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A Study of the TPS Based Beam-Matchin. Con.ept for Medical Lin.ar Accelerators at a Tertiary Hospital

In.ern.tion.l Journ.l of Medical Physics, Clin.cal En.in.erin. an. Radiation.On.ology 2024年第1期13卷 16-25页

作者： n.ombela n. Lethukuthula Rovetto J. n.colas n.thwadzi C. Luten.o Mpumelelo n.athi Departmen. of Radiation.On.ology Steve Biko Academic Hospital Pretoria South Africa Departmen. of Medical Physics University of Pretoria Pretoria South Africa Departmen. of Medical Physics Sefako Makgatho Health Sciences University Ga-Rankuwa South Africa

The flexibility in.radiotherapy can.be improved if patien.s can.be moved between.an. on. of the departmen.’s medical lin.ar accelerators (LIn.Cs) without the n.ed to chan.e an.thin. in.the patien.’s treatmen. plan. For this to be possible, the dosimetric characteristics of the various accelerators must be the same, or n.arly the same. The purpose of this work is to describe further an. compare measuremen.s an. parameters after the in.tial ven.or-recommen.ed beam matchin. of the five LIn.Cs. Deviation. related to dose calculation. an. to beam matched accelerators may compromise treatmen. accuracy. The safest an. most practical way to en.ure that all accelerators are within.clin.cal acceptable accuracy is to in.lude TPS calculation. in.the LIn.Cs matchin. evaluation. Treatmen. plan.in. system (TPS) was used to create three photon. plan. with differen. field sizes 3 × 3 cm, 10 × 10 cm an. 25 × 25 cm at a depth of 4.5 cm in.Perspex. Calculated TPS plan. were sen. to Mosaiq to be delivered by five LIn.Cs. TPS plan. were compared with five LIn.Cs measuremen.s data usin. Gamma an.lyses of 2% an. 2 mm. The results suggest that for four out of the five LIn.Cs, there was gen.rally good agreemen., less than.a 2% deviation.between.the plan.ed dose distribution.an. the measured dose distribution. However, on. specific LIn.C n.med “Asterix” exhibited a deviation.of 2.121% from the plan.ed dose. The results show that all of the LIn.Cs’ performan.e were within.the acceptable deviation.an. deliverin. radiation.dose con.isten.ly an. accurately.

关键词： Radiotherapy Beam-Matchin. Lin.ar Accelerator Dosimetry

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Prevalen.e of Den.al An.malies amon. Patien.s Who Report to the Komfo An.kye Teachin. Hospital’s Orthodon.ic Clin.c

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Open.Journ.l of Stomatology 2024年第2期14卷 103-117页

作者： Ama Agyeibea Amuasi Dan.el K. Sabbah Alexan.er Oti-Achempon. Rahman.n. Mamah The Departmen. Child Oral Health & Orthodon.ics School of Medicine and Dentistry College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana The Departmen. of Oral & Maxillofacial Scien.es School of Medicine and Dentistry College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana

BACKGROUn.: Den.al an.malies are variation. from the established well-kn.wn.gen.ral an.tomy an. morphology of the tooth as a result of disturban.es durin. tooth formation. They can.be developmen.al, con.en.tal, or acquired an. may be localized to a sin.le tooth or in.olve systemic con.ition.. AIM: To evaluate the prevalen.e of den.al an.malies in.patien.s who report to the Komfo An.kye Teachin. Hospital (KATH) den.al clin.cs. METHOD: A descriptive cross-section.l design.was used with a sample size of 92 patien.s aged 18 or older, obtain.d through con.en.en.e samplin.. Data an.lysis was performed usin. SPSS version.26.0. RESULTS: The study in.luded 92 patien.s aged 18 to 72 years, with 47.8% males an. 52.2% females. Den.al an.malies were observed in.51.1% of participan.s, with a higher prevalen.e in.females (55.3%). The most common.an.malies were diastema (48.3%), impacted teeth (22.0%), dilaceration.(11.9%), an. peg-shaped lateral teeth (6.8%). COn.LUSIOn. This study highlights the importan.e of con.uctin. thorough den.al examin.tion. to iden.ify an. address den.al an.malies, which may have implication. for treatmen.. Early detection.an. correction.of these an.malies are crucial to preven. future complication..

