综合症"是一种与大西洋鲑鱼(Salmo salar)的临床黄疸有关的非传染性溶血性贫血症,由多种化学污染物的综合影响而引起。这种病只发生于英国苏格兰阿伯丁郡唐河(River Don,Aberdeenshire)内洄游性成年大西洋鲑鱼种群中,本世纪80年代初曾在那里达到流行病比率。人们认为造纸厂、供油工业区和机场的污流可能是该综合症的诱因。一些实验表明,当受到石油碳氢化合物(如柴油)和树脂酸的连续综合影响时,该综合症的症状能够再现。从1989年起,鲑鱼变色综合症在唐河的野生鲑鱼中再未出现,我们的研究表明这是由于唐河水质的直接改善。该病是多种污染物综合引起生物效应的很好的例证。而在单一污染物质影响下,这种作用并不明显。本文描述了确定病因的方法。

关键词：鲑鱼变色综合症生态毒理学污染毒理学病因

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Flexible tuning of multifocal holographic imaging based on electronically controlled metasurfaces

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Photonics Research 2024年第1期12卷 61-69页

作者： owen ZENG CHENXIA LI BO FANG ZHI HONG XUFENG JING Institute of Optoelectronic Technology China Jiliang UniversityHangzhou 310018China Centre for THz Research China Jiliang UniversityHangzhou 310018China College of Metrology&Measurement Engineering China Jiliang UniversityHangzhou 310018China

Programmable hyper-coded holography has the advantage of being programmable as well as being flexibly *** coded metamaterials with excellent electromagnetic modulation capability and the ability to control the phase to modulate the spatial radiation field through external excitation in the form of switching can be used to realize low-cost digital *** design a 1-bit encoded programmable metasurface,which is electrically connected to control the PIN diode in the switching state and to switch the condition of each metasurface cell between“0”and“1.”Using the designed programmable metasurface,we can randomly encode the cell structure to realize single-focus focusing,multi-focusing,and simple holographic letter *** on the nonlinear holographic model,we employ the Gerchberg-Saxton improvement algorithm to modulate the energy distribution at the focus by adjusting the phase ***,we introduce the Fourier convolution principle to regulate the holographic imaging focus flexibly.

关键词： holographic letter excitation

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高绩效管理的RAMP模式

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经理人 2024年第8期 74-77页

作者：乔·欧文不详

管理者不需要每周一早上都站在办公桌前,向大家发表鼓舞人心和励志的演讲。要实现激励和高绩效的目标,可以用四个缩写字母来概括:支持性关系(supportiverelationships,R)、自主权(autonomyandaccountability,A)、精通(masteryandgrowth... 详细信息

管理者不需要每周一早上都站在办公桌前,向大家发表鼓舞人心和励志的演讲。要实现激励和高绩效的目标,可以用四个缩写字母来概括:支持性关系(supportiverelationships,R)、自主权(autonomyandaccountability,A)、精通(masteryandgrowth,M)、目标感(purpose,P)。

关键词：高绩效支持性关系自主权

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Modelling internal air systems ingas turbine engines

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航空动力学报 2007年第4期22卷 505-520页

作者： J Michael owen Department of Mechanical Engineering University of Bath

Rotating-disc systems can be used to model,experimentally and computationally,the flow and heat transfer that occur inside the internal cooling-air systems of gas turbine *** rotating-disc systems have been used successfully to simplify and understand some of the complex flows that occur in internal-air systems,and designers have used this insight to improve the cooling effectiveness,thereby increasing the engine efficiency and reducing the *** this review paper,three important cases are considered:hot-gas ingress;the pre-swirl system;and buoyancy-induced ***,or ingestion,occurs when hot gas from the mainstream gas path is ingested into the wheel-space between the turbine disc and its adjacent *** seals are fitted at the periphery of the system,and sealing flow is used to reduce or prevent ***,too much sealing air reduces the engine efficiency,and too little can cause serious overheating,resulting in damage to the turbine rim and blade *** the flow is three-dimensional and unsteady,there are encouraging signs that simple ‘orifice models’ could be used to estimate the amount of ingress into the *** a pre-swirl system,the cooling air for the gas-turbine blades is swirled by stationary nozzles,and the air is delivered to the blades via receiver holes in the rotating turbine *** the air reduces its temperature relative to the rotating blades,and the designer needs to calculate the air temperature and pressure drop in the *** designer also needs to calculate the effect of this swirling flow on the heat transfer from the turbine disc to the air,as this has a significant effect on the temperature distribution and stresses in the *** experimental and computational studies have given a better understanding of the flow and heat transfer in these ***-induced flow occurs in the cavity between two co-rotating compressor discs when the temperature of the discs is higher than

关键词：燃气涡轮机车空气动力学数学模型旋转式圆盘系统

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Prime gradient noise

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Computational Visual Media 2021年第3期7卷 349-362页

作者： Sheldon Taylor owen Sharpe Jiju Peethambaran Graphics&Spatial Computing Lab Dept.of Math&CSSaint Mary’s UniversityHailifaxNSCanadaB3H3C3

Procedural noise functions are fundamental tools in computer graphics used for synthesizing virtual geometry and texture ***,a procedural noise function should be compact,aperiodic,parameterized,and randomly *** lattice noise functions such as Perlin noise,however,exhibit periodicity due to the axial correlation induced while hashing the lattice vertices to the *** this paper,we introduce a parameterized lattice noise called prime gradient noise(PGN)that minimizes discernible periodicity in the noise while enhancing the algorithmic *** utilizes prime gradients,a set of random unit vectors constructed from subsets of prime numbers plotted in polar coordinate *** map axial indices of lattice vertices to prime gradients,PGN employs Szudzik pairing,a bijection F:N2→*** of Szudzik pairing functions are used in higher *** the core of PGN is the ability to parameterize noise generation though prime sequence offsetting which facilitates the creation of fractal noise with varying levels of heterogeneity ranging from homogeneous to hybrid multifractals.A comparative spectral analysis of the proposed noise with other noises including lattice noises show that PGN significantly reduces axial correlation and hence,periodicity in the noise *** demonstrate the utility of the proposed noise function with several examples in procedural modeling,parameterized pattern synthesis,and solid texturing.

关键词： procedural noise procedural texture Perlin noise prime numbers

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Detecting the ?ngerprints of observed climate change on surface ozone variability

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Science Bulletin 2019年第6期64卷 359-360页

作者： owen R.Cooper Cooperative Institute for Research in Environmental Sciences University of Colorado NOAA Earth System Research Laboratory

At the surface, tropospheric ozone is an air pollutant that adversely impacts human health, natural vegetation and crop yield and quality. This important trace gas also plays key roles as a greenhouse gas, and as the primary source of the hydroxyl (OH) radical, which determines the lifetime of many other trace gases in the atmosphere. Tropospheric ozone has a variety of sources including photochemical production from anthropogenic and naturally occurring precursor gases, and transport from the stratosphere. As a result of 让s high reactivity and its wide range of sources,*sozone lifetime can vary from minutes in the polluted boundary layer to several weeks in the mid- and upper troposphere.

关键词： tropospheric ozone greenhouse gas polluted boundary layer

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