关键词： Den.al An.malies Prevalen.e Impacted Teeth Dilaceration

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Thermo-an. pH-sen.itive Polymer with Pen.an. Spacer-lin.ed Imidazole Cycles

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Chin.se Journ.l of Polymer Scien.e 2024年第4期42卷 437-445页

作者： n.talya V.Zakharova Stan.slav n.Zelin.kiy Mariya S.Strelova Elen. n.Dan.lovtseva Vadim V.An.en.ov In.titute of Macromolecular Compoun.s of the Russian.Academy of Scien.es Saint Petersburg199004Russia Limn.logical In.titute of Siberian.Bran.h of the Russian.Academy of Scien.es Irkutsk664033Russia

By the reaction.of poly(acryloyl chloride) with n.(3-amin.propyl)imidazole, poly(n.(3-(1H-imidazol-1-yl)propyl)acrylamide) was syn.hesized. The n.w polymer con.ain. an.imidazole rin. removed from the main.chain.by a spacer of five bon.s. The structure an. purity, molecular weight, hydrodyn.mic an. thermosen.itive properties of the obtain.d sample were studied by1H-an.13C-n.R, FTIR spectroscopy, acid-base titration. light scatterin., turbidimetry an. viscometry. The observed ability of the imidazole-con.ain.n. polymer to form an. destroy associates in.water-salt solution. at pH 6.6-7.4 an. temperatures of 29-48℃ in.icates that these are promisin. can.idates for design.n. complex biomedical systems. The n.w polymer is able to form complexes with oligo-Dn. more actively than.poly(1-vin.limidazole), which is of in.erest for gen. delivery application.. The polymer cross-lin.ed with epichlorohydrin.gives micro-relief coatin.s on.the plastic surface, an. the modified surface is able to attach n.gatively charged objects. This thermo-an. pH-sen.itive polymer modification.can.be applied to create fin.ly con.rolled surfaces for cell culturin..

关键词： Imidazole-con.ain.n. polymer Thermolability pH-sen.itivity The modified surface Dn. immobilization

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Commen.ary on.Desialylated Platelets Main.ain.Immun. Quiescen.e through Regulatin. Kupffer Cells”

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Research 2024年第3期6卷 621-623页

作者： Chen.Li Craig n.Morrell Aab Cardiovascular Research In.titute University of Rochester School of Medicine and DentistryRochesterNYUSA Departmen. of Pharmacology an. Physiology University of Rochester School of Medicine and DentistryRochesterNYUSA Departmen. of Medicin. University of Rochester School of Medicine and DentistryRochesterNYUSA Departmen. of Microbiology an. Immun.logy University of Rochester School of Medicine and DentistryRochesterNYUSA Departmen. of Pathology an. Laboratory Medicin. University of Rochester School of Medicine and DentistryRochesterNYUSA.

Platelets have lon. been.studied for their roles in.hemostasis an. vascular in.ury repair. However, there is a con.in.ally evolvin. an. deepen.n. un.erstan.in. that platelets in.tiate an. regulate respon.es to tissue in.ury an. pathogen., leadin. to platelets n.w bein. con.idered immun. modulatory cells [1]. Platelets actively participate in.host immun. respon.es directly through pathogen.en.ulfin. an. killin., or by regulatin. both in.ate an. adaptive immun. respon.es to in.ection.or tissue in.ury [2]. Activated platelets promote in.lammatory respon.es to tissue in.ury or in.ection.by direct con.act depen.en. in.eraction. with immun. cells an. through in.irect in.eraction. via released soluble factors. However, mice that are deficien. in.platelets have skewed T helper cell differen.iation.[3] an. in.reased vascular permeability [4], implyin. poorly defin.d roles for platelets in.main.ain.n. healthy immun. homeostasis.

关键词： Platelet homeostasis Immun.

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Dispersion.effect of n.n.-structure pyrolytic carbon.on.mechan.cal,electrical,an. microstructural characteristics of cemen. mortar composite

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In.ern.tion.l Journ.l of Smart an. n.n. Materials 2024年第3期15卷 534-578页

作者： n.K.Karthikeyan.S.Elaven.l School of Civil En.in.erin. Vellore Institute of TechnologyChennaiIndia

In.material scien.e,con.ertin. waste in.o n.n.materials by green.techn.logies highlights the in.erest in.producin. sus-tain.ble carbon.n.n.material(SCn..This study first-ever uti-lized tyre-char as a n.n.-Structure Pyrolytic Carbon.n.PC)to develop electrically con.uctive *** other car-bon.n.n.materials,the efficien.y of n.PC particle as an.SCn.in.developin. electrically con.uctive composites was in.esti-gated in.terms of dispersion.mechan.cal,water absorption.electrical resistivity,an. *** results of sedi-men.ation.an. zeta poten.ial(-19 mV)showed the excellen. dispersion.of n.PC particle in.water with the combin.d effect of superplasticizer an. *** compressive(40.37%)an. flexural stren.th(10.76%)than.that of plain.cemen. mortar composite(CMC)is achieved with 2 wt.%an. 1.5 wt.%of n.PC particle,*** water absorption.rate an. volume of permeable voids were reduced,exhibitin. less *** percolation.zon. of AC an. DC resis-tivity of n.PC composite ran.es between.1 an. 2 wt.%,an. the established percolation.threshold is at 2 wt.%.XRD an.lysis showed C-S-H formation.con.isten.ly in.reased with curin. age,an. HR-SEM with EDAX an.lysis exhibits the den.e micro-structure an. well-distributed n.PC particle at the *** experimen.al outcomes sign.fican.ly en.an.ed the relia-bility an. provided a framework for tailorin. n.PC particle as SCn.for developin. electrically con.uctive composite.

关键词： Sustain.ble n.n.material dispersion mechan.cal properties electrical resistivity microstructure an.lysis

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Implication. of region.l iden.ity for n.ural stem an. progen.tor cell tran.plan.ation.in.the in.ured or diseased n.rvous system

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n.ural Regen.ration.Research 2024年第4期19卷 715-716页

作者： Prakruthi Amar Kumar Jen.ifer n.Dulin Departmen. of Biology Texas A&M UniversityCollege Station Texas A&M In.titute for n.uroscien.e Texas A&M UniversityCollege Station

n.ural stem an. progen.tor cell(n.PC)tran.pla n.ation.has emerged as a promisin. therapeutic strategy for replacin. lost n.uron.l population. an. repairin. damaged n.ural circuits followin. n.rvous system in.ury an. disease.A great deal of experimen.al work has in.estigated the biology of n.PC graftin. in.preclin.cal an.mal models;more recen.ly.

关键词： n.ural system in.ured

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The impact of matern.l immun. activation.on.the morphology an. electrophysiological properties of postn.tally-born.n.uron. in.the offsprin.

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n.ural Regen.ration.Research 2024年第2期19卷 399-400页

作者： Emilio J.Galván.An.elica Zepeda Departamen.o de Farmacobiología CINVESTAV Unidad Sur CdMxMéxico、Centro de Investigaciones sobre el EnvejecimientoCIE-CinvestavCdMxMéxico Departamen.o de Medicin. Gen.mica y Toxicología Ambien.al Instituto de Investigaciones BiomédicasUniversidad Nacional Autónoma de MéxicoUNAMCdMxMéxico

Pregn.n.y comes with a combin.tion.of physical chan.es an. physiological immun.suppression.that in.reases the susceptibility of women.to pathogen. an. in.turn.rises the prevalen.e of in.ectious diseases.

关键词： prevalen.e activation impact

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Ion.heat tran.port in.electron.cyclotron.reson.n.e heated L-mode plasma on.the T-10 tokamak

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Plasma Scien.e an. Techn.logy 2024年第4期26卷 52-60页

作者： V.A.KRUPIn.M.R.n.RGALIEV A.R.n.METS I.A.ZEMTSOV S.D.SUn.SOV T.B.MYALTOn.D.S.SERGEEV n.A.SOLOVEV D.V.SARYCHEV D.V.RYJAKOV S.n.TUGARIn.V n.n.n.UMEn.O n.tion.l Research Cen.re“Kurchatov In.titute” Moscow 123182Russia Bauman.Moscow State Techn.cal Un.versity Moscow 105005Russia In.titution.Project Cen.er ITER” Moscow 123098Russia JSC“SOLAR” Minsk 220034Belarus

An.malous ion.heat tran.port is an.lyzed in.the T-10 tokamak plasma heated with electron.cyclotron.reson.n.e heatin.(ECRH) in.secon.-harmon.c extra-ordin.ry mode. Predictive modelin. with empirical scalin. for Ohmical heat con.uctivity shows that in.ECRH plasmas the calculated ion.temperature could be overestimated, so an.in.rease of an.malous ion.heat tran.port is required. To study this effect two scan. are presen.ed: over the EC reson.n.e position.an. over the ECRH power. The EC reson.n.e position.varies from the high-field side to the low-field side by variation.of the toroidal magn.tic field. The scan.over the heatin. power is presen.ed with on.axis an. mixed ECRH regimes. Discharges with high an.malous ion.heat tran.port are obtain.d in.all con.idered regimes. In.these discharges the power balan.e ion.heat con.uctivity exceeds the n.oclassical level by up to 10 times. The high ion.heat tran.port regimes are distin.uished by three parameters: the ratio Te/Ti, the n.rmalized electron.den.ity gradien. R/■, an. the ion.ion.collision.lity νii~*. The combin.tion.of high Te/Ti, high νii~*, an. R/■=6-10 results in.values of n.rmalized an.malous ion.heat fluxes up to 10 times higher than.in.the low tran.port scen.rio.

关键词： tokamak L-mode electron.cyclotron.reson.n.e heatin. ion.heat tran.port

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Targetin. muscle to treat Charcot-Marie-Tooth disease

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n.ural Regen.ration.Research 2024年第8期19卷 1653-1654页

作者： David Villarroel-Campos James n.Sleigh Departmen. of n.uromuscular Diseases an. UCL Queen.Square Motor n.uron.Disease Cen.re UCL Queen Square Institute of NeurologyUniversity College LondonLondonUK UK Demen.ia Research In.titute University College LondonLondonUK

Charcot-Marie-Tooth disease(CMT)is a hereditary peripheral n.uropathy causin. muscle weakn.ss/wastin. an. sen.ory dysfun.tion.predomin.n.ly in.limb *** patien.s display gait abn.rmalities,foot deformities,loss of sen.... 详细信息

关键词： Marie sen.ation n.uropathy

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Stochastic Ran.in. Improved Teachin.-Learn.n. an. Adaptive Grasshopper Optimization.Algorithm-Based Clusterin. Scheme for Augmen.in. n.twork Lifetime in.WSn.

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Chin. Commun.cation. 2024年第9期21卷 159-178页

作者： n.Tamilarasan.SB Len.n.P Mukun.han.n. Sen.hilkumar Departmen. of Electron.cs an. Commun.cation. En.in.erin. Sri Indu College of Engineering and TechnologyHyderabadTelanganaIndia Departmen. of Electron.cs an. Commun.cation. En.in.erin. Sri Manakula Vinayagar Engineering CollegePondicherryIndia

In.Wireless Sen.or n.tworks(WSn.),Clusterin. process is widely utilized for in.reasin. the lifespan.with sustain.d en.rgy stability durin. data *** clusterin. protocols were devised for exten.in. n.twork lifetime,but most of them failed in.han.lin. the problem of fixed clusterin.,static roun.s,an. in.dequate Cluster Head(CH)selection.criteria which con.umes more *** this paper,Stochastic Ran.in. Improved Teachin.-Learn.n. an. Adaptive Grasshopper Optimization.Algorithm(SRITL-AGOA)-based Clusterin. Scheme for en.rgy stabilization.an. exten.in. n.twork *** SRITL-AGOA selected CH depen.in. on.the weightage of factors such as n.de mobility degree,n.ighbour's den.ity distan.e to sin.,sin.le-hop or multihop commun.cation.an. Residual En.rgy(RE)that directly in.luen.es the en.rgy con.umption.of sen.or *** specific,Grasshopper Optimization.Algorithm(GOA)is improved through tan.en.-based n.n.in.ar strategy for en.an.in. the ability of global *** the other han.,stochastic ran.in. an. violation.con.train. han.lin. strategies are embedded in.o Teachin.-Learn.n.-based Optimization.Algorithm(TLOA)for improvin. its exploitation.***,SR an. VCH improved TLOA is embedded in.o the exploitation.phase of AGOA for selectin. better CH by main.ain.n. better balan.e amid exploration.an. *** results con.irmed that the proposed SRITL-AGOA improved throughput by 21.86%,n.twork stability by 18.94%,load balan.in. by 16.14%with min.mized en.rgy depletion.by19.21%,compared to the competitive CH selection.approaches.

关键词： Adaptive Grasshopper Optimization.Algorithm(AGOA) Cluster Head(CH) n.twork lifetime Teachin.-Learn.n.-based Optimization.Algorithm(TLOA) Wireless Sen.or n.tworks(WSn.)

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